22 unknown. 22 Phase 3, 10 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 22 | Unknown 22 |
| Phase 2 | 10 | Unknown 10 |
Follow Cardiovascular Abnormalities: new trials by email Literature Review of Cardiovascular Abnormalities trials Research Report on Cardiovascular Abnormalities
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| " Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD " Sacubitril 49 MG / Valsartan 51 MG [Entresto] BID, Empagliflozin 10 MG OD - Congenital Heart Disease, Heart Failure | Phase 2 / Phase 3 | Unknown | Instituto Nacional de Cardiologia Ignacio Chavez | 160 | 2023-02-06 | 2022-11-02 |
| PAIR (Paracetamol and Ibuprofen Research) Pilot Trial Paracetamol injection, Ibuprofen injection - Patent Ductus Arteriosus | Phase 2 / Phase 3 | Unknown | Manchester University NHS Foundation Trust | 32 | 2021-09-03 | 2023-10-30 |
| Training in Exercise Activities and Motion for Growth (TEAM 4 Growth) RCT passive range of motion exercise therapy - Congenital Heart Disease | Phase 3 | Unknown | Carelon Research | 144 | 2021-02-23 | 2024-07-03 |
| Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression - The PLICTS Study Rivaroxaban, Warfarin, Nadroparin - May-Thurner Syndrome | Phase 3 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 224 | 2020-05-18 | 2024-04-18 |
| Alternative Paracetamol Treatments for the Neonate With a hsPDA Rectal Solution, Intravenous Infusion - Ductus Arteriosus, Patent | Phase 2 / Phase 3 | Unknown | Shaare Zedek Medical Center | 80 | 2018-09-01 | 2018-07-30 |
| Efficacy and Safety of Rapamycin to Complex Vascular Anomalies in Pediatric Patients Treatment with oral rapmycin - Vascular Anomalies | Phase 2 / Phase 3 | Unknown | Zhujiang Hospital | 30 | 2017-12-01 | 2021-11-10 |
| Treatment of Congenital Vascular Malformations Using Sirolimus: Improving Quality of Life Sirolimus - Vascular Malformations | Phase 3 | Unknown | Radboud University Medical Center | 75 | 2017-09-18 | 2021-01-29 |
| Treatment of Nasal Staphylococcus Aureus Colonization in Patients With HHT Mupirocin, Placebo - Hereditary Hemorrhagic Telangiectasia, Epistaxis | Phase 3 | Unknown | Hospital Italiano de Buenos Aires | 40 | 2017-06-01 | 2016-11-15 |
| Clinical Trial to Evaluate Two Guidelines for the Administration of Ibuprofen in the Treatment of Persistent Ductus Arteriosus Eco-guided: Impact in the Intestinal Prognosis Ibuprofen in continuous (24 hours) iv infusion and EchoG, IV bolus Ibuprofen slow (15 minutes) and EchoG - Persistent Ductus Arteriosus | Phase 3 | Unknown | Instituto de Investigación Hospital Universitario La Paz | 180 | 2017-02-20 | 2020-10-29 |
| Heartflow (AFFECTS) FFRct and SPECT - Cardiovascular Abnormalities | Phase 3 | Unknown | Baylor Research Institute | 270 | 2016-09-01 | 2022-03-18 |
| Follow-up Safety Trial in Children With Chronic Heart Failure Therapy Receiving Orodispersible Minitablets of Enalapril Enalapril Orodispersible Minitablet - Heart Failure, Dilated Cardiomyopathy | Phase 2 / Phase 3 | Unknown | Ethicare GmbH | 100 | 2016-03-01 | 2016-01-13 |
| Orodispersible Minitablets of Enalapril in Young Children With Heart Failure Due to Congenital Heart Disease Enalapril Orodispersible Minitablet - Heart Failure, Congenital Heart Disease | Phase 2 / Phase 3 | Unknown | Ethicare GmbH | 50 | 2016-01-01 | 2016-01-12 |
| Goal Directed Hemodynamic Management of Acute Heart Failure After Cardiac Surgery in Children Goal directed therapy, Control - Cardiac Surgery | Phase 3 | Unknown | Meshalkin Research Institute of Pathology of Circulation | 40 | 2015-12-01 | 2015-12-18 |
| Indicated Prevention With Long-chain Polyunsaturated Omega-3 Fatty Acids in Patients With 22q11 Microdeletion Syndrome. omega-3 PUFAs, Standard care, placebo - 22q11 Deletion Syndrome | Phase 2 / Phase 3 | Unknown | Bambino Gesù Hospital and Research Institute | 80 | 2014-06-01 | 2014-02-25 |
| Multi-center Trial of Percutaneous Pulmonary Valve Implantation With Venus-p Venues-P Valve - Pulmonary Regurgitation, Tetralogy of Fallot | Phase 2 / Phase 3 | Unknown | Shanghai Zhongshan Hospital | 44 | 2013-05-01 | 2015-10-29 |
