9 completed, 4 unknown, 3 active not recruiting, 1 not yet recruiting. 5 Phase 2, 4 Phase 3, 3 Not applicable, 2 Phase 1, 1 Phase 4.
Follow Degenerative Osteoarthritis: new trials by email Literature Review of Degenerative Osteoarthritis trials Research Report on Degenerative Osteoarthritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Determine the Safety and Efficacy of TG-C in Subjects With Symptomatic Early Hip Osteoarthritis TG-C, Placebo Control - Degenerative Osteoarthritis | Phase 2 | Not yet recruiting | Kolon TissueGene, Inc. | 255 | 2027-10-01 | 2026-08-20 |
| Platelet-Rich Plasma and the Effects of NSAIDs on Pain and Functional Scores in Knee Osteoarthritis Ibuprofen and PRP, Acetaminophen and PRP, Placebo and PRP - Osteoarthritis of the Knee, Degenerative Osteoarthritis | Phase 1 / Phase 2 | Withdrawn | QC Kinetix LLC | 2023-11-01 | 2024-10-09 | |
| Evaluation of the PHENO4U Data Platform in Patients Undergoing Total Knee Arthroplasty Pheno4U - Degenerative Osteoarthritis, Rheumatoid Arthritis | Recruiting | Aesculap AG | 600 | 2022-09-28 | 2026-02-27 | |
| Continuous Distal Adductor Canal Block With Periarticular Local Anesthetic Infiltration Versus Continuous Distal Adductor Canal Block Alone for Analgesia After Total Knee Arthroplasty Distal adductor canal block, Distal adductor canal block and Periarticular block - Degenerative Osteoarthritis | Not applicable | Unknown | Yonsei University | 66 | 2022-07-17 | 2024-01-11 |
| Serum Nesfatin-1 and Human Cartilage Glycoprotein-39 Levels in Knee Osteoarthritis exercise, intraarticular knee PRP injections - Osteoarthritis of Knee, Degenerative Osteoarthritis | Not applicable | Completed | Kayseri City Hospital | 30 | 2022-06-01 | 2024-02-23 |
| Study to Determine the Efficacy and Safety of TG-C in Subjects With Kellgren/Lawrence Grade 2 or 3 OA of the Knee TG-C, Placebo Control - Degenerative Osteoarthritis | Phase 3 | Completed | Kolon TissueGene, Inc. | 531 | 2021-12-09 | 2026-08-20 |
| Plasmafit® Revision Structan® Hip Endoprosthesis Cup Plasmafit® Revision Structan® - Osteolysis, Arthroplasty Complications | Active not recruiting | Aesculap AG | 60 | 2021-04-12 | 2026-05-06 | |
| AESCULAP® Plasmafit® Cementless Acetabular System With Vitelene® Vitamin E Stabilized Highly Crosslinked Polyethylene Plasmafit® Vitelene® Vitamin E - Osteoarthritis, Hip, Rheumatic Arthritis | Completed | Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty | 400 | 2020-08-01 | 2023-07-06 | |
| Orthopilot Elite Post-Market Clinical Follow-Up Computer assisted primary total knee replacement with OrthoPilot FS101 navigation system and Software 5.1, Computer assisted primary total knee replacement with OrthoPilot Elite navigation system and Software 6.0 - Degenerative Osteoarthritis, Rheumatoid Arthritis | Completed | Aesculap AG | 217 | 2019-07-01 | 2023-01-17 | |
| Cutibacterium Dermal Colonization: Implications for Total Hip Arthroplasty Benzoyl peroxide gel - Degenerative Osteoarthritis | Phase 4 | Unknown | Colorado Joint Replacement | 496 | 2019-02-02 | 2023-01-10 |
| A Study to Determine the Safety and Efficacy of TG-C in Subjects With Kellgren and Lawrence Grade 2 or 3 OA of the Knee TG-C, Placebo Control - Degenerative Osteoarthritis | Phase 3 | Active not recruiting | Kolon TissueGene, Inc. | 535 | 2018-10-30 | 2026-08-20 |
| CoreHip - Post Market Clinical Follow-Up Study CoreHip Total Hip Arthroplasty - Degenerative Osteoarthritis, Rheumatic Arthritis | Active not recruiting | Aesculap AG | 248 | 2018-10-16 | 2026-03-31 | |
| Non-Interventional, Multicenter Bicontact® E PMCF Study Degenerative Osteoarthritis, Rheumatoid Arthritis | Completed | Aesculap AG | 73 | 2017-02-01 | 2019-09-19 | |
