62 completed, 16 unknown, 7 recruiting, 4 active not recruiting. 33 Not applicable, 5 Phase 2, 5 Phase 3, 5 Phase 4, 1 Phase 1.
Follow Acute Appendicitis: new trials by email Literature Review of Acute Appendicitis trials Research Report on Acute Appendicitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Laparoscopic vs Open Appendectomy in Obese Patients Open Appendectomy, Laparoscopic Appendectomy - Acute Appendicitis, Appendicitis (Diagnosis) | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 166 | 2026-10-02 | 2026-09-16 |
| Patient Choice Between Antibiotics and Appendectomy in Uncomplicated Appendicitis (FRENCH 47 - ALACARTE) Shared decision-making, amoxicillin-clavulanate, Appendectomy - Acute Appendicitis | Phase 2 | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 560 | 2026-10-01 | 2026-10-05 |
| Immediate Laparoscopic Appendectomy Versus Interval Laparoscopic Appendectomy for Early Appendicular Mass Immediate Laparoscopic Appendectomy, Interval Laparoscopic Appendectomy - Appendicular Mass, Acute Appendicitis | Not applicable | Not yet recruiting | Assiut University | 100 | 2026-10-01 | 2026-09-23 |
| Prospective Comparison of Pro-Adrenomedullin, C-Reactive Protein, and Neutrophil-to-Lymphocyte Ratio for Diagnosing Acute Appendicitis Serum Pro-Adrenomedullin Measurement - Acute Appendicitis | Recruiting | Bursa Yuksek Ihtisas Training and Research Hospital | 400 | 2026-08-01 | 2026-10-26 | |
| Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic Appendectomy Comprehensive 20-Item Pediatric ERAS Protocol - Appendectomy, Laparoscopic, Acute Appendicitis | Not applicable | Recruiting | Ahmet Burak Doğan, MD | 100 | 2026-06-15 | 2026-10-15 |
| TACTILE : Validation of a Teleconsultation-Based Predictive Score for the Diagnosis of Acute Appendicitis in Children Using Artificial Intelligence Methods Score-based appendicitis risk classification in teleconsultation - Acute Appendicitis | Not applicable | Not yet recruiting | University Hospital, Angers | 1500 | 2026-06-01 | 2026-03-18 |
| Comparative Study on the Diagnostic Validity of the Alvarado Score, Appendicitis Inflammatory Response (AIR), and Adult Appendicitis Score (AAS) in Acute Appendicitis at East Lancashire Hospitals NHS Trust (ELHT) Acute Appendicitis | Completed | East Lancashire Hospitals NHS Trust | 300 | 2026-04-13 | 2026-09-04 | |
| Comparison of Diagnostic Methods in Patients Operated for Suspected Appendicitis Acute Appendicitis | Recruiting | Sanliurfa Education and Research Hospital | 200 | 2026-03-18 | 2026-04-01 | |
| Laparoscopic vs Open Appendectomy Laparoscopic appendectomy, Open Appendectomy - Acute Appendicitis, Superficial SSI | Not applicable | Completed | Quaid-e-Azam Medical College | 276 | 2026-01-24 | 2026-09-25 |
| Prostaglandin-E Urinary Metabolite (PGE-M) as a Predictor of Acute Appendicitis in Children Blood specimen collection, Urine collection - Acute Appendicitis, Acute Appendicitis With Rupture | Recruiting | KBC Split | 100 | 2025-06-02 | 2025-06-06 | |
| Clinical Diagnosis of Acute Appendicitis with Normal WBCS Count with Role of Inflammatory Markers and Radiology Appendectomy - Acute Appendicitis | Active not recruiting | Assiut University | 50 | 2025-01-01 | 2025-02-19 | |
| Artificial Intelligence-driven Virtual Standardized Pediatric Patients Trial Virtual standardized patients (VSPs), Case teaching manuals, Case teaching videos - Pneumococcal Pneumonia, Rotavirus Enteritis With Hypovolemic Shock | Not applicable | Recruiting | Southern Medical University, China | 459 | 2024-12-01 | 2024-12-19 |
| Retrospective Acute Care Appendectomy Study Appendectomy - Acute Appendicitis | Active not recruiting | Intuitive Surgical | 1000 | 2024-11-22 | 2026-09-24 | |
| Antibiotics vs Surgery in Acute Appendicitis surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines, Antibiotic - Acute Appendicitis | Not applicable | Active not recruiting | Sebahattin Celik MD | 400 | 2024-11-04 | 2026-03-25 |
| Are Double-ring Wound-edge Protectors Effective for Preventing Superficial Surgical Site Infection After Open Appendectomy? Double-ring wound-edge protector - Acute Appendicitis, Surgical Site Infection | Unknown | Hospital Medina del Campo | 671 | 2024-10-25 | 2023-12-07 | |
| Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy Intravenous magnesium sulfate, Normal saline infusion - Opioid Consumption, Multimodal Analgesia | Phase 4 | Recruiting | Medical University of Warsaw | 188 | 2024-09-09 | 2026-08-20 |
| Efficacy of Transversus Abdominis Plane Block in Alleviating Acute Appendicitis Transversus Abdominis Plane Blockage - Acute Appendicitis | Not applicable | Completed | Ankara City Hospital Bilkent | 105 | 2024-05-08 | 2026-06-04 |
| Management of Acute Appendicitis Pain in the Emergency Department Transversus abdominis plane blockage, Erector spinae plane blockage, Tramadol - Acute Appendicitis | Completed | Ankara City Hospital Bilkent | 96 | 2024-05-08 | 2026-02-20 | |
| Prioritisation of Acute Appendicitis Using Appendistat Score Acute Appendicitis, Acute Appendicitis With Rupture | Completed | University College, London | 592 | 2024-01-06 | 2025-09-29 | |
| Clinical Trial for a Outpatient Clinical Management for Complicated Acute Appendicitis Hospitalization, Outpatient - Acute Appendicitis, Appendicitis Perforated | Not applicable | Unknown | HJ23 | 92 | 2023-11-01 | 2023-09-28 |
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Appendicitis (99) · Abdominal Pain (6) · Disease (6) · Pain, Postoperative (5) · Abdomen, Acute (3) · Cholecystitis, Acute (3) · Emergencies (3) · Acute Pain (2) · Agnosia (2) · Pancreatitis (2) · Surgical Wound Infection (2) · Abscess (1) · Anxiety Disorders (1) · COVID-19 (1) · Foreign Bodies (1)
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Appendectomy (12) · Metronidazole (6) · Ertapenem (4) · Amoxicillin-Potassium Clavulanate Combination (3) · Blood Specimen Collection (3) · Levofloxacin (3) · Amoxicillin (2) · Anti-Bacterial Agents (2) · Laparoscopy (2) · Moxifloxacin (2) · Saline Solution (2) · Surgical Procedures, Operative (2) · Ambulatory Surgical Procedures (1) · Benchmarking (1) · Ceftriaxone (1)
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