731 completed, 275 unknown, 266 recruiting, 115 terminated. 400 Phase 2, 306 Not applicable, 188 Phase 1, 160 Phase 3, 64 Phase 4.
Follow Lung Diseases, Interstitial: new trials by email Literature Review of Lung Diseases, Interstitial trials Research Report on Lung Diseases, Interstitial
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Chronic COUGH Management in Interstitial Lung DisEase Non-pharmacological cough control therapy, Healthy lifestyle - Interstitial Lung Disease, Chronic Cough | Not applicable | Not yet recruiting | Aveiro University | 60 | 2027-12-20 | 2025-01-20 |
| Premedication With Dexamethasone for Preventing Interstitial Lung Disease in Patients With Breast Cancer Treated With Trastuzumab Deruxtecan Dexamethasone, antiemetic premedication, T-DXd - Breast Cancer, Interstitial Lung Disease (ILD) | Phase 3 | Not yet recruiting | Mario Negri Institute for Pharmacological Research | 244 | 2026-12-20 | 2026-10-19 |
| Long-term Extension Study to Evaluate Safety and Tolerability of Admilparant in Participants With Pulmonary Fibrosis BMS-986278 - Pulmonary Fibrosis | Phase 3 | Not yet recruiting | Bristol-Myers Squibb | 2380 | 2026-12-16 | 2026-08-14 |
| Artificial Intelligence Enhanced Remote Monitoring in Interstitial Lung Disease AIRM v1.0 AI-Enhanced Remote Monitoring - Fibrotic Interstitial Lung Disease | Not applicable | Not yet recruiting | King's College London | 120 | 2026-12-01 | 2026-09-28 |
| A Study to Assess the Efficacy and Safety of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Progressive Pulmonary Fibrosis (PPF) Treprostinil Palmitil Inhalation Powder, Placebo - Progressive Pulmonary Fibrosis, Interstitial Lung Disease | Phase 3 | Not yet recruiting | Insmed Incorporated | 800 | 2026-12-01 | 2026-09-04 |
| Autoantibody Reduction Therapy for Progressive Idiopathic Pulmonary Fibrosis Therapeutic Plasma Exchange, Rituximab, Intravenous immunoglobulin - Idiopathic Pulmonary Fibrosis | Phase 2 | Not yet recruiting | University of Alabama at Birmingham | 52 | 2026-12-01 | 2026-10-20 |
| A Trial of AGMB-447 in Participants With Idiopathic Pulmonary Fibrosis AGMB-447, Placebo - Idiopathic Pulmonary Fibrosis (IPF) | Phase 2 | Not yet recruiting | Agomab Spain S.L.U. | 120 | 2026-11-30 | 2026-10-07 |
| A Clinical Trial of Tulisokibart (MK-7240) in Participants With Pulmonary Sarcoidosis (MK-7240-016) Tulisokibart, Placebo, Background prednisone therapy - Pulmonary Sarcoidosis | Phase 2 | Not yet recruiting | Merck Sharp & Dohme LLC | 158 | 2026-11-06 | 2026-10-09 |
| Feasibility, Acceptability, and Implementability of I-IMPACT for ILD I-IMPACT, Pulmonary Rehabilitation - Interstitial Lung Disease (ILD) | Not applicable | Not yet recruiting | University Hospitals, Leicester | 50 | 2026-11-01 | 2026-08-21 |
| Evaluation of the Efficacy and Safety of Compound Betamethasone in Pulmonary Sarcoidosis Prednisone, Compound betamethasone - Sarcoidosis, Pulmonary | Phase 2 / Phase 3 | Not yet recruiting | Peking Union Medical College Hospital | 126 | 2026-11-01 | 2026-10-15 |
| Hyperpolarized Xenon MRI in Adults With Pulmonary Hypertension in Interstitial Lung Disease and Systemic Sclerosis Hyperpolarized 129 Xenon Gas - Interstitial Lung Disease, Pulmonary Hypertension | Phase 2 | Not yet recruiting | Bastiaan Driehuys | 51 | 2026-11-01 | 2026-09-15 |
| Validation of 1 Minute Sit-to Stand Test for Assessment of Breathlessness at Exertion in Individuals With Chronic Lung Disease 1MSTS - COPD (Chronic Obstructive Pulmonary Disease), Asthma (Diagnosis) | Not yet recruiting | Jacob Sandberg | 120 | 2026-11-01 | 2026-09-23 | |
| Immunomodulatory Treatment of Interstitial Lung Disease Associated With Surfactant Related Gene Variants Azithromycin 250 mg x3/week (3 tablets/week), Prednisone 10 mg/day, Hydroxychloroquine 400 mg/day - Interstitial Lung Disease | Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 30 | 2026-11-01 | 2026-09-22 |
| A Study to Assess the Safety, Tolerability and Pharmacokinetics of Repeated Doses of Inhaled CHF10073 in Participants With Idiopathic Pulmonary Fibrosis CHF10073 low dose, CHF10073 high dose, Placebo - Idiopathic Pulmonary Fibrosis | Phase 1 | Not yet recruiting | Chiesi Farmaceutici S.p.A. | 18 | 2026-11-01 | 2026-10-21 |
| A Study of BMS-986553 in Participants With Refractory Autoimmune Diseases BMS-986553 - Systemic Lupus Erythematosus, Sjögren's Disease | Phase 1 | Not yet recruiting | Bristol-Myers Squibb | 60 | 2026-10-30 | 2026-10-14 |
