47 completed, 7 unknown, 6 terminated, 5 active not recruiting. 65 Not applicable, 3 Phase 3, 2 Early Phase 1, 2 Phase 2, 1 Phase 1.
Follow Cognitive Remediation: new trials by email Literature Review of Cognitive Remediation trials Research Report on Cognitive Remediation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Hand Rehabilitation on Cognitive Function in Patients With PD Hand Sensorimotor Rehabilitation, Cognitive Remediation - PARKINSON DISEASE (Disorder) | Not applicable | Not yet recruiting | Isfahan University of Medical Sciences | 48 | 2026-08-23 | 2026-07-24 |
| Evaluating the Feasibility, Acceptability, and Initial Clinical Effectiveness of Implementing a Cognitive Remediation Program Within Psychiatric Services. Cognitive remediation - Severe and Persistent Mental Illness | Not applicable | Not yet recruiting | The Royal Ottawa Mental Health Centre | 87 | 2026-03-01 | 2026-03-03 |
| The Effect of Single Lung Ventilation Duration and Intraoperative Brain Oxygenation on Cognitive Function and Postoperative Pain in Geriatric Patients Cognitive Remediation, Pain Medicine - Thoracic Anesthesia, Geriatric Anesthesia | Not yet recruiting | Ankara Ataturk Sanatorium Training and Research Hospital | 30 | 2026-01-15 | 2026-01-15 | |
| Cognitive Remediation of Working Memory Post Head Trauma therapeutic education, tDCS, cognitive remediation - Head Trauma | Not applicable | Recruiting | University Hospital, Toulouse | 9 | 2025-11-06 | 2026-08-07 |
| FACE Phase II (a Stage II Trial) Cognitive Remediation, Cognitive Remediation II - MCI, Subjective Cognitive Decline (SCD) | Phase 1 / Phase 2 | Recruiting | Stanford University | 80 | 2025-10-31 | 2026-04-24 |
| CRacking the HEterogeneity of Social Outcome Through Neuropsychophysiological Profiles Cognitive Remediation - Schizophenia Disorder | Not yet recruiting | IRCCS San Raffaele | 100 | 2025-05-01 | 2025-03-11 | |
| Cognitive Remediation in Schizophrenia: Efficacy and Role of Neuroplasticity in "Top-down" and "Bottom-up" Mechanisms Cognitive Remediation - Schizophrenia | Not applicable | Unknown | University of Chile | 160 | 2024-06-01 | 2024-07-01 |
| Cognitive Remediation and Transcranial Direct Current Stimulation in Severe Mental Illness (SMI) Cognitive remediation + active tDCS, Cognitive remediation + sham tDCS - Severe Mental Illness | Not applicable | Active not recruiting | University of Groningen | 126 | 2024-05-06 | 2026-06-26 |
| Enhanced Coordinated Specialty Care for Early Psychosis Care Coordination, Individual Peer Support, Digital Outreach - Psychosis, Schizophrenia | Not applicable | Recruiting | Mclean Hospital | 350 | 2024-02-01 | 2026-02-27 |
| Telepsychiatry for Social Isolation in Youths Cognitive Behavioral Therapy (CBT), Cognitive Remediation (CR) - Social Isolation, Psychosocial Problem | Not applicable | Unknown | Azienda Ospedaliera Universitaria Integrata Verona | 80 | 2023-09-01 | 2024-07-30 |
| Examining the Efficacy of a Virtual Reality Cognitive Remediation Program for People Living With Psychosis Cognitive Remediation, Active Control - Psychotic Disorders, Schizophrenia | Not applicable | Recruiting | The Royal Ottawa Mental Health Centre | 52 | 2023-07-31 | 2026-04-16 |
| Promoting Cognitive Health in Schizophrenia Cognitive remediation, MetaCognitive Training - Schizophrenia, Cognition | Not applicable | Completed | Douglas Mental Health University Institute | 192 | 2023-04-15 | 2026-08-27 |
