198 completed, 49 unknown, 30 recruiting, 16 terminated. 175 Not applicable, 39 Phase 2, 20 Phase 1, 17 Phase 4, 15 Phase 3.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Understanding Non-invasive Vagus Nerve Stimulation Effects in PTSD transcutaneous auricular vagus nerve stimulation, sham transcutaneous auricular vagus nerve stimulation - PTSD - Post Traumatic Stress Disorder | Early Phase 1 | Not yet recruiting | Wayne State University | 60 | 2027-04-01 | 2026-07-13 |
| Can Mindfulness and Virtual Reality Reduce Stress in Young Adults With Type 1 Diabetes? Mindfulness-Based Stress Reduction - Virtual Reality, Stress tip sheet - Type 1 Diabetes | Not applicable | Not yet recruiting | Wayne State University | 48 | 2026-10-31 | 2026-10-16 |
| Exercise and Nutrition Education for Older Adults With Spinal Cord Injury: A Pilot Randomized Controlled Trial Individualized Exercise Training, Nutrition Education, Behavioral Support - Spinal Cord Injuries, Aging | Phase 1 | Not yet recruiting | Wayne State University | 24 | 2026-10-19 | 2026-09-29 |
| Effects of Pharmacological Stress and rTMS on Executive Function in Opioid Use Disorder Yohimbine + Hydrocortisone, Active rTMS, Placebo - Opioid Use Disorder | Phase 2 | Not yet recruiting | Wayne State University | 20 | 2026-10-01 | 2025-12-30 |
| Positron Emission Tomography/Computed Tomography (PET/CT) Imaging in Patients Diagnosed With a Glioma Minocycline 200mg/day, [18F]FETrp PET/CT - Low Grade Glioma, Glioblastoma | Phase 2 | Not yet recruiting | Barbara Ann Karmanos Cancer Institute | 61 | 2026-09-01 | 2026-07-30 |
| The ConCERN Intervention for Loved Ones of Those With Opioid Use Disorder ConCERN intervention, Treatment as Usual - Opioid Use Disorder | Not applicable | Not yet recruiting | University of Michigan | 700 | 2026-09-01 | 2026-08-31 |
| Increasing Law Enforcement Application of Automated External Defibrillators (AED)s for Cardiac Arrest AED training adjunct - Heart Arrest, Out-Of-Hospital, Defibrillators | Not applicable | Enrolling by invitation | Wayne State University | 30 | 2026-07-14 | 2026-08-19 |
| Pilot Study of Prenatal Choline Supplementation Placebo, Choline bitartrate - Brain Development, Choline Nutrition | Phase 2 | Recruiting | Wayne State University | 50 | 2026-07-08 | 2026-07-14 |
| Peer-Delivered Behavioral Activation in a CCBHC Peer Activate, Peer-delivered non-specific services - Major Depressive Disorder, Substance Use Disorders | Not applicable | Recruiting | Wayne State University | 250 | 2026-05-01 | 2026-04-17 |
| Timing of Opioid Administration and Postoperative Respiratory Depression. Respiratory volume monitoring - Respiratory Complications, Opioid Induced Respiratory Depression | Recruiting | Wayne State University | 52 | 2026-02-01 | 2026-07-16 | |
| Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study 1-(2-[+F]fluoroethyl)-L-tryptophan - PTSD, Suicidal Thoughts and Behaviors | Enrolling by invitation | Wayne State University | 100 | 2026-01-01 | 2026-10-21 | |
| Phase 1 Trial of Arginine Hydrochloride for the Management of Diabetic Ketoacidosis in Type 2 Diabetes Arginine hydrochloride, Sodium Chloride 0.9% - Diabetes (DM), Diabetic Ketoacidosis | Phase 1 / Phase 2 | Recruiting | David K Carroll | 60 | 2025-12-19 | 2026-02-12 |
| Examining the Impact of the Parenting Young Children Check-up The Parenting Young Children Check-up - Behavioral Health, Disruptive Behaviors | Early Phase 1 | Recruiting | Wayne State University | 40 | 2025-11-06 | 2026-07-29 |
| Cannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder Low-Dose Cannabidiol, Placebo Matched to Moderate-Dose Cannabidiol, Moderate-Dose Cannabidiol - Generalized Anxiety Disorder (GAD), Anxiety Disorders | Phase 3 | Recruiting | Wayne State University | 90 | 2025-11-03 | 2026-10-21 |
