16 completed, 4 unknown, 2 recruiting, 1 not yet recruiting. 25 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 25 | Completed 16, Unknown 4, Recruiting 2, Not yet recruiting 1, Terminated 1, Withdrawn 1 |
Follow Ankle Injuries: new trials by email Literature Review of Ankle Injuries trials Research Report on Ankle Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery Buprenorphine Transdermal System, Placebo Patch - Pain, Postoperative, Ankle Fracture Surgery | Phase 4 | Recruiting | Jenna-Leigh Wilson | 100 | 2025-04-21 | 2026-04-06 |
| Compression Therapy for Swelling Management Following Ankle Injury Compression sleeve - Ankle Fracture, Ankle Arthrodesis | Phase 4 | Not yet recruiting | Nova Scotia Health Authority | 50 | 2025-04-01 | 2025-01-24 |
| Dexmedetomidine Vs Dexamethasone in Popliteal Nerve Block 0.9% Sodium chloride, 0.1mg/kg Dexamethasone, 0.05ug/kg Dexmedetomidine - Ankle Disease, Ankle Injuries and Disorders | Phase 4 | Unknown | Poznan University of Medical Sciences | 90 | 2024-05-06 | 2025-01-21 |
| Dexamethasone vs. Dexmedetomidine for Popliteal Nerve Block in Pain Management After Pediatric Ankle and Foot Surgery 0.9%sodium chloride, Dexamethasone, Dexmedetomidine - Foot Injuries and Disorders, Ankle Injuries and Disorders | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2024-02-09 | 2025-07-11 |
| Approach to Ankle Sprains in the Emergency Department Dexketoprofen Trometamol 50 Mg/mL Solution for Injection, Ibuprofen 100 MG/ML Solution for Injection, Paracetamol 10 Mg/mL Solution for Injection - Ankle Sprains | Phase 4 | Completed | Ankara Etlik City Hospital | 150 | 2023-12-01 | 2024-08-20 |
| Perineural Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery 0.9 % Sodium Chloride, 0.1mg/kg Dexamethasone, 0.05mg/kg Dexamethasone - Ankle Disease, Ankle Injuries | Phase 4 | Completed | Poznan University of Medical Sciences | 90 | 2023-10-17 | 2025-01-21 |
| Rebound Pain Following Regional Anaesthesia for Ankle Fracture Surgery continuous infusion of levobupivacaine, oxycodone - Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Ankle Fracture - Lateral Malleolus | Phase 4 | Completed | University College Cork | 120 | 2023-10-16 | 2026-08-19 |
| Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery Exparel, Peripheral Nerve Block - Pain, Postoperative, Pain, Acute Postoperative | Phase 4 | Completed | St. Luke's Hospital, Pennsylvania | 248 | 2022-03-01 | 2026-04-28 |
| CBD for Pain Reduction and Opioid Use After Ankle and Tibia Fracture ORIF CBD, Placebo - Ankle Fractures, Tibia Fracture | Phase 4 | Withdrawn | NYU Langone Health | 2021-10-01 | 2022-01-28 | |
| Randomized Controlled Trial for Ankle Fracture Pain Control Long-Acting Local Anesthesia, Regional Anesthesia - Ankle Fractures | Phase 4 | Recruiting | Lahey Clinic | 70 | 2020-09-01 | 2026-10-08 |
| The Effect of Proprioception of Platelet Rich Plasma for Patients With Ankle Sprain PRP, Rehabilitation, PRP+Rehabilitation - Ankle Sprain 2Nd Degree, Ankle Sprain 3Rd Degree | Phase 4 | Unknown | National Defense Medical Center, Taiwan | 60 | 2019-10-01 | 2023-10-02 |
| Comparing Function, Pain and Return to Work in Conservative Versus Surgical Treated Stable Lateral Malleolar Fractures Surgical intervention - Malleolus Fracture, Lateral | Phase 4 | Terminated | Insel Gruppe AG, University Hospital Bern | 3 | 2018-05-01 | 2023-03-08 |
| Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures Ropivacaine, Epinephrine, Morphine - Pain, Postoperative, Ankle Fractures | Phase 4 | Completed | University of Iowa | 100 | 2016-10-01 | 2023-12-15 |
