37 completed, 6 unknown, 4 terminated, 2 recruiting. 17 Not applicable, 14 Phase 4, 8 Phase 2, 8 Phase 3, 3 Phase 1.
Follow Mupirocin: new trials by email Literature Review of Mupirocin trials Research Report on Mupirocin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Thermosensitive Gel Nasal Spray With Stem Cell Exosomes, Mupirocin, and DNase I for Chronic Sinusitis Exosomes (hUC-MSC-Exo), Mupirocin, DNase I - Chronic Rhinosinusitis With Nasal Polyps | Early Phase 1 | Not yet recruiting | The First Affiliated Hospital of Xinxiang Medical College | 108 | 2026-07-01 | 2026-06-09 |
| Decolonization Efficacy of Polyhexanide vs. Mupirocin Polyhexanide, Mupirocin and Chlorhexidine - Staphylococcus Aureus, Colonization, Asymptomatic | Phase 4 | Completed | Swiss Paraplegic Research, Nottwil | 24 | 2025-05-01 | 2026-07-08 |
| Bacterial Decolonization Within Dyads Mupirocin, Chlorhexidine baths - Bacterial Colonization | Not applicable | Completed | Duke University | 1 | 2024-08-21 | 2026-06-03 |
| Staph Intervention for Effective Local Defense Mupirocin + Nozin + chlorhexidine gluconate, Education + Household supplies - Staphylococcus Aureus Infection | Phase 4 | Completed | Johns Hopkins Bloomberg School of Public Health | 78 | 2024-04-01 | 2026-06-12 |
| Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study Mupirocin (50 mg), Mupirocin (500 mg), blood samples after Single dose part - Healthy, Staphylococcus Aureus Infection | Phase 1 | Active not recruiting | Centre Hospitalier Universitaire de Saint Etienne | 40 | 2024-02-29 | 2025-07-03 |
| Efficacy of Hydrocolloid Dressing vs. Topical Antibiotic on Wound Healing of Post-Punch Biopsy Wounds Mupirocin (drug), Hydrocolloid Dressing (DuoDERM CGF) - Biopsy Wound | Not applicable | Completed | University of Santo Tomas Hospital, Philippines | 60 | 2024-01-29 | 2025-08-24 |
| Mupirocin 2% Ointment Vs Spray Antibiotics on Temporary Hemodialysis Catheter Local antibiotic spray Neomycin sulphate 165,000 IU + Bacitracin zinc 12,500 IU, Mupirocin 2% ointment - Hemodialysis Complication, Hemodialysis Catheter Infection | Phase 2 / Phase 3 | Completed | Future University in Egypt | 150 | 2023-04-10 | 2023-08-22 |
| The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal Chlorhexidine gluconate (4%), Mupirocin 2% Ointment - Surgical Wound Infection | Phase 3 | Recruiting | The Cooper Health System | 848 | 2023-03-13 | 2025-08-26 |
| Decolonization to Reduce After-Surgery Events of Surgical Site Infection 4% Chlorhexidine Gluconate, 2% Mupirocin, Soap Without Antiseptic Properties (Placebo) - Surgical Site Infection | Phase 4 | Recruiting | University of California, Irvine | 2700 | 2023-01-17 | 2026-07-21 |
| Effects of Topical Gentamicin on the Prevention of Peritoneal Dialysis Related Infection Mupirocin, Gentamicin - Peritoneal Dialysis-related Infection | Not applicable | Unknown | Phramongkutklao College of Medicine and Hospital | 60 | 2021-12-01 | 2022-02-22 |
| To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Secondarily Infected Traumatic Skin Lesions Mupirocin Calcium, Vehicle - Secondarily Infected Traumatic Skin Lesions | Phase 3 | Completed | Padagis LLC | 657 | 2019-10-15 | 2022-11-03 |
| Topical Antibiotics in Chronic Rhinosinusitis Mupirocin, Tobramycin, Levofloxacin - Chronic Rhinosinusitis (Diagnosis) | Phase 1 / Phase 2 | Completed | Mayo Clinic | 19 | 2018-09-26 | 2022-04-20 |
| STaph Aureus Resistance-Treat Early and Repeat (STAR-TER) Trimethoprim Sulfamethoxazole (TMP/SMX), Minocycline, Mupirocin - Cystic Fibrosis | Phase 2 | Completed | University of North Carolina, Chapel Hill | 49 | 2018-04-03 | 2026-09-15 |
| Comparison of Topical Therapies in Post op Endoscopic Sinus Surgery Patients Saline Nasal, Budesonide Nasal, Topical Antibacterial (Product) - Chronic Rhinosinusitis (Diagnosis) | Phase 3 | Withdrawn | University of Florida | 2018-04-01 | 2018-03-30 | |
