21 completed, 6 not yet recruiting, 5 recruiting, 5 unknown. 40 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 40 | Completed 21, Not yet recruiting 6, Recruiting 5, Unknown 5, Active not recruiting 3 |
Follow Emergence Agitation: new trials by email Literature Review of Emergence Agitation trials Research Report on Emergence Agitation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Dexmedetomidine Combined With Esketamine for Emergence Quality After Suspension Laryngoscopy Dexmedetomidin, Esketamine - Emergence Agitation, Vocal Cord Polyps | Not applicable | Not yet recruiting | The First Hospital of Jilin University | 134 | 2026-09-01 | 2026-10-19 |
| Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients immersive virtual reality, standard sedation - Hip Osteoarthritis, Hip Arthroplasty Replacement | Not applicable | Not yet recruiting | Menoufia University | 40 | 2026-07-10 | 2026-07-15 |
| Intranasal Dexmedetomidine vs Oral Midazolam for Premedication in Pediatric Surgery Dexmedetomidine, Midazolam - Pediatric Anesthesia, Preoperative Anxiety | Not applicable | Recruiting | Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital | 84 | 2026-05-05 | 2026-05-14 |
| Minimal- Versus High-Flow Sevoflurane and Emergence Agitation in Pediatric Surgery caudal block - Postoperative Agitation, Emergence Agitation | Not applicable | Active not recruiting | Ankara City Hospital Bilkent | 80 | 2026-04-22 | 2026-06-09 |
| Effect of Lollipop on Emergence Delirium in Pediatric Patients Undergoing General Anesthesia Lollipop - Emergence Agitation | Not applicable | Completed | Udayana University | 66 | 2026-04-10 | 2026-10-29 |
| Effect of Intranasal Dexmedetomidine on the Incidence of Emergence Agitation in Children Undergoing Strabismus Surgery high dex group, low dex group - Dexmedetomidine, Emergence Agitation | Not applicable | Completed | Alexandria University | 150 | 2026-04-06 | 2026-10-22 |
| Auricular Acupressure for Reducing Postoperative Emergence Agitation in Preschool Children Auricular acupressure, sham auricular acupressure - Emergence Agitation | Not applicable | Not yet recruiting | Beijing Tongren Hospital | 110 | 2026-04-01 | 2026-03-16 |
| Transcutaneous Auricular Vagus Nerve Stimulation for Prevention of Emergence Agitation and Delirium in Children Undergoing Tonsillectomy and Adenoidectomy Active taVNS Group, Sham stimulation group - Emergence Agitation, Emergence Delirium | Not applicable | Not yet recruiting | The First Affiliated Hospital of Zhejiang Chinese Medical University | 120 | 2026-02-24 | 2026-02-06 |
| Preemptive Intravenous Micro-dose Dexmedetomidine to Prevent Emergence Agitation in Adult Patients Undergoing Septoplasty Surgeries Dexmedetomidine, Saline - Emergence Agitation | Not applicable | Completed | Tanta University | 120 | 2026-01-10 | 2026-10-06 |
| Comparison of Emergence Agitation Between Remimazolam With Flumazenil and Propofol-based Total Intravenous Anesthesia in Patients Undergoing Nasal Surgery Remimazolam with Flumazenil, Propofol - Emergence Agitation | Not applicable | Not yet recruiting | Seoul National University Hospital | 204 | 2026-01-01 | 2025-12-04 |
| The Effects of Three Different Anesthetic Methods on Postoperative Agitation SEVOFLURANE, TIVA, CIVIA - Emergence Agitation, Septoplasty Surgeries | Not applicable | Completed | Inonu University | 3 | 2025-12-25 | 2026-05-07 |
| The Effect of Dexmedetomidine Versus Lidocaine on Emergence Agitation. Dexmedetomidine, Lidocaine - Emergence Agitation | Not applicable | Not yet recruiting | Fayoum University | 80 | 2025-12-21 | 2026-01-21 |
| Effects of Preoperative Education on Anxiety and Emergence Agitation Preoperative Emergence-Focused Education, Standard Perioperative Care - Preoperative Anxiety, Emergence Agitation | Not applicable | Active not recruiting | Yeditepe University | 80 | 2025-12-12 | 2026-01-16 |
