76 completed. 76 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 76 | Completed 76 |
Follow Dyskinesias: new trials by email Literature Review of Dyskinesias trials Research Report on Dyskinesias
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Dapagliflozin Administration on the Apoptosis Levels of Patients With Acute Myocardial Infarction Forxiga® 10 mg Film-Coated Tablet, manufactured by AstraZeneca Pharmaceuticals LP, USA for AstraZeneca Pharmaceuticals Co. Ltd., China imported by PT AstraZeneca Indonesia, Indonesia - Acute Myocardial Infarction (AMI), STEMI - ST Elevation Myocardial Infarction (MI) | Phase 4 | Completed | Yoga Yudhistira | 40 | 2024-09-21 | 2025-02-27 |
| Real World Effectiveness and Safety of Deutetrabenazine in Adult Chinese Participants With Huntington's Disease (HD) Chorea in China Deutetrabenazine - Huntington's Disease, Chorea | Phase 4 | Completed | Teva Branded Pharmaceutical Products R&D LLC | 50 | 2024-02-02 | 2026-08-27 |
| Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar Disorder Sublingual film containing Igalmi - Bipolar Disorder, Schizophrenia | Phase 4 | Completed | BioXcel Therapeutics Inc | 29 | 2023-10-02 | 2026-08-11 |
| Study of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tardive Dyskinesia Valbenazine - Schizophrenia, Schizoaffective Disorder | Phase 4 | Completed | Neurocrine Biosciences | 59 | 2023-05-09 | 2026-01-16 |
| Istradefylline Effect Protocol on Parkinson's Disease Tremor Istradefylline Pill - Parkinson Disease, Tremor | Phase 4 | Completed | Georgetown University | 27 | 2023-01-20 | 2025-03-13 |
| Clinical Study of Ingrezza (Valbenazine) for the Treatment of Cervical Dystonia Ingrezza Pill - Cervical Dystonia | Phase 4 | Completed | The Orthopedic Foundation | 20 | 2021-10-19 | 2023-10-06 |
| Emergence Agitation After Nasal Surgery: a Randomized Controlled Comparison Between Melatonin and Mirtazapine Mirtazapine, Melatonin, Placebo - Agitation | Phase 4 | Completed | Ain Shams University | 165 | 2021-06-15 | 2022-04-15 |
| Mixed Methods Investigation of Chronic Facial Paralysis in Individuals With Synkinesis Neuromuscular Retraining Therapy (4 months), Chemodenervation (4 months), Neuromuscular Retraining + Chemodenervation - Synkinesis | Phase 4 | Completed | University of Wisconsin, Madison | 15 | 2019-10-24 | 2022-09-29 |
| Persistence of Effect and Safety of Valbenazine for the Treatment of Tardive Dyskinesia Valbenazine, Placebo oral capsule - Tardive Dyskinesia (TD) | Phase 4 | Completed | Neurocrine Biosciences | 135 | 2019-03-18 | 2021-04-20 |
| C-Trelin Orally Disintegrated(OD) Tablet 5mg in Ataxia Due to Spinocerebellar Degeneration C-Trelin OD Tab(5mg Taltirelin Hydrate), Placebo - Spinocerebellar Degeneration | Phase 4 | Completed | HLB Pharmaceutical Co., Ltd. | 160 | 2019-03-04 | 2023-07-24 |
| Dexmedetomidine Combined With Hydromorphone in Tonsillectomy and Adenoidectomy Dexmedetomidine 0.5μg／kg, Dexmedetomidine 1μg／kg - Agitated; State, Acute Reaction to Stress | Phase 4 | Completed | Eye & ENT Hospital of Fudan University | 130 | 2019-01-04 | 2021-06-22 |
| The Potential for Clinical Dependence and Withdrawal Symptoms Associated With Valbenazine Valbenazine, Placebo oral capsule - Tardive Dyskinesia (TD) | Phase 4 | Completed | Neurocrine Biosciences | 89 | 2018-09-14 | 2020-06-04 |
| TREC-Lebanon: A Trial for Rapid Tranquilisation for Agitated Patients in the Emergency Setting Haloperidol + Promethazine + Chlorpromazine, Haloperidol + Promethazine - Psychiatric Emergency, Aggression | Phase 4 | Completed | Joseph Dib | 100 | 2018-08-28 | 2022-06-14 |
| Does Low Flow Anesthesia Reduce Postanaesthetic Emergence Agitation? Analgesics, Antiemetics - Agitated; State, Acute Reaction to Stress | Phase 4 | Completed | Sakarya University | 60 | 2018-06-01 | 2020-03-18 |
