165 completed, 60 unknown, 43 recruiting, 19 terminated. 103 Not applicable, 42 Phase 2, 27 Phase 3, 18 Phase 4, 10 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Understanding Lifespan Trajectories of Social Cognition, Brain Microstructure and Iron Dysregulation in Schizophrenia Healthy Control Subjects, Schizophrenia Diagnosis | Recruiting | Medical University Innsbruck | 180 | 2026-09-01 | 2026-10-02 | |
| Dresden MDS Registry With an Accompanying Biomaterial Collection MDS (Myelodysplastic Syndrome), MDS/Myeloproliferative Neoplasm (MPN) Overlap Syndrome | Not yet recruiting | Technische Universität Dresden | 500 | 2026-09-01 | 2026-08-27 | |
| A Trial for the Treatment of Advanced Large-Cell Neuroendocrine Cancer of the Lung Obrixtamig - Large Cell Neuroendocrine Carcinoma of the Lung | Phase 2 | Not yet recruiting | Technische Universität Dresden | 75 | 2026-09-01 | 2026-08-26 |
| Healthy Adaptation to Pregnancy, Postpartum and Parenthood HAP3 Family App - Perinatal Mental Health, Gestational Weight Gain | Not applicable | Not yet recruiting | KU Leuven | 572 | 2026-09-01 | 2026-09-23 |
| Wearable Blood-Pressure Monitoring Comparison Study Hypertension, Blood Pressure Monitoring | Recruiting | Technische Universität Dresden | 120 | 2026-07-20 | 2026-08-26 | |
| Machine Learning-based Surgical Guidance System for Robot-assisted Rectal Surgery Additional visualisation of surgical assistance during surgery - Rectum Cancer | Not applicable | Recruiting | Technische Universität Dresden | 12 | 2026-02-25 | 2026-08-27 |
| Evaluation of Treosulfan Versus Melphalan Conditioning Followed by PTCy in Patients With AML and MDS Undergoing Allogeneic Transplantation Treosulfan (Treo), Melphalan (Mel), Fludarabine (Flud) - AML - Acute Myeloid Leukemia, MDS (Myelodysplastic Syndrome) | Phase 2 | Recruiting | Technische Universität Dresden | 220 | 2026-01-21 | 2026-09-02 |
| Machine Learning for Prediction of Therapy Response in Autoimmune Hepatitis Autoimmune Hepatitis | Active not recruiting | Hannover Medical School | 5000 | 2026-01-05 | 2026-01-30 | |
| Quality of Life and Medical Care of Long-term Sarcoma Survivors in Germany (PROSa+) No intervention (observational study) - Sarcoma, Survivorship | Recruiting | Technische Universität Dresden | 1600 | 2025-11-28 | 2025-12-08 | |
| Clinical Impact Through AI-assisted MS Care - A Prospective Multi-center Study quantitative brain MRI (icobrain mr), Standard of Care (SOC) - Multiple Sclerosis, Radiologically Isolated Syndrome | Not applicable | Enrolling by invitation | icometrix | 750 | 2025-10-09 | 2025-12-09 |
| Precise Eating Time to Improve Glycemic Control and Cardiometabolic Health in Prediabetes and Diabetes Early Time-Restricted Eating, Late Time-Restricted Eating - Prediabetes, Type 2 Diabetes | Not applicable | Recruiting | German Institute of Human Nutrition | 30 | 2025-10-01 | 2026-09-29 |
| Immune-Marker Platform for Patients With Advanced Lung Cancer NSCLC (Advanced Non-small Cell Lung Cancer), NSCLC Stage IIIB~IV | Not yet recruiting | Technische Universität Dresden | 500 | 2025-09-01 | 2025-09-08 | |
| Radiation-induced Toxicity of the Heart Imaging and biomarkers - Non-small Cell Lung Cancer, Esophageal Cancer | Not applicable | Not yet recruiting | Technische Universität Dresden | 325 | 2025-08-01 | 2025-05-29 |
| Prospective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Neoplasia With IDH1 (Isocitrate Dehydrogenase 1) Mutation Ivosidenib 250 MG (milligram) - AML, MDS | Phase 2 | Recruiting | Technische Universität Dresden | 76 | 2025-06-17 | 2026-08-26 |
| Intelligent Lung Support in the Intensive Care Unit Artificial intelligence based decision support system (AI-DSS); software - Mechanical Ventilation, Intensive Care Medicine | Recruiting | Technische Universität Dresden | 530 | 2025-05-25 | 2026-07-02 | |
