253 completed, 123 unknown, 49 recruiting, 16 not yet recruiting. 173 Not applicable, 42 Phase 4, 36 Phase 3, 28 Phase 2, 1 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Right Heart and Lung Blood Flow During Exercise (RIGHT-NET 2.0) Right Ventricular Dysfunction, Cardiopulmonary Diseases | Not yet recruiting | IRCCS SYNLAB SDN | 2000 | 2027-01-01 | 2026-10-01 | |
| Assessment of Intelligent Algorithms for Detection, Diagnosis and Risk Stratification of Tumors of the Kidney and Prostate Medical Reading, AI assisted Medical reading - Kidney Cancers, Prostate Cancer | Not yet recruiting | Aristotle University Of Thessaloniki | 50 | 2026-10-15 | 2026-10-22 | |
| Dynamic Postoperative Trends for Early Detection of Complications After Gastrointestinal Surgery blood sampling - Oncologic Disease, Urgent Surgery | Not yet recruiting | Azienda Ospedaliero Universitaria Maggiore della Carita | 1500 | 2026-09-01 | 2026-04-03 | |
| Neurolyser XR for the Treatment of Sacroiliitis Patients treated with high intensity focused ultrasound - Sacroiliitis, Low Back Pain | Not applicable | Not yet recruiting | Federico II University | 30 | 2026-07-01 | 2026-06-16 |
| Circulating Tumor DNA Dynamics to Optimize Neoadjuvant Therapy in HER2-Positive and Triple-Negative Breast Cancer Breast Cancer, Triple Negative Breast Cancer (TNBC) | Not yet recruiting | Federico II University | 186 | 2026-07-01 | 2026-06-23 | |
| The Impact of Postbiotic Supplementation on Tolerability and Physiological/Metabolic Parameters Postbiotic Supplement, Placebo - Gastrointestinal Health | Not applicable | Active not recruiting | Federico II University | 22 | 2026-06-22 | 2026-10-23 |
| Shared Decision Making for Patients With HER2-negative Metastatic Breast Cancer (SDM-01) Shared Decision Making (SDM) Support Program - Breast Cancer, HER2 Negative Breast Cancer | Not applicable | Not yet recruiting | Federico II University | 120 | 2026-06-01 | 2026-05-11 |
| Effects of a Sugar-Based Synbiotic Product on Cardiometabolic and Intestinal Health (SUGAR-SYN BC3O) Sugar-Based Synbiotic Product, Inulin-Containing Sugar Product - Overweight Adults | Not applicable | Enrolling by invitation | Federico II University | 20 | 2026-05-04 | 2026-09-08 |
| TRacheostomy in DElphi for iNTensive Care' (TRiDENT) Delphi Consensus Process - Delphi Process, Delphi Study | Not yet recruiting | Universita degli Studi di Genova | 40 | 2026-05-01 | 2026-05-04 | |
| Validation of the Italian SCHFI v.8 and the CC-SCHFI v.3 Administration of the Italian version of the SCHFI and the CC-SCHFI, plus other self-reported ouctome measures - Heart Failure | Not yet recruiting | Centro Cardiologico Monzino | 1000 | 2026-05-01 | 2026-05-27 | |
| Tinnitus and Treatment With umPEA-LUT PEA-LUT 2 sachet day, Placebo, umPEALUT + Rutin + 5 hTp - Tinnitus, Neuroinflammation | Not applicable | Not yet recruiting | University of Campania Luigi Vanvitelli | 100 | 2026-04-20 | 2026-02-06 |
| Fall Prevention in Older Adults in an Italian Cohort Khymeia - Fall Risk, Fall Prevention, Fall Risk | Not yet recruiting | Federico II University | 50 | 2026-02-20 | 2026-02-27 | |
| Use of Continuous Glucose Monitoring to Evaluate Postprandial Response to Raw Cornstarch Supplementation in Adult Glycogen Storage Disease Type I Glycogen Storage Disease Type I | Recruiting | Federico II University | 8 | 2026-02-05 | 2026-06-12 | |
