54 completed, 21 unknown, 6 recruiting, 5 terminated. 44 Phase 4, 24 Not applicable, 11 Phase 2, 8 Phase 3, 3 Early Phase 1.
Follow Tetracycline: new trials by email Literature Review of Tetracycline trials Research Report on Tetracycline
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy And Safety of Bismuth-Tetracycline-Rabeprazole Triple For First-Line Eradication of Helicobacter Pylori Infection Bismuth, Bismuth quadruple therapy - Helicobatcer Pylori, First-Line Eradication | Not applicable | Not yet recruiting | Chih-An Shih, MD | 300 | 2026-09-01 | 2026-08-26 |
| Pylori Duo for Adjunctive Treatment and Prevention of Recurrence of Helicobacter Pylori Infection Omeprazole, Pylera (Bismuth subcitrate potassium, metronidazole, tetracycline) given in combination with omeprazole, Pylori Duo - Helicobacter Pylori Infection, Dyspepsia | Not applicable | Not yet recruiting | Gala Servicios Clinicos S.L. | 140 | 2026-08-31 | 2026-07-27 |
| Injection Sclerotherapy With Bleomycin VS Doxycycline in Patients With Lymphatic Malformations Bleomycin, doxycycline (tetracycline) - Lymphatic Abnormality | Phase 2 | Not yet recruiting | Basharat Hussain | 92 | 2026-01-26 | 2026-01-06 |
| Effect of Intraoperative Tetracycline on Postoperative Pain After Mandibular Molar Extraction Tetracycline, No Intrasocket Medicament - Postoperative Pain, Mandibular Molar Extraction | Phase 4 | Active not recruiting | CMH Lahore Medical College and Institute of Dentistry | 74 | 2026-01-10 | 2026-09-14 |
| Saccharomyces Boulardii Combined With Bismuth Quadruple Therapy for Helicobacter Pylori Rescue Treatment Bismuth, Esomeprazole, Tetracycline - Gastritis, Dyspepsia | Phase 4 | Recruiting | Yongquan Shi | 1248 | 2025-10-28 | 2025-12-02 |
| Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy and Bismuth Quadruple Therapy vonoprazan, tripotassium dicitrate bismuthate, amoxicilline, rabeprazole, tripotassium dicitrate bismuthate, tetracycline, metronidazole - Helicobacter Pylori Infection | Not applicable | Recruiting | Kaohsiung Medical University | 552 | 2025-10-21 | 2026-01-22 |
| Prospective Study of Frontline Antibiotics Therapy in the Treatment of Early-stage HP-negative Gastric MALT Lymphoma Esomeprazole, Bismuth tripotassium dicitrate, Tetracycline, and Metronidazole - MALT Lymphoma of Stomach | Phase 2 | Not yet recruiting | National Taiwan University Hospital | 40 | 2025-09-01 | 2025-08-27 |
| Tegoprazan-Based Therapies for H. Pylori Eradication: A Randomized Controlled Trial Tegoprazan, Amoxicillin, Tetracycline - Helicobacter Pylori Eradication, Adverse Reaction | Not applicable | Completed | Zhongshan Hospital (Xiamen), Fudan University | 640 | 2025-06-10 | 2026-05-19 |
| Efficacy Comparison of Vonoprazan Combined With Different Antibiotics in Dual Therapy for Helicobacter Pylori Eradication: A Prospective, Randomized Controlled Clinical Trial Vonoprazan, Tetracycline 500mg tid, Minocycline - Gastritis, Indigestion, Helicobacter Pylori Infection, Gastric Cancer, Peptic Ulcer | Phase 4 | Recruiting | Yongquan Shi | 400 | 2025-04-01 | 2025-08-14 |
| Weekly Isotretinoin vs Tetracycline for Moderate Acne Isotretinoin, Tetracycline - Acne Vulgaris | Early Phase 1 | Recruiting | Medical University of South Carolina | 50 | 2025-02-01 | 2026-05-18 |
| Triple Versus Quadruple Therapy for the Eradication of Helicobacter Pylori Vonoprazan-Amoxicillin-Tetracycline-Bismuth quadruple regimen for 14 days, Vonoprazan-Amoxicillin-Tetracycline triple regimen for 14 days, Vonoprazan-Amoxicillin-Tetracycline triple regimen for 7 days - Helicobacter Pylori Infection | Not applicable | Unknown | Shandong University | 375 | 2024-11-27 | 2024-12-03 |
| Optimization of Minocycline for Helicobacter Pylori Rescue Treatment Vonoprazan, Bismuth Potassium Citrate, Tetracycline,Metronidazole - Helicobacter Pylori Infection | Phase 4 | Completed | Shanghai Jiao Tong University School of Medicine | 480 | 2024-08-21 | 2026-03-25 |
| Optimal Duration of Bismuth Quadruple Therapy for Helicobacter Pylori Eradication in Females As Compared with Males Drug: Bismuth Subcitrate 120 MG Oral Tablet, Esomeprazole 40mg, Metronidazole 250 MG - Helicobacter Pylori Infection, Sex | Phase 4 | Enrolling by invitation | National Cheng-Kung University Hospital | 661 | 2024-07-09 | 2024-11-07 |
