16 completed, 8 unknown, 3 not yet recruiting, 2 active not recruiting. 33 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 33 | Completed 16, Unknown 8, Not yet recruiting 3, Active not recruiting 2, Recruiting 2, Enrolling by invitation 1, Withdrawn 1 |
Follow Acute Appendicitis: new trials by email Literature Review of Acute Appendicitis trials Research Report on Acute Appendicitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Laparoscopic vs Open Appendectomy in Obese Patients Open Appendectomy, Laparoscopic Appendectomy - Acute Appendicitis, Appendicitis (Diagnosis) | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 166 | 2026-10-02 | 2026-09-16 |
| Immediate Laparoscopic Appendectomy Versus Interval Laparoscopic Appendectomy for Early Appendicular Mass Immediate Laparoscopic Appendectomy, Interval Laparoscopic Appendectomy - Appendicular Mass, Acute Appendicitis | Not applicable | Not yet recruiting | Assiut University | 100 | 2026-10-01 | 2026-09-23 |
| Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic Appendectomy Comprehensive 20-Item Pediatric ERAS Protocol - Appendectomy, Laparoscopic, Acute Appendicitis | Not applicable | Recruiting | Ahmet Burak Doğan, MD | 100 | 2026-06-15 | 2026-10-15 |
| TACTILE : Validation of a Teleconsultation-Based Predictive Score for the Diagnosis of Acute Appendicitis in Children Using Artificial Intelligence Methods Score-based appendicitis risk classification in teleconsultation - Acute Appendicitis | Not applicable | Not yet recruiting | University Hospital, Angers | 1500 | 2026-06-01 | 2026-03-18 |
| Laparoscopic vs Open Appendectomy Laparoscopic appendectomy, Open Appendectomy - Acute Appendicitis, Superficial SSI | Not applicable | Completed | Quaid-e-Azam Medical College | 276 | 2026-01-24 | 2026-09-25 |
| Artificial Intelligence-driven Virtual Standardized Pediatric Patients Trial Virtual standardized patients (VSPs), Case teaching manuals, Case teaching videos - Pneumococcal Pneumonia, Rotavirus Enteritis With Hypovolemic Shock | Not applicable | Recruiting | Southern Medical University, China | 459 | 2024-12-01 | 2024-12-19 |
| Antibiotics vs Surgery in Acute Appendicitis surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines, Antibiotic - Acute Appendicitis | Not applicable | Active not recruiting | Sebahattin Celik MD | 400 | 2024-11-04 | 2026-03-25 |
| Efficacy of Transversus Abdominis Plane Block in Alleviating Acute Appendicitis Transversus Abdominis Plane Blockage - Acute Appendicitis | Not applicable | Completed | Ankara City Hospital Bilkent | 105 | 2024-05-08 | 2026-06-04 |
| Clinical Trial for a Outpatient Clinical Management for Complicated Acute Appendicitis Hospitalization, Outpatient - Acute Appendicitis, Appendicitis Perforated | Not applicable | Unknown | HJ23 | 92 | 2023-11-01 | 2023-09-28 |
| IA Model for Acute Appendicitis in CT Information of Appendix (IA) model - Acute Appendicitis | Not applicable | Unknown | Hallym University Medical Center | 568 | 2023-07-04 | 2023-12-18 |
| "Stump-First" Approach in Laparoscopic Appendectomy Classic Approach in Laparoscopic Appendectomy, Stump first Approach in Laparoscopic Appendectomy - Acute Appendicitis, Acute Appendicitis with Appendix Abscess | Not applicable | Completed | Izmir City Hospital | 78 | 2023-04-01 | 2025-03-27 |
| Short Post-operative Antibacterial Therapy in Complicated Appendicitis: Oral Versus Intravenous Oral versus intravenous administration of antibacterial treatment - Acute Appendicitis, Acute Appendicitis With Rupture | Not applicable | Unknown | North Estonia Medical Centre | 100 | 2020-11-01 | 2021-07-01 |
| Endoscopic Retrograde Appendicitis Therapy Endoscopic retrograde appendicitis therapy - Acute Appendicitis | Not applicable | Completed | Chinese University of Hong Kong | 20 | 2020-06-01 | 2023-02-08 |
