124 completed, 32 unknown, 19 terminated, 12 recruiting. 204 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 204 | Completed 124, Unknown 32, Terminated 19, Recruiting 12, Not yet recruiting 6, Enrolling by invitation 5, Withdrawn 4, Active not recruiting 1, Suspended 1 |
Follow Basal Ganglia Diseases: new trials by email Literature Review of Basal Ganglia Diseases trials Research Report on Basal Ganglia Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Gastrointestinal Dopamine Decarboxylase and Levodopa Pharmacokinetics Levodopa (L-dopa) - Parkinson's Disease | Phase 4 | Not yet recruiting | Beth Israel Deaconess Medical Center | 40 | 2027-07-01 | 2026-08-28 |
| Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease mirabegron, Exercise-based behavioral therapy - Overactive Bladder, Parkinson Disease | Phase 4 | Not yet recruiting | VA Office of Research and Development | 146 | 2026-11-09 | 2026-10-27 |
| Metformin in Parkinson's Disease: Safety and Efficacy Metformin 500mg - Parkinsons Disease (PD) | Phase 4 | Not yet recruiting | Jinnah Medical & Dental College | 70 | 2026-08-28 | 2026-09-09 |
| Effects of Lemborexant on Motor-sleep Comorbidity in Parkinson's Disease Lemborexant, placebo - Parkinson's Disease, Insomnia | Phase 4 | Not yet recruiting | YangPan | 44 | 2026-08-19 | 2026-06-11 |
| Pilot Deprescribing of Antimuscarinic Overactive Bladder Medications in Parkinson Disease Overactive bladder antimuscarinic deprescribing - Parkinson Disease (PD) | Phase 4 | Not yet recruiting | Corporal Michael J. Crescenz VA Medical Center | 20 | 2026-06-01 | 2026-06-04 |
| A 12-Week Study of Flexilev With the OraFID Device and App in Parkinson's Patients OraFID dosing device, Levodopa/Carbidopa minitablets delivered via OraFID dosing device - PARKINSON DISEASE (Disorder) | Phase 4 | Recruiting | Navamedic AB | 58 | 2026-05-25 | 2026-09-24 |
| EFficacy and safEty of cRisugabalin on nocipLastic paIn in Patients With Parkinson's Disease (RELIEF-PD): a Multicentre, Double-blind, Randomised Controlled Trial Crisugabalin, Placebo - PARKINSON DISEASE (Disorder) | Phase 4 | Active not recruiting | Guangdong Provincial People's Hospital | 166 | 2026-03-13 | 2026-09-14 |
| Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia Syn-One skin biopsy, Multi modal MRI, Assessment of dynamic EEG features over 48-hour periods across all study aims - Dementia With Lewy Bodies, Parkinson Disease Dementia | Phase 4 | Recruiting | Virginia Commonwealth University | 120 | 2025-12-08 | 2026-03-06 |
| BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease CREXONT ER - Parkinson Disease | Phase 4 | Recruiting | The Cleveland Clinic | 22 | 2025-07-24 | 2026-10-15 |
| A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease CREXONT ER - Parkinson Disease | Phase 4 | Recruiting | Impax Laboratories, LLC | 220 | 2025-02-12 | 2025-08-24 |
| Vortioxetine for Depressive Symptoms and Freezing of Gait in Parkinson Disease Vortioxetine (tablet) - Parkinson Disease, Idiopathic, Freezing of Gait | Phase 4 | Not yet recruiting | Marianna Amboni | 40 | 2025-02-01 | 2025-02-06 |
| Imaging Biomarkers of FOG Response to DBS fMRI - Freezing of Gait Symptoms in Parkinson's Disease, Deep Brain Stimulation | Phase 4 | Recruiting | Medical University of South Carolina | 54 | 2024-11-11 | 2026-08-10 |
| Anti-Diabetic Medications to Fight PD and LBD Sitagliptin, Dapagliflozin, Placebo - Lewy Body Dementia, Parkinson Disease | Phase 4 | Completed | Mayo Clinic | 18 | 2024-05-07 | 2026-01-28 |
| Real World Effectiveness and Safety of Deutetrabenazine in Adult Chinese Participants With Huntington's Disease (HD) Chorea in China Deutetrabenazine - Huntington's Disease, Chorea | Phase 4 | Completed | Teva Branded Pharmaceutical Products R&D LLC | 50 | 2024-02-02 | 2026-08-27 |
