8 completed, 7 unknown, 2 recruiting, 2 terminated. 19 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 19 | Completed 8, Unknown 7, Recruiting 2, Terminated 2 |
Follow Ventricular Remodeling: new trials by email Literature Review of Ventricular Remodeling trials Research Report on Ventricular Remodeling
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Losartan on the Neurohumoral Axis and Ventricular Remodeling of Patients With Severe Aortic Regurgitation Undergoing Valve Surgery. Losartan 50 mg, Placebo - Heart Valve Diseases, Left Ventricle Remodeling | Phase 4 | Recruiting | Vitor Emer Egypto Rosa | 60 | 2025-07-01 | 2025-08-01 |
| Henagliflozin Reducing Infarct Size After Priamry PCI in Patients With ST Segment Elevation Myocardial Infarction Henagliflozin - Myocardial Infarction, Heart Failure | Phase 4 | Completed | Qian geng | 248 | 2023-07-01 | 2025-12-02 |
| Effect of Very Early and Rapid Lowering Cholesterol With Evolocumab on Left Ventricular Remodeling in Patients With Anterior STEMI Undergoing Primary PCI Rosuvastatin 20 mg, Evolocumab 140 mg/1 ml Subcutaneous Solution [REPATHA] - ST Elevation Myocardial Infarction (STEMI) | Phase 4 | Terminated | Henan Institute of Cardiovascular Epidemiology | 119 | 2023-04-03 | 2026-05-22 |
| Effect of Colchicine on MMP-9, NOX2, and TGF-β1 in Myocardial Infarct Colchicine, Percutaneous Coronary Intervention, Optimal medical treatment including statin, aspirin, P2Y12 inhibitor, and nitrate. - ST Elevation Myocardial Infarction, Colchicine | Phase 4 | Unknown | RSD dr. Soebandi | 148 | 2022-06-01 | 2023-04-11 |
| Comparison of the Effects of Dapagliflozin and Gemigliptin on Ketone Metabolism and Cardiac Remodeling in Type 2 Diabetes Dapagliflozin, Gemigliptin - Type2 Diabetes, Remodeling, Ventricular | Phase 4 | Unknown | Wonju Severance Christian Hospital | 122 | 2022-01-07 | 2023-08-01 |
| The Impact of Compound Danshen Dropping Pills (CDDP) on the Post-myocardial Infarction Ventricular Remodeling Compound Danshen Dropping Pills (CDDP), Placebo - Myocardial Infarction | Phase 4 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 268 | 2021-08-25 | 2023-04-11 |
| Angiotensin Receptor Blockers in Aortic Stenosis Angiotensin Receptor Blockers, Placebo - Aortic Stenosis, Aortic Valve Stenosis | Phase 4 | Recruiting | Institut universitaire de cardiologie et de pneumologie de Québec, University Laval | 144 | 2020-02-01 | 2024-12-20 |
| Early rhBNP on Myocardial Remodeling and Reperfusion in Patients With STEMI rhBNP, Control - ST Segment Elevated Myocardial Infarction | Phase 4 | Unknown | RenJi Hospital | 352 | 2019-06-19 | 2023-06-01 |
| Renin-angiotensin System Blockade Benefits in Clinical Evolution and Ventricular Remodeling After Transcatheter Aortic Valve Implantation (RASTAVI) Ramipril - Transcatheter Aortic Valve Replacemen, Angiotensin-Converting Enzyme Inhibitors | Phase 4 | Unknown | Hospital Clínico Universitario de Valladolid | 194 | 2018-02-10 | 2021-09-24 |
| Peripartum Cardiomyopathy in Nigeria Registry Oral Sodium Selenite 200 µg/day for 3 months - Peripartum Cardiomyopathy | Phase 4 | Completed | Aminu Kano Teaching Hospital | 100 | 2017-06-12 | 2021-01-22 |
| Valsartan to Prevent Left Ventricle Remodeling in Pacemaker Patients placebo/valsartan - First Time Dual Chamber Pacemaker Implantation | Phase 4 | Terminated | Medical University of Silesia | 88 | 2017-01-01 | 2023-04-12 |
| Pulse Reduction On Beta-blocker and Ivabradine Therapy Ivabradine, Placebo - Dilated Cardiomyopathies, Idiopathic, Heart Failure, Systolic | Phase 4 | Completed | University of Colorado, Denver | 28 | 2016-11-01 | 2023-12-20 |
| Sodium Tanshinone IIA Sulfonate in Left Ventricular Remodeling Secondary to Acute Myocardial Infarction sodium tanshinone IIA sulfonate, control - Left Ventricular Remodeling, Acute Myocardial Infarction | Phase 4 | Unknown | Guangdong Provincial Hospital of Traditional Chinese Medicine | 60 | 2015-12-01 | 2016-09-01 |
