65 recruiting. 65 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 65 | Recruiting 65 |
Follow Arthritis: new trials by email Literature Review of Arthritis trials Research Report on Arthritis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| E-Type - Early Wear of Polyethylene Liners Used in DMC Total Hip Arthroplasty - Osteoarthritis, Osteonecrosis | Phase 4 | Recruiting | Uppsala University | 40 | 2026-10-08 | 2026-10-09 |
| Personalized Analgesia Through Central Nervous System Engagement to Unlock Performance Duloxetine, Placebo - Knee Osteoarthritis (Knee OA), Chronic Pain | Phase 4 | Recruiting | Benedict Alter | 85 | 2026-09-15 | 2026-10-21 |
| Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA bupivacaine-meloxicam (extended release), Bupivacaine, Ketorolac - Periarticular Block, Osteoarthritis (OA) | Phase 4 | Recruiting | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | 150 | 2026-09-03 | 2026-10-28 |
| A Remotely Conducted Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically Breast Milk Sample Collection, Guselkumab - Psoriasis, Colitis, Ulcerative | Phase 4 | Recruiting | Janssen Research & Development, LLC | 10 | 2026-08-07 | 2026-10-05 |
| Success Rates and Safety of Steroid Injections in Managing Spinal and Sacro-Iliac Pain (CORTisone Injection Spine Study) triamcinolone acetonide (Kenalog), Celestone Soluspan 6Mg/Ml Suspension for Injection, Depo-Medrol 40Mg/Ml Suspension for Injection - Back Pain Lower Back, Neck Pain | Phase 4 | Recruiting | Igor Wilderman. MD | 500 | 2026-07-30 | 2026-08-13 |
| Discontinuation of Disease-modifying Anti-rheumatic Drugs (DMARDs) in Rheumatoid Arthritis Patients Also Using TNF Inhibitors Strategy to attempt discontinuation of MTX or LEF (and restart when necessary), Continuation of MTX or LEF - Rheumatoid Arthritis (RA) | Phase 4 | Recruiting | Sint Maartenskliniek | 202 | 2026-07-14 | 2026-09-03 |
| SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) Trial Empagliflozin 10 mg, Placebo - Gout and Hyperuricemia | Phase 4 | Recruiting | Massachusetts General Hospital | 60 | 2026-07-01 | 2026-08-05 |
| Post-op Prednisone and Glucose Monitoring in TKA Prednisone, Continuous Glucose Monitor, InkWell Health Tattoos - Osteoarthritis, Unicompartmental Knee Arthroplasty | Phase 4 | Recruiting | Columbia University | 104 | 2026-06-22 | 2026-10-02 |
| Deucravacitinib-TNFi Combination Therapy for Difficult-to-Control Psoriatic Disease Deucravacitinib, Placebo - Psoriatic Arthritis (PsA) | Phase 4 | Recruiting | University of Texas Southwestern Medical Center | 128 | 2026-06-16 | 2026-09-01 |
| Impact of Glucagon-like Peptide-1 (GLP-1) Analogs on Disease Outcomes in Psoriatic Arthritis: A Pragmatic Randomized Controlled Trial GLP-1 agonists, Nutrition Counseling - Psoriatic Arthritis (PsA) | Phase 4 | Recruiting | Medical College of Wisconsin | 22 | 2026-05-01 | 2026-08-10 |
| Carotid Ultrasound-Based Strategy for Primary Prevention of Cardiovascular Events in Inflammatory Rheumatic Disease (PREVENER) Carotid Ultrasound, High-intensity lipid-lowering therapy, Standard care according to ESC 2021 guidelines - Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA) | Phase 4 | Recruiting | Instituto de Investigación Marqués de Valdecilla | 1944 | 2026-04-22 | 2026-05-28 |
| Oral Versus Intramuscular Steroid Use to Control Rheumatoid Arthritis Flares Glucocorticoid (GC) - Rheumatoid Arthritis (RA) | Phase 4 | Recruiting | Sunnybrook Health Sciences Centre | 220 | 2026-04-01 | 2026-04-13 |
| Preventing Structural Damage in Early Psoriatic Arthritis Amgevita 40Mg Solution for Injection, Methotrexate (Metoject® prefilled pen) - Psoriatic Arthritis (PsA) | Phase 4 | Recruiting | Chinese University of Hong Kong | 108 | 2026-03-16 | 2026-03-23 |
| Safety and Immunogenicity of the Live Attenuated Tetravalent Butantan-Dengue Vaccine in Autoimmune Rheumatic Diseases Dengue 1,2,3,4 (attenuated) vaccine - Rheumatoid Arthritis (RA), Juvenile Idiopathic Arthritis (JIA) | Phase 4 | Recruiting | University of Sao Paulo General Hospital | 477 | 2026-03-16 | 2026-07-20 |
