10 completed, 5 terminated, 5 unknown, 2 recruiting. 22 Phase 3, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 22 | Completed 10, Terminated 5, Unknown 5, Recruiting 2 |
| Phase 2 | 7 | Completed 4, Unknown 3 |
Follow Cardiomyopathy, Dilated: new trials by email Literature Review of Cardiomyopathy, Dilated trials Research Report on Cardiomyopathy, Dilated
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive Age Bromocriptine mesylate plus standard GDMT - Dilated Cardiomyopathy | Phase 3 | Recruiting | Jimma University | 112 | 2024-10-21 | 2024-11-19 |
| Effect of Dapagliflozin on Cardiac Structure, Function and Secondary Mitral Regurgitation in Patients with Left Ventricle Dysfunction Dapagliflozin Farxiga®, Ramipril Tritace®, Carvedilol Carvid®,and Spironolactone Aldactone® - Dilated Cardiomyopathy | Phase 3 | Completed | October 6 University | 150 | 2023-04-27 | 2024-10-16 |
| Early Treatment With Candesartan vs Placebo in Genetic Carriers of Dilated Cardiomyopathy (EARLY-GENE Trial) Candesartan - Cardiomyopathy, Dilated | Phase 3 | Recruiting | Cristina Avendaño Solá | 320 | 2022-06-02 | 2024-11-07 |
| Micophenolate Mofetil Versus Azathioprine in Myocarditis mycophenolate mofetil 2 g per day, azathioprine of 150 [75; 150] mg per day - Lymphocytic Myocarditis (Disorder), Heart Failure | Phase 3 | Completed | I.M. Sechenov First Moscow State Medical University | 50 | 2020-10-01 | 2025-07-15 |
| Bisoprolol in DMD Early Cardiomyopathy Bisoprolol Fumarate - Duchenne Muscular Dystrophy, Cardiomyopathy, Dilated | Phase 2 / Phase 3 | Unknown | Peking Union Medical College Hospital | 42 | 2019-01-16 | 2022-09-28 |
| Resveratrol: A Potential Anti- Remodeling Agent in Heart Failure, From Bench to Bedside Resveratrol, Placebo - Dilated Cardiomyopathy | Phase 3 | Unknown | St. Boniface Hospital | 40 | 2018-10-09 | 2018-11-14 |
| A Study of ARRY-371797 (PF-07265803) in Patients With Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation ARRY-371797 (PF-07265803), Placebo - Dilated Cardiomyopathy, Lamin A/C Gene Mutation | Phase 3 | Terminated | Pfizer | 77 | 2018-04-17 | 2024-01-09 |
| Follow-up Safety Trial in Children With Chronic Heart Failure Therapy Receiving Orodispersible Minitablets of Enalapril Enalapril Orodispersible Minitablet - Heart Failure, Dilated Cardiomyopathy | Phase 2 / Phase 3 | Unknown | Ethicare GmbH | 100 | 2016-03-01 | 2016-01-13 |
| Orodispersible Minitablets of Enalapril in Children With Heart Failure Due to Dilated Cardiomyopathy Enalapril Orodispersible Minitablet - Heart Failure, Dilated Cardiomyopathy | Phase 2 / Phase 3 | Unknown | Ethicare GmbH | 50 | 2016-01-01 | 2016-01-12 |
| Honey in Idiopathic Dilated Cardiomyopathy honey - Idiopathic Dilated Cardiomyopathy | Phase 2 / Phase 3 | Completed | mamdouh abdulmaksoud abdulrhman | 50 | 2015-11-01 | 2016-12-12 |
| Continues Positive Airway Pressure Treatment for Patients With Dilated Cardiomyopathy and Obstructive Sleep Apnea Continues Positive Airway Pressure (CPAP) - Dilated Cardiomyopathy, Obstructive Sleep Apnea | Phase 3 | Unknown | Göteborg University | 44 | 2014-11-01 | 2018-03-08 |
| Repetitive Intramyocardial CD34+ Cell Therapy in Dilated Cardiomyopathy (REMEDIUM) Stem cell therapy - Dilated Cardiomyopathy, Heart Failure | Phase 2 / Phase 3 | Completed | University Medical Centre Ljubljana | 66 | 2014-01-01 | 2018-01-23 |
| A Randomized, Controlled Study to Evaluate Algisyl-LVR™ as a Method of Left Ventricular Augmentation for Heart Failure Algisyl-LVR, Standard medical therapy - Heart Failure, Dilated Cardiomyopathy | Phase 2 / Phase 3 | Completed | LoneStar Heart, Inc. | 78 | 2012-08-01 | 2017-03-15 |
| PREclinical Mutation CARriers From Families With DIlated Cardiomyopathy and ACE Inhibitors perindopril, placebo - Dilated Cardiomyopathy | Phase 3 | Terminated | Institut National de la Santé Et de la Recherche Médicale, France | 6 | 2011-12-01 | 2016-02-24 |