| Gilteritinib in Combination With Venetoclax and Azacitidine for AML Patients With FLT3 Mutations Ineligible for Intensive Treatment Gilteritinib (GILT), Venetoclax (VEN), Azacitidine (AZA) - AML - Acute Myeloid Leukemia | Phase 2 | Recruiting | Technische Universität Dresden | 60 | 2025-04-25 | 2025-05-29 |
| Pancreatic Head Resection or Total Pancreatectomy With Islet Autotransplantation in Patients With Periampullary Cancer and High Risk Profile for the Development of Postoperative Pancreatic Fistula Intraportal transplantation of isolated autologous pancreatic islets after total pancreatectomy, Pancreaticoduodenectomy (classic Whipple or pylorus-preserving) - Periampullary Cancer, Postoperative Pancreatic Fistula | Phase 3 | Recruiting | Technische Universität Dresden | 32 | 2025-01-28 | 2026-01-30 |
| Effect of Social Isolation on the Role of Pavlovian Mechanisms for Control Over Alcohol Use PIT paradigm, social exclusion (Cyberball task), Saliva samples - Alcohol Use Disorder, Alcoholism | Not applicable | Not yet recruiting | Charite University, Berlin, Germany | 100 | 2024-10-01 | 2024-08-28 |
| Role of Pavlovian Mechanisms for Control Over Substance Use fMRI imaging (BOLD), sMRI (structure), Pavlovian-to-instrumental transfer (PIT) paradigm - Alcohol Use Disorder (AUD), Alcoholism | Recruiting | Technische Universität Dresden | 200 | 2024-08-05 | 2024-11-22 | |
| Individualized Radiation Dose Prescription in HNSCC Based on F-MISO-PET Hypoxia-Imaging dose-escalated radiochemotherapy, dose-escalated radiochemotherapy with carbon ion boost, standard radiochemotherapy - Head and Neck Squamous Cell Carcinoma | Phase 2 | Not yet recruiting | Technische Universität Dresden | 276 | 2024-07-01 | 2023-09-11 |
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Leukemia, Myeloid, Acute (23) · Alcoholism (15) · Diabetes Mellitus, Type 2 (8) · Glaucoma (8) · Parkinson Disease (8) · Dermatitis, Atopic (7) · Myelodysplastic Syndromes (7) · Osteoarthritis, Knee (7) · Carcinoma, Non-Small-Cell Lung (6) · Colorectal Neoplasms (6) · Diabetes Mellitus (6) · Head and Neck Neoplasms (6) · Brain Neoplasms (5) · Esophageal Neoplasms (5) · Obesity (5)
Azacitidine (5) · Blood Specimen Collection (4) · Pharmaceutical Preparations (4) · Radiotherapy (4) · Budesonide (3) · Cetuximab (3) · Cytarabine (3) · Ethanol (3) · Photons (3) · Tacrolimus (3) · Tomography, Optical Coherence (3) · pimecrolimus (3) · venetoclax (3) · Acarbose (2) · Amoxicillin (2)
Germany (281) · Austria (9) · Italy (9) · Switzerland (8) · United Kingdom (8) · Spain (7) · United States (7) · Belgium (6) · Czechia (6) · France (5) · Netherlands (5) · Poland (5) · Israel (4) · Brazil (3) · Canada (2)
Mechthild Krause, Prof. (6) · Wilhelm Kirch, MD (6) · David Pittrow, MD, PhD (4) · Hans-Ulrich Wittchen, Prof PhD (4) · Joerg Kotzerke, MD (4) · Marius Distler, Prof. Dr. (4) · Roland Aschoff, MD (4) · Uwe Platzbecker, MD (4) · Andreas Heinz, Prof MD (3) · Gerhard Ehninger, MD (3) · Karin R Pillunat, MD (3) · Marcelo Gama de Abreu, MD, PhD (3)
PMID 36064577, PMID 24923295, PMID 28945881, PMID 36001430, PMID 17335327, PMID 17502459, PMID 18056840, PMID 18669959, PMID 18703875, PMID 19509014, PMID 19828019, PMID 19863501, PMID 19942479, PMID 20145269, PMID 20338042, PMID 20442365, PMID 21045639, PMID 21553090, PMID 21566204, PMID 21685468, PMID 21771098, PMID 21865014, PMID 22197676, PMID 22434180, PMID 22647314, PMID 22723267, PMID 22877506, PMID 22965967, PMID 22976553, PMID 23088451, PMID 23093163, PMID 23164592, PMID 23197234, PMID 23385321, PMID 23630210, PMID 23668549, PMID 23716272, PMID 23720182, PMID 23941576, PMID 24081973, PMID 24172538, PMID 24176188, PMID 24176199, PMID 24560581, PMID 24585720, PMID 24689056, PMID 24820045, PMID 24844270, PMID 24885921, PMID 25038824
2008 (2), U01AA017900 (2), 2005 (1), 2009 (1), 2014 (1), 2016 (1), 2017 (1), 2018 (1), 2023 (1), 2025 (1), R01MH122706 (1)