110 completed, 17 unknown, 10 terminated, 7 recruiting. 75 Not applicable, 36 Phase 2, 25 Phase 1, 12 Phase 3, 6 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| RESvEraTrol in Parkinson's Disease (RESET) Trans-Resveratrol - Parkinson's Disease | Phase 2 | Recruiting | Georgetown University | 30 | 2026-09-17 | 2026-09-18 |
| Serum Endogenous Estrogens, Estrogen Receptors, and Sirtuin-1 and -3 After Resveratrol Supplementation Trans-resveratrol, 1000 mg daily for 90 days, Placebo - Coronary Artery Disease (CAD), Menopause | Not applicable | Recruiting | InCor Heart Institute | 80 | 2026-08-24 | 2026-10-16 |
| Resveratrol for Endothelial Dysfunction and Metabolic Control in Type 2 Diabetes Resveratrol, Placebo - Type 2 Diabetes Mellitus, Endothelial Dysfunction | Not applicable | Completed | Universitas Sriwijaya | 48 | 2026-05-01 | 2026-06-16 |
| Evaluation of the Hepatoprotective Effects of a Nutritional Supplement in Patients With Liver Disease Secondary to Chronic Hepatitis C Virus Infection (RESQUETI Study). resveratrol, quercetin, taurine, whey protein, and inulin, whey protein - Liver Disease Chronic, HEPATITIS C VIRUS CHRONIC INFECTION | Not applicable | Recruiting | University of Guadalajara | 26 | 2025-10-11 | 2026-03-23 |
| Comparative Efficacy of Resveratrol 1 % Gel and Trichloroacetic Acid 20% in Treatment of Melasma: A Split-face Study resveratrol 1 % gel, TCA20% - Melasma | Not applicable | Not yet recruiting | Assiut University | 41 | 2025-07-22 | 2025-07-11 |
| Strength Training and Resveratrol Resistance training, Resveratrol 500 mg oral once daily., Placebo - Sarcopenia, Anabolic Resistance | Not applicable | Recruiting | Texas Tech University | 36 | 2025-06-13 | 2026-07-07 |
| Comparative Evaluation of Omega-3 and Resveratrol Supplementation in Periodontitis Patients trans-resveratrol, Omega-3 (EPA+DHA), No supplementation - Periodontitis | Active not recruiting | Izmir Katip Celebi University | 60 | 2025-01-01 | 2026-09-18 | |
| Effect of Resveratrol Supplementation on Exercise Performance and Recovery Resveratrol (VRES) 500 mg oral once daily., Placebo 500 mg oral once daily. - Effect of Resveratrol on Performance and Recovery | Not applicable | Recruiting | University of Central Florida | 20 | 2024-10-01 | 2024-12-09 |
| Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus Clobetasol Patch, Clobetasol + Resveratrol Patch, Clobetasol in Orabase - Oral Lichen Planus, Oral Lichen Planus Related Stress | Phase 2 | Recruiting | University of Palermo | 45 | 2024-09-04 | 2025-08-03 |
| Effects of Resveratrol Supplementation on Oocyte Quality Resveratrol, Folic acid - Aging, Infertility | Not applicable | Unknown | Unidade Local de Saúde de Coimbra, EPE | 88 | 2024-09-01 | 2024-01-31 |
| RQC for the Prevention of Alzheimer's Disease and Retinal Amyloid-β Resveratrol, Quercetin, and Curcumin (RQC), Curcumin - Alzheimer Disease, Mild Cognitive Impairment | Phase 2 | Not yet recruiting | Zaparackas and Knepper LTD | 200 | 2024-07-01 | 2024-06-26 |
| Resveratrol for the Prevention of Bone Loss in Postmenopausal Women Resveratrol, Placebo - Low Bone Mass | Not applicable | Completed | University of Delaware | 52 | 2024-02-02 | 2026-05-13 |
| Study of High-Dose Resveratrol in Patients With Stable Ischemic Heart Disease High-dose resveratrol 500 mg/day, Placebo - Ischaemic Heart Desease | Not applicable | Completed | S.LAB (SOLOWAYS) | 70 | 2024-02-01 | 2025-04-23 |
| Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWI Curcumin, Resveratrol, Stinging Nettle - Gulf War Illness | Not applicable | Completed | University of Alabama at Birmingham | 390 | 2023-05-31 | 2026-06-29 |