| Motor Function Efficacy of Pharmacological Treatments Targeting Energy Metabolism, in Parkinson's Patients Terazosin - Parkinson Disease, Gait Analysis | Phase 4 | Unknown | I.R.C.C.S. Fondazione Santa Lucia | 50 | 2023-12-01 | 2023-09-22 |
| Basic and Clinical Studies of Levodopa/Carbidopa/Entacapone in the Treatment of Early Parkinson's Disease levodopa/carbidopa/entacapone - Parkinson Disease | Phase 4 | Unknown | Second Affiliated Hospital of Soochow University | 60 | 2023-11-15 | 2024-02-01 |
| DBS and Levodopa for Treating Freezing of Gait in Parkinson's Disease STIM ON plus, MED ON plus - Freezing of Gait, Parkinson Disease | Phase 4 | Recruiting | IRCCS Istituto delle Scienze Neurologiche di Bologna | 20 | 2023-10-10 | 2024-03-18 |
| Comparison of Dopamin Level in Idiopathic Parkinson's Patients Levodopa - Parkinson Disease, Treatment Adherence | Phase 4 | Unknown | Ankara Ataturk Sanatorium Training and Research Hospital | 96 | 2023-10-01 | 2023-11-28 |
| Personalized Real-Time DBS and PD Mechanisms Neurostimulation, Carbidopa 25/Levodopa 100Mg Tab - Parkinson Disease | Phase 4 | Recruiting | David Escobar | 25 | 2023-08-29 | 2026-08-20 |
| MIBG in Aging and Neurologic Disorders meta-iodobenzylguanidine (MIBG) (123I), 123I-MIBG scintigraphy - Lewy Body Disease, Dementia | Phase 4 | Enrolling by invitation | Mayo Clinic | 50 | 2023-05-08 | 2026-07-30 |
Showing 20 of 204. Sign in to see all of them.
Parkinson Disease (172) · Lewy Body Disease (12) · Dementia (10) · Parkinsonian Disorders (10) · Depression (9) · Tourette Syndrome (9) · Urinary Bladder, Overactive (7) · Cognitive Dysfunction (6) · Dyskinesias (6) · Huntington Disease (4) · Movement Disorders (4) · Parasomnias (4) · Psychotic Disorders (4) · REM Sleep Behavior Disorder (4) · Sleep Wake Disorders (4)
Brain Diseases (202) · Central Nervous System Diseases (202) · Nervous System Diseases (202) · Movement Disorders (199) · Neurodegenerative Diseases (196) · Synucleinopathies (182) · Parkinsonian Disorders (176) · Mental Disorders (55) · Pathological Conditions, Signs and Symptoms (54) · Signs and Symptoms (53) · Neurologic Manifestations (38) · Neurocognitive Disorders (25) · Behavior (17) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (16)
rasagiline (16) · Levodopa (15) · carbidopa, levodopa drug combination (10) · Pramipexole (9) · Stalevo (8) · Sugars (8) · rotigotine (8) · Amantadine (5) · Apomorphine (5) · Carbidopa (5) · Dexmedetomidine (5) · Donepezil (5) · Droxidopa (5) · Memantine (5) · Selegiline (4)
Boehringer Ingelheim (7) · Seoul National University Hospital (7) · Mayo Clinic (5) · Baylor College of Medicine (4) · Technische Universität Dresden (4) · University of South Florida (4) · Bial - Portela C S.A. (3) · GlaxoSmithKline (3) · IRCCS San Raffaele Roma (3) · Novartis (3) · Oregon Health and Science University (3) · Orion Corporation, Orion Pharma (3) · Second Affiliated Hospital of Soochow University (3) · University of Pennsylvania (3) · Amsterdam UMC, location VUmc (2)
United States (94) · Germany (20) · France (18) · South Korea (15) · Italy (14) · China (12) · Spain (12) · Austria (7) · Sweden (7) · United Kingdom (7) · Canada (6) · Slovakia (5) · Finland (4) · Netherlands (4) · Denmark (3)
William G Ondo, MD (4) · Beom S Jeon, MD, PhD (3) · Daniel Weintraub, MD (3) · Alberto Espay, MD (2) · Bradley Boeve, MD (2) · David Devos, MD, PhD (2) · Eungseok Oh (2) · Harvey S Singer, MD (2) · Jee-Young Lee, MD, PhD (2) · Jinse Park (2) · Jisun Kim (2)
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