8 completed, 7 unknown, 2 withdrawn, 1 not yet recruiting. 18 Phase 2, 6 Phase 1, 5 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 18 | Completed 8, Unknown 7, Withdrawn 2, Not yet recruiting 1 |
| Phase 1 | 6 | Completed 3, Unknown 2, Withdrawn 1 |
| Phase 3 | 5 | Unknown 3, Completed 1, Withdrawn 1 |
Follow Drug Effect: new trials by email Literature Review of Drug Effect trials Research Report on Drug Effect
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Application of Memantine and Pioglitazone to Protect Cognitive Function After Radiotherapy Memantine Oral Tablet, Pioglitazone 15mg, Hippocampal avoidance whole-brain radiotherapy (HA-WBRT) - Radiation Disease, Cognitive Impairment | Phase 2 | Not yet recruiting | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | 67 | 2024-09-10 | 2024-09-19 |
| Different Volumes of Articaine for Inferior Alveolar Nerve Block in Irreversible Pulpitis Articaine HCl 4 % / EPINEPHrine 1:100,000 in 1.8 mL Dental Cartridge - Drug Effect, Pulpitis - Irreversible | Phase 2 | Completed | Armed Forces Institute of Dentistry, Pakistan | 78 | 2023-12-01 | 2024-10-15 |
| Dose Finding Study for Remimazolam in Children Remimazolam besylate - Drug Effect | Phase 2 | Unknown | Seoul National University Hospital | 50 | 2023-11-16 | 2023-11-22 |
| Metformin to Prevent Preterm Birth in Twin Pregnancy Metformin, Placebo oral tablet - Preterm Birth, Premature Obstetric Labor | Phase 2 / Phase 3 | Unknown | The University of Hong Kong | 790 | 2022-06-01 | 2022-06-23 |
| Efficacy and Safety of Hetrombopag in Non-severe Aplastic Anemia Hetrombopag - Aplastic Anemia, Drug Effect | Phase 2 / Phase 3 | Withdrawn | Peking Union Medical College Hospital | 2021-10-01 | 2026-06-08 | |
| Efficacy and Safety of Expanded UCMSCs On Patients With Moderate to Severe Psoriasis Umbilical cord mesenchymal stem cells - Mesenchymal Stromal Cells, Psoriasis | Phase 1 / Phase 2 | Unknown | Guangdong Provincial Hospital of Traditional Chinese Medicine | 5 | 2021-08-31 | 2021-02-09 |
| Comparison of PSORI-CM01 Formula vs Gu Ben Hua Yu Formula Combined With AD-MSCs in Psoriasis PSORI-CM01 formula, Gu Ben Hua Yu formula, adipose-derived multipotent mesenchymal stem cells - Traditional Chinese Medicine, Drug Effect | Phase 1 / Phase 2 | Unknown | Guangdong Provincial Hospital of Traditional Chinese Medicine | 16 | 2021-03-17 | 2023-08-24 |
| Avatrombopag Usage in NSAA Avatrombopag 20 MG - Aplastic Anemia, Drug Effect | Phase 2 / Phase 3 | Unknown | Peking Union Medical College Hospital | 40 | 2021-02-01 | 2021-01-28 |
| Comparison of Duloxetine Versus Pregabalin Duloxetine, Pregablin - Drug Effect | Phase 2 | Unknown | National Cancer Institute, Egypt | 70 | 2020-12-20 | 2021-01-27 |
| Efficacy and Safety of Eltrombopag + Tacrolimus in Chinese Refractory or Relapsed Aplastic Anemia Patients Tacrolimus, Placebo (for Tacrolimus) - Aplastic Anemia, Drug Effect | Phase 2 | Completed | Peking Union Medical College Hospital | 114 | 2020-07-01 | 2023-01-19 |
| Glutamine Effects in Burn Patients Dipeptiven, normal Saline - Drug Effect | Phase 2 / Phase 3 | Unknown | Menoufia University | 60 | 2020-06-01 | 2021-12-01 |
| Ketamine to Improve Recovery After Cesarean Delivery - Part 1 Ketamine - Obstetric Pain, Postpartum Depression | Phase 2 | Completed | Grace Lim, MD, MS | 8 | 2019-10-09 | 2022-12-20 |
