30 unknown. 30 Phase 3, 10 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 30 | Unknown 30 |
| Phase 2 | 10 | Unknown 10 |
Follow Craniocerebral Trauma: new trials by email Literature Review of Craniocerebral Trauma trials Research Report on Craniocerebral Trauma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pilot Study of Whole Blood Transfusion for Trauma Brain Injury (TBI) Whole blood transfusion, Blood components transfusion - Traumatic Brain Injury | Phase 3 | Unknown | Oregon Health and Science University | 100 | 2024-08-01 | 2024-04-02 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis Adezunap, Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Role of Combined Therapy of Propranolol and Gabapentin in Paroxysmal Sympathetic Hyperactivity in Traumatic Brain Injury Propranolol , gabapentin - Traumatic Brain Injury | Phase 3 | Unknown | Zagazig University | 90 | 2022-12-01 | 2023-06-13 |
| Sedation of Ventilated Traumatic Brain Injury Patients With Midazolam Alone Versus Combination With Dexmedetomidine or Magnesium Sulfate; Monitored by Ultrasonograghic Optic Nerve Sheath Diameter Ultrasonograghic optic nerve sheath diameter US-ONSD, midazolam, dexmedetomidine - TBI (Traumatic Brain Injury) | Phase 3 | Unknown | Assiut University | 108 | 2022-11-01 | 2022-04-22 |
| Restart TICrH AP Pilot Trial Timing/1 week, Timing/3 weeks - Traumatic Intracranial Hemorrhage | Phase 3 | Unknown | University of Texas at Austin | 100 | 2022-10-01 | 2021-10-07 |
| Effect of Intravenous Methylprednisolone and Intravenous Erythropoietin in Toxic Optic Neuropathies: Randomized Clinical Trial. Recombinant human erythropoietin 4,000 UI and 2,000 UI, Methylprednisolone succinate 500 mg - Toxic Optic Neuropathy, Treatment | Phase 2 / Phase 3 | Unknown | Asociación para Evitar la Ceguera en México | 18 | 2022-04-05 | 2023-02-28 |
| 3D Printed Titanium Mesh vs Guided Autogenous Graft orbital floor recontriction - Orbital Floor (Blow-Out) Open Fracture, Enophthalmos Traumatic | Phase 2 / Phase 3 | Unknown | Mohammed Ghassan Mohammed Shaalan | 32 | 2021-09-01 | 2022-09-22 |
| Interventions for Convergence Insufficiency in Concussed Children Standard Community Concussion Care (SC), SC plus Simple Convergence Exercises (SC+), SC plus Office-based Vergence/Accommodative Therapy (SC+OBVAT) - Concussion, Convergence Insufficiency | Phase 3 | Unknown | Mitchell Scheiman | 264 | 2021-04-01 | 2020-10-23 |
| COMPARATIVE ANALYSIS OF INNOVATIVE BONE HEALING TECHNIQUES autograft, autograft with addition of concenterated growth factor, xenograft with concentrated growth factor - To Assess the Bone Healing in Fracture Mandible Defects | Phase 2 / Phase 3 | Unknown | Dow University of Health Sciences | 60 | 2020-12-17 | 2022-07-29 |
| Efficacy of Atorvastatin in Chronic Subdural Haematoma Atorvastatin 20mg, Placebos - Chronic Subdural Hematoma | Phase 3 | Unknown | Chinese University of Hong Kong | 690 | 2020-01-09 | 2021-11-22 |
| Study on Clinical Effectiveness of L-Oxiracetam Injection Test group: L-oxiracetam Injection, Control group: Oxiracetam Injection, Placebo group: Placebo Injection - Craniocerebral Injury | Phase 3 | Unknown | Nanjing Yoko Biomedical Co., Ltd. | 591 | 2019-09-30 | 2024-02-15 |
| Tranexamic Acid in the Treatment of Residual Chronic Subdural Hematoma Tranexamic Acid 500 MG - Chronic Subdural Hematoma | Phase 3 | Unknown | Unity Health Toronto | 60 | 2017-03-06 | 2017-09-14 |
| Mgt of Chronic Subdural Hematoma Using Dexamethasone Dexamethasone, Any surgical intervention aim at treating chronic subdural hematoma - Chronic Subdural Hematoma | Phase 2 / Phase 3 | Unknown | University of Calgary | 326 | 2016-09-17 | 2020-07-01 |
