209 completed, 41 unknown, 32 recruiting, 14 terminated. 77 Phase 2, 62 Not applicable, 59 Phase 1, 50 Phase 3, 31 Phase 4.
Follow this condition Literature Review of Gout trials Research Report on Gout
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacist-Led Treat-to-Target Urate Lowering Therapy in Patients With Gout Pharmacist-Led - Gout, Gouty Arthritis | Not applicable | Recruiting | VA Office of Research and Development | 310 | 2026-10-01 | 2026-10-21 |
| Mazdutide for Weight Management and Gout in Adults With Obesity Mazdutide - Gout, Obesity (BMI>30) | Phase 4 | Not yet recruiting | Hongwei Jiang | 30 | 2026-09-15 | 2026-09-17 |
| The Correlation Between Sodium Urate (MSU) Deposition and Coronary Atherosclerosis in Patients With Foot Gout DECT;CCTA - Gout, Coronary Atheroma | Not yet recruiting | The Affiliated Hospital of Qingdao University | 200 | 2026-08-20 | 2026-08-25 | |
| A Study of SSGJ-613 in Gout Participants Initiating Urate-Lowering Treatment SSGJ-613 100 mg Q12W, SSGJ-613 200 mg Q12W, SSGJ-613 100 mg Q4W - Gout Arthritis | Phase 2 | Not yet recruiting | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 200 | 2026-08-02 | 2026-07-20 |
| The Impact of Initiating Dotinurad Urate-Lowering Therapy at Different Time Windows on Gout Flare Resolution Time Dotinurad, colchicine, etoricoxib - Gout | Phase 4 | Not yet recruiting | First Affiliated Hospital of Wenzhou Medical University | 142 | 2026-07-30 | 2026-06-22 |
| SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) Trial Empagliflozin 10 mg, Placebo - Gout and Hyperuricemia | Phase 4 | Recruiting | Massachusetts General Hospital | 60 | 2026-07-01 | 2026-08-05 |
| Musculoskeletal Ultrasound for Differentiating Rheumatoid and Gouty Arthritis Rheumatoid Arthritis (RA), Gouty Arthritis (GA) | Not yet recruiting | Assiut University | 100 | 2026-07-01 | 2026-06-18 | |
| A Study of IN026 in Participants With Refractory Gout IN026 Injection - Refractory Gout | Phase 1 | Recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 16 | 2026-06-12 | 2026-07-31 |
| Digital Care for Holistic Health in Older Adults With Diabetes and Multimorbidity Digital Care Community Common Good Program, Usual Care - Type2Diabetes, Hypertension | Not applicable | Recruiting | Chang Gung University of Science and Technology | 169 | 2026-05-12 | 2026-08-21 |
| A Phase 2 Trial of Dotinurad in Xanthine Oxidase Inhibitor (XOI) Intolerant/Uricase Failure Gout Participants Dotinurad, Placebo - Gout | Phase 2 | Recruiting | Crystalys Therapeutics | 90 | 2026-05-08 | 2026-09-28 |
| Probiotic-Uricase Complex Preparation for Improving Uric Acid Metabolism in Patients With Hyperuricemia Probiotic-uricase complex preparation - Hyperuricemia, Gout | Not applicable | Not yet recruiting | Maanshan Shiqiye Hospital | 45 | 2026-05-01 | 2026-05-29 |
| Acute Effects of a Urate-lowering Bacterial Therapeutic on Small Intestinal Transcriptomics and Glycomics in Healthy Subjects BEO001 Probiotic, BEO001 Probiotic + Beta-Glucan, Placebo - Healthy, Hyperuricemia, Gout | Not applicable | Active not recruiting | Örebro University, Sweden | 8 | 2026-04-09 | 2026-10-20 |
| Clinical Trial of BR2251 Tablets for Patients With Primary Gout and Hyperuricemia BR2251, Febuxostat - Gout and Hyperuricemia | Phase 2 | Not yet recruiting | BioRay Pharmaceutical Co., Ltd. | 160 | 2026-04-01 | 2026-03-27 |
| The Remote Monitoring of Gout Feasibility Study in Primary Care Patient self-management app 'MinUrinsyregikt' - Gout | Not applicable | Recruiting | Diakonhjemmet Hospital | 50 | 2026-04-01 | 2026-04-30 |
| Tigulixostat (IBI128) vs Febuxostat in Gout Febuxostat, Tigulixostat - Gout | Phase 3 | Active not recruiting | Innovent Biologics Technology Limited (Shanghai R&D Center) | 600 | 2026-03-17 | 2026-09-01 |
| Drug-Drug Interaction Study of ABP-671 in Gout Patients ABP-671 plus allopurinol - Gout Chronic, Gout | Phase 1 | Recruiting | Atom Therapeutics Co., Ltd | 20 | 2026-01-23 | 2026-04-14 |
| HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-Effectiveness HLA-B*58:01 Genotyping, Allopurinol Tablet, Febuxostat - Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis | Phase 4 | Not yet recruiting | Haiphong University of Medicine and Pharmacy | 228 | 2026-01-20 | 2026-01-27 |
| An Exploratory Clinical Study on the Protective Effect of Cycling on the Ankle Joint in Gout Urate-lowering therapy (ULT), Jogging, Cycling - Gout Arthritis, Cycling | Not applicable | Not yet recruiting | Zhu Xiaoxia | 90 | 2026-01-01 | 2025-12-31 |
| A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE) PRX-115, Methotrexate (MTX), PRX-115 placebo - Gout | Phase 2 | Recruiting | Protalix | 150 | 2025-12-22 | 2026-09-29 |
| Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout Flares Purified Cortophin Gel, 40 U, Purified Cortophin Gel 80 U - Gout Arthritis, Gout Flare | Phase 4 | Recruiting | Massachusetts General Hospital | 150 | 2025-12-20 | 2026-01-20 |
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Hyperuricemia (98) · Arthritis, Gouty (42) · Arthritis (26) · Arthritis, Rheumatoid (19) · Cardiovascular Diseases (17) · Diabetes Mellitus (17) · Osteoarthritis (16) · Hypertension (15) · Obesity (12) · Renal Insufficiency, Chronic (12) · Rheumatic Diseases (11) · Dyslipidemias (10) · Joint Diseases (8) · Metabolic Syndrome (8)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (332) · Nutritional and Metabolic Diseases (332) · Crystal Arthropathies (331) · Genetic Diseases, Inborn (328) · Metabolism, Inborn Errors (328) · Purine-Pyrimidine Metabolism, Inborn Errors (328) · Metabolic Diseases (327) · Musculoskeletal Diseases (327) · Joint Diseases (324) · Rheumatic Diseases (321) · Arthritis (306) · Pathological Conditions, Signs and Symptoms (132) · Pathologic Processes (116) · Skin and Connective Tissue Diseases (33) · Connective Tissue Diseases (29)
Febuxostat (46) · Allopurinol (45) · Colchicine (29) · Pegloticase (12) · lesinurad (12) · verinurad (11) · canakinumab (10) · Methotrexate (8) · Naproxen (7) · Triamcinolone Acetonide (7) · ruzinurad (7) · dotinurad (6) · rilonacept (6) · arhalofenate (5) · Etoricoxib (4)
Ardea Biosciences, Inc. (20) · Takeda (15) · LG Chem (10) · Novartis Pharmaceuticals (10) · Atom Therapeutics Co., Ltd (9) · Regeneron Pharmaceuticals (7) · Amgen (6) · Arthrosi Therapeutics (6) · Assistance Publique - Hôpitaux de Paris (6) · AstraZeneca (6) · Jiangsu HengRui Medicine Co., Ltd. (6) · Lille Catholic University (6) · Allena Pharmaceuticals (5) · Gilead Sciences (5) · University of Alabama at Birmingham (5)
United States (159) · China (39) · Canada (26) · France (19) · Taiwan (19) · Australia (18) · Germany (18) · United Kingdom (16) · Poland (13) · New Zealand (12) · Belgium (11) · South Korea (10) · Russia (9) · South Africa (9) · Spain (9)
J. Hall, MD (5) · Chris Storgard, MD (4) · Nihar Bhakta, MD (4) · David JA Jenkins, MD, PhD, DSc (3) · Hyungjin Cho, MD (3) · John L Sievenpiper, MD, PhD (3) · Robert Evans, PharmD (3) · Robert Keenan, MD (3) · Alan Hollister, MD, PhD (2) · Anthony S Fiorino, MD, PhD (2) · C Tosone, MS, RAC (2)
PMID 35835008, PMID 21353107, PMID 22052584, PMID 24122883, PMID 16911575, PMID 18600509, PMID 22172492, PMID 24286509, PMID 24588936, PMID 31203212, PMID 32951150, PMID 33399399, PMID 34882311, PMID 35022448, PMID 37746085, PMID 38485432, PMID 39929260, PMID 12535399, PMID 12867348, PMID 15751090, PMID 16331766, PMID 16339094, PMID 16439323, PMID 16620352, PMID 17053334, PMID 18759308, PMID 18975369, PMID 19141576, PMID 19286847, PMID 20131255, PMID 20370912, PMID 20533546, PMID 20660758, PMID 21169856, PMID 21272692, PMID 21295195, PMID 21372003, PMID 21439048, PMID 21540198, PMID 21572152, PMID 21846852, PMID 21849262, PMID 22132950, PMID 22223180, PMID 22316106, PMID 22331380, PMID 22351714, PMID 22354959, PMID 22358823, PMID 22436129
1UL1TR001114-01 (1), 2008 (1), 2009 (1), 2014 (1), 2015 (1), 2025 (1), I01CX002995 (1), P30AG064199 (1), P50AR060772 (1), R21DK105401 (1), R21DK132666 (1), R61AR084188 (1), U01AR080985 (1), U48DP006398 (1), U48DP006850 (1)