65 completed, 37 recruiting, 17 not yet recruiting, 13 unknown. 75 Not applicable, 20 Phase 1, 15 Phase 2, 6 Early Phase 1, 6 Phase 4.
Follow Cannabis Use: new trials by email Literature Review of Cannabis Use trials Research Report on Cannabis Use
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Cannabidiol on Psychiatric Symptoms, Cognition, and Cannabis Consumption in Cannabis Users With Recent-Onset Psychosis Cannabidiol (CBD), Placebo - Schizophrenia Spectrum Disorders, Cannabis Use | Phase 2 | Withdrawn | University of Maryland, Baltimore | 2050-01-01 | 2021-04-19 | |
| Behavioral Pharmacology of THC and Beta-Myrcene Placebo, THC, Beta-Myrcene - Cannabis Use | Phase 1 | Not yet recruiting | Johns Hopkins University | 32 | 2027-07-01 | 2026-07-31 |
| Transcranial Magnetic Stimulation for Adolescents and Young Adults With Cannabis Use Disorder Magstim SuperRapid2, Sham rTMS - Cannabis Use, Cannabis Use Disorder | Not applicable | Not yet recruiting | University of Minnesota | 50 | 2027-03-01 | 2026-06-09 |
| Activity-Based Intervention to Address Cannabis Use Motivational and Behavioral Economics Informed Intervention, Enhanced Usual Care - Cannabis Use | Not applicable | Not yet recruiting | University of Michigan | 300 | 2027-02-01 | 2026-09-14 |
| Research Investigating Drug Effects-2 (RiDE-2) Placebo Oral Capsule, THC - Cannabis Use, Substance Use Disorder (SUD) | Early Phase 1 | Not yet recruiting | University of Illinois at Chicago | 144 | 2027-01-04 | 2026-10-22 |
| Clinician Practice Companion to Address Youth Substance Use Practice Companion - Substance Use, Substance-Related Disorders | Not applicable | Not yet recruiting | Massachusetts General Hospital | 60 | 2027-01-01 | 2026-10-07 |
| Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance Cannabis - Cannabis Use, Impaired Driving | Phase 1 | Not yet recruiting | Johns Hopkins University | 40 | 2026-12-01 | 2026-10-16 |
| Cannabis and Opioid Use Disorder, Study 2 Inhaled Cannabis, Intranasal Opioid - Opioid Use Disorders, Cannabis Use | Phase 1 | Not yet recruiting | University of Kentucky | 100 | 2026-11-30 | 2026-10-09 |
| Cannabis Effects on Opioid Self-Administration Cannabis, Placebo Cannabis, Intranasal Opioid Agonist - Opioid Use Disorder, Cannabis Use | Phase 1 | Not yet recruiting | Shanna Babalonis, PhD | 30 | 2026-11-30 | 2026-10-14 |
| Lung Health and Breath Biomarkers: Acute Effects of Inhaled Cannabis Cannabis (THC), Tobacco Cigarette - Cannabis Use, Tobacco | Early Phase 1 | Not yet recruiting | Hannah Harris | 12 | 2026-11-01 | 2026-10-06 |
| Developing and Testing an Online Intervention for Alcohol and Cannabis Misuse and Healthy Relationship Skills Among Young Adult Couples Online, couples-based intervention - Alcohol Drinking, Cannabis Use | Not applicable | Not yet recruiting | University of Washington | 60 | 2026-10-01 | 2026-07-08 |
| vEAET-H for Chronic Pain Patients Using Medical Cannabis in Israel - A Feasibility Study Group-based virtual Emotional Awareness & Expression Therapy - Hebrew (vEAET-H) - Chronic Musculoskeletal Pain, Cannabis Use | Not applicable | Recruiting | Reuth Rehabilitation Hospital | 42 | 2026-10-01 | 2026-07-28 |
| Acute Effects of Cannabis on Cognition and Affect THC 20mg, Placebo - Cannabis Use | Phase 1 | Recruiting | Washington State University | 92 | 2026-09-11 | 2026-10-29 |
| Smart Talk: Cannabis Awareness and Prevention Curriculum Evaluation Behavioral: Smart Talk Cannabis Awareness and Prevention - Cannabis Use | Not applicable | Not yet recruiting | Stanford University | 10800 | 2026-09-01 | 2026-06-08 |
| Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery Cannabidiol (CBD) only, Placebo only, Delta-9-tetrahydrocannabinol (THC) only - PTSD, Post Traumatic Stress Disorder | Phase 1 / Phase 2 | Not yet recruiting | Leslie Lundahl | 280 | 2026-09-01 | 2026-08-26 |
| Brief Family-Based Cannabis Use Intervention for Youth With Early Juvenile Justice Involvement Brief Family Based Intervention, Parenting Psychoeducation - Cannabis Use, Delinquency | Not applicable | Not yet recruiting | Rhode Island Hospital | 60 | 2026-07-15 | 2026-07-14 |
| Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum Perinatal smoking cessation treatment and maintenance sessions - Perinatal, Cannabis Use | Not applicable | Recruiting | University of Pittsburgh | 25 | 2026-06-17 | 2026-07-06 |
| Neuroimaging of Adolescent Cannabis Use Treatment Contingency Management, Elastic Net Regression - Cannabis Use, Cannabis Dependence | Not applicable | Recruiting | Indiana University | 80 | 2026-06-15 | 2026-06-22 |
| Perceptions of Proposed Warnings for Cannabis Edibles Packaging No Warning Control, Delayed Effects Text Only, Delayed Effects Plus Icon - Cannabis Use | Not applicable | Completed | Wake Forest University Health Sciences | 1250 | 2026-05-27 | 2026-10-13 |
| Testing Warning Labels for Retail Cannabis Products Using a Discrete Choice Experiment Discrete choice experiment (DCE) survey-experiment - Cannabis Use, Risk Perception | Not applicable | Recruiting | University of Oklahoma | 450 | 2026-05-19 | 2026-07-27 |
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Marijuana Abuse (59) · Substance-Related Disorders (12) · Alcohol Drinking (11) · Psychotic Disorders (8) · Schizophrenia (7) · Tobacco Use (7) · Marijuana Use (6) · Adolescent Behavior (5) · Behavior, Addictive (5) · Marijuana Smoking (5) · Alcoholism (4) · Cognitive Dysfunction (4) · Depression (4) · Mental Disorders (4) · Opioid-Related Disorders (4)
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University of Michigan (7) · University of Washington (6) · Johns Hopkins University (5) · Medical University of South Carolina (5) · University of Colorado, Denver (5) · Centre hospitalier de l'Université de Montréal (CHUM) (4) · Duke University (4) · Massachusetts General Hospital (4) · National Institute on Drug Abuse (NIDA) (4) · New York State Psychiatric Institute (4) · University of Colorado, Boulder (4) · Yale University (4) · Centre for Addiction and Mental Health (3) · Wake Forest University Health Sciences (3) · Central Hospital, Nancy, France (2)
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Beth Reboussin, PhD (3) · Randi M Schuster, PhD (3) · Dustin Lee, PhD (2) · Erin Bonar (2) · Marilyn Huestis, Ph.D. (2) · Shanna Babalonis, PhD (2) · Aimee Aimee McRae-Clark, PharmD (1) · Alan Budney, PHD (1) · Alecia Dager, PhD (1) · Alina I Palimaru, PhD (1) · Amy C Justice, MD, PhD (1) · Ana Gleisner (1) · Andreana Benitez, PhD (1) · Antoinette Burger, PhD (1) · Antoni Gual, MD,PhD (1)
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