11 completed, 5 unknown, 4 recruiting, 2 active not recruiting. 8 Not applicable, 3 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 4, Unknown 2, Active not recruiting 1, Withdrawn 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Phase 4 | 1 | Completed 1 |
Follow Osteolysis: new trials by email Literature Review of Osteolysis trials Research Report on Osteolysis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Incidence & Clinical Significance of Osteolysis Following PEEK Suture Anchor Use in Hand & Wrist Surgery Osteolysis | Not yet recruiting | University of Colorado, Denver | 180 | 2026-01-01 | 2025-10-06 | |
| Regular Home-use Dual Light Photodynamic Therapy in the Prevention of Osteolysis After Dental Implant Surgery Lumoral Treatment, Standard oral hygiene - Osteolysis, Dental Implants | Not applicable | Withdrawn | Koite Health Oy | 2025-12-01 | 2024-11-19 | |
| Pediatric Arthropathy Beyond Inflammation: Clinical Spectrum and Diagnostic Approach at Assiut University Children Hospital Mucopolysaccharidoses, Progressive Pseudorheumatoid Dysplasia | Not yet recruiting | Assiut University | 35 | 2025-09-01 | 2025-09-15 | |
| Feasibility, Safety and Effectivity of an Exercise Intervention for Newly Diagnosed Multiple Myeloma Patients During Induction Therapy Exercise, Control group - Multiple Myeloma Bone Lesions | Not applicable | Active not recruiting | University Hospital Heidelberg | 50 | 2023-04-14 | 2025-06-18 |
| A Prospective Natural History Study of Lymphatic Anomalies Lymphatic Diseases, Lymphatic Abnormalities | Recruiting | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 1200 | 2023-03-20 | 2026-10-23 | |
| Total Knee Arthroplasty With Vitamin E Polyethylene GKS Prime Flex Mobile knee - Knee Osteoarthritis | Completed | Permedica spa | 186 | 2022-04-12 | 2025-01-03 | |
| Bio-Integrative Versus Metallic Screws for Calcaneus Osteotomies Calcaneus Osteotomy (Metallic), Calcaneus Osteotomy (Bio-integrative) - Flatfoot, Bone Resorption | Not applicable | Unknown | University of Iowa | 44 | 2021-11-01 | 2023-09-06 |
| Functional Exercise Tests in Patients With Systemic Sclerosis 6-minute walk test part one, 6-minute walk test part two, 1-minute sit-to-stand test - Scleroderma, Systemic, Lung Diseases, Interstitial | Unknown | University of Aarhus | 83 | 2021-07-27 | 2022-05-20 | |
| Plasmafit® Revision Structan® Hip Endoprosthesis Cup Plasmafit® Revision Structan® - Osteolysis, Arthroplasty Complications | Active not recruiting | Aesculap AG | 60 | 2021-04-12 | 2026-05-06 | |
| Relationship Between Circulating Sclerostin and Bone Lesions in Patients With Mastocytosis SCLEROSTIN - Mastocytosis, Bones | Recruiting | Medical University of Lublin | 50 | 2019-09-01 | 2024-06-03 | |
| Imaging of Lymphatic Anomalies Dynamic Contrast Enhanced Magnetic Resonance Lymphangiography (DCMRL), Heavy Weighted T2 Imaging (T2W), Lymph Node Access - Gorham Disease, Lymphatic Diseases | Not applicable | Completed | Children's Hospital of Philadelphia | 10 | 2016-04-01 | 2018-03-21 |
| Denosumab for Treating Periprosthetic Osteolysis. Denosumab, Placebo - Osteolysis | Phase 2 | Unknown | Olof Skoldenberg | 20 | 2015-08-01 | 2019-02-07 |
| Identification of Biomarkers for Patients with Vascular Anomalies Vascular Anomaly, Generalized Lymphatic Anomaly | Recruiting | Children's Hospital Medical Center, Cincinnati | 1000 | 2015-04-01 | 2024-11-06 | |
| Prolonged Protection From Bone Disease in Multiple Myeloma Zoledronic acid - Multiple Myeloma | Phase 4 | Completed | Thomas Lund | 158 | 2015-01-01 | 2023-02-17 |
| Lymphatic Anomalies Registry for the Assessment of Outcome Data Lymphatic Malformation, Generalized Lymphatic Anomaly (GLA) | Recruiting | Boston Children's Hospital | 1000 | 2013-06-01 | 2026-09-10 | |
