25 recruiting, 14 not yet recruiting, 12 completed, 5 enrolling by invitation. 34 Not applicable, 3 Phase 2, 2 Phase 4, 1 Phase 1, 1 Phase 3.
Follow Bipolar Disorder (BD): new trials by email Literature Review of Bipolar Disorder (BD) trials Research Report on Bipolar Disorder (BD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN) Semaglutide (SEMA), Exercise module, Anti-inflammatory diet module - Severe Mental Illness, Depression / Major Depressive Disorder | Not applicable | Not yet recruiting | Ludwig-Maximilians - University of Munich | 140 | 2028-10-01 | 2026-05-14 |
| BAROMETRE : Study on the Prognosis and Course of Individuals With Bipolar Spectrum Disorder Structured clinical follow-up and psychometric assessment - Bipolar Disorder (BD) | Not yet recruiting | University Hospital, Angers | 60 | 2026-11-01 | 2026-10-14 | |
| Evaluating the PolarUs App in People With Bipolar Disorder PolarUs Mobile App - Bipolar Disorder (BD), Quality of Life (QOL) | Not applicable | Not yet recruiting | University of British Columbia | 504 | 2026-11-01 | 2026-10-22 |
| Testing a New Gold Nanoparticle-Based Lithium Delivery Method for Bipolar Disorder in Laboratory Models Peripheral blood sampling for PBMC isolation - Bipolar Disorder (BD), Bipolar Disorder (BPD) | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 20 | 2026-10-01 | 2026-07-29 |
| Pramipexole vs Placebo Treatment in Bipolar Disorder With Anhedonic Depression Pramipexole, Placebo - Bipolar Disorder (BD) | Phase 3 | Recruiting | Daniel Lindqvist | 126 | 2026-10-01 | 2026-10-22 |
| Medication Adherence in Severe Mental Illness: a Promotion Program Telehealth Psychoeducational Adherence Program - Treatment Adherence and Compliance, Severe Mental Disorders | Not applicable | Not yet recruiting | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 1640 | 2026-09-01 | 2026-03-03 |
| Time Restricted Eating (TRE) in Bipolar Disorder Time Restricted Eating - Bipolar Disorder (BD), Bipolar Disorder Depression | Not applicable | Recruiting | Massachusetts General Hospital | 40 | 2026-09-01 | 2026-10-07 |
| Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment Blood sampling, lumbar puncture, stool sampling, skin microbiopsy and psychometrics scales - Schizophrenia, Treatment Resistant Depression (TRD) | Not applicable | Recruiting | Centre Hospitalier St Anne | 700 | 2026-08-20 | 2026-09-21 |
| Neuromodulation of Mood Switch Circuitry in Bipolar Disorder MagVenture MagPro TMS system, Sham Stimulation - Bipolar Disorder (BD), Bipolar 1 Depression | Phase 4 | Recruiting | Weill Medical College of Cornell University | 62 | 2026-08-03 | 2026-09-23 |
| Identifying Biomarkers of Response to Digital Interventions for Mood Disorders Online Cognitive Behavioural Therapy - Depression / Major Depressive Disorder, Bipolar Disorder (BD) | Not applicable | Enrolling by invitation | Centre for Addiction and Mental Health | 200 | 2026-07-28 | 2026-08-27 |
| Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT) Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT) - Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder | Phase 2 | Recruiting | Joshua Rosenblat | 120 | 2026-07-16 | 2026-07-29 |
| Transcranial Photobiomodulation for Bipolar Depression Vielight Neuro Rx Gamma, Sham Device - Bipolar, Bipolar Disorder (BD) | Not applicable | Not yet recruiting | Vielight Inc. | 40 | 2026-07-01 | 2026-04-03 |
| French Minds Cohort: a French Longitudinal and Multimodal Cohort of Patients With Major Mood Disorders, Psychotic Disorders, Autism Spectrum Disorders, and Healthy Controls 3T Brain MRI, Biological Sampling, Clinical, Cognitive and Digital Assessments - Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP) | Not applicable | Recruiting | Fondation FondaMental | 3000 | 2026-06-11 | 2026-10-19 |
| Multimodal Intervention to Support Hospital-to-Community Transition in Bipolar Disorder Group-Based Psychoeducation, Peer Support, Personalized Support for Community Healthcare Provider - Bipolar Disorder (BD), Psychosis | Not applicable | Recruiting | McMaster University | 10 | 2026-06-01 | 2026-10-06 |
| Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder Relationship-use questionnaire - Borderline Personality Disorder, Borderline Personality Disorder (BPD) | Not applicable | Recruiting | University Hospital, Montpellier | 194 | 2026-06-01 | 2026-06-22 |
| Research on the Efficacy and Safety of Targeted Suprachiasmatic Nucleus Electrical Stimulation for Improving Metabolic Disorders in Patients With Stable Bipolar Disorder Comorbid With Obesity Temporal Interference Stimulation, Sham Temporal Interference Stimulation Arm Description - Bipolar Disorder (BD) | Not applicable | Recruiting | First Affiliated Hospital of Zhejiang University | 70 | 2026-04-27 | 2026-05-27 |
| A Study of Home-use Brain Stimulation to Treat Bipolar Depression Flow FL-100 tDCS headset - Bipolar Disorder (BD) | Not applicable | Recruiting | King's College London | 212 | 2026-04-24 | 2026-04-29 |
| PROgram To Enhance Cardiovascular Risk Trough an Intervention of Nutrition in Bipolar Disorder Nutritional intervention - Bipolar Depression, Bipolar Disorder (BD) | Not applicable | Recruiting | University of Sao Paulo | 88 | 2026-04-01 | 2026-03-02 |
| Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder Major Depressive Disorder, Mood Disorders | Not yet recruiting | Karolinska Institutet | 600 | 2026-04-01 | 2026-02-23 | |
| An Exploratory Study on the Prediction of Recurrence Risk of Bipolar Disorder Using Sentiment Analysis Technology Based on Multi-modal Feature Fusion This is an observational study with no intervention. - Bipolar Disorder (BD), Healthy Control | Recruiting | Shanghai Mental Health Center | 400 | 2026-04-01 | 2026-05-07 |
Showing 20 of 59. Sign in to see all of them.