| An Efficacy Study of XTMAB-16 in Patients With Pulmonary Sarcoidosis With or Without Extrapulmonary Manifestations XTMAB-16, Placebo - Pulmonary Sarcoidosis | Phase 2 | Not yet recruiting | Xentria, Inc. | 182 | 2026-10-30 | 2026-10-21 |
| A Single-Arm,Multicenter Phase, Phase II Clinical Trial of Adebrelimab Combined With Trametinib in the Treatment of Refractory Recurrent Langerhans Cell Histiocytosis in Children and Adolescents treated group - Histiocytosis,Langerhans-Cell | Phase 1 / Phase 2 | Enrolling by invitation | Second Affiliated Hospital of Wenzhou Medical University | 2 | 2026-10-20 | 2026-10-22 |
| Study Evaluating 68GA-FAPI-46 PET/CT in Patients With Interstitial Lung Disease ⁶⁸Ga-FAPI-46, PET/CT - Interstitial Lung Disease | Phase 1 | Not yet recruiting | Mayo Clinic | 10 | 2026-10-16 | 2026-09-18 |
| Combined Growth Differentiation Factor-15 (GDF-15) and Lung Ultrasound for ILD Screening in Rheumatoid Arthritis and Systemic Sclerosis Lung ultrasound, GDF-15 level (ELISA), CT scan - Rheumatoid Arthritis (RA), Systemic Sclerosis (SSc) | Not yet recruiting | Assiut University | 110 | 2026-10-15 | 2026-09-25 | |
| A Randomized, Double-Blind, Placebo-Controlled Trial of Fufei Huazhuo Tongluo Formula Combined With Standardized Medicine in Patients With Anti-Synthetase Syndrome-Associated Interstitial Lung Disease FuFei HuaZhuo TongLuo Granule, Placebo granule - Anti-Synthetase Syndrome, Interstitial Lung Disease (ILD) | Not applicable | Not yet recruiting | First People's Hospital of Hangzhou | 54 | 2026-10-10 | 2026-09-23 |
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Idiopathic Pulmonary Fibrosis (569) · Pulmonary Fibrosis (333) · Pulmonary Disease, Chronic Obstructive (130) · Granulomatosis with Polyangiitis (104) · Histiocytosis, Langerhans-Cell (80) · Lung Diseases (73) · Hypertension, Pulmonary (68) · Sarcoidosis (68) · Sarcoidosis, Pulmonary (66) · Microscopic Polyangiitis (63) · Scleroderma, Systemic (53) · Arthritis, Rheumatoid (48) · Lung Neoplasms (48) · Asthma (46)
Respiratory Tract Diseases (1612) · Lung Diseases (1557) · Pathological Conditions, Signs and Symptoms (574) · Pathologic Processes (530) · Pulmonary Fibrosis (488) · Immune System Diseases (360) · Fibrosis (317) · Skin and Connective Tissue Diseases (256) · Hemic and Lymphatic Diseases (236) · Lymphatic Diseases (215) · Cardiovascular Diseases (211) · Skin Diseases (202) · Vascular Diseases (196) · Hypersensitivity (179)
pirfenidone (66) · nintedanib (65) · Rituximab (36) · Cyclophosphamide (29) · Prednisone (28) · Blood Specimen Collection (27) · Mycophenolic Acid (19) · Prednisolone (15) · Methotrexate (14) · Azathioprine (13) · Glucocorticoids (13) · Standard of Care (13) · Exercise (12) · treprostinil (12) · Biopsy (11)
Boehringer Ingelheim (67) · Assistance Publique - Hôpitaux de Paris (36) · Assiut University (19) · Hoffmann-La Roche (19) · National Heart, Lung, and Blood Institute (NHLBI) (18) · National Cancer Institute (NCI) (15) · Royal Brompton & Harefield NHS Foundation Trust (15) · National Institute of Allergy and Infectious Diseases (NIAID) (14) · National Jewish Health (14) · Peking Union Medical College Hospital (14) · Duke University (13) · GlaxoSmithKline (13) · Bristol-Myers Squibb (12) · Novartis Pharmaceuticals (12) · University of Pennsylvania (12)
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Peter A Merkel, MD, MPH (8) · Peter A. Merkel, MD, MPH (8) · Ganesh Raghu, MD (7) · Imre Noth, MD (5) · Kevin F Gibson, MD (5) · Fernando Martinez, MD (4) · Jeff Swigris, DO, MS (4)
PMID 35688625, PMID 28388260, PMID 31401903, PMID 37391667, PMID 33902584, PMID 26835133, PMID 31047956, PMID 33434107, PMID 36884302, PMID 25890798, PMID 26111071, PMID 26968970, PMID 27708114, PMID 30072107, PMID 30116539, PMID 30472023, PMID 31153107, PMID 31401786, PMID 31513482, PMID 31914963, PMID 32106306, PMID 32217654, PMID 33164993, PMID 37216396, PMID 37731389, PMID 41345848, PMID 15049016, PMID 16790698, PMID 17717203, PMID 17901414, PMID 18641099, PMID 19892673, PMID 21571362, PMID 23589673, PMID 24177001, PMID 24834811, PMID 24836310, PMID 25452309, PMID 25770676, PMID 26083430, PMID 26400368, PMID 27672117, PMID 28039616, PMID 28526798, PMID 28544580, PMID 28657784, PMID 28883090, PMID 28993537, PMID 29099620, PMID 29150411
2023 (22), 2025 (14), U10CA180886 (14), 2015 (13), 2016 (7), 2018 (7), U54AR057319 (7), 2017 (6), 2019 (6), 2009 (4), 2014 (3), R01HL126771 (3), U10HL080413 (3), R01AG006244 (2), R01HL097163 (2)