66 completed, 10 unknown, 4 terminated, 2 not yet recruiting. 24 Phase 4, 17 Phase 3, 16 Not applicable, 14 Phase 2, 6 Phase 1.
Follow Ipratropium: new trials by email Literature Review of Ipratropium trials Research Report on Ipratropium
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Patients Presenting to the Emergency Department With Acute Exacerbation of COPD (ECOPD) Revefenacin, formoterol fumarate, Placebo (Sterile Normal Saline) - COPD Exacerbation | Phase 4 | Not yet recruiting | University of Tennessee Graduate School of Medicine | 280 | 2026-11-12 | 2026-10-19 |
| Effect of Ipratropium Bromide on EILO Ipratropium Bromide, Normal Saline (Placebo) - Exercise-Induced Laryngeal Obstruction, Dyspnea During Activity | Phase 2 | Not yet recruiting | Cook Children's Health Care System | 50 | 2026-06-01 | 2026-05-05 |
| A Combination of an Inhaled Budesonide and Ipratropium in Patients at Risk of Developing ARDS combined standard aerosolized doses of budesonide (0.5 mg/2 mL) every 12 hours and ipratropium bromide (500/2 mL) every eight hours for up to five days, Placebo - ARDS, Prevention and Control | Phase 1 / Phase 2 | Completed | Damanhour University | 119 | 2024-05-01 | 2025-02-06 |
| A RCT to Compare the Effectiveness of Nebulized Anticholinergics for Cough Suppression During Flexible Bronchoscopy Glycopyrronium, Ipratropium, Saline - Subjects Undergoing Flexible Bronchoscopy | Phase 2 / Phase 3 | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 1050 | 2024-04-24 | 2024-04-22 |
| Role of Parasympathetic Activity in Mild to Severe Asthma With Fixed Airway Obstruction (PARASMA Study) Salbutamol, Ipratropium Bromide, Salbutamol plus Ipratropium Bromide - Asthma, Airway Obstruction | Not applicable | Unknown | Hat Yai Medical Education Center | 60 | 2024-02-17 | 2024-02-20 |
| Treating Respiratory Emergencies in Children Study Ipratropium Bromide - Asthma in Children | Phase 2 | Completed | Oregon Health and Science University | 44 | 2024-01-19 | 2026-04-24 |
| A Comparative Study of Adding Ipratropium to Salbutamol for the Treatment of Asthma Attack in Children Salbutamol (Ventolin®), salbutamol + ipratropium bromide nebules - Asthma Exacerbation, Children | Phase 4 | Completed | Children's Hospital and Institute of Child Health, Multan | 60 | 2024-01-01 | 2025-04-09 |
| Comparison of Ipratropium / Levosalbutamol Fixed Dose Combination and Ipratropium and Levosalbutamol Free Dose Combination in pMDI Form in Stable Chronic Obstructive Pulmonary Disease (COPD) Patients Ipratropium / Levosalbutamol Fixed Dose Combination, Ipratropium + Levosalbutamol Free Dose Combination - COPD | Phase 3 | Unknown | Neutec Ar-Ge San ve Tic A.Ş | 74 | 2023-09-28 | 2023-10-03 |
| Comparison of Ipratropium / Levosalbutamol Fixed Dose Combination and Ipratropium and Levosalbutamol Free Dose Combination Nebuliser Solutions in Stable Chronic Obstructive Pulmonary Disease (COPD) Patients Ipratropium / Levosalbutamol Fixed Dose Combination, Ipratropium + Levosalbutamol Free Dose Combination - COPD | Phase 3 | Unknown | Neutec Ar-Ge San ve Tic A.Ş | 74 | 2023-08-25 | 2023-09-05 |
| Neural Respiratory Drive of Patients With Chronic Obstructive Pulmonary Disease compound ipratropium bromide solution (3mg salbutamol and 500μg ipratropium, Boehringer Ingelheim Limited, Germany) - Chronic Obstructive Pulmonary Disease | Not applicable | Completed | The First Affiliated Hospital of Guangzhou Medical University | 44 | 2023-01-01 | 2025-05-07 |
| Bronchodilators on the Exercise Capacity of Bronchiectasis Patients Bronchodilator (Ipratropium and Fenoterol), Placebo - Bronchiectasis Adult | Not applicable | Unknown | University of Sao Paulo General Hospital | 40 | 2022-04-14 | 2023-12-11 |