| Gabapentin as Preanesthetic Medication to Fast Procedures in Pediatric´s Oncology Placebo Group, GABA 15mg/kg Group, GABA 30mg/kg Group - Pain, Postoperative, Agitation States as Acute Reaction to Exceptional Stress | Phase 4 | Completed | Hospital Infantil Albert Sabin | 135 | 2017-07-01 | 2018-09-27 |
| The Effect of Intraoperative Magnesium Sulfate Infusion on the Occurrence of Emergence Agitation Magnesium Sulfate, Normal saline - Agitation,Psychomotor | Phase 4 | Completed | Seoul National University Bundang Hospital | 92 | 2017-03-19 | 2023-09-11 |
| Response of Individuals With Ataxia-Telangiectasia to Metformin and Pioglitazone Metformin, Pioglitazone - Ataxia-Telangiectasia | Phase 4 | Completed | NHS Tayside | 27 | 2016-09-29 | 2017-12-04 |
| Phase IV to Evaluate the Safety of Self-administered ADASUVE® in Agitated Patients Outside the Hospital Setting Staccato® Delivery System Loxapine (ADASUVE®) - Agitation | Phase 4 | Completed | Ferrer Internacional S.A. | 323 | 2016-09-08 | 2020-11-04 |
| Comparison of Ketamine-propofol Combinations Ketamine-propofol mixture - Agitation, Postoperative Pain | Phase 4 | Completed | Cukurova University | 75 | 2016-07-01 | 2017-04-20 |
| OnabotulinumtoxinA in the Management of Psychogenic Dystonia CBT - Torticollis, Dystonia | Phase 4 | Completed | University of Cincinnati | 18 | 2016-01-15 | 2018-11-30 |
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Psychomotor Agitation (33) · Torticollis (10) · Psychotic Disorders (9) · Parkinson Disease (8) · Alzheimer Disease (7) · Tardive Dyskinesia (7) · Dementia (6) · Dystonia (6) · Schizophrenia (6) · Tremor (5) · Aggression (4) · Bipolar Disorder (3) · Essential Tremor (3) · Huntington Disease (3)
Neurologic Manifestations (74) · Pathological Conditions, Signs and Symptoms (73) · Signs and Symptoms (72) · Nervous System Diseases (68) · Central Nervous System Diseases (36) · Neurobehavioral Manifestations (34) · Aberrant Motor Behavior in Dementia (33) · Behavioral Symptoms (33) · Psychomotor Disorders (33) · Behavior (32) · Brain Diseases (26) · Mental Disorders (25) · Movement Disorders (25) · Neurodegenerative Diseases (23)
Botulinum Toxins, Type A (9) · Dexmedetomidine (6) · Risperidone (6) · Olanzapine (5) · Quetiapine Fumarate (5) · abobotulinumtoxinA (4) · incobotulinumtoxinA (4) · valbenazine (4) · Amantadine (3) · Haloperidol (3) · Memantine (3) · Saline Solution (3) · Clonidine (2) · Escitalopram (2) · Levetiracetam (2)
Neurocrine Biosciences (3) · Allergan (2) · Merz Pharmaceuticals GmbH (2) · New York State Psychiatric Institute (2) · Abarbanel Mental Health Center (1) · Ain Shams University (1) · Ajou University School of Medicine (1) · Assistance Publique - Hôpitaux de Paris (1) · Beijing Pins Medical Co., Ltd (1) · BioXcel Therapeutics Inc (1) · Caroff, Stanley N., M.D. (1) · Columbia University (1) · Copenhagen University Hospital, Rigshospitalet (1) · Cukurova University (1) · East Kent Hospitals University NHS Foundation Trust (1)
United States (36) · South Korea (5) · China (4) · France (4) · Germany (3) · Puerto Rico (3) · Turkey (Türkiye) (3) · United Kingdom (3) · Austria (2) · Canada (2) · Croatia (2) · Israel (2) · Spain (2) · Taiwan (2) · Argentina (1)
Harvey S Singer, MD (2) · Adrian Leibovici MD (1) · Ahmad Yasa MD (1) · Alberto Espay, MD (1) · Alexander Storch, M (1) · Ali Fuat Erdem, Professor (1) · Andrea Snow, PhD MS BS (1) · Andreea Nissenkorn, MD (1) · Aparna Wagle Shukla, MD (1) · Barbara J Coffey, MD, MS (1) · Ben Jong,de, MD (1) · Benjamin W Friedman, MD (1) · Beom S Jeon, MD, PhD (1)
PMID 11442853, PMID 12635389, PMID 17388711, PMID 20418301, PMID 20441726, PMID 20705788, PMID 21476613, PMID 21845596, PMID 22550086, PMID 22567095, PMID 23075176, PMID 23687362, PMID 24606117, PMID 25230144, PMID 25476727, PMID 26332857, PMID 27264945, PMID 27855483, PMID 28877705, PMID 28973094, PMID 29249041, PMID 29881956, PMID 30169192, PMID 30282677, PMID 30323563, PMID 32528650, PMID 34627829, PMID 35330880
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