| Post-Market Study of the Modular Revision Hip System Modular Revision Hip System - Aseptic Loosening, Osteolysis | Terminated | Encore Medical, L.P. | 16 | 2012-01-01 | 2018-10-10 | |
| A Five-Year Metal-on-Metal Retrospective Clinical Study Metal-on-metal primary total hip arthroplasty (DePuy ) - Osteoarthritis | Completed | Anderson Orthopaedic Research Institute | 126 | 2011-12-01 | 2013-10-09 | |
| Tivantinib in Treating Patients With Relapsed, or Relapsed and Refractory Multiple Myeloma Tivantinib, Diagnostic laboratory biomarker analysis, Questionnaire administration - Refractory Multiple Myeloma | Phase 2 | Completed | National Cancer Institute (NCI) | 16 | 2011-11-01 | 2019-08-28 |
| Double-Blinded Clinical Trial Using Apatone®B for Symptomatic Postoperative Total Joint Replacements Placebo, Apatone®B - Edematous, Synovitis | Phase 2 | Completed | IC-MedTech Corporation | 57 | 2010-10-01 | 2018-01-31 |
| Outcome Study of Highly-cross Linked Polyethylene vs. Standard Polyethylene for Primary Posterior Stabilized (PS) Total Knee knee arthroplasty, standard polyethylene, knee arthroplasty, XLP polyethylene - Arthroplasty, Replacement, Knee | Unknown | Chapel Hill Orthopedics Surgery & Sports Medicine | 500 | 2009-07-01 | 2017-02-01 |
Showing 20 of 27. Sign in to see all of them.
Osteolysis, Essential (5) · Multiple Myeloma (4) · Joint Diseases (3) · Osteoarthritis (3) · Arthritis (2) · Congenital Lipomatous Overgrowth, Vascular Malformations, and Epidermal Nevi (2) · Kaposiform Hemangioendothelioma (2) · Klippel-Trenaunay-Weber Syndrome (2) · Lymphatic Abnormalities (2) · Lymphatic Diseases (2) · Musculoskeletal Diseases (2) · Rheumatic Diseases (2) · Vascular Malformations (2) · Acro-Osteolysis (1)
Bone Diseases (27) · Bone Resorption (26) · Musculoskeletal Diseases (25) · Bone Diseases, Developmental (7) · Cardiovascular Diseases (7) · Hemic and Lymphatic Diseases (7) · Vascular Diseases (7) · Skin and Connective Tissue Diseases (6) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Connective Tissue Diseases (5) · Immune System Diseases (5) · Neoplasms (5) · Neoplasms by Histologic Type (5) · Blood Protein Disorders (4)
Arthroplasty, Replacement, Hip (2) · ARQ 197 (1) · Arthroplasty, Replacement, Knee (1) · Blood Specimen Collection (1) · Clodronic Acid (1) · Control Groups (1) · Denosumab (1) · Exercise (1) · Microscopic Angioscopy (1) · Zoledronic Acid (1)
Anderson Orthopaedic Research Institute (3) · Sahlgrenska University Hospital (2) · Aesculap AG (1) · Assiut University (1) · Bayer (1) · Boston Children's Hospital (1) · Chapel Hill Orthopedics Surgery & Sports Medicine (1) · Children's Hospital Medical Center, Cincinnati (1) · Children's Hospital of Philadelphia (1) · Encore Medical, L.P. (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Hadassah Medical Organization (1) · IC-MedTech Corporation (1) · Koite Health Oy (1) · Medical University of Lublin (1)
United States (14) · Denmark (2) · Germany (2) · Czechia (1) · Finland (1) · Israel (1) · Italy (1) · Poland (1) · Sweden (1)
C. Anderson Engh, Jr., MD (2) · Amanda Lynggaard Riis, Student (1) · Aneta A Szudy-Szczyrek, MD., PhD. (1) · Charles A. Engh, Sr., MD (1) · Daniel Grande, Ph.D. (1) · Ellen-Margrethe Hauge, Professor (1) · Frederik Cosedis Enevoldsen, Student (1) · Josephine Therkildsen, MD (1) · Katja Thorup Aaen, Student (1) · Leonid Kandel, MD (1) · Marco Spezia, MD (1) · Marilyn Liang, M.D. (1)
PMID 16950057, PMID 17823032, PMID 22210669, PMID 22682044, PMID 23666771, PMID 24252784, PMID 26388606, PMID 26610319, PMID 27108405, PMID 28595941, PMID 28782106, PMID 30805524, PMID 32220591, PMID 34430024, PMID 3591830, PMID 37927741, PMID 38340159, PMID 39246942, PMID 40200363, PMID 9561014
2014 (1), N01CM00039 (1), P30CA016672 (1), U01CA062461 (1)