413 completed, 152 unknown, 58 recruiting, 24 not yet recruiting. 393 Not applicable, 107 Phase 4, 51 Phase 3, 42 Phase 2, 17 Phase 1.
Follow Analgesia: new trials by email Literature Review of Analgesia trials Research Report on Analgesia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia Bupivacaine-Neostigmine, Bupivacaine - Analgesia | Not applicable | Not yet recruiting | Mansoura University | 58 | 2027-12-01 | 2026-02-17 |
| Real-time Ultrasound Guidance for Thoracic Epidural Blocks Real-time ultrasound guidance for thoracic epidural catheter placement. - Analgesia, Thoracic Tumors | Withdrawn | University of Chile | 2027-07-01 | 2026-05-19 | ||
| Safety of F14 Following Total Knee Replacement F14 (sustained release celecoxib) - Analgesia | Phase 2 / Phase 3 | Suspended | Arthritis Innovation Corporation | 100 | 2027-01-01 | 2026-06-05 |
| Evaluation of Consciousness Depth (qCON) and Analgesia Depth (qNOX) Indices in General Anesthesia Cesarean Section (MeSH: D002585), Anesthesia | Not yet recruiting | Kudret Dogru | 140 | 2026-10-15 | 2026-10-22 | |
| PQLB vs TFPB in HALDN Quadratus Lumborum Block type 2, Transversalis Fascia Plane Block - Analgesia, Donor Nephrectomy | Not applicable | Not yet recruiting | Koc University Hospital | 54 | 2026-10-01 | 2026-10-08 |
| Precision Analgesia for Cardiac Surgery Analgesia, Cardiac Surgery | Not yet recruiting | Kathirvel Subramaniam | 400 | 2026-10-01 | 2026-09-10 | |
| Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled Trial Esketamine combined with dexmedetomidine, Dexmedetomidine - Dexmedetomidine, Ketamine | Phase 4 | Not yet recruiting | The First Affiliated Hospital with Nanjing Medical University | 356 | 2026-09-28 | 2026-09-03 |
| Postoperative Analgesia Using a Perineural Catheter Versus a Single Nerve Block in Rearfoot Surgery Phone contact, perineural catheter, Regional Anesthesia - Hindfoot Surgery, Analgesia | Recruiting | University Hospital, Angers | 60 | 2026-09-14 | 2026-09-22 | |
| Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm Infants Fentanyl Citrate (Intranasal), Normal Saline (Placebo, Intranasal) - Neonatal Pain, Retinopathy of Prematurity (ROP) | Phase 1 / Phase 2 | Not yet recruiting | Marsha Campbell-Yeo | 58 | 2026-09-09 | 2026-06-30 |
| Tourniquet Pain Prevention During Distal Upper Limb Surgery Selective ultrasound guided Intercostobrachial nerve block, Serratus anterior plane block - Analgesia | Not applicable | Not yet recruiting | Zagazig University | 90 | 2026-09-01 | 2026-08-27 |
| Feasibility of Protocolised Analgosedation in ECMO Sedation protocol - Intensive Care (ICU), Respiratory Distress Syndrome (RDS) | Not applicable | Not yet recruiting | Guy's and St Thomas' NHS Foundation Trust | 60 | 2026-09-01 | 2026-05-12 |
| SPSIP Block for Pain Control After Breast Reduction Surgery Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block, Standard Perioperative Pain Treatment - Postoperative Pain Breast Reduction, Mammaplasty | Not applicable | Recruiting | Cumhuriyet University Hospital | 80 | 2026-08-24 | 2026-08-25 |
| Pericapsular Nerve Group Block Versus Intrathecal Morphine for Pain After Hip Surgery Morpine, Ultrasound-guided pericapsular nerve group block, Bupivacaine - Hip Arthroplasty, Total, Postoperative Pain | Not applicable | Completed | Selcuk University | 64 | 2026-08-24 | 2026-10-08 |
| Ultrasound-Guided Recto-Intercostal Fascial Plane Block in Laparoscopic Cholecystectomy Rectointercostal facial plane block using bupivacaine 0.25% - Analgesia, Pain Management | Not applicable | Recruiting | Istinye University | 60 | 2026-08-06 | 2026-08-10 |
| Evaluation of Three Different Antalgic Blocks in Total Knee Prosthesis Levobupivacaine - Analgesia | Not applicable | Recruiting | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | 142 | 2026-08-06 | 2026-10-23 |
