Foot Diseases: Clinical Trials

333 completed, 84 unknown, 68 recruiting, 34 not yet recruiting. 327 Not applicable, 67 Phase 2, 46 Phase 3, 39 Phase 4, 30 Phase 1.

By phase and status

Phase	Trials	Status
Not applicable	327	Completed 183, Unknown 50, Recruiting 43, Not yet recruiting 23, Terminated 10, Withdrawn 8, Active not recruiting 5, Enrolling by invitation 5
Phase 2	67	Completed 38, Unknown 11, Terminated 8, Not yet recruiting 4, Recruiting 4, Withdrawn 2
Phase 3	46	Completed 31, Terminated 5, Unknown 5, Recruiting 2, Withdrawn 2, Active not recruiting 1
Phase 4	39	Completed 21, Unknown 6, Recruiting 5, Terminated 3, Withdrawn 3, Not yet recruiting 1
Phase 1	30	Completed 20, Terminated 4, Recruiting 3, Active not recruiting 1, Unknown 1, Withdrawn 1
Early Phase 1	3	Completed 3

Follow Foot Diseases: new trials by email Literature Review of Foot Diseases trials Research Report on Foot Diseases

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Clinical Performance of ComBatic™ Antimicrobial Wound Care Products in Hard-to-Heal Wounds Irrigation Solution for wounds, Hydrogel for wound care - Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer), Chronic Wound Care	Phase 2	Not yet recruiting	University of Calgary	96	2027-01-01	2026-10-14
Multimodal Conservative Intervention Versus Surgery for Chronic Refractory Plantar Fasciopathy Multimodal Conservative Intervention, Endoscopic Plantar Fascial Release - Chronic Refractory Plantar Fasciopathy	Not applicable	Not yet recruiting	Universidad Europea de Valencia	120	2026-12-01	2026-06-17
Radial vs Focused Shockwave Therapy for Plantar Fasciitis Focused Shockwave therapy, Radial shockwave therapy - Plantar Fasciitis, Chronic	Not applicable	Not yet recruiting	Homerton University Hospital NHS Foundation Trust	216	2026-11-01	2026-10-29
NAC-REPAIR for Post-surgical Pain NAC, NAC 0mg/day (Placebo) - Carpal Tunnel Surgery, Trigger Finger Disorder	Phase 2	Not yet recruiting	University of Arizona	80	2026-10-15	2026-07-17
In Vitro Susceptibility of Dermatophytes to Terbinafine and Itraconazole: MIC Distributions and Elevated-MIC Isolates in Faisalabad, Pakistan In vitro antifungal susceptibility testing - Dermatophytosis, Tinea Corporis		Recruiting	Dr. Amara Safdar	120	2026-10-02	2026-10-27
Baxter's Nerve Pulsed Radiofrequency Versus Platelet-Rich Plasma Injection or Both Together as a Treatment Modality of Recalcitrant Plantar Fasciitis Baxter's Nerve Pulsed Radiofrequency, Autologous Platelet-Rich Plasma Injection - Plantar Fasciitis, Heel Pain	Not applicable	Not yet recruiting	Assiut University	75	2026-10-01	2026-09-17
Nutritional Status in Adults With Diabetic Foot Ulcers Protein supplementation and nutrition education - Diabetic Foot Ulcers (DFU), Nutrition Assessment		Not yet recruiting	Hvidovre University Hospital	30	2026-09-21	2026-09-18
Tibial Nerve Size and Clinical Features in Chronic Plantar Fasciitis Pressure Pain Threshold Assessment, Plantar fascia ultrasonographic Assessment, Tibial nerve ultrasonographic assessment - Plantar Fasciitis, Chronic, Tibial Nerve		Recruiting	Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey	102	2026-09-07	2026-10-16
A Double-Blinded Study on Rapid and Sustained Pain Relief Topical Cannabidiol for Plantar Fasciitis transdermal CBD cream (Tolcylen®, Marlinz Pharma), Matched Placebos - Plantar Fasciitis	Phase 2	Not yet recruiting	University of Florida	50	2026-09-01	2026-09-03