| Emergence Agitation Neostigmine + Atropine, Sugamadex - Emergence Agitation, Nasal Surgery | Not applicable | Active not recruiting | Ain Shams University | 486 | 2025-10-30 | 2025-11-28 |
| Preemptive Oral Lactium to Prevent Emergence Agitation Lactium, Placebo control - Lactium, Emergence Agitation | Not applicable | Completed | Tanta University | 135 | 2025-09-22 | 2026-01-13 |
| Efficacy of Ultrasound-guided Greater Auricular Nerve Block in Preventing Postoperative Emergence Agitation in Pediatric Patients Undergoing Microscopic Middle Ear Surgery. ultrasound-guided greater auricular nerve block (GANB) - Emergence Agitation, Emergence Delirium, Anesthesia | Not applicable | Recruiting | Fayoum University | 74 | 2025-08-01 | 2026-02-27 |
| Effect of Preoperative Oral Magnesium on Emergence Agitation Magnesium, Placebo control - Magnesium, Emergence Agitation | Not applicable | Completed | Tanta University | 120 | 2025-07-25 | 2026-04-03 |
| Comparison of Effect of Dexmedetomidine and Midazolam on Emergence Agitation Dexmedetomidine, Midazolam - Emergence Agitation | Not applicable | Completed | Muhammad Aamir Latif | 146 | 2025-07-01 | 2026-02-06 |
| Oral Melatonin Versus Nebulized Dexmedetomidine on Emergence Agitation in Children Undergoing Adenotonsillectomy Normal saline, Oral melatonin syrup, Nebulized dexmedetomidine - Oral Melatonin, Nebulized Dexmedetomidine | Not applicable | Recruiting | Tanta University | 96 | 2025-07-01 | 2026-01-16 |
| Prevention of Emergence Agitation in Rhinoplasty With Subanesthetic Propofol and Single-Dose Dexmedetomidine: A Prospective Double-Blind Clinical Study Dexmedetomidine, Propofol - Emergence Agitation | Not applicable | Recruiting | Yuzuncu Yil University | 80 | 2025-04-15 | 2025-08-27 |
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Emergence Delirium (40) · Pain, Postoperative (3) · Anxiety Disorders (1) · Osteoarthritis, Hip (1) · Pain (1) · Patient Satisfaction (1)
Confusion (40) · Delirium (40) · Mental Disorders (40) · Nervous System Diseases (40) · Neurobehavioral Manifestations (40) · Neurocognitive Disorders (40) · Neurologic Manifestations (40) · Pathologic Processes (40) · Pathological Conditions, Signs and Symptoms (40) · Postoperative Complications (40) · Signs and Symptoms (40) · Pain (3) · Arthritis (1) · Behavior (1) · Health Behavior (1)
Dexmedetomidine (9) · Saline Solution (5) · Propofol (4) · Sevoflurane (4) · Bupivacaine (3) · Fentanyl (2) · Magnesium Sulfate (2) · Midazolam (2) · Remifentanil (2) · remimazolam (2) · Analgesia (1) · Atropine (1) · Esketamine (1) · Flumazenil (1) · Laryngeal Masks (1)
Tanta University (4) · Ain Shams University (2) · Assiut University (2) · Fayoum University (2) · Inonu University (2) · Mansoura University (2) · Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital (2) · Yeungnam University College of Medicine (2) · Yuzuncu Yil University (2) · Ahi Evran University Education and Research Hospital (1) · Alexandria University (1) · Ankara City Hospital Bilkent (1) · Beijing Tongren Hospital (1) · Duke University (1) · Henan Provincial People's Hospital (1)
Egypt (14) · Turkey (Türkiye) (9) · China (6) · Pakistan (2) · South Korea (2) · Indonesia (1) · Saudi Arabia (1) · Thailand (1) · United States (1)
Ambreen Khan, FCPS (1) · Amir Mostafa Shabana, MD (1) · Dr AhsUn Waqar, Consultant (1) · Fatma Acil, M.D. (1) · Gehan Ad Tarabeah, MD (1) · Guyan Wang (1) · Heather J Frederick, MD (1) · Hesham Ah Abdel Mohaiemn, MD (1) · I Putu Kurniyanta, MD, PhD, Sp.An (1) · Khaled E Tolba, MBBCH (1) · Madiha Ashraf (1) · Marwa Ib Abdo, MD (1) · Nureddin Yuzkat, Associate professor (1)
PMID 15114210, PMID 20526708, PMID 25535538, PMID 32048203, PMID 33588751, PMID 35012708, PMID 38762729, PMID 39366653, PMID 42432924, PMID 42688410, PMID 9416712