1258 completed, 297 unknown, 157 recruiting, 84 not yet recruiting. 430 Not applicable, 363 Phase 2, 312 Phase 3, 241 Phase 1, 164 Phase 4.
Follow Actinomycetales Infections: new trials by email Literature Review of Actinomycetales Infections trials Research Report on Actinomycetales Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Advanced HIV Re-engagement in Care ARC - Advanced HIV Disease | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 724 | 2027-05-01 | 2026-07-23 |
| Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trial Sulbactam 25mg/kg -Durlobactam 25mg/kg (Every 6 hours), Ceftriaxone for Injection, Amoxicillin - Mycobacterium Abscessus Pulmonary Disease, Mycobacterium Abscessus Infection | Phase 2 | Not yet recruiting | The University of Queensland | 300 | 2027-04-01 | 2026-03-20 |
| Therapeutic ID93 + GLA-SE Vaccination in Participants With Rifampicin-Susceptible Pulmonary TB ID93 + GLA-SE vaccine, Placebo vaccine - Tuberculosis, Pulmonary | Phase 2 | Not yet recruiting | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 1500 | 2027-01-31 | 2026-08-24 |
| Safety and Immunogenicity of VPM1002 Vaccination or BCG Revaccination Against TB in Pre-Adolescents Living With and Without HIV in South Africa VPM1002 Vaccine, BCG Vaccine, Placebo - Tuberculosis, HIV Infections | Phase 1 / Phase 2 | Withdrawn | International Maternal Pediatric Adolescent AIDS Clinical Trials Group | 2026-12-31 | 2026-08-17 | |
| Shaping a Community-based Pathway to Improve TB Surveillance Among African and Hindustan Immigrants Experiencing Vulnerabilities Tuberculosis, Tuberculosis (TB) | Not yet recruiting | Universidade Nova de Lisboa | 200 | 2026-12-01 | 2026-07-07 | |
| Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in Children Cryopreserved aorta - Trachea Diseases, Tracheal Stenosis | Not applicable | Enrolling by invitation | National Taiwan University Hospital | 5 | 2026-12-01 | 2026-08-17 |
| A Clinical Study of the HCMV-TB Vaccine Candidate VIR-1778 in Healthy Adults VIR-1778 (5 × 10^5 ffu), VIR-1778 (5 × 10^6 ffu), HT Diluent Placebo - Tuberculosis | Phase 1 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 116 | 2026-11-06 | 2026-09-14 |
| The LalelaLung Study: Digital Stethoscope Clinical Evaluation StethoMe AI-enabled digital stethoscope system, Standard IMCI assessment - Pneumonia, Tuberculosis, Pulmonary | Phase 4 | Not yet recruiting | Johns Hopkins University | 350 | 2026-11-02 | 2026-09-23 |
| China Aortic Infection and Graft Infection Study: An Ambispective Cohort Vascular Graft Infection, Infectious Aortitis | Recruiting | Shanghai Zhongshan Hospital | 2000 | 2026-11-01 | 2026-10-02 | |
| A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB) Isoniazid, Rifampin, Pyrazinamide - Tuberculosis | Phase 2 | Not yet recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 900 | 2026-10-30 | 2026-08-19 |
| A Clinical Study on Immunogenicity Persistence of Adsorbed 5-component Acellular Pertussis, Diphtheria and Tetanus Combined Vaccine Previously received the Tdcp vaccine at age 18 and older, Previously received the Tdcp vaccine at age 12-17, Previously received the Tdcp vaccine at age 6-11 - Diphtheria, Tetanus | Not yet recruiting | CanSino Biologics Inc. | 160 | 2026-10-15 | 2026-08-04 | |
| Integrating Tuberculosis Treatment Into Community Pharmacies to Improve TB/HIV Outcomes in Uganda The intervention is TB treatment delivery via community pharmacies for people with TB/HIV, Control Arm - standard of care - TB - Tuberculosis, HIV - Human Immunodeficiency Virus | Not applicable | Not yet recruiting | Makerere University | 124 | 2026-10-01 | 2026-09-25 |
| Re-evaluating the Duration in Children of TB Treatment Rifampicin, Isoniazid, Pyrazinamide - Tuberculosis | Phase 2 | Not yet recruiting | University of Wisconsin, Madison | 230 | 2026-10-01 | 2026-09-29 |
| Digital Psychosocial Interventions on Stigma and Health Outcomes in TB Patients Online Mindfulness, Online CBT Intervention, Human-computer Interaction - Tuberculosis (TB) | Not applicable | Not yet recruiting | Peking Union Medical College | 496 | 2026-10-01 | 2026-08-03 |
| A 6-Month MDR-END Plus Regimen for Rifampicin-Resistant Tuberculosis MDR-END Plus regimen, Standard-of-care (SoC) treatment - Rifampicin-Resistant Tuberculosis | Phase 3 | Not yet recruiting | Seoul National University Hospital | 294 | 2026-10-01 | 2026-06-30 |