| Treatment of Corneal Abrasions With Topical Tetracaine Ophthalmic Tetracaine, Normal Saline - Corneal Abrasion | Phase 2 / Phase 3 | Unknown | New York Presbyterian Brooklyn Methodist Hospital | 120 | 2016-06-01 | 2016-05-13 |
| Neuromonitoring in Patients During Aortic Valve Replacement Transcranial doppler - Brain Injury | Phase 3 | Unknown | Marija Bozhinovska | 60 | 2016-01-01 | 2016-10-28 |
| Asia Coma Electrical Stimulation (the ACES Trial) Right median nerve stimulation - TBI (Traumatic Brain Injury) | Phase 3 | Unknown | RenJi Hospital | 360 | 2016-01-01 | 2016-01-01 |
| Pre-hospital Administration of Tranexamic Acid for Moderate and Severe Traumatic Brain Injury Tranexamic Acid, Sodium chloride - Brain Injuries, Traumatic | Phase 3 | Unknown | RenJi Hospital | 400 | 2016-01-01 | 2016-01-01 |
| Tranexamic Acid in Chronic Subdural Hematomas Tranexamic Acid, Placebo - Chronic Subdural Hematoma | Phase 2 / Phase 3 | Unknown | Centre de recherche du Centre hospitalier universitaire de Sherbrooke | 130 | 2015-11-01 | 2023-09-05 |
| Hyperbaric Oxygen Treatment to Treat Mild Traumatic Brain Injury (mTBI)/Persistent Post-Concussion Syndrome (PPCS) Hyperbaric Oxygen, No Hyperbaric Oxygen - Post-Concussion Syndrome, Traumatic Brain Injury | Phase 3 | Unknown | Louisiana State University Health Sciences Center in New Orleans | 59 | 2014-05-01 | 2017-04-18 |
Showing 20 of 30. Sign in to see all of them.
Brain Injuries, Traumatic (11) · Hematoma, Subdural, Chronic (5) · Brain Concussion (3) · Brain Injuries (3) · Agnosia (2) · Chronic Pain (2) · Eye Burns (2) · Marijuana Abuse (2) · Multiple Sclerosis (2) · Neuralgia (2) · Pain (2) · Paraplegia (2) · Phantom Limb (2) · Post-Concussion Syndrome (2)
Nervous System Diseases (30) · Trauma, Nervous System (30) · Wounds and Injuries (29) · Brain Diseases (20) · Central Nervous System Diseases (20) · Brain Injuries (11) · Pathological Conditions, Signs and Symptoms (10) · Cardiovascular Diseases (9) · Cerebrovascular Disorders (9) · Pathologic Processes (9) · Vascular Diseases (9) · Facial Injuries (6) · Hemorrhage (6) · Intracranial Hemorrhages (6)
Tranexamic Acid (3) · Magnesium Sulfate (2) · Sodium Chloride (2) · Atorvastatin (1) · Calcium Dobesilate (1) · Chlortetracycline (1) · Conservative Treatment (1) · Control Groups (1) · Dexamethasone (1) · Dexmedetomidine (1) · Doxycycline (1) · Exchange Transfusion, Whole Blood (1) · Gabapentin (1) · Hyperbaric Oxygenation (1) · Melatonin (1)
Apurano Pharmaceuticals GmbH (2) · RenJi Hospital (2) · University of Calgary (2) · Asociación para Evitar la Ceguera en México (1) · Assiut University (1) · Centre de recherche du Centre hospitalier universitaire de Sherbrooke (1) · Chinese University of Hong Kong (1) · Dow University of Health Sciences (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium (1) · Kwong Wah Hospital (1) · Louisiana State University Health Sciences Center in New Orleans (1) · Marija Bozhinovska (1) · Ministry of Health, Malaysia (1) · Mitchell Scheiman (1)
Canada (5) · United States (5) · China (4) · Egypt (2) · Germany (2) · Bolivia (1) · Ecuador (1) · France (1) · Hong Kong (1) · Iran (1) · Malaysia (1) · Mexico (1) · Pakistan (1) · Slovenia (1)
Alireza Baradaran Raffiee, MD (1) · Andrew W Howard, MD, MSc (1) · Borut Gersak, MD, PhD (1) · Dan Liang, MD (1) · David Mathieu, M.D. (1) · Essamedin Negm, MD (1) · Guoyi Gao (1) · Guoyi Gao, MD, PhD (1) · Heba Mohamed Kamel, Assistant Professor (1) · Jiyao Jiang (1) · Junfeng Feng (1) · Karen M Barlow, MB.ChB (1)
PMID 20554319, PMID 23234472, PMID 24672709, PMID 24731434, PMID 27150916, PMID 28693604, PMID 32189664, PMID 32217739, PMID 32772826, PMID 34030698, PMID 35622535, PMID 37178149, PMID 38975302, PMID 41381424, PMID 42104241
R01HD021453 (1), R01NS058302 (1)