| Evaluation of Cognitive Management for Chemobrain in Patients Treated for Breast Cancer. Cognitive remediation - Breast Cancer | Not applicable | Active not recruiting | Institut Bergonié | 164 | 2023-02-01 | 2025-08-13 |
| Benefits of Combining MCT With CR in the Recovery of Patients With Psychotic Spectrum Disorders Cognitive Remediation (REHACOP), Metacognitive Training (MCT) - Schizophrenia, Schizophreniform Disorders | Not applicable | Unknown | Universitat Autonoma de Barcelona | 160 | 2022-09-01 | 2024-05-23 |
| Integral Cognitive Remediation for Depression INCREM, Psychoeducation - Major Depressive Disorder (MDD) | Not applicable | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 101 | 2021-09-19 | 2025-06-11 |
| Cognitive Stimulation Therapy - Effects on Cognitive and Functional Domains in Dementia - A Retrospective Data Review Cognitive Remediation - Dementia | Completed | Northumbria University | 160 | 2021-09-01 | 2025-05-31 | |
| tDCS and Executive Function Training for Schizophrenia Transcranial direct current stimulation, Executive function training - Schizophrenia, Schizophrenia Spectrum Disorder | Not applicable | Withdrawn | University of Toronto | 2021-05-01 | 2024-07-30 | |
| Community-based Cognitive Remediation and tDCS to Enhance Seniors' Function and Mental Health Cognitive Remediation and Transcranial Direct Current Stimulation - Mental Health Disorder, Aging | Not applicable | Active not recruiting | Centre for Addiction and Mental Health | 18 | 2021-01-27 | 2026-07-14 |
| Cognitive Remediation in Forensic Mental Health Care Cognitive Remediation, Active Control - Psychotic Disorders, ADHD | Not applicable | Recruiting | The Royal Ottawa Mental Health Centre | 30 | 2020-02-10 | 2025-12-12 |
| Cerebral Impact of Cognitive Remediation for People Suffering From Schizophrenia Cognitive remediation, psychosocial rehabilitation - Schizophrenia | Not applicable | Terminated | Hôpital le Vinatier | 78 | 2019-12-17 | 2024-02-14 |
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Schizophrenia (39) · Psychotic Disorders (25) · Bipolar Disorder (7) · Cognitive Dysfunction (6) · Mental Disorders (6) · Depression (5) · Attention Deficit Disorder with Hyperactivity (4) · Depressive Disorder, Major (4) · Schizophrenia Spectrum and Other Psychotic Disorders (3) · Substance-Related Disorders (3) · Antisocial Personality Disorder (2) · Anxiety Disorders (2) · Mood Disorders (2) · Neurobehavioral Manifestations (2) · Parkinson Disease (2)
Centre for Addiction and Mental Health (4) · New York State Psychiatric Institute (4) · Universitätsklinikum Hamburg-Eppendorf (4) · VA Office of Research and Development (4) · Hôpital le Vinatier (3) · The Royal Ottawa Mental Health Centre (3) · Hartford Hospital (2) · IRCCS San Raffaele (2) · Queen's University (2) · US Department of Veterans Affairs (2) · University of Arizona (2) · University of California, Los Angeles (2) · Albert Einstein College of Medicine (1) · Ankara Ataturk Sanatorium Training and Research Hospital (1) · Azienda Ospedaliera Universitaria Integrata Verona (1)
United States (32) · Canada (13) · France (5) · Germany (4) · Spain (4) · Denmark (2) · Italy (2) · United Kingdom (2) · Chile (1) · Netherlands (1) · Norway (1) · Slovenia (1) · Turkey (Türkiye) (1)
Steffen Moritz, PhD (3) · Alice Medalia, PhD (2) · Maria J Portella, Dr (2) · Morris D Bell, PhD (2) · Adeline Julien (1) · Alice A Medalia, PhD (1) · Ana Barajas Velez (1) · Angela Golas, MD (1) · Angus W MacDonald, Ph.D. (1) · Anil Chacko, PhD (1) · Anthony O Ahmed, PhD (1) · Anu Raj, Psy.D (1) · Benoit H Mulsant, MD (1)
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