Performance and Safety of Mepilex® Up in Leg and Foot Ulcers and Skin Tears Mepilex® Up - Leg Ulcer, Pressure Ulcer (PU)	Not applicable	Not yet recruiting	Molnlycke Health Care AB	70	2026-08-31	2026-08-26
Serum CTGF in Chronic Plantar Fasciitis Plantar Fasciitis		Not yet recruiting	Kanuni Sultan Suleyman Training and Research Hospital	60	2026-08-30	2026-08-25
Extracorporeal Shock Wave Therapy With or Without Kinesiotaping for Plantar Fasciitis Kinesio Taping, Extracorporeal Shock Wave Therapy (ESWT) - Plantar Fasciitis	Not applicable	Recruiting	Ankara City Hospital Bilkent	48	2026-08-27	2026-10-08
Evaluation of Spinal Posture, Balance, and Core Muscle Endurance in Individuals With Plantar Fasciitis evaluation - Plantar Fasciitis of Both Feet		Active not recruiting	Ahi Evran University Education and Research Hospital	64	2026-08-05	2026-08-12
Blood Flow Restriction Training in Women With Posterior Tibial Tendon Dysfunction Blood Flow Restriction Training, Conventional Physical Therapy Program - Posterior Tibial Tendon Dysfunction	Not applicable	Not yet recruiting	May University in Cairo	54	2026-08-01	2026-08-06
Outcomes of the Proprioception and Strengthening Exercise Program in Chronic Plantar Fasciitis Stretching, Proprioception and Stretching Exercises, Knee Strengthening and Stretching Exercises - Plantar Fasciitis, Chronic	Not applicable	Recruiting	Karamanoğlu Mehmetbey University	105	2026-08-01	2026-08-20
Effects of Foot-Core Strengthening and Sensorimotor Re-training With Routine Physical Therapy on Pain, Function, and Plantar Pressure in Patients With Plantar Fasciitis. Foot Core Strengthening with Routine Physical Therapy, Sensorimotor Re-training with Routine Physical Therapy - Plantar Fasciitis	Not applicable	Not yet recruiting	Lahore University of Biological and Applied Sciences	52	2026-07-28	2026-07-14
A Phase 1b Study of ZYG24004 in Participants With Tinea Pedis Caused by Dermatophytes ZYG24004 1% topical film-forming formulation, ZYG24004 3% topical film-forming formulation, Placebo topical formulation - Tinea Pedis	Phase 1	Recruiting	Sinomune Pharmaceutical Co., Ltd	64	2026-07-21	2026-08-04
Comparative Effectiveness of Different Neural Mobilization Techniques in Plantar Fasciitis nerve mobilization, physical therapy, saphenous nerve mobilization - Plantar Fasciitis, Chronic	Not applicable	Not yet recruiting	Prince Sattam Bin Abdulaziz University	60	2026-07-01	2026-06-18
Modified Platform Trial Assessing Multiple Umbilical Cord-based CAMPs and SOC v SOC Alone in the Treatment of Hard-to-Heal DFUs Standard of Care (SOC), Corplex P, Theracor - Diabetic Foot Ulcer (DFU), Ulcer Foot	Not applicable	Not yet recruiting	StimLabs	272	2026-07-01	2026-03-04
ESWT in the Treatment of Plantar Fasciitis Exercise group, 3 ESWT sessions, 5 ESWT sessions - Plantar Fasciitis, Extracorporeal Shock Wave Therapy	Not applicable	Not yet recruiting	Kirsehir Ahi Evran Universitesi	57	2026-07-01	2026-06-04

Showing 20 of 580. Sign in to see all of them.

Narrower conditions

Fasciitis, Plantar (217)  ·  Foot Ulcer (172)  ·  Diabetic Foot (113)  ·  Diabetes Mellitus (86)  ·  Tinea Pedis (70)  ·  Heel Spur (31)  ·  Leg Ulcer (27)  ·  Morton Neuroma (25)  ·  Pain (23)  ·  Metatarsalgia (22)  ·  Ulcer (21)  ·  Diabetes Complications (17)  ·  Diabetic Neuropathies (15)  ·  Foot Dermatoses (15)