| TREATMENT OF VAGINAL DRYNESS IN SJÖGREN'S DISEASE WITH CO2-LASER VERSUS TOPICAL PROMESTRIENE Fractional CO2 laser (vaginal), Promestriene Vaginal - Sjogren Syndrome, Sjogren Disease | Phase 4 | Recruiting | University of Sao Paulo General Hospital | 60 | 2026-02-27 | 2026-03-03 |
| Arthrosamid vs. Steroid for the Management of Knee Osteoarthritis Arthrosamid® 2.5% iPAAG injectable implant, Steroid Drug - Osteo Arthritis Knee, Osteoarthritis | Phase 4 | Recruiting | Cappagh National Orthopaedic Hospital | 200 | 2026-01-29 | 2026-04-28 |
| Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout Flares Purified Cortophin Gel, 40 U, Purified Cortophin Gel 80 U - Gout Arthritis, Gout Flare | Phase 4 | Recruiting | Massachusetts General Hospital | 150 | 2025-12-20 | 2026-01-20 |
| Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate to Severe Disease Activity Treated With Tofacitinib and Statins vs TNF Inhibitors: TOFSTAT CLINICAL TRIAL Tofacitinib 5 MG - Rheumatoid Arthritis, Major Adverse Cardiac Events | Phase 4 | Recruiting | Shaikh Zayed Hospital, Lahore | 120 | 2025-12-06 | 2026-04-28 |
| Integrated Clinical Study of Traditional Chinese and Western Medicine for Refractory Rheumatoid Arthritis Kunxian Capsule, Kunxian Capsule Placebo - Rheumatoid Arthritis (RA) | Phase 4 | Recruiting | Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine | 300 | 2025-10-15 | 2026-07-22 |
| PENG vs L-ESPB With S-ESPB for Analgesia in Total Hip Arthroplasty Ropivacaine 0.5% Injectable Solution, Ropivacaine 0.2% Injectable Solution - Hip Osteoarthritis, Hip Arthropathy | Phase 4 | Recruiting | Poznan University of Medical Sciences | 90 | 2025-09-15 | 2026-05-07 |
Showing 20 of 65. Sign in to see all of them.
Arthritis, Rheumatoid (19) · Osteoarthritis (12) · Arthritis, Psoriatic (10) · Osteoarthritis, Knee (8) · Gout (6) · Axial Spondyloarthritis (4) · Osteoarthritis, Hip (4) · Pain, Postoperative (4) · Hyperuricemia (3) · Sjogren's Syndrome (3) · Arthritis, Infectious (2) · Arthritis, Juvenile (2) · Chronic Pain (2) · Lupus Erythematosus, Systemic (2) · Osteomyelitis (2)
Musculoskeletal Diseases (65) · Joint Diseases (64) · Rheumatic Diseases (52) · Skin and Connective Tissue Diseases (31) · Connective Tissue Diseases (24) · Autoimmune Diseases (23) · Immune System Diseases (23) · Bone Diseases (17) · Pathological Conditions, Signs and Symptoms (15) · Spinal Diseases (14) · Spondylitis (14) · Spondylarthritis (13) · Spondylarthropathies (13) · Pathologic Processes (12)
Methotrexate (6) · tofacitinib (4) · Duloxetine Hydrochloride (3) · Etanercept (3) · Prednisone (3) · Rituximab (3) · Adalimumab (2) · Dexamethasone (2) · Febuxostat (2) · GLPG0634 (2) · Hydroxychloroquine (2) · Injections (2) · Leflunomide (2) · Pharmaceutical Preparations (2) · Sodium Chloride (2)
Massachusetts General Hospital (3) · Chinese University of Hong Kong (2) · Henry Ford Health System (2) · LifeBridge Health (2) · Sint Maartenskliniek (2) · Sunnybrook Health Sciences Centre (2) · University Hospital, Strasbourg, France (2) · University of Sao Paulo General Hospital (2) · Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) (1) · Benedict Alter (1) · CARE ARTHRITIS LTD. (1) · Cappagh National Orthopaedic Hospital (1) · Centre Hospitalier Universitaire de Saint Etienne (1) · Charite University, Berlin, Germany (1) · China-Japan Friendship Hospital (1)
United States (22) · China (8) · Canada (6) · France (5) · Netherlands (3) · Brazil (2) · Hong Kong (2) · Ireland (2) · Japan (2) · Norway (2) · Taiwan (2) · Australia (1) · Austria (1) · Belgium (1) · Germany (1)
Hyon K Choi, MD, DrPH (2) · Aflak Rasheed, FCPS (1) · Amanda Gwee, PhD (1) · Amanda L Dempsey (1) · Andrew Waligora, MD (1) · Anna-Birgitte Aga, MD PhD (1) · Benedict Alter, MD, PhD (1) · Brent Becker, MD (1) · Denis Poddubbnyy, Prof. Dr. med. (1) · Frederic T Billings, IV, MD (1)
PMID 36855169, PMID 39407334, PMID 39669005, PMID 40078463, PMID 41423293, PMID 41703606, PMID 42148589
2023 (2), 2025 (2), K23NS123429 (1), R01AG085287 (1), R61AR084188 (1), U01AR080985 (1)