10 completed, 5 unknown, 3 terminated, 2 recruiting. 15 Not applicable, 3 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 15 | Completed 7, Terminated 3, Recruiting 2, Unknown 2, Withdrawn 1 |
| Phase 3 | 3 | Unknown 2, Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow Early Goal-Directed Therapy: new trials by email Literature Review of Early Goal-Directed Therapy trials Research Report on Early Goal-Directed Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of GDHT (Goal Directed Hemodynamic Therapy) Using a Non-invasive Hemodynamic Monitoring in Elective Neurosurgery Standard monitoring, Goal-Directed Therapy - Surgery Complications | Not applicable | Recruiting | Brno University Hospital | 140 | 2025-12-01 | 2026-10-15 |
| Non-invasive Goal-directed thErapy oN cIrcUlatory Shock Goal-Directed Therapy - Hemodynamics Instability | Not applicable | Recruiting | University of Sao Paulo | 380 | 2024-02-20 | 2024-08-26 |
| Goal-Directed Therapy Following Cardiac Surgery Goal-directed therapy - Surgery | Not applicable | Completed | University of Calgary | 100 | 2023-11-01 | 2026-05-14 |
| Cost-effectiveness of EGDT Using FloTrac/EV1000 Early goal-directed therapy (EGDT) - Coronary Artery Disease | Unknown | Khon Kaen University | 60 | 2023-04-01 | 2023-04-24 | |
| Goal-directed Therapy in Neurosurgery. Goal-Directed Therapy, STANDARD - Surgery--Complications | Not applicable | Completed | Brno University Hospital | 34 | 2021-03-01 | 2022-05-04 |
| Days Alive and Out of Hospital for Patients With Sepsis Hydroxyethyl starch, Hydrocortisone, Early Goal Directed Therapy - Sepsis, Septic Shock | Completed | The George Institute for Global Health, Australia | 6213 | 2020-09-14 | 2024-02-23 | |
| Taking Brain Monitoring to the Next Level Goal directed therapy (GDT) - Postoperative Cognitive Dysfunction, Postoperative Delirium | Not applicable | Completed | University of California, Los Angeles | 7 | 2020-01-30 | 2023-01-19 |
| Comparing the Prognosis of Lactate-directed and Goal-directed Therapy in Hyperthermic Intraperitoneal Chemotherapy. Lactate-directed therapy, Goal-directed therapy - Organ Failure, Multiple | Not applicable | Withdrawn | Taipei Medical University WanFang Hospital | 2019-05-06 | 2020-06-04 | |
| The Effect of Goal-directed Hemodynamic Therapy in Radical Cystectomy Goal-directed therapy - Bladder Cancer, Radical Cystectomy | Not applicable | Completed | Seoul National University Hospital | 82 | 2018-04-20 | 2022-09-23 |
| Controlled Fluid Resuscitation in Sepsis Early Goal Directed Therapy, Ruijin Strategy - Sepsis | Not applicable | Unknown | Ruijin Hospital | 550 | 2018-01-01 | 2017-07-12 |
| Goal Directed Therapy Versus Standard Care in Lung Resection Surgery (GDT-thorax Study). Standard care, Goal directed therapy - Goal Directed Therapy, Fluid Therapy | Not applicable | Completed | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 31 | 2017-10-10 | 2021-10-20 |
| Does Perioperative Goal Directed Therapy Using Flotrac Improve Outcomes in Esophagectomy Patients Goal Directed Therapy - Esophageal Cancer | Not applicable | Terminated | Medical University of South Carolina | 53 | 2016-06-01 | 2021-03-02 |
| Goal Directed Hemodynamic Management of Acute Heart Failure After Cardiac Surgery in Children Goal directed therapy, Control - Cardiac Surgery | Phase 3 | Unknown | Meshalkin Research Institute of Pathology of Circulation | 40 | 2015-12-01 | 2015-12-18 |
