28 completed, 5 terminated, 4 withdrawn, 1 recruiting. 39 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 39 | Completed 28, Terminated 5, Withdrawn 4, Recruiting 1, Unknown 1 |
Follow Dyspnea: new trials by email Literature Review of Dyspnea trials Research Report on Dyspnea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bronchodilators and Lung Mechanics During Exercise in COPD Bronchodilators inhalation, Placebo - COPD | Phase 4 | Recruiting | Dr. J. Alberto Neder | 25 | 2024-11-10 | 2025-02-13 |
| The Effect of Nebulized Epinephrine in Asthma Exacerbation in Pediatric Age Group With the Standard Treatment Compared to Standard Treatment Using Improvement PRAM Score as a Primary Outcome nebulized epinephrine, Salbutamol - Shortness of Breath, Asthma in Children | Phase 4 | Completed | Oman Medical Speciality Board | 30 | 2023-10-15 | 2025-06-06 |
| Gastric Sleeve-Induced Weight Loss on Shortness of Breath in Obesity Bariatric surgery, Medical weight loss - Dyspnea, Quality of Life | Phase 4 | Withdrawn | University of California, Los Angeles | 2023-07-09 | 2025-02-14 | |
| Mechanisms for Dyspnea on Exertion in Children With Obesity and Asthma: Distinct Physiological Phenotypes Control, Albuterol - Asthma in Children, Dyspnea; Asthmatic | Phase 4 | Withdrawn | Ohio State University | 2023-07-01 | 2023-11-07 | |
| Triple vs High Dose Inhaled CORticosteroids To compare in both treatment arms the percentage of patients controlled at week 52. - Asthma | Phase 4 | Withdrawn | Galaxia Empírica | 2023-06-01 | 2025-09-04 | |
| Morphine or Fentanyl for Refractory Dyspnea in COPD Fentanyl, Morphine Retard, Placebo patch - COPD | Phase 4 | Completed | Huib A.M. Kerstjens | 59 | 2019-11-15 | 2025-06-04 |
| Morphine for Treatment of Dyspnea in Patients With COPD sustained release morphine, placebo - Pulmonary Disease, Chronic Obstructive | Phase 4 | Completed | Maastricht University Medical Center | 124 | 2016-11-16 | 2019-09-04 |
| Ultibro® Versus Spiriva® Alone to Reduce Exertional Dyspnea in Patients With Moderate to Severe COPD Ultibro®, Spiriva® - COPD | Phase 4 | Completed | Laval University | 50 | 2016-06-01 | 2019-06-07 |
| Efficacy of Intermittent Tiotropium in Early Childhood Wheezing Tiotropium Bromide, Fluticasone Propionate, Salbutamol - Wheezy Bronchitis, Asthmatic Bronchitis | Phase 4 | Terminated | Helsinki University Central Hospital | 80 | 2016-04-20 | 2024-09-19 |
| Palliation of Dyspnea With Morphine in Patients With Interstitial Lung Disease Morphine hydrochloride, Placebo - Interstitial Lung Disease, Dyspnea | Phase 4 | Completed | University of Aarhus | 36 | 2016-01-01 | 2019-04-10 |
| Single Dose Ultibro Breezhaler by Sd-DPI Versus Ipratropium/Salbutamol by Nebulizer in COPD indacaterol/glycopyrronium 110/50 Breezhaler®, Placebo by Breezhaler®, ipratropium/salbutamol 0,5 mg, 2,5 mg by nebulisation - COPD | Phase 4 | Completed | Wouter H. van Geffen | 40 | 2015-12-01 | 2017-10-11 |
| Dialogue Aimed at Reducing Anxiety in Patients With Severe COPD Psychoeducative intervention - Chronic Obstructive Pulmonary Disease, Anxiety | Phase 4 | Completed | Nordsjaellands Hospital | 66 | 2015-02-01 | 2016-06-23 |
| The Evaluation of FeNO for Predicting Response to ICS in Subjects With Non-specific Respiratory Symptoms Qvar (100 mcg) - Asthma | Phase 4 | Completed | Research in Real-Life Ltd | 360 | 2014-05-01 | 2017-04-25 |
| The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic Bronchitis Roflumilast, Placebo - COPD, Chronic Bronchitis | Phase 4 | Completed | Johns Hopkins University | 12 | 2013-03-18 | 2017-07-27 |
