13 completed, 1 terminated, 1 unknown. 15 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 15 | Completed 13, Terminated 1, Unknown 1 |
Follow Alcohol Abuse: new trials by email Literature Review of Alcohol Abuse trials Research Report on Alcohol Abuse
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Study of Ligustrazine in Treating Alcohol Addiction Ligustrazine by intravenously administration, Ligustrazine by mouth, Placebo by intravenously administration - Alcohol Abuse, Arteriosclerosis | Phase 4 | Unknown | Shenzhen Kangning Hospital | 400 | 2023-07-28 | 2023-10-16 |
| Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT) Isoniazid 300 Mg ORAL TABLET, Pyridoxine 25 Mg Oral Tablet - Tuberculosis, HIV/AIDS | Phase 4 | Completed | University of California, San Francisco | 302 | 2017-04-07 | 2023-10-19 |
| Dutasteride Treatment for the Reduction of Heavy Drinking in Men Dutasteride, sugar pill - Alcoholism, Alcohol Abuse | Phase 4 | Completed | UConn Health | 189 | 2013-01-01 | 2019-04-26 |
| Varenicline in Drug Treatment varenicline, placebo - Smoking Cessation, Alcohol Abuse | Phase 4 | Completed | Centre for Addiction and Mental Health | 33 | 2011-06-01 | 2015-02-05 |
| Placebo-Controlled Cross Over Trial of Chlorzoxazone Intake Parafon Forte - Alcohol Abuse | Phase 4 | Completed | University of California, San Francisco | 48 | 2011-04-01 | 2020-11-20 |
| Dutasteride for the Reduction of Alcohol Use in Male Drinkers Dutasteride, Placebo - Alcoholism, Alcohol Abuse | Phase 4 | Completed | UConn Health | 47 | 2011-01-01 | 2017-03-20 |
| Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy Topiramate, Placebo administration - PTSD, Alcohol Abuse | Phase 4 | Completed | University of California, San Francisco | 30 | 2010-04-01 | 2014-06-03 |
| Efficacy and Tolerability of Topiramate in Treatment of Bipolar Mania and Alcohol Use in Adolescents and Young Adults quetiapine and placebo, Quetiapine and Topiramate - Bipolar Disorder, Alcohol Abuse | Phase 4 | Completed | University of Cincinnati | 56 | 2008-04-01 | 2017-05-23 |
| Acamprosate Added to Escitalopram and Behavioral Treatment for Comorbid Depression and Alcoholism acamprosate, escitalopram, Medical management - Major Depressive Disorder, Alcohol Abuse | Phase 4 | Completed | Massachusetts General Hospital | 23 | 2007-03-01 | 2012-07-09 |
| Zonisamide vs. Placebo in the Treatment of Alcohol Dependence zonisamide, Placebo - Alcoholism, Alcohol Abuse | Phase 4 | Completed | UConn Health | 40 | 2006-07-01 | 2010-10-15 |
| Risperidone Long-acting Versus Oral Risperidone in Patients With Schizophrenia and Alcohol Use Disorder Risperidone Long Acting, oral risperidone - Schizophrenia, Psychotic Disorders | Phase 4 | Completed | Dartmouth-Hitchcock Medical Center | 95 | 2005-09-01 | 2019-05-09 |
| Efficacy of Quetiapine in the Treatment of Patients With Schizophrenia and a Comorbid Substance Use Disorder Quetiapine - Schizophrenia, Schizoaffective Disorder | Phase 4 | Completed | Dartmouth-Hitchcock Medical Center | 23 | 2004-03-01 | 2018-03-14 |
| Naltrexone Treatment of Alcohol Abuse in Schizophrenia Naltrexone or Placebo - Schizophrenia, Mental Disorders | Phase 4 | Completed | State University of New York - Upstate Medical University | 90 | 2003-04-01 | 2013-01-08 |
| Paroxetine for Comorbid Social Anxiety Disorder and Alcoholism Paroxetine, Placebo - Social Anxiety Disorder, Social Phobia | Phase 4 | Completed | Medical University of South Carolina | 42 | 2002-03-01 | 2018-09-27 |
| Alcoholism and Schizophrenia: Effects of Clozapine Clozapine versus typical (conventional) and atypical antipsychotic medications - Schizophrenia, Dual Diagnosis | Phase 4 | Terminated | Dartmouth-Hitchcock Medical Center | 64 | 1999-05-01 | 2018-03-14 |
Alcoholism (15) · Schizophrenia (4) · Psychotic Disorders (3) · Substance-Related Disorders (3) · Acquired Immunodeficiency Syndrome (1) · Alcohol-Related Disorders (1) · Arteriosclerosis (1) · Behavior, Addictive (1) · Bipolar Disorder (1) · Depressive Disorder, Major (1) · Mental Disorders (1) · Phobia, Social (1) · Smoking Cessation (1) · Stress Disorders, Post-Traumatic (1) · Tuberculosis (1)
Chemically-Induced Disorders (15) · Alcohol-Related Disorders (14) · Mental Disorders (14) · Substance-Related Disorders (12) · Schizophrenia Spectrum and Other Psychotic Disorders (4) · Behavior (2) · Mood Disorders (2) · Actinomycetales Infections (1) · Anxiety Disorders (1) · Arterial Occlusive Diseases (1) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Bipolar and Related Disorders (1) · Blood-Borne Infections (1) · Cardiovascular Diseases (1)
Sugars (3) · Dutasteride (2) · Quetiapine Fumarate (2) · Topiramate (2) · Acamprosate (1) · Chlorzoxazone (1) · Congresses as Topic (1) · Escitalopram (1) · Isoniazid (1) · Lactose (1) · Naltrexone (1) · Paroxetine (1) · Practice Management, Medical (1) · Pyridoxine (1) · Qnexa (1)
Dartmouth-Hitchcock Medical Center (3) · UConn Health (3) · University of California, San Francisco (3) · Centre for Addiction and Mental Health (1) · Massachusetts General Hospital (1) · Medical University of South Carolina (1) · Shenzhen Kangning Hospital (1) · State University of New York - Upstate Medical University (1) · University of Cincinnati (1)
United States (12) · Canada (1) · China (1) · Uganda (1)
Alan I Green, MD (2) · Alan I. Green, MD (1) · Albert J. Arias, MD (1) · Carrie L Randall, PhD (1) · Howard Fields, PhD (1) · Janet M Witte, MD (1) · Jonathan Covault, M.D., PhD. (1) · Jonathan Covault, MD, PhD (1) · Judith A Hahn, PhD, MA (1) · Laurie Zawertailo, PhD (1) · Melissa P DelBello, MD (1) · Nicholas Bolo, PhD (1) · Steven L Batki, MD (1) · Steven L. Batki, MD (1) · Xiaojian Jia (1)
PMID 23131884, PMID 26302441, PMID 36044285, PMID 38684046
P60AA003510 (2), M01RR006192 (1), P50AA003510 (1), R01AA013379 (1), R01AA013655 (1), R21AA016372 (1)