| The Effects of Resveratrol on Sirtuins and Apoptosis Biomarkers Resveratrol, Placebo - Coronary Artery Disease, Menopause | Not applicable | Unknown | InCor Heart Institute | 80 | 2023-03-06 | 2023-04-11 |
| Assessment of Antioxidant Therapy on Oxidative Stress Biomarkers in Type 2 Diabetic Patients With Neuropathy Resveratrol, Alpha lipoic acid, Super oxide dismutase, Resveratrol, Alpha lipoic acid - Peripheral Diabetic Neuropathy | Phase 2 | Completed | Khyber Medical University Peshawar | 100 | 2023-01-09 | 2024-08-26 |
| Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS Resveratrol, Metformin, Acetyl-L-Carnitin, L Arginine, Co-Q10 - PCOS | Not applicable | Completed | Khyber Medical University Peshawar | 120 | 2022-12-07 | 2024-02-23 |
| Anti-age Dietary Supplements in Healthy Older Adults: the proBNPage Reduction Trial Coenzyme Q10, Selenium, Resveratrol - Aging | Not applicable | Unknown | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 120 | 2022-07-22 | 2023-02-02 |
| Biological Effects in Consumers of Resveratrol-enriched Wine Wine enriched with Resveratrol - Aging, Healthy Aging | Completed | PINER Pastor Manfredi Winery | 30 | 2022-07-15 | 2023-08-08 | |
| VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements Study Drugs and Nutritional Supplements - Aging | Phase 1 | Withdrawn | Vitality in Aging Research Group, Inc. | 2022-06-01 | 2022-06-07 |
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Insulin Resistance (18) · Diabetes Mellitus, Type 2 (12) · Obesity (12) · Diabetes Mellitus (11) · Inflammation (9) · Metabolic Syndrome (9) · Glucose Intolerance (6) · Coronary Artery Disease (5) · Non-alcoholic Fatty Liver Disease (5) · Parkinson Disease (5) · Alzheimer Disease (4) · Cognitive Dysfunction (4) · COVID-19 (3) · Glucose Metabolism Disorders (3) · Hypertension (3)
Northumbria University (9) · Maastricht University Medical Center (7) · University of Aarhus (5) · Bial - Portela C S.A. (4) · National Cancer Institute (NCI) (4) · Augusta University (3) · InCor Heart Institute (3) · Khyber Medical University Peshawar (3) · University of Florida (3) · University of Guadalajara (3) · Albert Einstein College of Medicine (2) · Assistance Publique - Hôpitaux de Paris (2) · Boston University (2) · IVI Madrid (2) · Murdoch Childrens Research Institute (2)
United States (58) · United Kingdom (10) · Italy (9) · Canada (8) · Brazil (7) · Denmark (7) · Netherlands (7) · Mexico (5) · France (4) · Germany (3) · Pakistan (3) · Portugal (3) · Australia (2) · China (2) · Iran (2)
Mary M McDermott, MD (2) · Paul A Knepper, MD, PhD (2) · Paula Rodriguez Miguelez, PhD (2) · Simona Bo, MD (2) · Ajoy C Karikkineth, M.D. (1) · Annemie Schols, Prof. (1) · Antonio P Mansur, PhD (1) · Antonio de Padua Mansur, PhD Incor (1) · Araceli Montoya-Estrada, PhD (1) · Arash Hosseinnejad, MD-PhD (1)
PMID 25311610, PMID 37843843, PMID 37916745, PMID 10963727, PMID 11556815, PMID 12523673, PMID 15333514, PMID 16626303, PMID 17069794, PMID 17086191, PMID 17112576, PMID 17578889, PMID 18266981, PMID 19100718, PMID 19638084, PMID 19819963, PMID 20428452, PMID 20463039, PMID 20935227, PMID 21188121, PMID 21261640, PMID 21385509, PMID 21569266, PMID 21673955, PMID 21688389, PMID 22219517, PMID 22419935, PMID 22913271, PMID 23091400, PMID 23174266, PMID 23193181, PMID 23205612, PMID 23528916, PMID 23663119, PMID 24072699, PMID 24604232, PMID 24804871, PMID 24827888, PMID 24866496, PMID 25050904, PMID 25051174, PMID 25115686, PMID 25322274, PMID 25332827, PMID 25577300, PMID 25790328, PMID 26621580, PMID 26829441, PMID 26840331, PMID 27194304
N01CN35158 (2), P30CA023074 (2), P30CA046592 (2), 2009 (1), P01HL068758 (1), R01AT007564 (1), R01HL137087 (1), R21AG047510 (1), R21AG049974 (1), R21CA149560 (1), R34HL138235 (1), R44AG067907 (1), R56HL114073 (1), U19AT010835 (1), U54GM104941 (1)