| Ticagrelor Versus Clopidogrel in Left Ventricular Remodeling After ST-segment Elevation Myocardial Infarction Ticagrelor, Clopidogrel - ST Elevation Myocardial Infarction | Phase 4 | Unknown | Gyeongsang National University Hospital | 326 | 2014-10-01 | 2016-11-15 |
| Danlou Tablets to Prevent Left Ventricular Remodeling Danlou Tablets, Placebo - Left Ventricular Remodeling, Acute Myocardial Infarction | Phase 4 | Completed | shuai Mao | 82 | 2012-01-01 | 2016-02-05 |
| Efficacy and Safety of Valsartan Plus Hydrochlorothiazide in Patients With Slight Hypertension and Target Organ Damage Valsartan 160mg plus HCT 25mg - Hypertension, Ventricular Remodeling | Phase 4 | Completed | Federico II University | 20 | 2008-03-01 | 2009-01-29 |
| Statin Therapy in Heart Failure: Potential Mechanisms of Benefit atorvastatin, placebo - Heart Failure, Congestive | Phase 4 | Completed | University of California, Los Angeles | 27 | 2005-08-01 | 2020-03-20 |
| Thrombectomy and Improvement of Left Ventricular Function in AMI Export catheter (Medtronic) - Acute Myocardial Infarction, Ventricular Remodeling | Phase 4 | Completed | R&D Cardiologie | 50 | 2004-04-01 | 2006-02-08 |
| Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart Carvedilol, Metoprolol succinate, Metoprolol succinate + doxazosin - Idiopathic Dilated Cardiomyopathy | Phase 4 | Completed | University of Colorado, Denver | 56 | 2000-09-01 | 2023-11-29 |
Heart Failure (3) · Myocardial Infarction (3) · ST Elevation Myocardial Infarction (3) · Cardiomyopathy, Dilated (2) · Heart Valve Diseases (2) · Aortic Valve Insufficiency (1) · Aortic Valve Stenosis (1) · Atrial Remodeling (1) · Camurati-Engelmann Syndrome (1) · Erectile Dysfunction (1) · Heart Failure, Systolic (1) · Hypertension (1) · Peripartum Cardiomyopathy (1)
Pathological Conditions, Anatomical (19) · Pathological Conditions, Signs and Symptoms (19) · Cardiovascular Diseases (13) · Heart Diseases (12) · Pathologic Processes (7) · Vascular Diseases (7) · Infarction (6) · Ischemia (6) · Myocardial Ischemia (6) · Necrosis (6) · Cardiomyopathies (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Genetic Diseases, Inborn (3) · Myocardial Infarction (3) · Aortic Valve Disease (2)
Valsartan (2) · Angiotensin Receptor Antagonists (1) · Aspirin (1) · Atorvastatin (1) · Carvedilol (1) · Clopidogrel (1) · Colchicine (1) · Doxazosin (1) · Hematocrit (1) · Ivabradine (1) · LC15-0444 (1) · Losartan (1) · Metoprolol (1) · Nitrates (1) · Percutaneous Coronary Intervention (1)
University of Colorado, Denver (2) · Aminu Kano Teaching Hospital (1) · Federico II University (1) · Guangdong Provincial Hospital of Traditional Chinese Medicine (1) · Gyeongsang National University Hospital (1) · Henan Institute of Cardiovascular Epidemiology (1) · Hospital Clínico Universitario de Valladolid (1) · Institut universitaire de cardiologie et de pneumologie de Québec, University Laval (1) · Medical University of Silesia (1) · Qian geng (1) · R&D Cardiologie (1) · RSD dr. Soebandi (1) · RenJi Hospital (1) · The First Affiliated Hospital with Nanjing Medical University (1) · University of California, Los Angeles (1)
China (6) · United States (3) · South Korea (2) · Brazil (1) · Canada (1) · Denmark (1) · Indonesia (1) · Italy (1) · Netherlands (1) · Nigeria (1) · Poland (1) · Singapore (1) · Spain (1)
Michael R Bristow, MD PhD (2) · B. Rensing, MD, PhD (1) · Ewa Nowalany-Kozielska, MD PhD Associate Professor (1) · Jun Pu, MD,PhD (1) · Kamilu M Karaye, PhD (1) · Marie-Annick Clavel, PhD (1) · Nan Bai, MD (1) · Serafino Fazio, MD (1) · Tamara B Horwich, MD (1) · Vitor E. E. Rosa, MD, PhD (1) · Yongwhi Park, MD., PhD. (1) · Young-Hoon Jeong, MD.,PhD. (1)
PMID 22041323, PMID 25637602, PMID 25858003, PMID 26482376, PMID 27056772, PMID 27825334, PMID 28132924, PMID 28138556, PMID 29142025, PMID 29311992, PMID 29440218, PMID 29932506, PMID 31074220, PMID 31370954, PMID 32470515, PMID 33032710, PMID 33087055, PMID 33397290, PMID 37656413, PMID 37732786, PMID 39291483, PMID 40052260, PMID 41730521
2023 (1), K23HL085097 (1), R01HL048013 (1)