| Ultrasound-Guided Bilateral Transversalis Fascia Plane Block With vs Without Dexamethasone for Cesarean Delivery Pain, Postoperative, Analgesia | Completed | Bahçeşehir University | 93 | 2026-08-03 | 2026-08-18 | |
| Radiofrequency in Knee Osteoarthritis Laser genicular nerve ablation, Conventional radiofrequency genicular nerve ablation - Analgesia | Not applicable | Not yet recruiting | Zagazig University | 50 | 2026-08-01 | 2026-07-14 |
| Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine for Intermediate Cervical Plexus Block Dexmedetomidine Hydrochloride, Dexamethasone Phosphate - Analgesia | Phase 4 | Recruiting | Damanhour Teaching Hospital | 60 | 2026-08-01 | 2026-09-21 |
| Oral Nifedipine Versus Placebo for Pain and Healing After Hemorrhoidectomy Nifedipine 20 Mg, Placebo - Hemorrhoids, Postoperative Pain | Phase 4 | Not yet recruiting | Sana'a University | 100 | 2026-08-01 | 2026-07-01 |
| Analgesia for Perineal Surgeries in High-risk Pediatric Patients Systemic analgesia, Sacral multifidus plane block - Analgesia | Not applicable | Recruiting | Zagazig University | 60 | 2026-07-20 | 2026-08-24 |
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Agnosia (700) · Pain, Postoperative (170) · Acute Pain (59) · Pain (59) · Chronic Pain (25) · Labor Pain (13) · Nociceptive Pain (13) · Patient Satisfaction (12) · Emergencies (10) · Hip Fractures (10) · Postoperative Complications (10) · Postoperative Nausea and Vomiting (10) · Anxiety Disorders (9) · Delirium (9) · Breast Neoplasms (7)
Nervous System Diseases (700) · Neurobehavioral Manifestations (700) · Neurologic Manifestations (700) · Pathological Conditions, Signs and Symptoms (700) · Perceptual Disorders (700) · Signs and Symptoms (700) · Pain (225) · Pathologic Processes (210) · Postoperative Complications (173) · Wounds and Injuries (35) · Mental Disorders (33) · Behavior (29) · Musculoskeletal Diseases (25) · Neoplasms (23) · Neoplasms by Site (20)
Bupivacaine (56) · Dexmedetomidine (40) · Morphine (30) · Acetaminophen (29) · Ropivacaine (29) · Fentanyl (26) · Saline Solution (25) · Dexamethasone (21) · Ketamine (16) · Lidocaine (16) · Sodium Chloride (15) · Ibuprofen (13) · Control Groups (12) · Sufentanil (12) · Dental Occlusion (11)
Tanta University (25) · National Cancer Institute, Egypt (17) · Ataturk University (14) · Zagazig University (14) · Ain Shams University (13) · Assiut University (12) · Aretaieion University Hospital (10) · Heron Therapeutics (9) · Ondokuz Mayıs University (8) · Istanbul University (7) · Mansoura University (6) · Minia University (6) · Peking University First Hospital (6) · Ankara City Hospital Bilkent (5) · Cairo University (5)
Egypt (119) · Turkey (Türkiye) (108) · United States (78) · China (48) · France (31) · Greece (22) · Italy (20) · Canada (19) · Switzerland (17) · Belgium (15) · Germany (14) · Denmark (13) · Taiwan (13) · Spain (11) · Israel (9)
Walaa Y Elsabeeny, MD (9) · Kassiani Theodoraki, PhD, DESA (5) · Rainer Nitzschke, MD (5) · Dong-Xin Wang, MD, PhD (4) · Giuseppe Pascarella, MD (3) · Kassiani Theodoraki (3) · Nazmy S Michael, MD (3) · Ulrike M Stamer, MD (3) · Alshaimaa Kamel, M.D (2) · Anatoly Stav, MD (2)
PMID 26827847, PMID 28067707, PMID 30063657, PMID 34196965, PMID 35143011, PMID 1015603, PMID 11331167, PMID 11331334, PMID 11374619, PMID 11472277, PMID 11589257, PMID 11808971, PMID 12237203, PMID 12411815, PMID 12453928, PMID 12538372, PMID 12548273, PMID 12560416, PMID 12583868, PMID 12626983, PMID 14581113, PMID 14622770, PMID 14639153, PMID 15041597, PMID 15779842, PMID 16249679, PMID 16291387, PMID 16336078, PMID 17138198, PMID 17138203, PMID 17270055, PMID 17270058, PMID 17413915, PMID 17505683, PMID 17625779, PMID 17678782, PMID 18187725, PMID 18514113, PMID 18686750, PMID 18754820, PMID 18762870, PMID 18843636, PMID 18931227, PMID 19157368, PMID 19174373, PMID 19272275, PMID 19274316, PMID 19337241, PMID 19395071, PMID 19478674
2019 (5), 2016 (3), 2025 (2), 1RM1NS128787-01 (1), 2015 (1), 2017 (1), 2023 (1), K23DA044327 (1), K23DA057387 (1)