197 completed, 72 unknown, 34 recruiting, 24 terminated. 142 Not applicable, 41 Phase 4, 31 Phase 3, 21 Phase 2, 6 Phase 1.
Follow Coronary Stenosis: new trials by email Literature Review of Coronary Stenosis trials Research Report on Coronary Stenosis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rapid Inflation/Deflation Compared With Prolonged High-Pressure Balloon Inflation Prolonged inflation, Rapid inflation - Coronary Artery Disease, Coronary Stent Occlusion | Not applicable | Not yet recruiting | Central Arkansas Veterans Healthcare System | 40 | 2027-01-01 | 2026-10-21 |
| Coronary Laser Atherectomy System for Treatment of Coronary Artery Stenosis (SHINE) Coronary Laser Atherectomy System, CVX300 Laser System - Coronary Artery Stenosis | Not applicable | Not yet recruiting | Shanghai MicroPort Rhythm MedTech Co., Ltd. | 218 | 2026-11-10 | 2026-08-07 |
| Brazilian Prospective Registry of the Inspiron EVO Drug-Eluting Stent in Complex Coronary Lesions Inspiron EVO Drug-Eluting Stent - Coronary Artery Disease (CAD), Stenosis Coronary | Recruiting | Scitech Produtos Medicos SA | 2000 | 2026-10-30 | 2026-10-02 | |
| The PICCOLETO XIII REVEAL-DCB Cohort A Study Coronary Artery Disease, Coronary Stenosis | Not yet recruiting | Fondazione Ricerca e Innovazione Cardiovascolare ETS | 200 | 2026-10-01 | 2026-10-09 | |
| Multimodality Optical and Ultrasound Intravascular Imaging for Stent Optimization and Atheroma Assessment Conavi Medical Novasight Hybrid System intervention - Coronary Artery Disease, Coronary Stenosis | Not applicable | Withdrawn | Barts & The London NHS Trust | 2026-09-01 | 2025-09-17 | |
| First-in-Human Study Using the SiroMax™ Sirolimus-Coated Balloon Catheter as a Percutaneous Transluminal Coronary Angioplasty (PTCA) Balloon Catheter to Treat Subjects Who Have Coronary Artery Disease (CAD) Involving In-Stent Restenosis (ISR) or an Unstented Lesion in a Small Coronary Vessel (DNSV). Sirolimus-coated balloon catheter - Coronary Artery Disease, Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)) | Not applicable | Recruiting | Tonic Medical, Inc. | 60 | 2026-08-12 | 2026-09-14 |
| Evaluate the Clinical Efficacy and Safety of Non-Compliant PTCA Balloon Dilatation Catheter balloon angioplasty - Coronary Artery Stenosis, Coronary Artery Disease | Completed | TEDA International Cardiovascular Hospital | 200 | 2026-07-01 | 2026-10-16 | |
| QFR-Guided Virtual Stenting for Preprocedural Physiological Optimization of Percutaneous Coronary Intervention: A Randomized Controlled Trial Virtual Stenting-Guided PCI Optimization, Standard Angiography-Guided PCI - Coronary Artery Disease, Coronary Stenosis | Not applicable | Recruiting | China National Center for Cardiovascular Diseases | 1472 | 2026-06-02 | 2026-07-06 |
| AI-Enhanced Single-Lead ECG Screening for Coronary Stenosis single-channel electrocardiogram - Ischemic Heart Disease, Coronary Artery Stenosis | Not yet recruiting | I.M. Sechenov First Moscow State Medical University | 400 | 2026-05-01 | 2026-05-12 | |
| Artificial Intelligence-Driven Medipixel Fractional Flow Reserve Versus Invasive Fractional Flow Reserve-Guided PCI Trial (AIM-FFR Trial) MPFFR or Invasive FFR - Coronary Artery Disease, Chronic Coronary Syndrome | Not applicable | Recruiting | Samsung Medical Center | 2100 | 2026-03-18 | 2026-04-23 |
| Clinical Evaluation of Radiation Reduction for Optimized Safety Coronary Artery Disease, Myocardial Infarction | Not yet recruiting | Angiowave Imaging | 50 | 2026-02-15 | 2025-11-13 | |
| Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO IV-EPIC 38) Drug-coated balloon, Single antiplatelet therapy (SAPT), Dual antiplatelet therapy (DAPT) - Coronary Disease, Heart Diseases | Not applicable | Recruiting | Fondazione Ricerca e Innovazione Cardiovascolare ETS | 576 | 2026-01-10 | 2026-01-22 |
| Reconstruction of Diffusely Diseased Left Anterior Descending with Left Internal Mammary Artery On-lay Patch or Saphenous Vein Patch Without Endarterectomy by Opening the Whole Wall of the Diseased Segment(s) Has Less Risk and Fewer Complications Compared to Endarterectomy Technique CABG, LIMA on lay patch, Safenous vein patch - LAD (Left Anterior Descending) Coronary Artery Stenosis | Not applicable | Not yet recruiting | Assiut University | 90 | 2025-12-10 | 2025-02-19 |
| Disease Characteristics of R-CAD Protocol-defined Examinations and Evaluations - Coronary Artery Disease, Coronary Artery Disease Progression | Not yet recruiting | Peking Union Medical College Hospital | 52 | 2025-11-01 | 2025-11-28 | |
