364 completed, 96 unknown, 84 recruiting, 29 terminated. 634 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 634 | Completed 364, Unknown 96, Recruiting 84, Terminated 29, Not yet recruiting 24, Active not recruiting 18, Withdrawn 11, Enrolling by invitation 5, Suspended 3 |
Follow Bipolar Disorder: new trials by email Literature Review of Bipolar Disorder trials Research Report on Bipolar Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN) Semaglutide (SEMA), Exercise module, Anti-inflammatory diet module - Severe Mental Illness, Depression / Major Depressive Disorder | Not applicable | Not yet recruiting | Ludwig-Maximilians - University of Munich | 140 | 2028-10-01 | 2026-05-14 |
| Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders Soterix 1x1 tES mini-CT - Bipolar Disorder, Bipolar and Related Disorders | Not applicable | Not yet recruiting | VA Office of Research and Development | 138 | 2027-06-01 | 2026-09-28 |
| Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical Applications repetitive transcranial magnetic stimulation (rTMS) - Schizophrenia, Bipolar Disorder | Not applicable | Not yet recruiting | Central South University | 400 | 2027-01-01 | 2026-03-04 |
| Evaluating the Impact of Ketogenic Therapy on Symptom Severity and Metabolic Side Effect Profile Among Individuals Living With Bipolar Disorder in A Rural Southern Catchment Area Ketogenic foodstuffs, Standard of Care Oral antipsychotics, Standard of care long acting injectable medication for bipolar disorder - Bipolar Disorder | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 100 | 2026-11-01 | 2026-10-07 |
| A Mobile App to Support Mood, Daily Routines and Medication Adherence in Adults With Severe Mental Illness MoodSync, Standard care - Severe Mental Illness, Bipolar Disorder | Not applicable | Not yet recruiting | Alexandria University | 60 | 2026-11-01 | 2026-10-16 |
| Evaluating the PolarUs App in People With Bipolar Disorder PolarUs Mobile App - Bipolar Disorder (BD), Quality of Life (QOL) | Not applicable | Not yet recruiting | University of British Columbia | 504 | 2026-11-01 | 2026-10-22 |
| Testing a New Gold Nanoparticle-Based Lithium Delivery Method for Bipolar Disorder in Laboratory Models Peripheral blood sampling for PBMC isolation - Bipolar Disorder (BD), Bipolar Disorder (BPD) | Not applicable | Not yet recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 20 | 2026-10-01 | 2026-07-29 |
| Effect of Occupational Therapy on Psychosocial Parameters and Functioning in Individuals With Severe Mental Illness Occupational Therapy Group Intervention - Schizophenia Disorder, Severe Mental Illness | Not applicable | Not yet recruiting | Biruni University | 50 | 2026-10-01 | 2026-10-16 |
| Safety and Feasibility of DBS for Bipolar Depression Medtronic Percept PC DBS system - Bipolar I Disorder, Bipolar Depression | Not applicable | Recruiting | Icahn School of Medicine at Mount Sinai | 5 | 2026-09-21 | 2026-09-22 |
| Senyo Health App - Comorbid Alcohol Use Disorder Treatment in Individuals With Bipolar Disorder Using a Telehealth Collaborative Care Platform Senyo Health App - Bipolar Disorder | Not applicable | Not yet recruiting | Mayo Clinic | 40 | 2026-09-16 | 2026-07-31 |
| Medication Adherence in Severe Mental Illness: a Promotion Program Telehealth Psychoeducational Adherence Program - Treatment Adherence and Compliance, Severe Mental Disorders | Not applicable | Not yet recruiting | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 1640 | 2026-09-01 | 2026-03-03 |
| Time Restricted Eating (TRE) in Bipolar Disorder Time Restricted Eating - Bipolar Disorder (BD), Bipolar Disorder Depression | Not applicable | Recruiting | Massachusetts General Hospital | 40 | 2026-09-01 | 2026-10-07 |
| Treatment Resistance in Psychiatric Disorders: the Search for Biological Markers Predictive of Response to Treatment Blood sampling, lumbar puncture, stool sampling, skin microbiopsy and psychometrics scales - Schizophrenia, Treatment Resistant Depression (TRD) | Not applicable | Recruiting | Centre Hospitalier St Anne | 700 | 2026-08-20 | 2026-09-21 |
| Enhancing Veteran-Clinical Collaboration in VA PRRCs Collaborative Decision Skills Training, Leveling Up - Schizophrenia, Schizoaffective Disorder | Not applicable | Recruiting | VA Office of Research and Development | 119 | 2026-08-12 | 2026-08-19 |