| UCMSC Transplantation in the Treatment of Cartilage Damage umbilical cord mesenchymal stem cells, Hyaluronic acid - Cartilage Damage, Degenerative Osteoarthritis | Phase 1 / Phase 2 | Unknown | South China Research Center for Stem Cell and Regenerative Medicine | 20 | 2016-06-01 | 2016-05-18 |
| VEGA Prospective Kiel VEGA Knee - Degenerative Osteoarthritis, Rheumatoid Arthritis | Completed | Aesculap AG | 84 | 2016-05-01 | 2019-01-23 | |
| All Polyethylene Tibia-VEGA Kiel All-Poly - Degenerative Osteoarthritis, Rheumatoid Arthritis | Completed | Aesculap AG | 70 | 2016-03-01 | 2023-06-26 | |
| Determine the Efficacy of TT-173. Reducing the the Total Blood Loss Associated With Total Knee Arthroplasty (HESTAT) placebo, TT-173 - Degenerative Osteoarthritis | Phase 2 / Phase 3 | Unknown | Thrombotargets Europe S.L | 210 | 2016-01-01 | 2018-02-22 |
| Follow-Up Study of CARTISTEM® Versus Microfracture for the Treatment of Knee Articular Cartilage Injury or Defect CARTISTEM, Microfracture - Degenerative Osteoarthritis, Defect of Articular Cartilage | Phase 3 | Completed | Medipost Co Ltd. | 103 | 2012-06-01 | 2017-04-20 |
| Efficacy and Safety Study of Lumbar Interbody Fusion With MatriTMBONE Associated With Autologous Bone Marrow The Transforaminal Lumbar Interbody Fusion (TLIF) surgery - Degenerative Osteoarthritis, Degenerative Lumbar Vertebra | Phase 2 | Terminated | University Hospital, Bordeaux | 32 | 2011-05-01 | 2026-06-18 |
| Study of Subtalar Arthrodesis Using AlloStem® Versus Autologous Bone Graft Subtalar Arthrodesis - Degenerative Osteoarthritis, Post-traumatic; Arthrosis | Not applicable | Completed | AlloSource | 140 | 2010-06-01 | 2018-04-13 |
Joint Diseases (20) · Arthritis, Rheumatoid (6) · Osteoarthritis (5) · Rheumatic Fever (3) · Femur Head Necrosis (2) · Hip Fractures (2) · Osteoarthritis, Knee (2) · Ankylosis (1) · Congenital Abnormalities (1) · Femoral Neck Fractures (1) · Joint Instability (1) · Knee Injuries (1) · Osteoarthritis, Hip (1) · Osteolysis (1) · Pain (1)
Musculoskeletal Diseases (20) · Arthritis (12) · Rheumatic Diseases (12) · Connective Tissue Diseases (9) · Skin and Connective Tissue Diseases (9) · Autoimmune Diseases (6) · Immune System Diseases (6) · Leg Injuries (4) · Wounds and Injuries (4) · Bacterial Infections (3) · Bacterial Infections and Mycoses (3) · Femoral Fractures (3) · Fractures, Bone (3) · Gram-Positive Bacterial Infections (3) · Hip Injuries (3)
Saline Solution (3) · Arthroplasty, Replacement, Knee (2) · Acetaminophen (1) · Arthroplasty, Subchondral (1) · Benzoyl Peroxide (1) · Exercise (1) · Ibuprofen (1) · Surgical Procedures, Operative (1) · clindamycin phosphate benzoyl peroxide combination (1)
Aesculap AG (7) · Kolon TissueGene, Inc. (3) · AlloSource (1) · Colorado Joint Replacement (1) · Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty (1) · Kayseri City Hospital (1) · Medipost Co Ltd. (1) · QC Kinetix LLC (1) · South China Research Center for Stem Cell and Regenerative Medicine (1) · Thrombotargets Europe S.L (1) · University Hospital, Bordeaux (1) · Yonsei University (1)
Germany (6) · United States (5) · South Korea (2) · France (1) · Japan (1) · Russia (1) · Spain (1) · Switzerland (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Moon Jong Noh, PhD (3) · Ludger Gerdesmeyer, Professor (2) · Andrew Murphy, MD (1) · Beom-gu Lee, MD, PhD (1) · Choong-hyuk Choi, MD, PhD (1) · Christiaan Coetzee, MD (1) · Chul-won Ha, MD, PhD (1) · Henning Windhagen, Prof. Dr. med. (1) · Hong-chul Lim, MD, PhD (1) · Hwa-jae Jeong, MD, PhD (1) · Jae-doo Yoo, MD, PhD (1) · Jason M Jennings, MD DPT (1)
PMID 28687347, PMID 33229973, PMID 33490296, PMID 38739584
2015 (1)