12 completed, 7 recruiting, 7 unknown, 1 not yet recruiting. 10 Not applicable, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Recruiting 4, Unknown 4, Completed 2 |
| Phase 3 | 3 | Recruiting 2, Unknown 1 |
Follow Delirium, Postoperative: new trials by email Literature Review of Delirium, Postoperative trials Research Report on Delirium, Postoperative
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Audio-Recorded Messages Delivered Via iPad to Prevent Delirium in Hip Fracture Patients Audio-Recorded Reorientation Intervention - Delirium - Postoperative, Delirium and Post-operative Cognitive Dysfunction (POCD) | Not applicable | Recruiting | Sengkang General Hospital | 30 | 2025-09-29 | 2026-02-09 |
| The Impact of Smoking on the Prognosis of Elderly Surgical Patients none intervention - Delirium, Postoperative | Not yet recruiting | Affiliated Hospital of Nantong University | 121 | 2025-09-01 | 2025-01-16 | |
| The SCOPE Trial: Sleep, Cognition, and Pain Bundle vs. ERAS-cardiac for Postoperative Delirium Sleep Hygiene, Brain Game, and IV Acetaminophen Intervention, Control - Delirium, Postoperative, Delirium in Old Age | Phase 3 | Recruiting | Beth Israel Deaconess Medical Center | 406 | 2025-06-06 | 2026-04-15 |
| rSVO₂ and Postoperative Delirium Prediction Delirium, Postoperative | Completed | Wonkwang University Hospital | 300 | 2025-04-29 | 2025-06-06 | |
| Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass Transcranial Doppler measurement of the middle cerebral artery - Postoperative Cognitive Dysfunction, Delirium, Postoperative | Completed | Bakirkoy Dr. Sadi Konuk Research and Training Hospital | 110 | 2025-04-17 | 2026-10-20 | |
| Effect of Low-dose EsketaMine on dElirium in High-risk Elderly Patients uNdergoing elecTive Surgery (ELEMENT) Esketamine, Normal saline - Delirium in Old Age, Delirium, Postoperative | Not applicable | Recruiting | Nanfang Hospital, Southern Medical University | 1670 | 2025-02-12 | 2025-04-27 |
| Liraglutide in Preventing Delirium in Diabetic Elderly After Cardiac Surgery Liraglutide injection, Placebo injection - Delirium, Postoperative | Phase 3 | Recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 260 | 2024-11-19 | 2024-12-20 |
| Impact of Sleep Quality on Outcomes After Cardiac Surgery Eye masks and ear plugs - Sleep, Atrial Fibrillation | Not applicable | Unknown | Amrita Institute of Medical Sciences & Research Center | 100 | 2024-07-22 | 2024-09-25 |
| Metabolomics Analysis of Acute Kidney Injury and Delirium After Cardiac Surgery Serum metabolic profile - AKI - Acute Kidney Injury, Delirium, Postoperative | Completed | Xijing Hospital | 120 | 2024-07-20 | 2025-04-06 | |
| Depth of Anesthesia on Postoperative Delirium and Cognitive After Surgery Depth of anesthesia titration using pEEG - Delirium, Postoperative, Anesthesia | Not applicable | Recruiting | Auckland City Hospital | 2766 | 2024-05-20 | 2025-09-25 |
| Stanford ICU Delirium PIPRA Study Delirium, Cognitive Impairment | Completed | Stanford University | 199 | 2024-04-30 | 2024-08-09 | |
| The Effect of Listening to Holy Quran Recital on the Incidence of Delirium Post-CABG Holy Quran Recital - Coronary Artery Disease, Coronary Artery Bypass Graft Surgery | Not applicable | Unknown | Applied Science Private University | 264 | 2024-04-15 | 2024-04-05 |
| Effect of Percutaneous Acupoint Electrical Stimulation on Delirium Transcutaneous Electrical Acupoint Stimulation - Delirium, Postoperative | Not applicable | Unknown | Qin Zhang | 238 | 2024-03-01 | 2024-04-11 |
