11 completed, 2 not yet recruiting. 4 Phase 2, 4 Phase 3, 2 Not applicable, 2 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 4 |
| Phase 3 | 4 | Completed 3, Not yet recruiting 1 |
| Not applicable | 2 | Completed 2 |
| Phase 1 | 2 | Completed 2 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Z 338: new trials by email Literature Review of Z 338 trials Research Report on Z 338
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Acotiamide and Itopride for the Management of Indigestion Acotiamide, itopride - Functioanl Dyspepsia, Post Prandial Distress Syndrome | Phase 4 | Not yet recruiting | Aga Khan University | 368 | 2026-04-01 | 2026-03-06 |
| Acotiamide vs Itopride in Postprandial Distress Syndrome Acotiamide - Postprandial Distress Syndrome | Phase 3 | Not yet recruiting | Getz Pharma | 152 | 2025-10-30 | 2025-09-23 |
| Helicobacter Pylori Eradication in Functional Dyspepsia Clarithromycin 500mg, Amoxicillin 1000 MG, Pantoprazole 40mg - Dyspepsia, Helicobacter Pylori Infection | Not applicable | Completed | Sir Ganga Ram Hospital | 202 | 2017-09-01 | 2021-01-14 |
| Effect of Acotiamide on Gastric Motility and Satiation in Healthy Volunteers Acotiamide, Placebo Oral Tablet - Healthy | Not applicable | Completed | Universitaire Ziekenhuizen KU Leuven | 20 | 2017-04-01 | 2018-01-18 |
| Phase III, Long-term, Open-label Safety Study of Z-338 Z-338 - Dyspepsia | Phase 3 | Completed | Zeria Pharmaceutical | 207 | 2014-03-01 | 2017-06-28 |
| Effect of Food Intake on Pharmacokinetic Profiles of Z-338 Z-338 - Healthy | Phase 1 | Completed | Astellas Pharma Inc | 30 | 2009-03-01 | 2009-07-20 |
| A Study to Evaluate the Effect of Repeat Oral Doses of YM443 on Cardiac Repolarization in Healthy Adults YM443, Placebo, Moxifloxacin - Functional Dyspepsia | Phase 1 | Completed | Astellas Pharma Inc | 80 | 2009-02-01 | 2014-03-24 |
| To Verify the Efficacy of Z-338 in Subjects With Functional Dyspepsia Z-338, Placebo - Functional Dyspepsia | Phase 3 | Completed | Zeria Pharmaceutical | 820 | 2008-09-01 | 2010-11-23 |
| A Long-term, Open-label, Uncontrolled Trial of YM443 (Z-338) in Patients With Functional Dyspepsia YM443 - Dyspepsia, Functional Dyspepsia | Phase 3 | Completed | Astellas Pharma Inc | 412 | 2008-08-01 | 2014-10-29 |
| The Effect of Z-338 in Subjects With Functional Dyspepsia Z-338 - Functioanl Dyspepsia | Phase 2 | Completed | Zeria Pharmaceutical | 40 | 2007-04-01 | 2010-11-23 |
| To Evaluate the Efficacy and Safety in Subjects With Functional Dyspepsia Z-338 - Functional Dyspepsia | Phase 2 | Completed | Zeria Pharmaceutical | 282 | 2006-04-01 | 2015-05-28 |
| To Evaluate the Efficacy of Z-338 in Subjects With Functional Dyspepsia Z-338 - Functional Dyspepsia | Phase 2 | Completed | Zeria Pharmaceutical | 440 | 2006-04-01 | 2009-01-14 |
| The Effects of Z-338 in Subjects With and Without Functional Dyspepsia Z-338 - Dyspepsia | Phase 2 | Completed | Zeria Pharmaceutical | 52 | 2006-02-01 | 2009-01-14 |
Dyspepsia (4) · Signs and Symptoms, Digestive (1)
Zeria Pharmaceutical (6) · Astellas Pharma Inc (3) · Aga Khan University (1) · Getz Pharma (1) · Sir Ganga Ram Hospital (1) · Universitaire Ziekenhuizen KU Leuven (1)
Japan (5) · Belgium (3) · Australia (1) · Bulgaria (1) · India (1) · Latvia (1) · Lithuania (1) · Romania (1) · Russia (1) · Slovakia (1) · Sweden (1) · Ukraine (1) · United Kingdom (1) · United States (1)
Jan Tack, PhD, MD (2) · Michio Hongo, Professor (2) · Gerald Holtmann, Professor (1) · Jan Tack, MD, PhD (1) · Ken Haruma, MD, PhD (1) · Prof. Dr. Muahmmad Umar, MBBS, FCPS, FACG, AGAF, FRCP (1) · Shahab Abid, MBBS, FCPS, FRCP, PhD (1)
PMID 22157329, PMID 29315999, PMID 30663175, PMID 34708338
2025 (1)