| Ranolazine for the Treatment of Chest Pain in HCM Patients Ranolazine - Hypertrophic Cardiomyopathy | Phase 4 | Completed | Duke University | 14 | 2012-11-01 | 2017-03-03 |
| Effect of Ketoconazole on Breathlessness ketoconazole, inert powder - Chronic Obstructive Pulmonary Disease | Phase 4 | Completed | Dartmouth-Hitchcock Medical Center | 20 | 2011-06-01 | 2018-06-01 |
| Effect of Indacaterol Maleate in Chronic Obstructive Pulmonary Disease (COPD) on Lung Volume and Related Dyspnea Indacaterol maleate, Placebo - COPD, Lung Diseases | Phase 4 | Completed | University of Milan | 60 | 2011-05-01 | 2014-10-29 |
| Ranolazine in Ischemic Cardiomyopathy Ranexa, Placebo - Cardiomyopathy, Chest Pain | Phase 4 | Completed | Midwest Cardiovascular Research Foundation | 28 | 2011-04-01 | 2024-12-09 |
| Fluticasone Propionate/Salmeterol Combination 250/50 DISKUS in the Exercise Endurance Time in Patients With Chronic Obstructive Pulmonary Disease fluticasone propionate/salmeterol inhalation powder DISKUS 250/50, tiotropium bromide inhalation powder HandiHaler - Pulmonary Disease, Chronic Obstructive | Phase 4 | Completed | GlaxoSmithKline | 255 | 2010-07-19 | 2017-11-08 |
| Effectiveness of Inhaled Corticosteroids in Preschool Children With Acute Dyspnea and Wheeze Beclomethasone, Placebo - Wheezing, Dyspnea | Phase 4 | Terminated | Princess Amalia Children's Clinic | 7 | 2010-05-01 | 2018-01-04 |
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Pulmonary Disease, Chronic Obstructive (15) · Heart Failure (6) · Motor Activity (6) · Asthma (4) · Respiratory Sounds (4) · Cough (3) · Lung Diseases (3) · Cardiomyopathies (2) · Chest Pain (2) · Lung Diseases, Interstitial (2) · Airway Obstruction (1) · Anxiety Disorders (1) · Bronchiolitis (1) · Bronchiolitis Obliterans Syndrome (1)
Pathological Conditions, Signs and Symptoms (39) · Respiration Disorders (39) · Signs and Symptoms (39) · Signs and Symptoms, Respiratory (39) · Respiratory Tract Diseases (38) · Lung Diseases (23) · Lung Diseases, Obstructive (20) · Disease Attributes (16) · Pathologic Processes (16) · Chronic Disease (15) · Cardiovascular Diseases (10) · Heart Diseases (9) · Behavior (7) · Bronchial Diseases (7) · Immune System Diseases (6)
Natriuretic Peptide, Brain (4) · Albuterol (3) · Fluticasone (3) · indacaterol (3) · Beclomethasone (2) · Ipratropium (2) · Ranolazine (2) · Tiotropium Bromide (2) · Air (1) · Albuterol, Ipratropium Drug Combination (1) · Antifungal Agents (1) · Bariatric Surgery (1) · Fentanyl (1) · Formoterol Fumarate (1) · Furosemide (1)
University of California, Los Angeles (3) · Dartmouth-Hitchcock Medical Center (2) · GlaxoSmithKline (2) · Queen's University (2) · Dr. J. Alberto Neder (1) · Duke University (1) · Faculdade Evangelica do Parana (1) · Federal University of São Paulo (1) · Galaxia Empírica (1) · Helsinki University Central Hospital (1) · Henri Mondor University Hospital (1) · Hospital Clinic of Barcelona (1) · Huib A.M. Kerstjens (1) · Jean Michel Hascoet (1) · Johns Hopkins University (1)
United States (12) · Canada (5) · Netherlands (4) · Denmark (3) · France (2) · Spain (2) · Brazil (1) · Finland (1) · Germany (1) · Israel (1) · Italy (1) · Oman (1) · Switzerland (1) · United Kingdom (1)
Adam H Miller (1) · Beth Laube, PhD (1) · Chris M. Parker, MD, MSc (1) · Christian Mueller, Prof. (1) · David Price, Prof (1) · Denis E O'Donnell, MD (1) · Dharini M Bhammar, MBBS, PhD (1) · Dinesh Khanna, MD (1) · Doanld A Mahler, MD (1) · Donald A Mahler, MD (1) · Dov Heimer, M.D (1) · E. FM Wouters, MD, PhD (1) · Eric C Kleerup, MD (1)
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