34 completed, 6 unknown, 2 terminated, 1 recruiting. 11 Phase 4, 10 Phase 1, 8 Phase 3, 6 Not applicable, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 11 | Completed 8, Unknown 2, Terminated 1 |
| Phase 1 | 10 | Completed 8, Unknown 2 |
| Phase 3 | 8 | Completed 7, Unknown 1 |
| Not applicable | 6 | Completed 4, Recruiting 1, Withdrawn 1 |
| Phase 2 | 5 | Completed 5 |
Follow Pneumonia, Pneumococcal: new trials by email Literature Review of Pneumonia, Pneumococcal trials Research Report on Pneumonia, Pneumococcal
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Artificial Intelligence-driven Virtual Standardized Pediatric Patients Trial Virtual standardized patients (VSPs), Case teaching manuals, Case teaching videos - Pneumococcal Pneumonia, Rotavirus Enteritis With Hypovolemic Shock | Not applicable | Recruiting | Southern Medical University, China | 459 | 2024-12-01 | 2024-12-19 |
| Study of Gamma PN3 in the Elderly Gamma PN3, Prevnar - Pneumonia, Pneumococcal | Phase 1 | Completed | GPN Vaccines | 105 | 2024-08-26 | 2025-05-11 |
| Pneumonia Vaccine Education Intervention Study Pneumococcal Vaccine Education - Pneumonia, Pneumococcal, Vaccine | Not applicable | Completed | Geisinger Clinic | 141 | 2024-05-06 | 2025-07-08 |
| Text Message-Based Nudges Prior to Primary Care Visits to Increase Care Gap Closure Text message nudge - Pneumonia, Pneumococcal, Diabetes Mellitus | Not applicable | Completed | Mitesh Patel | 29334 | 2023-09-05 | 2024-04-25 |
| Phase I Clinical Trial of a Candidate PCV13 in Healthy People 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine - Pneumococcal Infections | Phase 1 | Unknown | Wuhan BravoVax Co., Ltd. | 264 | 2022-11-01 | 2022-11-17 |
| A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 When Administered Concomitantly With Influenza Vaccine in Adults 50 Years of Age or Older (V116-005, STRIDE-5) V116, QIV, Matching Placebo for V116 - Pneumonia, Pneumococcal | Phase 3 | Completed | Merck Sharp & Dohme LLC | 1080 | 2022-09-23 | 2025-10-29 |
| A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 in Pneumococcal Vaccine-experienced Adults (V116-006, STRIDE-6) V116, PCV15, PPSV23 - Pneumonia, Pneumococcal | Phase 3 | Completed | Merck Sharp & Dohme LLC | 717 | 2022-07-12 | 2024-10-26 |
| Pneumococcal Community-Acquired Pneumonia Requiring Hospitalization Among Colombian Adults Community Acquired Pneumonia (CAP), Pneumococcal Pneumonia | Completed | Universidad de la Sabana | 688 | 2022-06-28 | 2026-01-21 | |
| A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy Infants AFX3772, Prevnar 13, Prevnar 20 - Pneumonia, Bacterial, Pneumococcal Infections | Phase 2 | Completed | GlaxoSmithKline | 388 | 2022-06-16 | 2026-10-09 |
| Paediatric Pneumococcal Pneumonia in Malaysia Prior to and During Pneumococcal Conjugate Vaccine (PCV) Implementation Pneumonia, Pneumococcal, Pneumonia Childhood | Unknown | IMU University, Malaysia | 1010 | 2021-10-13 | 2024-01-18 | |
| Evaluation of Immunogenicity and Safety of Combined Immunization of COVAX (Produced in Wuhan) and PPV23 / IIV4 COVAX+PPV23;COVAX+IIV4, COVAX only (1st and 2nd dose), PPV23 for the 1st dose and IIV4 for the 2nd dose - Influenza, Human, Pneumonia, Pneumococcal | Phase 4 | Unknown | China National Biotec Group Company Limited | 1404 | 2021-05-06 | 2021-10-15 |
| Evaluation of Immunogenicity and Safety of Combined Immunization of COVID-19 Vaccine (Produced in Beijing) and PPV23 / IIV4 COVAX+IIV4; COVAX+PPV23, COVAX only (1st and 2nd dose), IIV4 for the 1st dose and PPV23 for the 2nd dose - Influenza, Human, Pneumonia, Pneumococcal | Phase 4 | Completed | China National Biotec Group Company Limited | 1133 | 2021-03-10 | 2021-10-20 |
| Prevention of Missed Opportunities for HIV Diagnosis by Promoting HIV Testing of Patients With Pneumococcal Pneumonia at Nice University Hospital (PneumoVIH) HIV testing - Pneumonia, Pneumococcal, Hiv | Completed | Centre Hospitalier Universitaire de Nice | 94 | 2020-12-01 | 2025-03-04 | |
| Evaluation of Safety and Immunogenicity of Combined Immunization of PPV23 and IIV4 IIV4 and PPV23, IIV4, PPV23 - Influenza, Human, Pneumonia, Pneumococcal | Phase 4 | Completed | China National Biotec Group Company Limited | 1224 | 2020-09-11 | 2022-08-02 |