| Goal-directed Therapy in High-risk Surgery Protocol group 2, Protocol group 1 - Perioperative/Postoperative Complications, Hypovolemia | Not applicable | Unknown | Guangzhou First People's Hospital | 72 | 2012-09-01 | 2012-09-07 |
| Perioperative Fluid Management: Goal-directed Versus Restrictive Strategy Goal-directed therapy, Restrictive fluid therapy - Complication, Postoperative | Phase 3 | Completed | University Hospital, Geneva | 400 | 2012-01-01 | 2019-09-12 |
| GDT Vs ST for Pancreas Transplant Surgery Goal-Directed Therapy, Standard Therapy - Pancreas Transplantation | Not applicable | Completed | University of Manchester | 60 | 2011-11-01 | 2015-12-03 |
| Arterial Pulse Waveform Contour Analysis for Intraoperative Goal Directed Therapy in Major Spine Surgery goal directed therapy - Surgical Procedures, Operative | Not applicable | Terminated | Loma Linda University | 5 | 2010-12-01 | 2012-04-12 |
| Goal Directed Therapy for Acute Kidney Injury in Critical Ill Patients Goal-directed therapy - Acute Kidney Injury | Phase 2 | Completed | Barretos Cancer Hospital | 99 | 2010-06-01 | 2015-04-13 |
| Impact of Early Goal-directed Fluid Therapy in Hypovolemic Patients Undergoing Emergency Surgery CONTROL, OPTIMIZED - Hypovolemic Shock, Trauma | Not applicable | Terminated | University Hospital, Geneva | 20 | 2010-02-01 | 2016-05-13 |
| Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial Early Goal Directed Therapy (EGDT) - Severe Sepsis | Phase 3 | Unknown | Belinda Howe | 1600 | 2008-10-01 | 2014-04-24 |
Showing 20 of 21. Sign in to see all of them.
Sepsis (5) · Postoperative Complications (3) · Shock, Septic (3) · Acute Kidney Injury (2) · Shock (2) · Acute Lung Injury (1) · Arrhythmias, Cardiac (1) · Body Weight (1) · Coronary Artery Disease (1) · Emergence Delirium (1) · Emergencies (1) · Esophageal Neoplasms (1) · Heart Defects, Congenital (1) · Heart Failure (1) · Hypovolemia (1)
Brno University Hospital (2) · University Hospital, Geneva (2) · Barretos Cancer Hospital (1) · Belinda Howe (1) · Fundación Pública Andaluza para la gestión de la Investigación en Sevilla (1) · Guangzhou First People's Hospital (1) · Khon Kaen University (1) · Loma Linda University (1) · Medical University of South Carolina (1) · Meshalkin Research Institute of Pathology of Circulation (1) · Ruijin Hospital (1) · Seoul National University Hospital (1) · Taipei Medical University WanFang Hospital (1) · The George Institute for Global Health, Australia (1) · University of Calgary (1)
United States (4) · Australia (2) · Czechia (2) · Switzerland (2) · Brazil (1) · Canada (1) · China (1) · Finland (1) · Hong Kong (1) · Ireland (1) · New Zealand (1) · Russia (1) · South Korea (1) · Spain (1) · Thailand (1)
Derek C. Angus, MD, MPH (1) · Donald M. Yealy, MD (1) · George Guldan, MD (1) · Gordana Pavlovic, MD (1) · Hussein A Khambalia, BMBS (1) · John A. Kellum, MD (1) · Ludhmila A Hajjar, MD, PhD (1) · Manuel Bertomeu, MD-PhD (1) · Marc Licker, MD (1) · Rajesh Kumar, PhD (1) · Richard L Applegate, M.D. (1) · Rinaldo Bellomo (1) · Roman Gal, M.D., Ph.D. (1) · Sandra L Peake (1) · Sirirat Tribuddharat, MD, PhD (1)
PMID 1594234, PMID 23447502, PMID 24086168, PMID 24099368, PMID 24635773, PMID 25272316, PMID 25986476, PMID 28109962, PMID 29369117, PMID 30379222, PMID 30458880, PMID 30985391, PMID 32584598, PMID 34234581, PMID 35989328, PMID 37408018, PMID 37814224, PMID 38046082