| Presentation and Outcomes of Acute Appendicitis During COVID Pandemic appendectomy - Acute Appendicitis | Not applicable | Completed | Mansoura University | 1945 | 2019-03-31 | 2021-11-08 |
| Optimizing the Diagnosis of Acute Appendicitis Observation - Acute Appendicitis | Not applicable | Unknown | Vilnius University | 200 | 2018-12-01 | 2019-10-07 |
| Technical Modifications of Appendicular Stump Closure During Laparoscopic Appendectomy Stapler appendectomy, Endoloop, Hem-O-Lock - Acute Appendicitis | Not applicable | Completed | University Hospital Ostrava | 120 | 2018-06-01 | 2020-10-06 |
| Preoperative Immature Granulocyte Count and Percentage for Acute Appendisitis Appendectomy - Acute Appendicitis | Not applicable | Completed | Kahramanmaras Sutcu Imam University | 70 | 2018-06-01 | 2023-10-17 |
| Laparoscopic-Assisted TAP Block VErsus Trocar-site Infiltration After Laparoscopic Appendectomy laparoscopic-assisted transversus abdominis plane block, trocar-site local anesthetic infiltration - Acute Appendicitis | Not applicable | Completed | Fatih Sultan Mehmet Training and Research Hospital | 60 | 2017-08-16 | 2026-09-30 |
| Antibiotics vs. Placebo in Acute Uncomplicated Appendicitis Ertapenem, Placebo - Acute Appendicitis | Not applicable | Enrolling by invitation | Turku University Hospital | 147 | 2017-08-09 | 2020-11-10 |
| Modified Enhanced Recovery Program in Emergency Surgery (MERES) Laparoscopic appendectomy - Acute Appendicitis, Acute Appendicitis With Rupture | Not applicable | Completed | Pirogov Russian National Research Medical University | 122 | 2017-07-01 | 2018-11-27 |
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Appendicitis (33) · Pain, Postoperative (2) · Abscess (1) · Agnosia (1) · Disease (1) · Emergencies (1) · Hand, Foot and Mouth Disease (1) · Obesity (1) · Pneumonia, Pneumococcal (1) · Respiratory Insufficiency (1)
Cecal Diseases (33) · Digestive System Diseases (33) · Gastroenteritis (33) · Gastrointestinal Diseases (33) · Infections (33) · Intestinal Diseases (33) · Intraabdominal Infections (33) · Pathologic Processes (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (4) · Neurologic Manifestations (3) · Pain (2) · Postoperative Complications (2) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1)
Appendectomy (4) · Ertapenem (3) · Metronidazole (3) · Levofloxacin (2) · Moxifloxacin (2) · Amoxicillin (1) · Amoxicillin-Potassium Clavulanate Combination (1) · Anti-Bacterial Agents (1) · Hospitalization (1) · Models, Biological (1) · Observation (1) · Oxygen (1) · Piperacillin (1) · Piperacillin, Tazobactam Drug Combination (1) · Saline Solution (1)
Turku University Hospital (4) · Mansoura University (2) · Ahmet Burak Doğan, MD (1) · Ankara City Hospital Bilkent (1) · Assiut University (1) · Bezmialem Vakif University (1) · Chinese University of Hong Kong (1) · Fatih Sultan Mehmet Training and Research Hospital (1) · HJ23 (1) · Hallym University Medical Center (1) · Izmir City Hospital (1) · Kahramanmaras Sutcu Imam University (1) · Maltepe University (1) · National Taiwan University Hospital (1) · North Estonia Medical Centre (1)
Turkey (Türkiye) (7) · Finland (4) · China (2) · United States (2) · Czechia (1) · Egypt (1) · Estonia (1) · France (1) · Hong Kong (1) · Israel (1) · Lithuania (1) · Pakistan (1) · Russia (1) · Singapore (1) · South Korea (1)
Paulina Salminen, MD, PhD (3) · Abut Kebudi, Prof. (1) · Ahmet Burak Erdem, Assoc. Prof. (1) · Alexander V Sazhin, Prof. (1) · Arthur Rawlings, MD (1) · Edgar Lipping, MD (1) · Fatih Altintoprak, Assoc.Prof. (1) · Francois I. Luks, MD, PhD (1) · Huseyin K Bektasoglu, MD (1) · Iltae Son (1) · Jordi Elvira Lopez, MD, PhD (1) · Manuk Norayk Manukyan, Assoc.Prof. (1)
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