| Immunogenicity and Safety Study of 15-Valent Pneumococcal Conjugate Vaccine in 2-month-old and 3-month-old Healthy Volunteers 15-Valent Pneumococcal Conjugate Vaccine, 13-Valent Pneumococcal Conjugate Vaccine - Pneumonia, Pneumococcal | Phase 3 | Unknown | Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd | 1950 | 2020-07-01 | 2020-04-22 |
| A Phase 1/Phase 2 Study of Polyvalent Pneumococcal Conjugate Vaccine (V116) in Adults (V116-001) V116, Pneumovax™23 - Pneumonia, Pneumococcal | Phase 1 / Phase 2 | Completed | Merck Sharp & Dohme LLC | 600 | 2019-12-06 | 2022-09-16 |
| Study of 10-valent Pneumococcal Conjugate Vaccine (Pneumosil) Administered in a 2+1 Schedule to Healthy Infants Pneumosil, Prevenar 13, Synflorix - Pneumonia, Pneumococcal | Phase 3 | Completed | PATH | 660 | 2019-07-18 | 2022-04-20 |
| Lot-to-Lot Consistency of V114 in Healthy Adults (V114-020) V114, Prevnar 13™ - Pneumococcal Infections, Pneumonia, Pneumococcal | Phase 3 | Completed | Merck Sharp & Dohme LLC | 2340 | 2019-06-12 | 2021-04-12 |
| Safety Study of 15-Valent Pneumococcal Conjugate Vaccine in Healthy Volunteers Aged Above 2 Months 15-Valent Pneumococcal Conjugate Vaccine - Pneumonia, Pneumococcal | Phase 1 | Unknown | Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd | 80 | 2019-06-05 | 2019-09-30 |
| An Epidemiological Survey to Establish the Spectrum of Circulating Serotypes of S. Pneumoniae, in Patients Older 18 Years Detection of Streptococcus pneumoniae strains - Pneumonia, Pneumococcal, Invasive Pneumococcal Disease | Not applicable | Completed | The Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy (IACMAC) | 500 | 2019-06-01 | 2021-02-11 |
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Pneumococcal Infections (10) · Influenza, Human (5) · Pneumonia (5) · Community-Acquired Pneumonia (3) · Pneumonia, Bacterial (2) · Acquired Immunodeficiency Syndrome (1) · Appendicitis (1) · Breast Neoplasms (1) · COVID-19 (1) · Colorectal Neoplasms (1) · Community-Acquired Infections (1) · Diabetes Mellitus (1) · Febrile Neutropenia (1) · Gram-Positive Bacterial Infections (1)
Bacterial Infections (44) · Bacterial Infections and Mycoses (44) · Lung Diseases (44) · Respiratory Tract Diseases (44) · Respiratory Tract Infections (44) · Gram-Positive Bacterial Infections (43) · Infections (43) · Streptococcal Infections (43) · Pneumonia, Bacterial (42) · Pneumonia (39) · Pneumococcal Infections (34) · RNA Virus Infections (7) · Virus Diseases (7) · Orthomyxoviridae Infections (5) · Immune System Diseases (4)
Pneumococcal Vaccines (7) · PHiD-CV vaccine (5) · 13-valent pneumococcal vaccine (4) · Heptavalent Pneumococcal Conjugate Vaccine (4) · 23-valent pneumococcal capsular polysaccharide vaccine (3) · 10-valent pneumococcal conjugate vaccine (2) · Sodium Chloride (2) · Anti-Bacterial Agents (1) · Ceftriaxone (1) · Echocardiography (1) · Granulocyte-Macrophage Colony-Stimulating Factor (1) · HIV Testing (1) · Hepatitis A Vaccines (1) · Influenza Vaccines (1) · Lamivudine (1)
Merck Sharp & Dohme LLC (4) · Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd (3) · China National Biotec Group Company Limited (3) · PATH (3) · Pfizer (3) · KEMRI-Wellcome Trust Collaborative Research Program (2) · Sanofi (2) · Alejandro Rodriguez Oviedo , MD (1) · Centre Hospitalier Universitaire de Nice (1) · GPN Vaccines (1) · Geisinger Clinic (1) · Genocea Biosciences, Inc. (1) · GlaxoSmithKline (1) · Helsinki University Central Hospital (1) · Hospital Mutua de Terrassa (1)
United States (12) · China (8) · Spain (4) · Kenya (3) · Switzerland (3) · Australia (2) · Finland (2) · France (2) · Japan (2) · Netherlands (2) · Taiwan (2) · The Gambia (2) · United Kingdom (2) · Belarus (1) · Canada (1)
Du Lin, Master (3) · Alejandro H Rodriguez Oviedo (1) · Amar Safdar, MD (1) · Anatoly Uss, MD/PhD (1) · Anthony Scott, MD, PhD (1) · Anu Kantele, MD PhD (1) · Cristian C Serrano, MD, cPhD (1) · Daniel M Musher (1) · Ed Clarke (1) · Ed Clarke, MB ChB, PhD (1) · Havlir D (1)
PMID 14998500, PMID 18470901, PMID 20686433, PMID 23123106, PMID 23131206, PMID 23153437, PMID 24086113, PMID 24465570, PMID 25785969, PMID 26083474, PMID 28173960, PMID 28410813, PMID 29017280, PMID 29429807, PMID 29472635, PMID 29561248, PMID 30898094, PMID 32192948, PMID 32418789, PMID 33516293, PMID 35039194, PMID 35931636, PMID 36116461, PMID 36638819, PMID 37780234, PMID 39082735, PMID 39164673, PMID 39602629, PMID 40396505, PMID 40423396, PMID 40714528, PMID 41680649, PMID 42202846
2014 (1), 2018 (1), 2023 (1)