97 completed, 57 unknown, 43 recruiting, 18 terminated. 59 Not applicable, 46 Phase 2, 26 Phase 1, 22 Phase 3, 9 Phase 4.
Follow Cardiomyopathy, Dilated: new trials by email Literature Review of Cardiomyopathy, Dilated trials Research Report on Cardiomyopathy, Dilated
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BAG3-DCM Natural History Study Dilated Cardiomyopathy (DCM), Cardiovascular Diseases | Not yet recruiting | Rocket Pharmaceuticals Inc. | 30 | 2026-12-01 | 2026-10-19 | |
| An AAV Gene Therapy Trial of AFTX-201 in Adults With BAG3-Associated Dilated Cardiomyopathy (DCM) AFTX-201 - Dilated Cardiomyopathy (DCM), BAG3 Mutation Associated Dilated Cardiomyopathy | Phase 1 / Phase 2 | Recruiting | Affinia Therapeutics | 22 | 2026-10-01 | 2026-10-21 |
| Observational Study of Natural History of BAG3 Gene Mutation-Associated Dilated Cardiomyopathy in Chinese Adults Observational, None intervention - Dilated Cardiomyopathy | Recruiting | AstraZeneca | 10 | 2026-08-18 | 2026-10-22 | |
| RHYthm and Myocardial Function Relationship Evaluation in Heart Diseases speckle tracking echocardiography - Arrhythmia, Cardiomyopathy, Dilated | Recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 253 | 2026-06-23 | 2026-09-10 | |
| A Study With NVC-001 in Patients With LMNA-related Dilated Cardiomyopathy (SUNBEAM-LMNA) NVC-001 - Low Dose, NVC-001 - Intermediate Dose, NVC-001 - High Dose - LMNA-Related Dilated Cardiomyopathy | Phase 1 / Phase 2 | Recruiting | Nuevocor Pte. Ltd. | 21 | 2026-06-16 | 2026-08-07 |
| Safety and Efficacy of Second Infusion of FAP iCDC in End-stage Dilated Cardiomyopathy FAP immunosuppressive CAR-DC - Dilated Cardiomyopathy (DCM), Heart Failure | Phase 1 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 5 | 2026-05-11 | 2026-07-02 |
| Effect of Sildenafil on Left Ventricular Function in Pediatric With Primary Dilated Cardiomyopathy Cardiomyopathy, Dilated | Not yet recruiting | Assiut University | 70 | 2026-05-10 | 2026-04-17 | |
| A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy RP-A701 is a recombinant viral vector composed of an AAV serotype rh.74 (AAVrh.74) capsid encapsulating the transgene, BCL2-associated Athanogene 3 (BAG3) - Dilated Cardiomyopathy (DCM) | Phase 1 | Recruiting | Rocket Pharmaceuticals Inc. | 8 | 2026-04-17 | 2026-10-01 |
| Mainstreaming Genetic Testing for Non-Ischemic Cardiomyopathy in Western Canada Health service delivery change - Nonischemic Cardiomyopathy, Dilated Cardiomyopathy (DCM) | Not applicable | Enrolling by invitation | Thomas Roston | 300 | 2026-02-02 | 2026-05-08 |
| Endocardial Delivery for Myocardial Regeneration Using Allogeneic iPSC-derived Cardiomyocyte Spheroids for HF With Systolic Dysfunction (EMERALD Study) HS-005 - Heart Failure, Ischemic Heart Failure | Phase 1 / Phase 2 | Recruiting | Heartseed Inc. | 14 | 2026-01-19 | 2026-10-22 |
| Prognostic Values of Coronary Microvascular Dysfunction in Patients With Dilated Cardiomyopathy coronary angiography - Dilated Cardiomyopathy (DCM) | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 330 | 2026-01-06 | 2025-12-19 | |
| A Study of AZD4063 in PLN R14del Dilated Cardiomyopathy AZD4063 - Dilated Cardiomyopathy | Phase 1 | Recruiting | AstraZeneca | 23 | 2025-12-01 | 2026-09-04 |
| the Clinical Outcome of Empagliflozin in Pediatric Heart Failure Patients Empagliflozin (EMPA), Standard medical treatment - Heart Failure | Phase 2 | Recruiting | Ain Shams University | 60 | 2025-12-01 | 2026-07-09 |
| Study of the Progression of Chronic Cardiovascular Conditions Cardiovascular Disease (CVD), Heart Failure | Recruiting | Prolaio | 5000 | 2025-10-30 | 2026-08-12 | |
| Multimodal Analysis of Endomyocardial Biopsies Heart Transplantation, Dilated Cardiomyopathy (DCM) | Recruiting | University Hospital, Essen | 216 | 2025-10-27 | 2026-01-22 | |
| MyocarditIRM-Génétique - Genetic Sub-study of the French Cohort of Acute Myocarditis Cases Diagnosed by MRI Acute Myocarditis | Active not recruiting | French Cardiology Society | 602 | 2025-07-15 | 2026-07-21 | |
| A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM) Allogeneic Neonatal mesenchymal stromal cells (nMSCs) - Dilated Cardiomyopathy | Phase 1 | Recruiting | Emory University | 36 | 2025-07-14 | 2026-06-26 |
| Protein A Immunoadsorption in Dilated Cardiomyopathy (RPIA-DCM) Immunoadsorption - Dilated Cardiomyopathy (DCM) | Not applicable | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 60 | 2025-06-04 | 2025-06-04 |
| National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry whole genome sequencing - Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated | Recruiting | Hospital do Coracao | 1211 | 2025-04-30 | 2026-05-08 | |
| Safety and Efficacy of FAP iCDC in End-stage Dilated Cardiomyopathy FAP immunosuppressive CAR-DC - Dilated Cardiomyopathy (DCM), Heart Failure | Phase 1 / Phase 2 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 43 | 2025-04-22 | 2026-07-14 |
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Heart Failure (91) · Cardiomyopathy, Hypertrophic (38) · Cardiomyopathies (35) · Cardiomyopathy, Restrictive (14) · Arrhythmogenic Right Ventricular Dysplasia (13) · Death, Sudden, Cardiac (13) · Heart Diseases (12) · Cardiovascular Diseases (11) · Myocarditis (9) · Arrhythmias, Cardiac (7) · Coronary Disease (7) · Myocardial Infarction (7) · Myocardial Ischemia (6) · Atrial Fibrillation (5)
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ARRY-371797 (3) · Adrenergic beta-Antagonists (3) · Cardiac Resynchronization Therapy (3) · Carvedilol (3) · Drug Therapy (3) · Granulocyte Colony-Stimulating Factor (3) · Standard of Care (3) · Allopurinol (2) · Blood Coagulation Tests (2) · Blood Specimen Collection (2) · Genetic Testing (2) · Hematologic Tests (2) · Ivabradine (2) · Metoprolol (2) · Plasmapheresis (2)
Imperial College London (9) · University Medical Centre Ljubljana (6) · LoneStar Heart, Inc. (4) · Ancora Heart, Inc. (3) · AstraZeneca (3) · French Cardiology Society (3) · Göteborg University (3) · Hospital General Universitario Gregorio Marañon (3) · Institut National de la Santé Et de la Recherche Médicale, France (3) · Johns Hopkins University (3) · McGill University Health Centre/Research Institute of the McGill University Health Centre (3) · Ministry of Health, Brazil (3) · National Heart, Lung, and Blood Institute (NHLBI) (3) · National Taiwan University Hospital (3) · Pfizer (3)
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