49 completed, 10 unknown, 3 not yet recruiting, 2 recruiting. 28 Phase 4, 15 Phase 3, 8 Not applicable, 6 Phase 2, 4 Phase 1.
Follow Benzoyl Peroxide: new trials by email Literature Review of Benzoyl Peroxide trials Research Report on Benzoyl Peroxide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clascoterone Versus Clindamycin Added to Adapalene/Benzoyl Peroxide for Moderate Facial Acne Clascoterone 1% cream, Clindamycin 1% lotion, Adapalene 0.1%/benzoyl peroxide 2.5% gel - Acne Vulgaris | Phase 4 | Not yet recruiting | Allied Hospital Faisalabad | 118 | 2026-11-01 | 2026-10-19 |
| Radiofrequency Treatment Versus Topical Therapy for Facial Acne Vulgaris Adapalene 0.1% and Benzoyl Peroxide 2.5% gel, Sequential Radiofrequency Treatment - Acne Vulgaris | Not applicable | Recruiting | Jeisys Medical Inc | 60 | 2026-09-15 | 2026-09-04 |
| Evaluating Benzoyl Peroxide for Preventing Recurrence of HSV-1 Outbreaks With Rescue Crossover Option Benzoyl Peroxide 10% Bar, Placebo - HSV | Phase 2 | Not yet recruiting | Greg Bew | 100 | 2026-01-01 | 2025-08-05 |
| Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Triple Combination Gel in Canadian Patients With Acne Vulgaris clindamycin phosphate, adapalene and benzoyl peroxide - Acne Vulgaris | Completed | Bausch Health Americas, Inc. | 200 | 2025-10-02 | 2026-09-09 | |
| An Observational Clinical Study to Evaluate the Efficacy of the CeraVe Skin Care Line CeraVe - Acne | Not yet recruiting | ChinaNorm | 240 | 2025-06-27 | 2025-06-29 | |
| Benzoyl Peroxide and Electrocautery Skin Incision to Eradicate Cutibacterium Acnes Benzoyl Peroxide Topical, Electrocautery surgical skin incision - Prosthetic-joint Infection | Phase 4 | Withdrawn | University of Missouri-Columbia | 2024-06-01 | 2024-07-15 | |
| Effectivity and Safety of Combination Cream of Salicylic Acid, Aqua Posae Filiformis, Niacinamide, Lipohydroxy Acid, Procerad and Zinc PCA Combination Cream, Adapalene 0,1% cream - Acne Vulgaris | Phase 1 | Unknown | Dr.dr.Irma Bernadette, SpKK (K) | 284 | 2022-08-01 | 2023-04-06 |
| MC RCT - BPO vs Adapalene Benzoyl peroxide, Adapalene Gel - Molluscum Contagiosum | Phase 3 | Withdrawn | University of Oklahoma | 2022-05-18 | 2024-03-06 | |
| Cutibacterium Acnes in Deep Tissues in Primary Spine and Shoulder Surgery Benzoyl peroxide - Rotator Cuff Tear Arthropathy, Spine Degeneration | Not applicable | Unknown | Hospital del Mar | 200 | 2022-05-01 | 2022-05-02 |
| Comparing Efficacy of Azithromycin and Probiotics for Treatment of Acne Vulgaris Azithromycin, Probiotic Formula, Benzoyl Peroxide 4 % Topical Cream - Acne Vulgaris | Phase 3 | Completed | Pak Emirates Military Hospital | 75 | 2021-10-15 | 2022-12-05 |
| Profiling the Skin Microbiome in Response to Altreno in Acne Patients Altreno, Benzoyl peroxide - Acne, Healthy | Phase 4 | Completed | Beth Israel Deaconess Medical Center | 25 | 2021-04-23 | 2024-02-06 |
| Optimization of Skin Preparation to Reduce Cutibacterium Acnes Colonization in Superficial and Deep Samples During Prosthetic Shoulder Surgery in Male Patients 5% benzoyl peroxide - Cutibacterium Acnes Infection | Phase 3 | Recruiting | Nantes University Hospital | 110 | 2020-06-19 | 2025-05-01 |
| Influence of Obuvacaine Hydrochloride Eye Drops on the Comfort of Meibomian Gland Massage Patients Benoxyl - Meibomian Gland Massage is Important to Delay the Development of Meibomian Gland Dysfunction | Unknown | Aier School of Ophthalmology, Central South University | 100 | 2020-06-01 | 2020-09-29 | |