| Functional Magnetic Resonance Imagine(fMRI)Navigation in Intracranial Arteriovenous Malformation Surgery fMRI Navigation AVM resection, conventional resection - Intracranial Arteriovenous Malformations | Phase 3 | Unknown | Beijing Tiantan Hospital | 600 | 2013-01-01 | 2013-03-04 |
| Hybrid Versus Norwood Management Strategies in Infants Undergoing Single Ventricle Palliation Norwood management strategy, Hybrid Strategy - Congenital Heart Disease | Phase 3 | Unknown | The Hospital for Sick Children | 50 | 2010-03-01 | 2010-05-31 |
| Application of Neurally Adjusted Ventilatory Assist to Children After Congenital Cardiac Surgery mode of neurally adjusted ventilatory assist, Mode of pressure support ventilation - Mechanical Ventilation Complication, Congenital Heart Disease | Phase 3 | Unknown | Shanghai Jiao Tong University School of Medicine | 72 | 2010-01-01 | 2012-08-10 |
| Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome Losartan, Atenolol - Marfan Syndrome | Phase 3 | Unknown | Forteza, Albert, M.D. | 140 | 2008-10-01 | 2010-08-12 |
| Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients Losartan and nebivolol, Losartan, Nebivolol - Marfan Syndrome | Phase 3 | Unknown | Fondazione IRCCS Policlinico San Matteo di Pavia | 291 | 2008-07-01 | 2011-07-22 |
Showing 20 of 22. Sign in to see all of them.
Heart Defects, Congenital (7) · Ductus Arteriosus, Patent (3) · Heart Failure (3) · Foramen Ovale, Patent (2) · Heart Septal Defects, Atrial (2) · Marfan Syndrome (2) · Vascular Malformations (2) · 22q11 Deletion Syndrome (1) · Camurati-Engelmann Syndrome (1) · Cardiomyopathy, Dilated (1) · Epilepsy (1) · Epistaxis (1) · Headache (1) · Hereditary Sensory and Autonomic Neuropathies (1)
Cardiovascular Diseases (22) · Congenital Abnormalities (22) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (22) · Heart Diseases (16) · Heart Defects, Congenital (9) · Genetic Diseases, Inborn (5) · Nervous System Diseases (4) · Vascular Diseases (4) · Abnormalities, Multiple (3) · Brain Diseases (3) · Central Nervous System Diseases (3) · Musculoskeletal Diseases (3) · Vascular Malformations (3) · Bone Diseases (2)
Acetaminophen (2) · Ibuprofen (2) · Infusions, Intravenous (2) · Losartan (2) · Atenolol (1) · BID protein, human (1) · Early Goal-Directed Therapy (1) · Fish Oils (1) · Mupirocin (1) · Nadroparin (1) · Nebivolol (1) · Ointments (1) · Rivaroxaban (1) · Sirolimus (1) · Standard of Care (1)
Ethicare GmbH (2) · NMT Medical (2) · Bambino Gesù Hospital and Research Institute (1) · Baylor Research Institute (1) · Beijing Tiantan Hospital (1) · Carelon Research (1) · Fondazione IRCCS Policlinico San Matteo di Pavia (1) · Forteza, Albert, M.D. (1) · Hospital Italiano de Buenos Aires (1) · Instituto Nacional de Cardiologia Ignacio Chavez (1) · Instituto de Investigación Hospital Universitario La Paz (1) · Manchester University NHS Foundation Trust (1) · Meshalkin Research Institute of Pathology of Circulation (1) · Radboud University Medical Center (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1)
China (5) · United States (4) · Netherlands (3) · United Kingdom (3) · Austria (2) · Canada (2) · Hungary (2) · Serbia (2) · Spain (2) · Argentina (1) · Holy See (1) · Israel (1) · Italy (1) · Mexico (1) · Russia (1)
Christoph Male, Prof,MD,PhD (2) · Ida Jovanovic, Prof,MD,PhD (2) · Mark Reisman, MD (2) · Michael Burch, Prof,MD,PhD (2) · Michiel Dalinghaus, MD,PhD (2) · Alberto Forteza, Dr (1) · Anthony Furlan, MD (1) · Arin Mukherjee, MRCPCH (1) · Arturo Evangelista, Dr (1) · Carlos Guizar-Sanchez, MD (1) · Cathy Hammerman, MD (1) · Christopher Caldarone (1) · David Brown, MD (1) · Edgar Garcia-Cruz, MD (1)
PMID 16601194, PMID 17188619, PMID 17911499, PMID 19430350, PMID 21051670, PMID 22417252, PMID 23796341, PMID 24824357, PMID 25147037, PMID 25341453, PMID 27367242, PMID 29547081, PMID 30520545, PMID 31379715, PMID 32865377, PMID 32993773, PMID 33186500, PMID 33447845, PMID 33832352, PMID 37153086, PMID 41550606
2015 (2), 2016 (2)