273 completed, 57 unknown, 31 recruiting, 30 terminated. 137 Not applicable, 54 Phase 3, 46 Phase 4, 37 Phase 2, 15 Phase 1.
Follow this condition Literature Review of Fever trials Research Report on Fever
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of an Intervention Combining the Use of Standardized Information and Sending an SMS Advice Message to Parents Calling the SAMU Center 15 for Uncomplicated Fever in Children Standardized recommendations during emergency calls and sending advisory text message - Emergency Call, Fever; Pediatric Fever Management; Parental Anxiety | Not applicable | Not yet recruiting | Centre Hospitalier Annecy Genevois | 1792 | 2026-09-07 | 2025-12-02 |
| Efficacy and Safety of Daily Home-based Hyperthermic Baths for Reducing Epileptic Seizures in CDKL5 Deficiency Disorder: A PROBE Clinical Trial Home-based hyperthermic Baths - CDKL5 Deficiency Disorder | Not applicable | Not yet recruiting | Xuanwu Hospital, Beijing | 34 | 2026-08-01 | 2026-05-22 |
| Triage Performance and Physiological Predictors of Serious Illness in Febrile Children in the Pediatric Emergency Department Ministry of Health three-level color-coded triage - Fever, Triage | Recruiting | TC Erciyes University | 3000 | 2026-07-28 | 2026-08-05 | |
| Study to Investigate the Efficacy and Safety of Apomivir® Apomivir®, Placebo - Influenza | Phase 2 | Not yet recruiting | Far East Bio-Tec Co., Ltd | 196 | 2026-05-31 | 2025-05-14 |
| Hemorrhage Elimination During Lumbar Puncture Using Ultrasound Measurements (HELPUS) ultrasound contrast - Lumbar Puncture | Not applicable | Recruiting | Vanderbilt University Medical Center | 80 | 2026-05-16 | 2026-05-29 |
| Effectiveness of Best Care Practices in Acute Stroke in Conventional Hospitalization (BEST CARE ICTUS_HC) BEST CARE ICTUS_HC BUNDLE - Stroke, Acute Stroke | Not applicable | Recruiting | University of Malaga | 700 | 2026-05-12 | 2026-06-04 |
| Biomedical Signal Extraction From Symptom Descriptions: An Observational Registry Using the OpenGenome Platform OpenGenome AI Platform - Signs and Symptoms, Fever | Recruiting | OpenGenome | 1000 | 2026-05-05 | 2026-05-19 | |
| Diathermy On Diabetes Glucose Monitoring Effectiveness Type 1 Diabetes Mellitis | Not yet recruiting | University of Nottingham | 126 | 2026-05-01 | 2026-05-13 | |
| Permissive Hyperthermia in Acute Brain Injury Temperature < 39,5, Temperature <37.5 - Fever | Not applicable | Active not recruiting | Odense University Hospital | 20 | 2026-04-25 | 2026-07-16 |
| Comparison of FDG-PET/CT and CECT-CAP as Upfront Imaging Modality for the Diagnosis of Pyrexia of Unknown Origin FDG-PET, CECT, Standard care of therapy - Pyrexia | Not applicable | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 132 | 2026-04-09 | 2026-10-05 |
| Recovery After Fatigue in Young Athletes: Comparison Between TECAR Therapy and Cycle Ergometer" Tecar therapy (capacitive mode), Active recovery using cycle ergometer - Muscle Fatigue, Healthy Adult | Not applicable | Recruiting | Maimónides Biomedical Research Institute of Córdoba | 48 | 2026-04-01 | 2026-04-23 |
| Viromes in Infants Presenting With a Septic Syndrome biological samples - Fever, Viral Infection | Not applicable | Not yet recruiting | University Hospital, Montpellier | 130 | 2026-04-01 | 2026-03-17 |
| Antipyretic Therapy With and Without Cold Sponging Paracetamol, Paracetamol+Cold Sponging - Fever | Not applicable | Not yet recruiting | Muhammad Aamir Latif | 210 | 2026-03-01 | 2026-02-23 |
| Neuroendocrine Response in Pediatric Febrile Seizures Febrile Convulsion, Neuroendocrine Stress Response | Not yet recruiting | Aydin Adnan Menderes University | 120 | 2026-03-01 | 2026-03-11 | |
| Effect of Buzzy and Virtual Reality on Children Undergoing Venous Procedures Vein-imaging device + virtual reality headset group, Vein-imaging device + Buzzy group - Fever, Children | Not applicable | Recruiting | Bandırma Onyedi Eylül University | 105 | 2026-02-06 | 2026-10-20 |
| Clinical Accuracy Validation of the Moni-Patch Temperature Monitoring Patch System Moni-Patch Temperature Monitoring Patch System - Body Temperature, Febrile | Not applicable | Not yet recruiting | Murata Vios, Inc. | 105 | 2026-01-21 | 2026-02-09 |
| Assessing the Effectiveness of Large Language Model (LLM)-Enabled Nurse Treatment Planning in 2 Indian Districts AI-enabled clinical decision support tool (software) used by nurses, Physician consultation - Hypertension, Diabete Mellitus | Not applicable | Completed | Sarah Nabia | 736 | 2026-01-13 | 2026-08-05 |
| Using a Decision-making System to Support the Management of Fever and Acute Pain in Children Puntofarma® FEVER - Fever, Acute Pain | Not applicable | Terminated | Qwince Innovation S.r.l. | 100 | 2025-12-28 | 2026-10-13 |
| Masseter Muscle Stiffness After Heat Application and Percussion Therapy massage gun, heat treatment - Healthy Participants | Not applicable | Recruiting | University of Zurich | 40 | 2025-11-15 | 2025-11-19 |
| The Fever Clinic Acute Respiratory Cohort No intervention involved - Acute Respiratory Infections, Febrile Illnesses | Recruiting | Fudan University | 1000 | 2025-10-10 | 2025-12-12 |
Showing 20 of 433. Sign in to see all of them.