| Efficacy and Safety of Bismuth Quadruple Therapy Containing Cefuroxime and Tetracycline as First-line Therapy for Eradicating Helicobacter Pylori in Patients Allergic to Penicillin 14-day bismuth quadruple regimen containing cefuroxime and tetracycline, 14-day bismuth quadruple regimen containing cefuroxime and levofloxacin - Helicobacter Pylori Infection | Phase 4 | Unknown | Qilu Hospital of Shandong University | 248 | 2024-04-01 | 2024-04-08 |
| Effect of Tetracycline Socked Pack on Acceleration of Healing During Marsupialization Tetracyclin - Ameloblastoma | Not applicable | Completed | Minia University | 14 | 2024-02-10 | 2025-01-06 |
| Efficacy of 7-day Versus 14-day Bismuth Quadruple Therapy for the Eradication of Helicobacter Pylori（SHARE2302) 7days bismuth quadruple, 14 days bismuth quadruple - Helicobacter Pylori Infection | Not applicable | Unknown | Shandong University | 254 | 2023-09-02 | 2024-01-11 |
| Doxycycline for Helicobacter Pylori Rescue Treatment Esomeprazole, Bismuth Potassium Citrate, Tetracycline - Helicobacter Pylori Infection | Phase 4 | Recruiting | Shanghai Jiao Tong University School of Medicine | 368 | 2023-06-20 | 2024-12-30 |
| Helicobacter Rescue Therapy With Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy Vonoprazan, amoxicillin, Bismuth - Gastritis Dyspepsia Helicobacter Pylori Infection Gastric Cancer Peptic Ulcer | Phase 4 | Completed | Yongquan Shi | 688 | 2023-06-06 | 2025-07-03 |
| Rescue Therapy for Helicobacter Pylori Infection Vonoprazan, Bismuth Potassium Citrate, Tetracycline - Helicobacter Pylori Infection | Phase 4 | Completed | Shanghai Jiao Tong University School of Medicine | 360 | 2023-05-16 | 2025-09-15 |
| Bismuth Quadruple Therapy in Helicobacter Pylori Rescue Therapy of Different Tetracycline Doses and Frequencies. Tetracycline 500mg tid, Tetracycline 500mg qid - Helicobacter Pylori Infection | Phase 4 | Unknown | Shandong University | 260 | 2023-03-12 | 2023-04-07 |
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cyclopia sequence (5) · Dyspepsia (4) · Gastritis (4) · Helicobacter Infections (4) · Stomach Neoplasms (4) · Lymphoma, B-Cell, Marginal Zone (3) · Peptic Ulcer (3) · Cognitive Dysfunction (2) · Fatigue (2) · Lymphoma (2) · Osteoporosis (2) · Vaginosis, Bacterial (2) · Acne Vulgaris (1) · Agnosia (1) · Alzheimer Disease (1)
Shandong University (14) · Shanghai Jiao Tong University School of Medicine (9) · Kaohsiung Veterans General Hospital. (6) · National Taiwan University Hospital (6) · Seoul National University Bundang Hospital (3) · Shanghai Zhongshan Hospital (3) · Yongquan Shi (3) · Johns Hopkins University (2) · Kaohsiung Medical University (2) · National Cheng-Kung University Hospital (2) · Xijing Hospital of Digestive Diseases (2) · Yale University (2) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (1) · Alliance for Clinical Trials in Oncology (1) · Amgen (1)
China (33) · Taiwan (18) · United States (17) · South Korea (5) · Italy (3) · Brazil (2) · Spain (2) · Switzerland (2) · United Kingdom (2) · Bangladesh (1) · Canada (1) · Chile (1) · Egypt (1) · Ethiopia (1) · Hong Kong (1)
Ping-I Hsu, Bachelor (6) · Xiuli Zuo, MD,PhD (5) · Jyh-Chin Yang, M.D.Ph.D. (3) · Jyh-Ming Liou, MD, PhD (2) · Li Yanqing, MD, PhD (2) · Taotao Liu, MD (2) · Xiuli Zuo, PhD,MD (2) · Yanqing Li, Ph.D (2) · Alex Richmond, MD, MSCR (1) · Aminah Jatoi, MD (1) · Asad A Chatha, BDS, FCPS (1) · Asiya Ferdous, MBBS (1) · Brian D Ross (1)
PMID 27707777, PMID 28456631, PMID 32348007, PMID 34836916, PMID 15371921, PMID 15691312, PMID 25741163, PMID 29914954, PMID 15276398, PMID 15840453, PMID 16534049, PMID 17170018, PMID 18543329, PMID 19588358, PMID 19901217, PMID 20820817, PMID 21051704, PMID 21188333, PMID 21345487, PMID 21762268, PMID 21900636, PMID 22159169, PMID 22530208, PMID 22876748, PMID 23158886, PMID 23376004, PMID 24050512, PMID 24295850, PMID 25377444, PMID 25491305, PMID 25882778, PMID 27144617, PMID 27460100, PMID 27687850, PMID 27769562, PMID 28329131, PMID 28807915, PMID 28957341, PMID 29024120, PMID 29609070, PMID 30038469, PMID 32163613, PMID 32428369, PMID 33004546, PMID 33619183, PMID 33637332, PMID 33691344, PMID 34397042, PMID 34919861, PMID 35956057
P30CA016672 (1), T32DA007238 (1), U01AI068636 (1), U10CA032102 (1), U10EY023939 (1)