| Inhibition of Late Sodium Current (INa) to Prevent Coronary MICROvascular Dysfunction in Patients Presenting With ST-Elevation Myocardial Infarction and Multivessel Disease: INaMICRON Study Ranolazine - STEMI (ST Elevation MI) | Phase 2 / Phase 3 | Recruiting | Federico II University | 100 | 2026-02-01 | 2026-03-11 |
| Evaluation of the Tolerance of a New Formula Based on Hydrolyzed Rice Proteins in Children With Cow's Milk Allergy Rice formula (New formula based on hydrolysed rice proteins), Placebo formula - IgE-Mediated Cow Milk Allergy | Not applicable | Recruiting | Health and Happiness Research Limited | 29 | 2026-01-23 | 2026-09-09 |
| Evaluation of Real-World Data on Ropeginterferon Alfa-2b in Patients With Polycythemia Vera: Insights From a Multicenter Study Ropeginterferon alfa-2b (BESREMi®) - Polycytemia Vera | Not yet recruiting | Federico II University | 150 | 2026-01-10 | 2025-12-15 | |
| Autoimmune Hyperthyroidism in Prepubertal Children restrospective observational study - Autoimmune Hyperthyroidism, Children | Enrolling by invitation | IRCCS Ospedale San Raffaele | 100 | 2026-01-01 | 2026-04-22 | |
| Incidence of Intrauterine Adhesions After Myomectomy With Intrauterine Anti-Adhesion Gel Women will receive the application of an anti-adhesion gel at the end of the myomectomy procedure - Myoma;Uterus, Adhesion; Uterus, Internal | Not applicable | Not yet recruiting | Federico II University | 62 | 2025-12-09 | 2025-12-12 |
| Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Bempedoic Acid in Italy Bempedoic acid - Hypercholesterolemia | Recruiting | Federico II University | 1500 | 2025-11-04 | 2026-01-29 | |
| GLP1-RAs Effects on Inflammatory and Endothelial Biomarkers in T2DM semaglutide, Standard Treatment (Guideline-Based) - T2DM (Type 2 Diabetes Mellitus) | Phase 4 | Recruiting | Federico II University | 80 | 2025-09-08 | 2026-01-02 |
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Obesity (22) · Heart Failure (19) · Milk Hypersensitivity (19) · Premature Birth (17) · Acute Coronary Syndrome (12) · Diabetes Mellitus, Type 2 (11) · Metabolic Syndrome (10) · Dwarfism, Pituitary (9) · Breast Neoplasms (8) · Diabetes Mellitus, Type 1 (8) · Hypersensitivity (8) · Overweight (8) · Coronary Artery Disease (7) · Food Hypersensitivity (7) · Insulin Resistance (7)
Diet, Mediterranean (7) · Growth Hormone (6) · Cerclage, Cervical (4) · Exercise (4) · Human Growth Hormone (4) · Data Collection (3) · Dietary Supplements (3) · Hyaluronic Acid (3) · Ranibizumab (3) · Synbiotics (3) · lanreotide (3) · policosanol (3) · Berberine (2) · Blood Specimen Collection (2) · Butyrates (2)
Italy (398) · Spain (6) · Germany (5) · United Kingdom (5) · Belgium (4) · Netherlands (4) · United States (3) · Canada (2) · Greece (2) · Hungary (2) · Norway (2) · Russia (2) · Croatia (1) · Egypt (1) · France (1)
Gilda Cennamo (15) · Bruno Trimarco, MD (6) · Annamaria Colao, MD, PhD (5) · Giovanni Esposito, MD, PhD (5) · Alessandro Filla, MD (4) · Roberto Berni Canani, MD, PhD (4) · Annamaria AL Colao, Prof. (3) · Annamaria Colao, MD (3) · Serafino Fazio, MD (3) · Alfredo Guarino, MD (2) · Amanda Roman, MD (2) · Annamaria Colao (2) · Annamaria Colao, Prof (2)
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2025 (2), 2009 (1), 2016 (1), 2017 (1)