5 completed, 4 recruiting, 1 active not recruiting, 1 not yet recruiting. 15 Phase 2, 4 Phase 1.
Follow Cannabis Use: new trials by email Literature Review of Cannabis Use trials Research Report on Cannabis Use
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Cannabidiol on Psychiatric Symptoms, Cognition, and Cannabis Consumption in Cannabis Users With Recent-Onset Psychosis Cannabidiol (CBD), Placebo - Schizophrenia Spectrum Disorders, Cannabis Use | Phase 2 | Withdrawn | University of Maryland, Baltimore | 2050-01-01 | 2021-04-19 | |
| Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery Cannabidiol (CBD) only, Placebo only, Delta-9-tetrahydrocannabinol (THC) only - PTSD, Post Traumatic Stress Disorder | Phase 1 / Phase 2 | Not yet recruiting | Leslie Lundahl | 280 | 2026-09-01 | 2026-08-26 |
| Warrior CARE: Cannabis Behavioral Health Tetrahydrocannabinol, Cannabidiol, Placebo - Post Traumatic Stress Disorder, Cannabis Use | Phase 1 / Phase 2 | Recruiting | Wayne State University | 500 | 2025-09-22 | 2026-08-07 |
| Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration Cannabis, Nicotine, Pax Loose Leaf Vaporizer - THC, Cannabis | Phase 2 | Recruiting | University of California, San Francisco | 48 | 2025-07-01 | 2026-01-07 |
| Acute Effects of Cannabis on Everyday Life Memory Cannabis, Placebo - Cannabis Use | Phase 2 | Completed | Washington State University | 121 | 2023-08-21 | 2025-11-24 |
| Cannabis' Impact on Alcohol Consumption THC-dominant cannabis, CBD-dominant cannabis, Cannabis placebo - Alcohol Drinking, Cannabis Use | Phase 2 | Recruiting | Brown University | 350 | 2023-03-16 | 2026-10-05 |
| SV2A in Older Adults [11C]UCB-J PET - Cannabis Use | Phase 1 / Phase 2 | Recruiting | Yale University | 24 | 2022-07-06 | 2026-10-20 |
| A Trial of Guanfacine-er for Cannabis Use Disorder guanfacine-ER, Placebo - Cannabis Use | Phase 2 | Completed | New York State Psychiatric Institute | 22 | 2022-06-01 | 2026-08-18 |
| Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders Gabapentin, Placebo - Bipolar Disorder, Cannabis Use | Phase 2 | Completed | Medical University of South Carolina | 51 | 2022-02-24 | 2026-09-09 |
| Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity THC Cannabis, CBD Cannabis, Placebo - HIV, Cannabis Use | Phase 2 | Active not recruiting | University of California, San Diego | 40 | 2021-02-19 | 2025-10-15 |
| Safety and Efficacy of Inhaled Cannabis For the Uncontrolled Pain Relief in Patients With Advanced Cancer PPP001, Placebo - Cancer Pain, Quality of Life | Phase 2 | Unknown | Tetra Bio-Pharma | 78 | 2020-07-30 | 2021-09-16 |
| Influence of Tobacco Use on Cannabis Use 7 days of Tobacco Cessation, 21 days of Tobacco Cessation, Cannabis - Cannabis Use, Tobacco Use | Phase 2 | Suspended | New York State Psychiatric Institute | 160 | 2020-02-01 | 2026-09-01 |
| Eye Tracking as a Biomarker of Cannabis Effects Cannabis - Cannabis Use, Pain, Acute | Phase 2 | Terminated | New York State Psychiatric Institute | 1 | 2019-10-01 | 2022-06-30 |
| Impact of Progesterone on Stress Reactivity and Cannabis Use Progesterone, Placebo - Cannabis Use | Phase 2 | Completed | Medical University of South Carolina | 148 | 2019-01-18 | 2023-09-28 |
| Effect of Lorcaserin on Cannabis Withdrawal and Self-administration Lorcaserin, Placebo, Marijuana - Cannabis Use | Phase 1 / Phase 2 | Completed | New York State Psychiatric Institute | 15 | 2017-09-05 | 2022-07-26 |
Marijuana Abuse (5) · Acute Pain (2) · Psychotic Disorders (2) · Stress Disorders, Post-Traumatic (2) · Suicide (2) · Tobacco Use (2) · Alcohol Drinking (1) · Alcoholism (1) · Behavior, Addictive (1) · Bipolar Disorder (1) · Cancer Pain (1) · Lymphoma, Follicular (1) · Marijuana Smoking (1) · Schizophrenia (1) · Vaping (1)
Mental Disorders (7) · Behavior (5) · Chemically-Induced Disorders (5) · Substance-Related Disorders (5) · Behavioral Symptoms (2) · Neurologic Manifestations (2) · Pain (2) · Pathological Conditions, Signs and Symptoms (2) · Schizophrenia Spectrum and Other Psychotic Disorders (2) · Self-Injurious Behavior (2) · Signs and Symptoms (2) · Stress Disorders, Traumatic (2) · Trauma and Stressor Related Disorders (2) · Alcohol-Related Disorders (1) · Bipolar and Related Disorders (1)
nabiximols (7) · Cannabidiol (3) · Dronabinol (3) · Ethanol (1) · Gabapentin (1) · Nicotine (1) · Progesterone (1) · Single Person (1) · lorcaserin (1)
New York State Psychiatric Institute (4) · Medical University of South Carolina (2) · Brown University (1) · Leslie Lundahl (1) · Tetra Bio-Pharma (1) · University of California, San Diego (1) · University of California, San Francisco (1) · University of Maryland, Baltimore (1) · Washington State University (1) · Wayne State University (1) · Yale University (1)
United States (15)
Carrie Cuttler (1) · Christina Brezing, MD (1) · Deepak C D'Souza, MBBS, MD (1) · Gideon St Helen (1) · James J Prisciandaro, PhD (1) · Jane Metrik, PhD (1) · Ryan McLaughlin, PhD (1) · Scott Letendre, MD (1)
K23DA045080 (1), R01AA029711 (1), R01DA054275 (1), R01DA056451 (1), U54DA016511 (1)