Bipolar Disorder (59) · Schizophrenia (13) · Depressive Disorder, Major (11) · Cognitive Dysfunction (4) · Mood Disorders (4) · Psychotic Disorders (4) · Autism Spectrum Disorder (3) · Depression (3) · Depressive Disorder, Treatment-Resistant (3) · Mental Disorders (3) · Obsessive-Compulsive Disorder (3) · Alzheimer Disease (2) · Anhedonia (2) · Borderline Personality Disorder (2) · Dementia (2)
Bipolar and Related Disorders (58) · Mental Disorders (56) · Mood Disorders (55) · Schizophrenia Spectrum and Other Psychotic Disorders (14) · Behavior (13) · Depressive Disorder (12) · Nervous System Diseases (10) · Pathological Conditions, Signs and Symptoms (10) · Signs and Symptoms (9) · Neurocognitive Disorders (7) · Behavioral Symptoms (6) · Neurologic Manifestations (6) · Neurobehavioral Manifestations (5) · Brain Diseases (4) · Central Nervous System Diseases (4)
Blood Specimen Collection (2) · Standard of Care (2) · Therapeutics (2) · Biofeedback, Psychology (1) · Data Collection (1) · Electroconvulsive Therapy (1) · Flumazenil (1) · Ketamine (1) · Lithium (1) · Lurasidone Hydrochloride (1) · MD1 (1) · Magnetoencephalography (1) · Mental Status and Dementia Tests (1) · Midazolam (1) · Neurofeedback (1)
Centre Hospitalier St Anne (3) · Centre for Addiction and Mental Health (2) · First Affiliated Hospital of Zhejiang University (2) · Peking University (2) · University Hospital, Montpellier (2) · University of British Columbia (2) · Akrivia Health (1) · Anders Jørgensen (1) · Assistance Publique Hopitaux De Marseille (1) · Assiut University (1) · Babes-Bolyai University (1) · Butler Hospital (1) · Daniel Lindqvist (1) · Dokuz Eylul University (1) · Dong-Wook Kim (1)
United States (9) · Canada (7) · Turkey (Türkiye) (7) · China (6) · France (6) · Denmark (4) · South Korea (3) · Italy (2) · United Kingdom (2) · Austria (1) · Brazil (1) · Chile (1) · Germany (1) · Netherlands (1) · Norway (1)
Antoine Douaihy, MD (1) · Antonio Vita, MD, PhD (1) · Atta-ul Raheem R Chaudhry, B.Sc. (Hons.), M.B.B.S. (1) · Daniel Lindqvist, PhD, MD (1) · Dong-Wook Kim, M.D. (1) · Fei Wang (1) · Gabriele Sani (1) · Heon-Jeong Lee, Professor (1) · Immanuel Elbau, MD, PhD (1) · Joshua D. Rosenblat, MD, MSc (1) · Julian Macoveanu, PhD (1) · Julianna Olah, B.Sc., M.A., M.Sc., Ph.D. (1)
PMID 11532527, PMID 15725966, PMID 19666076, PMID 20060416, PMID 22854028, PMID 22949289, PMID 23714262, PMID 26468988, PMID 28078204, PMID 31077729, PMID 31150942, PMID 31877761, PMID 33761085, PMID 34639510, PMID 35483736, PMID 36573651, PMID 37592949, PMID 37622055, PMID 41225581, PMID 41362421, PMID 41406148
2025 (1)