| PCI Registry Basel Coronary Artery Disease, Coronary Stenosis | Recruiting | University Hospital, Basel, Switzerland | 10000 | 2025-10-01 | 2026-09-10 | |
| Impact of Cholesterol Level on Long-term Coronary Bypass Graft Patency Computed tomography coronary angiogram - Coronary Artery Disease, Bypass Graft Stenosis | Withdrawn | Chinese University of Hong Kong | 2025-09-01 | 2025-03-06 | ||
| To Evaluate the Performance and Safety of RisoR Crest Everolimus Eluting Coronary Stent System Coronary Stent - Coronary Artery Disease, Coronary Artery Stenosis | Not applicable | Not yet recruiting | Poly Medicure Limited | 2000 | 2025-08-18 | 2025-08-01 |
| IonMAN II Trial- Early Feasibility Study of the IoNIR Ridaforolimus-Eluting Coronary Stent System IoNIR Ridaforolimus-Eluting Coronary Stent System - Coronary Stenosis, Coronary Artery Disease | Not applicable | Suspended | Medinol Ltd. | 30 | 2025-08-07 | 2026-10-09 |
| Restrospective Analysis of MACE in Patients Treated With Drug-elluting Balloons. DEB - Coronary Arterial Disease (CAD), Restenosis, Coronary | Recruiting | Olivier F. Bertrand | 1500 | 2025-06-10 | 2026-04-20 | |
| Wearable Devices Assist in the Detection, Screening, and Management of Major Diseases in Middle-aged and Elderly Populations Smartwatch + GP, GP only - Coronary Stenosis, Cerebral Arterial Diseases | Not applicable | Not yet recruiting | Tongji Hospital | 800 | 2025-06-01 | 2025-05-20 |
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Coronary Artery Disease (198) · Coronary Restenosis (107) · Myocardial Ischemia (70) · Coronary Disease (65) · Vascular Diseases (32) · Angina Pectoris (26) · Cardiovascular Diseases (21) · Myocardial Infarction (21) · Acute Coronary Syndrome (18) · Angina, Unstable (18) · Coronary Occlusion (15) · Angina, Stable (14) · Atherosclerosis (14) · Heart Diseases (11)
Heart Diseases (357) · Cardiovascular Diseases (347) · Vascular Diseases (336) · Coronary Disease (303) · Myocardial Ischemia (298) · Arterial Occlusive Diseases (202) · Arteriosclerosis (199) · Pathological Conditions, Signs and Symptoms (79) · Pathologic Processes (48) · Neurologic Manifestations (45) · Pain (45) · Signs and Symptoms (45) · Chest Pain (39) · Infarction (30)
Percutaneous Coronary Intervention (24) · Tomography, Optical Coherence (6) · Drug-Eluting Stents (4) · Angioplasty, Balloon (3) · Aspirin (3) · Clopidogrel (3) · Iopamidol (3) · Sirolimus (3) · Angiography (2) · Coronary Artery Bypass (2) · Exercise Test (2) · Fractional Flow Reserve, Myocardial (2) · Immunosuppression Therapy (2) · Pioglitazone (2) · Secondary Prevention (2)
Abbott Medical Devices (45) · Seung-Jung Park (12) · Medinol Ltd. (7) · Cardio Med Medical Center (6) · Seoul National University Hospital (6) · China National Center for Cardiovascular Diseases (5) · Biotronik AG (4) · Copenhagen University Hospital, Rigshospitalet (4) · Deutsches Herzzentrum Muenchen (4) · Foundation of Cardiovascular Research and Education Enschede (4) · Meshalkin Research Institute of Pathology of Circulation (4) · Peking Union Medical College Hospital (4) · Samsung Medical Center (4) · Biosensors Europe SA (3) · Bracco Diagnostics, Inc (3)
United States (73) · Germany (55) · Netherlands (48) · China (40) · France (40) · South Korea (34) · Italy (32) · United Kingdom (26) · Belgium (25) · Switzerland (25) · Spain (24) · Canada (23) · Denmark (21) · Poland (21) · Australia (17)
Gregg W Stone, MD (6) · Patrick Serruys, MD (4) · Alexandre Abizaid, MD (3) · Bon-Kwon Koo, MD, PhD (3) · Bruno Scheller, MD (3) · James Hermiller, MD (3) · Joo Myung Lee, MD, MPH, PhD (3) · Maarten J. Suttorp, MD, PhD (3) · Mitch Krucoff, MD (3) · Zhenyu Liu, M.D. (3) · A. Pieter Kappetein, MD (2) · Antonio Colombo, MD (2) · Aram Salzman (2) · Ashok Seth, MD (2) · Bon-kwon Koo, MD/PhD (2)
PMID 25940520, PMID 24746650, PMID 26825231, PMID 29089314, PMID 31561250, PMID 35641327, PMID 37619976, PMID 37745109, PMID 22017936, PMID 22115661, PMID 26585622, PMID 15893169, PMID 17101615, PMID 18082503, PMID 18307999, PMID 18536865, PMID 19737719, PMID 20442358, PMID 21232715, PMID 21232716, PMID 22440499, PMID 27418609, PMID 33893022, PMID 34666500, PMID 34717627, PMID 37675090, PMID 38598970, PMID 39959922, PMID 40687396, PMID 10392863, PMID 10694523, PMID 10898458, PMID 11231434, PMID 11368702, PMID 12742284, PMID 12851627, PMID 15302787, PMID 15500897, PMID 16160130, PMID 16267256, PMID 16286182, PMID 16287955, PMID 16444619, PMID 16531618, PMID 16949496, PMID 17261663, PMID 17353456, PMID 17387127, PMID 17470709, PMID 17478137
2008 (1), 2016 (1), 2019 (1), R01HL111141 (1), ZIAHL006138 (1)