| Psychophysiological Responses to Six Single-Session Self-Regulation Interventions in a Female Adult With ADHD and Stabilized Bipolar Disorder Moderate-Intensity Aerobic Exercise on Cycloergometer, Cyclic Sighing, Aromatherapy - ADHD - Attention Deficit Disorder With Hyperactivity, Bipolar Affective Disorder; Remission in | Not applicable | Recruiting | Poznan University of Physical Education | 1 | 2026-07-31 | 2026-08-03 |
| Identifying Biomarkers of Response to Digital Interventions for Mood Disorders Online Cognitive Behavioural Therapy - Depression / Major Depressive Disorder, Bipolar Disorder (BD) | Not applicable | Enrolling by invitation | Centre for Addiction and Mental Health | 200 | 2026-07-28 | 2026-08-27 |
| Transcranial Photobiomodulation for Bipolar Depression Vielight Neuro Rx Gamma, Sham Device - Bipolar, Bipolar Disorder (BD) | Not applicable | Not yet recruiting | Vielight Inc. | 40 | 2026-07-01 | 2026-04-03 |
| French Minds Cohort: a French Longitudinal and Multimodal Cohort of Patients With Major Mood Disorders, Psychotic Disorders, Autism Spectrum Disorders, and Healthy Controls 3T Brain MRI, Biological Sampling, Clinical, Cognitive and Digital Assessments - Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP) | Not applicable | Recruiting | Fondation FondaMental | 3000 | 2026-06-11 | 2026-10-19 |
| Functional Magnetic Resonance Imaging Study of Inhibitory Control in Bipolar Disorder and Major Depressive Disorder Analysis of inhibitory control - Bipolar Disorder, Major Depressive Disorder | Not applicable | Not yet recruiting | CHU de Reims | 120 | 2026-06-01 | 2026-03-31 |
| Multimodal Intervention to Support Hospital-to-Community Transition in Bipolar Disorder Group-Based Psychoeducation, Peer Support, Personalized Support for Community Healthcare Provider - Bipolar Disorder (BD), Psychosis | Not applicable | Recruiting | McMaster University | 10 | 2026-06-01 | 2026-10-06 |
Showing 20 of 634. Sign in to see all of them.
Schizophrenia (189) · Psychotic Disorders (113) · Depressive Disorder, Major (110) · Depression (107) · Mental Disorders (67) · Mood Disorders (36) · Depressive Disorder (32) · Anxiety Disorders (27) · Depressive Disorder, Treatment-Resistant (17) · Mania (17) · Cognitive Dysfunction (16) · Stress Disorders, Post-Traumatic (16) · Substance-Related Disorders (15) · Metabolic Syndrome (14)
Bipolar and Related Disorders (629) · Mood Disorders (598) · Mental Disorders (567) · Schizophrenia Spectrum and Other Psychotic Disorders (208) · Behavior (192) · Behavioral Symptoms (125) · Depressive Disorder (111) · Pathological Conditions, Signs and Symptoms (71) · Signs and Symptoms (61) · Nervous System Diseases (49) · Chemically-Induced Disorders (36) · Neurologic Manifestations (36) · Nutritional and Metabolic Diseases (30) · Health Behavior (28) · Neurobehavioral Manifestations (27)
Therapeutics (28) · Transcranial Magnetic Stimulation (16) · Cognitive Behavioral Therapy (13) · Exercise (11) · Lithium (9) · Transcranial Direct Current Stimulation (9) · Quetiapine Fumarate (8) · Blood Specimen Collection (7) · Diet, Ketogenic (7) · Ultraviolet Therapy (7) · Cognitive Remediation (6) · Educational Status (6) · Salvage Therapy (6) · Standard of Care (6) · Aripiprazole (5)
Massachusetts General Hospital (22) · Centre for Addiction and Mental Health (17) · Mclean Hospital (17) · Dartmouth-Hitchcock Medical Center (15) · VA Office of Research and Development (15) · University of Michigan (14) · University of Pittsburgh (13) · Stanford University (12) · Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital (11) · First Affiliated Hospital of Zhejiang University (9) · University of Washington (9) · Case Western Reserve University (8) · Sunnybrook Health Sciences Centre (7) · University Hospital, Montpellier (7) · University of Sao Paulo (7)
United States (276) · Canada (57) · France (53) · Denmark (29) · China (28) · Spain (17) · Turkey (Türkiye) (17) · United Kingdom (17) · Brazil (13) · Germany (13) · Norway (11) · Taiwan (8) · Australia (6) · Israel (6) · Italy (6)
Benjamin I Goldstein, MD, PhD (6) · Martha Sajatovic, MD (6) · Brandon Gaudiano, PhD (3) · Dror Ben-Zeev, PhD (3) · Elizabeth Lippard, PhD (3) · Herbert Y Meltzer, M.D. (3) · Maria Faurholt-Jepsen, MD (3) · Tina R Goldstein, PhD (3) · Amy M Kilbourne, PhD, MPH (2) · Amy M. Kilbourne, PhD MPH (2) · Benedikt L Amann, MD (2) · Brent P Forester, MD (2) · Cynthia Burton, PhD (2) · Daniel Blumberger, MD, MSc (2) · David M Kreindler, MD (2)
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