Broader conditions

Musculoskeletal Diseases (334)  ·  Skin and Connective Tissue Diseases (299)  ·  Skin Diseases (293)  ·  Fasciitis (212)  ·  Pathological Conditions, Signs and Symptoms (179)  ·  Skin Ulcer (168)  ·  Leg Ulcer (148)  ·  Endocrine System Diseases (144)  ·  Signs and Symptoms (144)  ·  Cardiovascular Diseases (121)  ·  Vascular Diseases (120)  ·  Diabetic Angiopathies (108)  ·  Diabetic Neuropathies (100)  ·  Diabetes Complications (98)

Interventions

Extracorporeal Shockwave Therapy (23)  ·  Standard of Care (14)  ·  Foot Orthoses (12)  ·  Sodium Chloride (12)  ·  Adrenal Cortex Hormones (9)  ·  Exercise (8)  ·  naftifine (8)  ·  Myofascial Release Therapy (7)  ·  Terbinafine (7)  ·  Dexamethasone (6)  ·  Dry Needling (6)  ·  Muscle Stretching Exercises (6)  ·  Physical Therapy Modalities (6)  ·  Saline Solution (6)  ·  Botulinum Toxins, Type A (5)

Sponsors

Mahidol University (9)  ·  Cairo University (8)  ·  MiMedx Group, Inc. (8)  ·  Sun Pharmaceutical Industries, Inc. (8)  ·  University of Seville (8)  ·  Riphah International University (7)  ·  Chinese University of Hong Kong (6)  ·  Mayuben Private Clinic (5)  ·  National Taiwan University Hospital (5)  ·  Pfizer (5)  ·  Ankara City Hospital Bilkent (4)  ·  Endo USA Inc., a Keenova Therapeutics Company (4)  ·  Galderma R&D (4)  ·  Integra LifeSciences Corporation (4)  ·  Merz North America, Inc. (4)

Countries

United States (176)  ·  Turkey (Türkiye) (64)  ·  Spain (43)  ·  Pakistan (23)  ·  Canada (18)  ·  United Kingdom (17)  ·  Denmark (16)  ·  Egypt (16)  ·  Brazil (14)  ·  France (14)  ·  Germany (14)  ·  Poland (13)  ·  Taiwan (12)  ·  Italy (11)  ·  China (9)

Top investigators

David Armstrong, DPM, MD, PhD (4)  ·  Chandan K Sen, PhD (3)  ·  Thomas Serena, MD (3)  ·  Anya Loncaric (2)  ·  Babak Baravarian, DPM (2)  ·  Charles M Zelen, DPM (2)  ·  Charles M. Zelen, DPM (2)  ·  Daniel Piacquadio, MD (2)  ·  David Armstrong, DPM, MD PhD (2)  ·  Gilberto De Nucci, PhD (2)  ·  John Fryer, Ph.D. Asst. Director (2)  ·  Lawrence Parish, MD (2)  ·  Malene RB Larsen, MD (2)

Results publications

PMID 19935134, PMID 22882561, PMID 26982791, PMID 28924971, PMID 29951993, PMID 30415588, PMID 15606827, PMID 24299257, PMID 24703267, PMID 26437161, PMID 29782305, PMID 30515854, PMID 33785535, PMID 7425659, PMID 8852468, PMID 10534247, PMID 11124735, PMID 11491194, PMID 11991474, PMID 12146772, PMID 12879710, PMID 15152061, PMID 15576744, PMID 15811212, PMID 16045848, PMID 16182419, PMID 16556754, PMID 16558144, PMID 16842719, PMID 16882901, PMID 17076732, PMID 17161752, PMID 17400020, PMID 17456546, PMID 17515235, PMID 17761319, PMID 18348838, PMID 18822153, PMID 19386127, PMID 19601786, PMID 19841862, PMID 19857819, PMID 20067715, PMID 20091508, PMID 2037861, PMID 20398269, PMID 20427683, PMID 20460065, PMID 20691370, PMID 20798179

NIH funding

2004 (1), 2008 (1), 2009 (1), 2015 (1), 2016 (1), 2023 (1), K23DK131261 (1), P30DK020572 (1), P30DK111022 (1), R01AG071646 (1), R01DK125835 (1), R01EB028978 (1), R01HD036802 (1), R15AR054507 (1), R15AR061737 (1)