| Study of BK1803 in Healthy Infants BK1803, GOBIK Aqueous Suspension Syringes, Bimmugen® Injection - Pertussis, Diphtheria | Phase 3 | Not yet recruiting | Tanabe Pharma Corporation | 344 | 2026-10-01 | 2026-08-28 |
| STeroids and Enhanced Spectrum Antibiotics for the Treatment of Patients in Africa With Refractory Sepsis Hydrocortisone administration, Expanded antimicrobial therapy - Sepsis, Tuberculosis | Phase 3 | Not yet recruiting | University of Virginia | 344 | 2026-10-01 | 2026-06-01 |
| Plasma MTB cfDNA Before Bronchoscopy Diagnostic Test: Plasma MTB cfDNA assay - Tuberculosis Diagnosis | Not yet recruiting | Chinese University of Hong Kong | 600 | 2026-10-01 | 2025-11-17 | |
| Silymarin Versus N-Acetylcysteine as Protective Effect Against Anti-tuberculosis Drugs Induced Liver Injury. Antituberculosis drugs Group - Drug-Induced Acute Liver Injury, Tuberculosis (TB) | Early Phase 1 | Not yet recruiting | Assiut University | 102 | 2026-10-01 | 2026-10-21 |
| Fibroblast Activating Protein (FAP) PET/CT in Adults With Tuberculosis [18F]-FAPI-74 - Tuberculosis, Pulmonary | Early Phase 1 | Recruiting | University of Pennsylvania | 10 | 2026-09-30 | 2026-09-21 |
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Tuberculosis (1142) · Tuberculosis, Pulmonary (309) · Diphtheria (254) · Tetanus (243) · Latent Tuberculosis (198) · Whooping Cough (160) · HIV Infections (147) · Tuberculosis, Multidrug-Resistant (129) · Acquired Immunodeficiency Syndrome (118) · Poliomyelitis (114) · Hepatitis B (109) · Haemophilus Infections (107) · Mycobacterium avium-intracellulare Infection (66) · Mycobacterium Infections (59) · Mycobacterium Infections, Nontuberculous (54)
Bacterial Infections and Mycoses (1975) · Gram-Positive Bacterial Infections (1972) · Bacterial Infections (1958) · Infections (1958) · Mycobacterium Infections (1655) · Respiratory Tract Diseases (589) · Respiratory Tract Infections (515) · Virus Diseases (393) · Tuberculosis (390) · Lung Diseases (384) · RNA Virus Infections (360) · Blood-Borne Infections (328) · Communicable Diseases (326) · Immune System Diseases (271)
Isoniazid (166) · Rifampin (141) · Pyrazinamide (92) · Ethambutol (87) · bedaquiline (69) · Moxifloxacin (56) · rifapentine (53) · Tetanus Toxoid (50) · Linezolid (48) · pretomanid (38) · Rifabutin (36) · OPC-67683 (34) · Clofazimine (31) · diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine (29) · Levofloxacin (27)
GlaxoSmithKline (116) · National Institute of Allergy and Infectious Diseases (NIAID) (113) · Sanofi Pasteur, a Sanofi Company (58) · University of Oxford (39) · Johns Hopkins University (37) · Global Alliance for TB Drug Development (31) · Centers for Disease Control and Prevention (29) · University of Cape Town (28) · National Taiwan University Hospital (24) · Aeras (23) · Beijing Chest Hospital (22) · Sanofi (20) · Seoul National University Hospital (20) · Assistance Publique - Hôpitaux de Paris (19) · Huashan Hospital (18)
South Africa (284) · United States (280) · China (140) · Uganda (107) · India (102) · South Korea (88) · United Kingdom (82) · Brazil (71) · Tanzania (61) · Canada (56) · France (56) · Indonesia (56) · Thailand (56) · Taiwan (54) · Philippines (51)
Helen McShane (20) · Nicholas Paton (10) · Clifton E Barry, Ph.D. (8) · Jae-Joon Yim, MD (8) · Susan Dorman, MD (8) · Andreas Diacon, MD (6) · Chin-Chung Shu, MD (6) · Grant Theron, PhD (6) · Marc Weiner, MD (6) · Dick Menzies, MD (5)
PMID 33616229, PMID 40122135, PMID 25466778, PMID 36808186, PMID 28043488, PMID 28063795, PMID 33542052, PMID 17716936, PMID 17957238, PMID 19529780, PMID 19880906, PMID 20442432, PMID 20629533, PMID 21215445, PMID 22150035, PMID 23691171, PMID 23979737, PMID 24675585, PMID 24874401, PMID 25114140, PMID 25359354, PMID 25882172, PMID 25904367, PMID 26400476, PMID 26647431, PMID 27097163, PMID 27243774, PMID 27868466, PMID 28216183, PMID 28340322, PMID 29393655, PMID 30102705, PMID 30216086, PMID 31866327, PMID 32539440, PMID 32785709, PMID 32934758, PMID 33283229, PMID 33595792, PMID 34021314, PMID 34929010, PMID 35404075, PMID 35850123, PMID 36053506, PMID 36546625, PMID 36560565, PMID 36730240, PMID 36949623, PMID 37035978, PMID 37980911
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