| Cutibacterium Dermal Colonization: Implications for Total Hip Arthroplasty Benzoyl peroxide gel - Degenerative Osteoarthritis | Phase 4 | Unknown | Colorado Joint Replacement | 496 | 2019-02-02 | 2023-01-10 |
| The Effect of Pretreatment for Propionibacterium Acnes on Surgical Site Burden in Shoulder Arthroplasty Blue Light Phototherapy, Benzyl Peroxide, Control - Shoulder Arthroplasty | Not applicable | Completed | Albany Medical College | 120 | 2019-01-10 | 2023-08-30 |
| Effects of Oral Zinc Gluconate Among Acne Vulgaris Patients Zinc gluconate, Adapalene 0.003 MG/MG / Benzoyl Peroxide 0.025 MG/MG Topical Gel [Epiduo], Placebo - Acne Vulgaris | Phase 4 | Completed | East Avenue Medical Center, Philippines | 23 | 2018-12-21 | 2022-05-11 |
| BPO vs Hibiclens Soap for Surgical Preparation Benzoyl Peroxide 10% Bar, Chlorhexidine Gluconate - Propionibacterium Acnes | Phase 4 | Completed | University of Washington | 50 | 2018-09-10 | 2022-03-15 |
| Topical Treatment and Prevalence of P. Acnes Clindamycin 1% Gel, Benzoyl peroxide 5% gel, BenzaClin 5%-1% Topical Gel - Surgical Site Infection | Phase 2 | Completed | University of Southern California | 12 | 2017-09-11 | 2019-11-13 |
| Pirfenidone Plus M-DDO Gel in Moderate and Severe Acne PDF+M-DDO, A+PBO - Acne Vulgaris Superficial Mixed Comedonal and Inflammatory | Phase 1 / Phase 2 | Completed | University of Guadalajara | 82 | 2017-03-27 | 2023-07-06 |
| Perimenstrual Acne With Clindamycin Phosphate and Benzoyl Peroxide lidamycin phosphate and benzoyl peroxide 1.2%/3.75% combination - Actinic Keratosis | Phase 2 | Completed | Icahn School of Medicine at Mount Sinai | 22 | 2017-01-01 | 2020-09-04 |
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Acne Vulgaris (51) · Herpes Simplex (1) · Inflammation (1) · Joint Diseases (1) · Keratosis, Actinic (1) · Molluscum Contagiosum (1) · Patient Compliance (1) · Rotator Cuff Tear Arthropathy (1) · Skin Diseases (1) · Surgical Wound Infection (1)
Galderma R&D (11) · Stiefel, a GSK Company (8) · Galderma Laboratorium GmbH (3) · Bausch Health Americas, Inc. (2) · Dow Pharmaceutical Sciences (2) · GlaxoSmithKline (2) · Northwestern University (2) · Wake Forest University (2) · Zeichner, Joshua, M.D. (2) · Zurita Laboratorio Farmaceutico Ltda. (2) · Actavis Mid-Atlantic LLC (1) · Aier School of Ophthalmology, Central South University (1) · Albany Medical College (1) · Allergan (1) · Allied Hospital Faisalabad (1)
United States (37) · Canada (6) · Belize (3) · Japan (3) · Brazil (2) · Germany (2) · India (2) · Mexico (2) · Pakistan (2) · Argentina (1) · China (1) · France (1) · Hungary (1) · Indonesia (1) · Philippines (1)
Michael Graeber, MD (3) · Amy Paller, MD (2) · Harald PM Gollnick, Prof. Dr. (2) · Ronald W Gottschalk, MD (2) · Adelaide Hebert, MD (1) · Akbar W Syed, PhD (1) · Alan Fleischer, MD (1) · Ana Rossi, MD (1) · Andrea Zaenglein, MD (1) · Anjali Shroff, MD (1) · Arie Kusumawardani (1) · Boni Elewski, MD (1) · Charles Lynde, MD (1)
PMID 12413768, PMID 19651954, PMID 20684151, PMID 21421326, PMID 21607190, PMID 22846406, PMID 23172325, PMID 23513559, PMID 25187583, PMID 26178890, PMID 27541148, PMID 27869623, PMID 28678647, PMID 28900751, PMID 29537444, PMID 29870447, PMID 30054245