Neutropenia (43) · Infections (31) · Malaria (24) · Pain (22) · Fever of Unknown Origin (21) · Sepsis (21) · Cough (20) · Neoplasms (20) · Bacterial Infections (15) · Pneumonia (14) · Diarrhea (13) · Influenza, Human (13) · Febrile Neutropenia (12) · Headache (11)
Pathological Conditions, Signs and Symptoms (432) · Body Temperature Changes (430) · Signs and Symptoms (428) · Infections (144) · Pathologic Processes (100) · Neurologic Manifestations (64) · Hemic and Lymphatic Diseases (60) · Hematologic Diseases (58) · Respiratory Tract Diseases (58) · Nervous System Diseases (51) · Leukocyte Disorders (50) · Cytopenia (48) · Agranulocytosis (45) · Leukopenia (45) · Virus Diseases (44)
Acetaminophen (43) · Ibuprofen (23) · Diathermy (9) · Ciprofloxacin (6) · Standard of Care (5) · Vancomycin (5) · Control Groups (4) · Observation (4) · Piperacillin, Tazobactam Drug Combination (4) · Rapid Diagnostic Tests (4) · diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (4) · Amoxicillin (3) · Caspofungin (3) · Cefepime (3) · Cilastatin, Imipenem Drug Combination (3)
Assaf-Harofeh Medical Center (8) · Assistance Publique - Hôpitaux de Paris (8) · Duke University (7) · National Institute of Allergy and Infectious Diseases (NIAID) (6) · Columbia University (5) · Cumberland Pharmaceuticals (5) · Institute of Tropical Medicine, Belgium (5) · Mallinckrodt (5) · Pfizer (5) · Amgen (4) · GlaxoSmithKline (4) · M.D. Anderson Cancer Center (4) · MeMed Diagnostics Ltd. (4) · National Institutes of Health Clinical Center (CC) (4) · Novartis Pharmaceuticals (4)
United States (115) · France (32) · Turkey (Türkiye) (28) · Israel (26) · China (21) · Italy (21) · Germany (17) · Belgium (16) · Canada (16) · Switzerland (15) · United Kingdom (15) · Denmark (11) · Spain (11) · Australia (10) · Brazil (10)
Karen Broder, MD (4) · Melissa Stockwell, MD MPH (3) · Philip LaRussa, MD (3) · Thomas J. Walsh, MD (3) · Wendy O'Meara, PhD (3) · Carol Epstein, MD (2) · Emmanuel B Walter, MD, MPH (2) · Eran Kozer (2) · Heidi Hopkins, MD (2)
PMID 22520120, PMID 35639525, PMID 15459300, PMID 15806544, PMID 17556616, PMID 18178111, PMID 18503714, PMID 18668591, PMID 20187965, PMID 20231680, PMID 20431381, PMID 20488812, PMID 20591173, PMID 20692030, PMID 20692031, PMID 21126328, PMID 21176131, PMID 21353111, PMID 21394050, PMID 21396214, PMID 21698100, PMID 21837771, PMID 21883684, PMID 22087077, PMID 22182735, PMID 22182758, PMID 22183039, PMID 22220223, PMID 22271702, PMID 22373120, PMID 22420838, PMID 22443344, PMID 2265339, PMID 22905781, PMID 23023470, PMID 23102531, PMID 23170854, PMID 23340188, PMID 23358983, PMID 23561463, PMID 23774314, PMID 23786774, PMID 23936565, PMID 24023791, PMID 24037867, PMID 24378877, PMID 24386229, PMID 24395025, PMID 24431907, PMID 24618935
P30CA016672 (2), R01AI110478 (2), 1RC1LM010424-01 (1), 2014 (1), 2015 (1), 2016 (1), 2017 (1), 2018 (1), 2023 (1), 2025 (1), P30CA043703 (1), R01GM061834 (1), R01GM102130 (1), R01NS102176 (1), R44AI082728 (1)