| Mental Stress Reduction in Defibrillator Patients Cognitive Behavioral Stress Management (CBSM), Patient Education - Cardiomyopathy, Dilated, Arrhythmia | Phase 3 | Terminated | US Department of Veterans Affairs | 129 | 2008-09-01 | 2014-12-22 |
| The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow Distribution Enalaprilat - Hypertension, Congestive Cardiomyopathy | Phase 3 | Completed | The Hospital for Sick Children | 12 | 2008-07-01 | 2015-12-18 |
| Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure Surgical mitral valvuloplasty with placement of annular ring (SMVR), Optimal medical therapy (OMT) - Mitral Valve Insufficiency, Heart Failure | Phase 3 | Terminated | Duke University | 2 | 2008-03-01 | 2018-04-04 |
| PUFAs and Left Ventricular Function in Heart Failure n-3 PUFAs, Placebo - Dilated Cardiomyopathy, Heart Failure | Phase 3 | Completed | Università degli Studi di Brescia | 133 | 2007-11-01 | 2012-01-31 |
| Effect of Rosuvastatin on Left Ventricular Remodeling Rosuvastatin, placebo - Dilated Cardiomyopathy | Phase 3 | Completed | Oslo University Hospital | 75 | 2007-07-01 | 2014-01-27 |
| Cell Therapy In Dilated Cardiomyopathy optimal therapy for cardiaca failure, cell - Dilated Cardiomyopathy | Phase 3 | Completed | Ministry of Health, Brazil | 115 | 2006-01-01 | 2017-03-13 |
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Heart Failure (11) · Cardiomyopathies (4) · Death, Sudden, Cardiac (2) · Arrhythmias, Cardiac (1) · Chagas Cardiomyopathy (1) · Heart Defects, Congenital (1) · Hypertension (1) · Inflammation (1) · Limb-girdle muscular dystrophy, type 1B (1) · Mitral Valve Insufficiency (1) · Muscular Dystrophy, Duchenne (1) · Myocarditis (1) · Sleep Apnea, Obstructive (1) · Stress, Psychological (1)
Cardiomegaly (22) · Cardiovascular Diseases (22) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (22) · Genetic Diseases, Inborn (22) · Heart Diseases (22) · Laminopathies (22) · Cardiomyopathies (18) · Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Death (2) · Death, Sudden (2) · Heart Arrest (2) · Nervous System Diseases (2) · Apnea (1) · Behavior (1)
ARRY-371797 (1) · Bisoprolol (1) · Bromocriptine (1) · Carboxylesterase (1) · Drug Therapy (1) · Enalaprilat (1) · Granulocyte Colony-Stimulating Factor (1) · Honey (1) · Mycophenolic Acid (1) · Omacor (1) · Patient Education as Topic (1) · Perindopril (1) · Ramipril (1) · Resveratrol (1) · Rosuvastatin Calcium (1)
Ethicare GmbH (2) · Ministry of Health, Brazil (2) · Cristina Avendaño Solá (1) · Duke University (1) · Göteborg University (1) · I.M. Sechenov First Moscow State Medical University (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Instituto de Cardiologia do Rio Grande do Sul (1) · Jimma University (1) · LoneStar Heart, Inc. (1) · October 6 University (1) · Oslo University Hospital (1) · Peking Union Medical College Hospital (1) · Pfizer (1) · St. Boniface Hospital (1)
Netherlands (5) · Canada (4) · Italy (4) · United Kingdom (4) · Brazil (3) · Spain (3) · United States (3) · Austria (2) · Germany (2) · Hungary (2) · Norway (2) · Serbia (2) · Argentina (1) · Australia (1) · Belgium (1)
Ida Jovanovic, Prof,MD,PhD (2) · Michael Burch, Prof,MD,PhD (2) · Ahmed Essam Abou Warda (1) · Augusto Z Bozza, MD (1) · Bernardo R Tura, Md,MsC (1) · Christoph Male, Prof, MD,PhD (1) · Christoph Male, Prof,MD,PhD (1) · Douglas Russell, MD PhD (1) · Estner F Heidi, MD, cardiologist (1) · Eugene Braunwald, MD (1) · Geir Gokstad (1) · Gilson Feitosa, MD (1) · Haas A Nikolaus, MD, Cardiologist (1)
PMID 10368877, PMID 11710893, PMID 12457625, PMID 17289576, PMID 18455424, PMID 19146917, PMID 19445426, PMID 20308616, PMID 22523306, PMID 22596155, PMID 23619365, PMID 24586994, PMID 24847587, PMID 26010524, PMID 26082085, PMID 26392433, PMID 26555602, PMID 26792875, PMID 27339497, PMID 28636901, PMID 29260409, PMID 29380563, PMID 29880546, PMID 31132311, PMID 31488387, PMID 31974027, PMID 32277062, PMID 32298005, PMID 33461482, PMID 34725781, PMID 36261102, PMID 36718638, PMID 37010012, PMID 37788487, PMID 38979608, PMID 39145700, PMID 41693767, PMID 557719
2015 (2), 2017 (1), U01HL084904 (1)