30 completed, 14 recruiting, 14 unknown, 11 active not recruiting. 25 Not applicable, 9 Phase 2, 6 Phase 3, 5 Phase 4, 3 Phase 1.
Follow Femur Head Necrosis: new trials by email Literature Review of Femur Head Necrosis trials Research Report on Femur Head Necrosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Study of Early Stage Osteonecrosis of Femoral Head With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ONFH) Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#), core decompression - Osteonecrosis of Femoral Head | Phase 1 / Phase 2 | Suspended | Sclnow Biotechnology Co., Ltd. | 30 | 2026-12-31 | 2026-04-23 |
| DEXA Bone Density Analysis of the CoreHip® Prosthesis System Primary hip replacement with cementless stem - Primary Osteoarthritis, Cartilage Degeneration | Not applicable | Not yet recruiting | Aesculap AG | 40 | 2026-12-01 | 2026-10-16 |
| Screening for Biomarkers of Osteonecrosis of the Femoral Head Osteonecrosis of the Femoral Head | Recruiting | The First Affiliated Hospital of Xinxiang Medical College | 300 | 2026-04-20 | 2026-04-22 | |
| Clinical Transformation of Bone Reconstruction With Autologous Bone Marrow Mesenchymal Stem Cells in Vitro to Repair Avascular Necrosis of Femur Head Tissue-engineered bone - Avascular Necrosis of Femur Head | Not applicable | Recruiting | The First Affiliated Hospital of Xinxiang Medical College | 30 | 2026-04-20 | 2026-05-04 |
| Alendronate for Osteonecrosis in Adults With Sickle Cell Disease Alendronate Sodium - Sickle Cell Disease, Sickle Cell Anemia | Phase 2 | Recruiting | University of California, Davis | 30 | 2026-03-09 | 2026-07-16 |
| Early Feasibility Study of Cartilage Defect Repair ReNew Hip Implant - Osteoarthritis, Hip, Femoroacetabular Impingement | Not applicable | Active not recruiting | Cytex Therapeutics, Inc. | 15 | 2025-11-06 | 2026-09-16 |
| EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN)) EMPHASYS Cup with VHN - Osteoarthritis, Traumatic Arthritis | Not applicable | Recruiting | DePuy Orthopaedics | 118 | 2025-10-24 | 2026-11-04 |
| Z1 Hip System: Post-Market Clinical Follow Up Study Z1 Femoral Hip System - Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck | Recruiting | Zimmer Biomet | 300 | 2025-10-13 | 2026-10-16 | |
| Influence of Antiseptic Washes on Wound Healing Complications After THA lavage chlorhexidine, lavage povidone-iodine - Hip Osteoarthritis, Avascular Necrosis of Femur Head | Not applicable | Recruiting | F. Johannes Plate | 420 | 2025-10-09 | 2026-02-05 |
| Comparison of the Efficacy of Pericapsular Nerve Group Block Alone Versus Pericapsular Nerve Group Block Combined With Superior Cluneal and Superior Gluteal Nerve Blocks in Patients Undergoing Hip Surgery 15 ml Bupivacaine Hcl 0.25% injection, 20 mL bupivacaine 0.25% injection - Hip Osteoarthritis, Osteonecrosis of the Femoral Head | Not applicable | Enrolling by invitation | Ataturk University | 60 | 2025-09-01 | 2025-12-08 |
| Investigation of the Effect of Hyperbaric Oxygen Therapy in Patients With Avascular Necrosis Avascular Necrosis of Femur Head | Active not recruiting | Dr. Lutfi Kirdar Kartal Training and Research Hospital | 20 | 2025-08-19 | 2025-08-26 | |
| Robotic Arm-assisted THA Vs. Conventional THA in Legg-Calvé-Perthes Disease robotic arm-assisted total hip replacement, conventional total hip replacement - Legg-Calvé-Perthes Disease | Not applicable | Enrolling by invitation | Second Affiliated Hospital, Zhejiang University, School of Medicine | 50 | 2025-07-28 | 2025-08-14 |
| Clinical Outcomes of Primary Cementless Total Hip Arthroplasty Using the Collarless Actis Stem Collarless Actis femoral stem - Osteoarthritis, Hip, Femur Head Necrosis | Not applicable | Recruiting | Seoul National University Bundang Hospital | 210 | 2025-06-18 | 2026-09-18 |
| Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis Core Decompression, Core Decompression Procedure with Autologous Bone Marrow Aspirate Concentrate - Osteonecrosis of the Femoral Head, Avascular Necrosis of the Femoral Head | Not applicable | Recruiting | Johns Hopkins University | 192 | 2025-04-01 | 2026-09-17 |