| Acute Bronchodilator Effects of Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination vs Salbutamol 100 mcg Inhaler Plus Ipratropium 20 mcg Inhalation Aerosol Free Combination in Patients With Stable COPD Ipratropium/Levosalbutamol 20/50 mcg Fixed Dose Combination (2 inhalations) via pMDI, Salbutamol 100 mcg Inhaler (2 inhalations) + Ipratropium 20 mcg Inhalation Aerosol (2 inhalations) Free Combination via MDI - Chronic Obstructive Pulmonary Disease | Phase 3 | Withdrawn | Neutec Ar-Ge San ve Tic A.Ş | 2021-09-03 | 2021-09-13 | |
| Revefenacin in Acute Respiratory Insufficiency in COPD Revefenacin Inhalation Solution [Yupelri], Ipratropium Bromide - COPD, Acute Respiratory Failure | Phase 2 | Completed | University of California, Los Angeles | 21 | 2020-11-01 | 2026-10-14 |
| Ipratropium Bromide Spray as Treatment for Sialorrhea in Children Ipratropium bromide, Placebo - Sialorrhea | Phase 2 | Unknown | London Health Sciences Centre | 30 | 2019-01-01 | 2018-11-21 |
| Non-invasive Ventilation vs. Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma BiPAP, CPAP, Ipratropium - Asthma Acute, Asthma in Children | Not applicable | Unknown | University of British Columbia | 100 | 2018-06-01 | 2018-05-02 |
| Cryobiopsy Study to Assess Drug Distribution in Subjects With Suspected Interstitial Lung Disease Ipratropium Bromide, Flexible Bronchoscopy/Biopsy - Lung Diseases, Interstitial | Completed | GlaxoSmithKline | 8 | 2017-11-21 | 2019-01-29 | |
| Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD) Nebulizers, Dry Powder Inhaler, Brovana - COPD, COPD Exacerbation | Phase 4 | Terminated | Wake Forest University Health Sciences | 40 | 2017-10-03 | 2021-06-22 |
| Glittre ADL-test: Responsiveness to Acute Bronchodilation in Chronic Obstructive Pulmonary Disease (COPD) Bronchodilators, Placebos - Chronic Obstructive Pulmonary Disease | Not applicable | Unknown | Laval University | 34 | 2017-04-13 | 2018-07-06 |
| Influence of Mechanical Ventilation Modes on the Efficacy of Nebulized Bronchodilator salbutamol sulfate and ipratropium bromide, Mesh nebulization - COPD, Asthma | Not applicable | Unknown | Universidade Federal do Rio Grande do Norte | 10 | 2017-04-10 | 2019-05-21 |
| Acute Bronchodilator Effect of Inhaled Albuterol Sulfate and Ipratropium Bromide in Patients With Stable COPD Albuterol Sulfate and Ipratropium Bromide, Albuterol Sulfate - COPD | Phase 1 | Completed | Pneuma Respiratory, Inc | 46 | 2016-12-27 | 2018-03-29 |
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Pulmonary Disease, Chronic Obstructive (46) · Asthma (16) · Dyspnea (3) · Motor Activity (3) · Sialorrhea (3) · Common Cold (2) · Emergencies (2) · Lung Diseases, Obstructive (2) · Acute Lung Injury (1) · Airway Obstruction (1) · Airway Remodeling (1) · Asthma, Exercise-Induced (1) · Autonomic Nervous System Diseases (1) · Bronchiectasis (1) · Bronchiolitis Obliterans Syndrome (1)
Boehringer Ingelheim (19) · GlaxoSmithKline (8) · Neutec Ar-Ge San ve Tic A.Ş (3) · Laval University (2) · AstraZeneca (1) · Beaumont Hospital (1) · Centre for Addiction and Mental Health (1) · Children's Hospital and Institute of Child Health, Multan (1) · Children's Hospital of Philadelphia (1) · Columbia University (1) · Cook Children's Health Care System (1) · Damanhour University (1) · Dey (1) · Fahim Khorfan, MD (1) · Hat Yai Medical Education Center (1)
United States (25) · United Kingdom (8) · Canada (6) · China (4) · Brazil (2) · Netherlands (2) · Turkey (Türkiye) (2) · Argentina (1) · Australia (1) · Belgium (1) · Egypt (1) · France (1) · India (1) · Ireland (1) · Lithuania (1)
Ahmet Tutuncu, M.D., Ph.D. (1) · Alan James, MBBS (1) · Alvin Ing, MBBS (1) · Ann M. Spungen, EdD (1) · Bryan D. Upham, M.D. (1) · Celso RF Carvalho, PhD (1) · Chen Xin, Doctor (1) · Chris Steinfort, MBBS (1) · Christoph Ellenberger, MD (1) · Colin Reisner, M.D. (1) · Cynthia J Mollen, M.D. (1)
PMID 11113831, PMID 11825832, PMID 17890476, PMID 17989152, PMID 19232039, PMID 19496252, PMID 19758522, PMID 21960699, PMID 22509905, PMID 23658479, PMID 25197005, PMID 26024688, PMID 27486205, PMID 29506504, PMID 29631575, PMID 30166326, PMID 33124005, PMID 35546672, PMID 36699648, PMID 40720815, PMID 41943480
2015 (1), UL1TR001412 (1)