| S. Aureus Decolonization in HPN Patients. Doxycycline, Trimethoprim, Sulfamethoxazole/trimethoprim - Staphylococcus Aureus, Motility Disorder | Not applicable | Terminated | Radboud University Medical Center | 63 | 2018-02-08 | 2022-05-31 |
| Treatment of Nasal Staphylococcus Aureus Colonization in Patients With HHT Mupirocin, Placebo - Hereditary Hemorrhagic Telangiectasia, Epistaxis | Phase 3 | Unknown | Hospital Italiano de Buenos Aires | 40 | 2017-06-01 | 2016-11-15 |
| Preoperative Decolonization and Surgical Site Infections - a Prospective Randomized Trial Mupirocin 2% nasal ointement, Chlorhexidine sol 4% - Orthopedic Disorders, Surgical Site Infection | Not applicable | Completed | Lindenhofgruppe AG | 1300 | 2015-11-01 | 2018-02-27 |
| Patient-Centered Comparative Effectiveness Research (CER) Study of Home-based Interventions to Prevent CA-MRSA Infection Recurrence 2% mupirocin ointment, Chlorhexidine wash, Hygiene protocol - Methicillin-Resistant Staphylococcus Aureus, Recurrence | Phase 4 | Unknown | Clinical Directors Network | 278 | 2015-10-01 | 2017-07-21 |
| Staph Household Intervention for Eradication (SHINE) Chlorhexidine, Mupirocin, Household cleaning - Skin and Subcutaneous Tissue Bacterial Infections, Staphylococcus Aureus | Phase 4 | Completed | Washington University School of Medicine | 835 | 2015-10-01 | 2026-02-24 |
| Treating Parents to Reduce NICU Transmission of Staphylococcus Aureus Trial Mupirocin and Chlorhexidine, Placebo ointment and placebo cloths - Staph Aureus Colonization, Staph Aureus Infection | Not applicable | Completed | Johns Hopkins University | 307 | 2014-11-01 | 2022-01-11 |
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Staphylococcal Infections (20) · Surgical Wound Infection (6) · Abscess (5) · Impetigo (4) · Staphylococcal Skin Infections (4) · Cellulitis (3) · Cystic Fibrosis (3) · Furunculosis (3) · Infections (3) · Disease (2) · Asymptomatic Infections (1) · Critical Illness (1) · Cross Infection (1) · Dermatitis, Atopic (1) · Digestive System Diseases (1)
Washington University School of Medicine (4) · Johns Hopkins University (3) · GlaxoSmithKline (2) · University of North Carolina, Chapel Hill (2) · Ann & Robert H Lurie Children's Hospital of Chicago (1) · B. Braun Medical SA (1) · Brooke Army Medical Center (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Chikara Tashiro (1) · Children's Hospital of Philadelphia (1) · Clinical Directors Network (1) · Destiny Pharma Plc (1) · Duke University (1) · Endeavor Health (1) · Future University in Egypt (1)
United States (32) · Philippines (2) · Spain (2) · Switzerland (2) · Argentina (1) · Canada (1) · Denmark (1) · Egypt (1) · France (1) · Germany (1) · Hong Kong (1) · Israel (1) · Japan (1) · Netherlands (1) · South Africa (1)
Stephanie A Fritz, MD, MSCI (2) · Aaron Milstone, MD, MHS (1) · Albert C. Yan, MD (1) · Almena L Free, MD (1) · Amy Paller, MD (1) · Bernard C. Camins, MD, MSCR (1) · Chris Goss, MD (1) · Christof von Eiff, MD (1) · Craig D Brown, BSc (Med), MD, FRCSC, FACS (1) · Daraporn Rungprai, BCP (1) · David Seligson, MD (1) · Deborah Yokoe, MD, MPH (1) · Doaa ElBohy, PhD (1) · Eli N. Perencevich, MD MS BS (1)
PMID 36511181, PMID 15276398, PMID 15840453, PMID 18702902, PMID 19128645, PMID 19403473, PMID 19588358, PMID 21828967, PMID 22033452, PMID 22198793, PMID 22311838, PMID 22530208, PMID 22980682, PMID 23776108, PMID 23796939, PMID 24119597, PMID 25239721, PMID 25832968, PMID 26018036, PMID 26353875, PMID 26363164, PMID 26380335, PMID 27440128, PMID 27466854, PMID 27492790, PMID 27556896, PMID 27852955, PMID 28124652, PMID 29954418, PMID 30587533, PMID 31737738, PMID 31886828, PMID 32521007, PMID 33618788, PMID 35342110, PMID 36925849, PMID 36965196, PMID 37471087, PMID 4902833, PMID 8948280
S06GM142120 (1)