| Desflurane Potentially Induces Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Perioperative Procedures by Modulating Cdc42 and Clock Proteins Desflurane Inhalation, mechanical ventilation (MV) - Avascular Necrosis of the Femoral Head, Coronary Artery Disease (CAD) | Not applicable | Not yet recruiting | Xiaguang Duan | 60 | 2025-02-01 | 2025-01-14 |
| Triple-Modal Therapy in Early-Stage Femoral Head Osteonecrosis (TM-ONFH) Core decompression, stromal vascular fraction (SVF), Hyperbaric Oxygen Therapy (HBOT) - Osteonecrosis of the Femoral Head | Completed | Ankara City Hospital Bilkent | 24 | 2025-01-22 | 2026-05-06 | |
| A Phase II Trial of RAB001 (LLP2A-Alendronate) for Steroid-Induced Early-Stage Osteonecrosis of the Femoral Head RAB001 high dose, RAB001 medium dose, RAB001 low dose - Osteonecrosis, Osteonecrosis of the Femoral Head | Phase 2 | Active not recruiting | ZhongShan LaiBo RuiChen BioMedicine Co.,Ltd. | 161 | 2024-12-24 | 2026-03-24 |
| Bupivacaine Liposome Plus Bupivacaine or Ropivacaine for Pericapsular Nerve Group Block in Hip Arthroplasty (PENG) Liposomal bupivacaine plus bupivacaine, Ropivacaine - Femoral Neck Fractures, Femur Head Necrosis | Phase 4 | Recruiting | Huazhong University of Science and Technology | 60 | 2024-12-04 | 2026-03-13 |
| Multicentre SMS Study - FR Total Hip Arthroplasty - Dysplasia of Hip Joint, Hip Osteoarthritis | Recruiting | Medacta International SA | 260 | 2024-09-01 | 2026-10-08 | |
| Difference in Return to Sports Activity After Hip Arthroplasty by THR or Resurfacing total hip replacement - Hip Arthrosis, Femur Head Necrosis | Unknown | Société Française de chirurgie de la Hanche et du Genou | 500 | 2024-06-01 | 2024-05-10 |
Showing 20 of 84. Sign in to see all of them.
Legg-Calve-Perthes Disease (25) · Osteoarthritis, Hip (24) · Osteonecrosis (18) · Osteoarthritis (15) · Arthritis, Rheumatoid (10) · Femoral Neck Fractures (9) · Hip Fractures (8) · Hip Dislocation (5) · Hip Dislocation, Congenital (5) · Musculoskeletal Diseases (4) · Bone Diseases (3) · Arthritis (2) · Developmental Dysplasia of the Hip (2) · Infertility (2)
Bone Diseases (81) · Musculoskeletal Diseases (80) · Pathological Conditions, Signs and Symptoms (73) · Necrosis (72) · Pathologic Processes (72) · Osteonecrosis (66) · Rheumatic Diseases (39) · Joint Diseases (38) · Arthritis (37) · Osteoarthritis (22) · Wounds and Injuries (18) · Hip Injuries (17) · Fractures, Bone (16) · Femoral Fractures (15)
Arthroplasty, Replacement, Hip (6) · Alendronate (2) · Bupivacaine (2) · Osteotomy (2) · Saline Solution (2) · Anesthesia, General (1) · Arthroplasty, Subchondral (1) · Aspirin (1) · Enoxaparin (1) · Hyperbaric Oxygenation (1) · Injections (1) · Intubation, Intratracheal (1) · Ketoconazole (1) · Pamidronate (1) · Patient Reported Outcome Measures (1)
Aesculap AG (6) · Zimmer Biomet (5) · Medacta International SA (4) · Seoul National University Bundang Hospital (3) · Corin (2) · DePuy Orthopaedics (2) · Ewha Womans University (2) · Stryker Trauma and Extremities (2) · The First Affiliated Hospital of Xinxiang Medical College (2) · ZhongShan LaiBo RuiChen BioMedicine Co.,Ltd. (2) · Ankara City Hospital Bilkent (1) · Assaf-Harofeh Medical Center (1) · Ataturk University (1) · Banc de Sang i Teixits (1) · Baxter Healthcare Corporation (1)
China (14) · United States (12) · Germany (11) · France (9) · South Korea (7) · Canada (5) · Italy (5) · Spain (5) · Austria (4) · Turkey (Türkiye) (4) · Japan (3) · Norway (3) · Switzerland (3) · Taiwan (3) · Netherlands (2)
Alexandru Nebunescu-Schirliu, MD (1) · Arny Ferrando, PhD (1) · Cecilia Pasucal-Garrido, MD (1) · Chih-Hung Hung, MD (1) · Christophe Hulet, MD, PR (1) · Christopher Travers, MD (1) · David Wilson, Dr. (1) · Deborah German, BS (1) · Enrique Gomez-Barrena, Prof (1) · Fan J Shao, Doctor (1) · Florian Gottsauner-Wolf, MD (1) · Frank J Plate, MD, PhD (1)
PMID 19915292, PMID 19934701, PMID 21643924, PMID 25315149, PMID 25769789, PMID 32678055, PMID 32871293, PMID 33535589, PMID 36042064, PMID 36961220, PMID 37718446, PMID 41188948
2018 (1), K23HL148310 (1), R01AR052293 (1), U01AR080993 (1)