| Evaluation of Antibacterial Effect of Allium Sativum, Calcium Hydroxide and Their Combination in Infected Mature Teeth Allium Sativum, Polymerase chain reaction - Drug Effect | Phase 2 / Phase 3 | Completed | Suez Canal University | 48 | 2019-10-08 | 2021-09-20 |
| Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment in Patients With Moderate to Severe Psoriasis Calcipotriol ointment, adipose-derived multipotent mesenchymal stem cells - Mesenchymal Stromal Cells, Psoriasis | Phase 1 / Phase 2 | Completed | Guangdong Provincial Hospital of Traditional Chinese Medicine | 8 | 2019-07-23 | 2023-08-24 |
| Evaluation of Efficacy and Safety of Subcutaneous Acetaminophen Acetaminophen - Pain, Fever | Phase 2 | Completed | Saint-Joseph University | 31 | 2018-05-17 | 2020-06-09 |
| Effects of Salvinorin A on Brain Function Salvinorin A - Drug Effect | Phase 1 / Phase 2 | Completed | Johns Hopkins University | 13 | 2017-12-14 | 2021-03-04 |
| Development of a Morphine Pharmacokinetic and Pharmacodynamic Model for the Neonatal Population Morphine - Pain, Drug Effect | Phase 1 / Phase 2 | Withdrawn | The Hospital for Sick Children | 2017-12-01 | 2020-02-25 | |
| Safety and Efficacy of Expanded Allogeneic AD-MSCs in Patients With Moderate to Severe Psoriasis adipose-derived multipotent mesenchymal stem cells - Mesenchymal Stromal Cells, Psoriasis | Phase 1 / Phase 2 | Completed | Guangdong Provincial Hospital of Traditional Chinese Medicine | 7 | 2017-09-24 | 2023-08-25 |
Drug-Related Side Effects and Adverse Reactions (4) · Psoriasis (4) · Anemia, Aplastic (3) · Pain (2) · Abnormalities, Radiation-Induced (1) · Acute Pain (1) · Breast Feeding (1) · Chronic Pain (1) · Cognitive Dysfunction (1) · Depression, Postpartum (1) · Fever (1) · Labor Pain (1) · Obstetric Labor, Premature (1) · Pregnancy Complications (1) · Premature Birth (1)
Chemically-Induced Disorders (4) · Skin Diseases (4) · Skin Diseases, Papulosquamous (4) · Skin and Connective Tissue Diseases (4) · Anemia (3) · Bone Marrow Diseases (3) · Bone Marrow Failure Disorders (3) · Hematologic Diseases (3) · Hemic and Lymphatic Diseases (3) · Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Female Urogenital Diseases and Pregnancy Complications (2) · Mental Disorders (2) · Urogenital Diseases (2)
Acetaminophen (1) · Calcium Hydroxide (1) · Carticaine (1) · Duloxetine Hydrochloride (1) · Epinephrine (1) · Ketamine (1) · Memantine (1) · Metformin (1) · Morphine (1) · Pioglitazone (1) · Polymerase Chain Reaction (1) · Saline Solution (1) · Tacrolimus (1) · alanylglutamine (1) · avatrombopag (1)
Guangdong Provincial Hospital of Traditional Chinese Medicine (4) · Peking Union Medical College Hospital (3) · Affiliated Cancer Hospital & Institute of Guangzhou Medical University (1) · Armed Forces Institute of Dentistry, Pakistan (1) · Grace Lim, MD, MS (1) · Johns Hopkins University (1) · Menoufia University (1) · National Cancer Institute, Egypt (1) · Saint-Joseph University (1) · Seoul National University Hospital (1) · Suez Canal University (1) · The Hospital for Sick Children (1) · The University of Hong Kong (1)
China (7) · Egypt (3) · United States (2) · Lebanon (1) · Pakistan (1) · South Korea (1)
Chuanjian Lu, PhD (2) · Bing Han, Master (1) · Chuanjian Lu (1) · Frederick S Barrett, Ph.D. (1) · Grace Lim, MD, MS (1) · Jin-Tae Kim, M.D., Ph.D. (1) · Joe El Khoury, MD (1) · Kanza Zafar, BDS (1) · Mohamed Abdel Wadod, MD (1) · Shaimaa M. Mahfouz, PhD (1)
R01DA003889 (1)