| Neurofeedback and Well-Being Among People With Co-Occurring Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms Neuroptimal (Zengar, Inc.) Neurofeedback - Well-Being, Psychological, Mood Disturbance | Not applicable | Recruiting | Wayne State University | 20 | 2025-11-01 | 2026-08-19 |
| Testing the Impact of the Parenting Young Children Check-up Parenting Young Children Check-up - Behavioral Health, Disruptive Behaviors | Early Phase 1 | Recruiting | Wayne State University | 50 | 2025-11-01 | 2026-08-06 |
| Efficacy and Safety of Perampanel in the Treatment of Refractory Status Epilepticus Perampanel - Refractory Status Epilepticus | Phase 4 | Terminated | Wayne State University | 1 | 2025-10-10 | 2025-10-14 |
| VR Stimulation of Exercise Response in Sedentary Humans 20 minutes cycling exercise, Virtual Reality - Prolonged Inactivity, Metabolic Syndrome | Not applicable | Recruiting | Wayne State University | 48 | 2025-09-30 | 2025-12-23 |
| Warrior CARE: Cannabis Behavioral Health Tetrahydrocannabinol, Cannabidiol, Placebo - Post Traumatic Stress Disorder, Cannabis Use | Phase 1 / Phase 2 | Recruiting | Wayne State University | 500 | 2025-09-22 | 2026-08-07 |
| FOCUS ON US: Adapting the FOCUS Program for Sexual and Gender Minority (SGM) Cancer Patients and Caregivers FOCUS ON US - Cancer Support, Oncology Patients | Not applicable | Recruiting | Charles Kamen | 160 | 2025-09-04 | 2026-08-17 |
Showing 20 of 333. Sign in to see all of them.
Opioid-Related Disorders (18) · Substance-Related Disorders (16) · Stress Disorders, Post-Traumatic (14) · Hypertension (13) · Diabetes Mellitus, Type 1 (10) · Motor Activity (10) · Anxiety Disorders (8) · Heart Failure (8) · Heroin Dependence (8) · Marijuana Abuse (8) · Multiple Sclerosis (8) · Chronic Pain (7) · Depression (7) · Spinal Cord Injuries (7) · Diabetes Mellitus (6)
Therapeutics (7) · Dronabinol (6) · Yohimbine (6) · Hydrocortisone (5) · Bupivacaine (4) · Motivational Interviewing (4) · Sodium Chloride (4) · Sugars (4) · Buprenorphine (3) · Cognitive Behavioral Therapy (3) · Educational Status (3) · Exercise (3) · Neurofeedback (3) · Art Therapy (2) · Cannabidiol (2)
United States (295) · Canada (7) · Sweden (4) · Thailand (4) · United Kingdom (3) · Italy (2) · South Africa (2) · Albania (1) · Australia (1) · Austria (1) · Brazil (1) · China (1) · Czechia (1) · France (1) · Germany (1)
Mark Greenwald, PhD (15) · Leslie Lundahl, PhD (7) · Mark K Greenwald, PhD (6) · Christos Coutifaris, MD (5) · Esther Eisenberg, MD, MPH (5) · Heping Zhang, PhD (5) · Michael Diamond, MD (5) · Nanette Santoro, MD (5) · Peter Casson, MD (5) · Richard Legro, MD (5) · Robert Brzyski, MD, PhD (5) · Steven J Ondersma, Ph.D. (5) · Sylvie Naar-King, Ph.D. (5) · Mark A Lumley, PhD (4) · Abbot Laptook, MD (3)
PMID 25630964, PMID 25911999, PMID 22339949, PMID 15925264, PMID 26354094, PMID 26413816, PMID 27402910, PMID 27436749, PMID 29102040, PMID 29778387, PMID 30085176, PMID 33190149, PMID 34180998, PMID 35125179, PMID 39672366, PMID 10511011, PMID 10588403, PMID 10913502, PMID 11072948, PMID 13519856, PMID 15729953, PMID 15983308, PMID 16260435, PMID 16322140, PMID 16322274, PMID 16675714, PMID 16881786, PMID 17074351, PMID 17236741, PMID 17295576, PMID 17635953, PMID 17659062, PMID 17999405, PMID 18056557, PMID 18512816, PMID 18566340, PMID 19167733, PMID 19273743, PMID 19383981, PMID 19389332, PMID 19507756, PMID 19666684, PMID 19683484, PMID 20535796, PMID 20881947, PMID 20887691, PMID 20935292, PMID 21097734, PMID 21430238, PMID 21645894
R01DA015462 (4), R01DK059067 (3), U10HD055925 (3), R01DA022243 (2), R01DA032678 (2), R21DA014621 (2), R21DA019236 (2), F31DA040369 (1), K01MH110600 (1), K23DA000516 (1), P50ES012395 (1), P50HL110790 (1), R01AG051628 (1), R01AG056102 (1), R01AG059683 (1)