| Transcutaneous Acupoint Electrical Stimulation and Postoperative Delirium Delirium transcutaneous acupoint electrical stimulation - Delirium, Postoperative | Unknown | Qin Zhang | 476 | 2024-02-01 | 2024-04-09 | |
| Postoperative Delirium in the Post-anesthesia Care Unit NO Intervention - Delirium, Postoperative | Unknown | Qin Zhang | 3320 | 2024-01-20 | 2024-03-19 | |
| Reducing Delirium After CABG Surgery With Early Activation and Sleep-Promoting Routines DREAMS-OT - Delirium, Postoperative | Not applicable | Recruiting | National University Hospital, Singapore | 300 | 2024-01-08 | 2026-03-30 |
| Modulating Surgery-Induced Blood-Brain Barrier Disruption in Elderly Dexmedetomidine Injection [Precedex], Lidocaine IV, normal saline - Delirium, Postoperative | Not applicable | Unknown | Samsung Medical Center | 108 | 2023-10-25 | 2024-04-17 |
| Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunction and Delirium Perioperative Assessment - Postoperative Cognitive Dysfunction, Delirium, Postoperative | Completed | Ankara University | 137 | 2023-09-27 | 2026-04-03 | |
| Sleep and Circadian Rhythm Biomarkers of Postoperative Delirium Delirium, Postoperative, Cognitive Decline | Recruiting | Massachusetts General Hospital | 150 | 2023-09-12 | 2026-09-14 | |
| Optic Nerve Sheath Diameter is Associated With Postoperative Delirium in Patients Undergoing Open Heart Surgery ONSD - Delirium, Postoperative, Cardiac Disease | Completed | Samsun University | 90 | 2023-08-07 | 2024-09-05 |
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Emergence Delirium (27) · Delirium (16) · Cognitive Dysfunction (5) · Neuroinflammatory Diseases (2) · Postoperative Cognitive Complications (2) · Abdominal Neoplasms (1) · Acute Kidney Injury (1) · Atrial Fibrillation (1) · Cognition Disorders (1) · Coronary Artery Disease (1) · Delayed Emergence from Anesthesia (1) · Dementia (1) · Heart Diseases (1) · Heart Valve Diseases (1) · Malnutrition (1)
Confusion (27) · Mental Disorders (27) · Nervous System Diseases (27) · Neurobehavioral Manifestations (27) · Neurocognitive Disorders (27) · Neurologic Manifestations (27) · Pathologic Processes (27) · Pathological Conditions, Signs and Symptoms (27) · Signs and Symptoms (27) · Postoperative Complications (26) · Delirium (11) · Cognition Disorders (5) · Cardiovascular Diseases (3) · Heart Diseases (2) · Inflammation (2)
Saline Solution (3) · Dexmedetomidine (2) · Ear Protective Devices (1) · Esketamine (1) · Liraglutide (1)
Qin Zhang (3) · Huazhong University of Science and Technology (2) · Affiliated Hospital of Nantong University (1) · Amrita Institute of Medical Sciences & Research Center (1) · Andrzej Frycz Modrzewski Krakow University (1) · Ankara University (1) · Applied Science Private University (1) · Auckland City Hospital (1) · Bakirkoy Dr. Sadi Konuk Research and Training Hospital (1) · Beth Israel Deaconess Medical Center (1) · Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital (1) · Gonul Kara Soylemez (1) · Kilis 7 Aralik University (1) · Massachusetts General Hospital (1) · Nanfang Hospital, Southern Medical University (1)
China (10) · Turkey (Türkiye) (6) · United States (3) · Singapore (2) · South Korea (2) · India (1) · New Zealand (1) · Poland (1)
Qin Zhang, phd (2) · Yuke Tian, M.D. (2) · Carolyn Deng (1) · Chao-Chao Zhong (1) · Cheol Lee, M.D.,Ph.D (1) · Chuanhan Zhang, M.D. (1) · Chuanhan Zhang, MD. (1) · Dongjin Wang, PhD，MD (1) · Gonul Kara Soylemez, MD (1) · Jiseon Jeong (1) · Jose R Maldonado, MD (1) · Ke-Xuan Liu, MD (1) · Kun Hu, PhD (1) · Lei Gao, MBBS (1) · Qin Zhang (1)
PMID 18686756, PMID 21929765, PMID 28601132, PMID 33189147, PMID 37290122, PMID 37819663, PMID 38643014, PMID 39695628, PMID 40596877