| Ankle Fractures Treated With Teriparatide Forsteo - Fracture, Ankle | Phase 4 | Unknown | Nottingham University Hospitals NHS Trust | 10 | 2016-10-01 | 2016-11-04 |
| Effect of Toradol on Post-operative Foot and Ankle Healing Ketorolac, No ketorolac - Ankle Fractures, Trauma Injury | Phase 4 | Completed | Rothman Institute Orthopaedics | 128 | 2016-08-01 | 2018-11-01 |
| Ketoprofen Gel vs Placebo in Children With Ankle Sprain Ketoprofen, Placebo - Ankle Sprain | Phase 4 | Unknown | Akdeniz University | 100 | 2015-06-01 | 2015-12-03 |
| Topical Ketoprofen Versus Placebo in Patients With Ankle Sprain Ketoprofen gel, Placebo - Ankle Sprain | Phase 4 | Completed | Akdeniz University | 100 | 2015-02-01 | 2015-07-07 |
| Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication Patient Information Leaflet (PIL) - Ankle Sprain, Infectious Colitis | Phase 4 | Completed | Floralis | 211 | 2014-09-01 | 2015-08-27 |
| Efficacy of Topical Indomethacin Patch Over Placebo in Ankle Sprain Pain Relief Indomethacin, Placebo - Ankle Sprain | Phase 4 | Completed | GlaxoSmithKline | 270 | 2013-10-01 | 2015-06-15 |
| Efficacy and Safety of Diclofenac Potassium 25 mg Tablet Taken Three Times Daily in Subjects With Acute Joint Pain diclofenac potassium 25 mg tablet, placebo - Ankle Sprain | Phase 4 | Completed | Novartis | 100 | 2012-08-01 | 2014-04-17 |
Showing 20 of 25. Sign in to see all of them.
Ankle Fractures (12) · Disease (3) · Foot Injuries (3) · Pain, Postoperative (3) · Foot Diseases (2) · Accidental Injuries (1) · Acute Pain (1) · Agnosia (1) · Diverticulitis (1) · Emergencies (1) · Opioid-Related Disorders (1) · Pain (1) · Personal Satisfaction (1) · Pneumonia (1)
Leg Injuries (25) · Wounds and Injuries (25) · Fractures, Bone (12) · Pathological Conditions, Signs and Symptoms (9) · Neurologic Manifestations (6) · Pathologic Processes (6) · Signs and Symptoms (6) · Pain (4) · Postoperative Complications (3) · Musculoskeletal Diseases (2) · Skin Diseases (2) · Skin and Connective Tissue Diseases (2) · Behavior (1) · Chemically-Induced Disorders (1)
Sodium Chloride (6) · Dexamethasone (4) · Acetaminophen (2) · Calcium Dobesilate (2) · Dexmedetomidine (2) · Anesthesia, Conduction (1) · Bupivacaine (1) · Celecoxib (1) · Diclofenac (1) · Epinephrine (1) · Ibuprofen (1) · Indomethacin (1) · Injections (1) · Ketoprofen (1) · Ketorolac (1)
Poznan University of Medical Sciences (3) · Akdeniz University (2) · Ankara Etlik City Hospital (1) · Floralis (1) · GlaxoSmithKline (1) · Hisamitsu Pharmaceutical Co., Inc. (1) · Insel Gruppe AG, University Hospital Bern (1) · Jenna-Leigh Wilson (1) · Johnson & Johnson Consumer and Personal Products Worldwide (1) · Lahey Clinic (1) · NYU Langone Health (1) · National Defense Medical Center, Taiwan (1) · National Police Hospital (1) · Northwestern University (1) · Nottingham University Hospitals NHS Trust (1)
United States (7) · Poland (3) · Turkey (Türkiye) (3) · Brazil (1) · Canada (1) · China (1) · Costa Rica (1) · Ecuador (1) · Egypt (1) · France (1) · Germany (1) · Ireland (1) · Jordan (1) · Mexico (1) · Panama (1)
Mustafa Serinken, MD (2) · Ahmet B. Erdem (1) · Angus Wallace (1) · Anna Ng-Pellegrino (1) · Brian D O'Donnell, MBBChBAO MSc FCARCSI MD (1) · Eric Swart, MD (1) · Fabian Krause, PD Dr. (1) · Jenna Wilson, MD (1) · Jung Ho Noh, M.D., Ph.D. (1) · Kyle Hancock, MD (1) · Melanie Sustersic, MD (1) · Philipp Leucht, MD (1)
PMID 17052565, PMID 30787085, PMID 32797734, PMID 39209730, PMID 40916868, PMID 41043950
2015 (1), 2017 (1)