2442 completed. 2442 Phase 3, 295 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2442 | Completed 2442 |
| Phase 2 | 295 | Completed 295 |
Follow Vascular Diseases: new trials by email Literature Review of Vascular Diseases trials Research Report on Vascular Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Heparin for RAO Post-Transradial Angiography in AIS Heparin - Therapeutic dosage, Saline (0.9% NaCl) - Acute Ischemic Stroke | Phase 3 | Completed | Xiang Luo | 440 | 2025-08-04 | 2026-03-24 |
| Sildinafil in Pulmonary Hypertension-Rheumatic Chronic Valvular Disease(RCT) Sildenafil 25 MG, Placebo - Pulmonary Hypertension, Rheumatic Valvular Heart Disease | Phase 2 / Phase 3 | Completed | Sindh Institute of Cardiovascular Diseases | 100 | 2025-08-01 | 2026-09-24 |
| A Clinical Study of SHR-2004 Injection in Preventing Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty SHR-2004 injection, Enoxaparin sodium injection, Enoxaparin sodium injection placebo - Prevention of Arterial and Venous Thrombosis | Phase 3 | Completed | Beijing Suncadia Pharmaceuticals Co., Ltd | 1165 | 2025-03-16 | 2026-08-28 |
| A Phase III Study to Efficacy and Safety of DWC202405/DWC202313 and DWC202314 in Patients With Hypertension DWC202405, DWC202405, DWC202314, DWC202405, DWC202314P - Essential Hypertension | Phase 3 | Completed | Daewoong Pharmaceutical Co. LTD. | 198 | 2025-02-24 | 2026-03-19 |
| Efficacy and Safety of DWC202404 and DWC202314 in Patients With Hypertension DWC202404, DWC202314, DWC202404, DWC202314P - Hypertension, Essential Hypertension | Phase 3 | Completed | Daewoong Pharmaceutical Co. LTD. | 192 | 2025-01-20 | 2026-05-08 |
| Dexmedetomidine in Attenuation of Haemodynamic Response to Laryngoscopy in Controlled Hypertensive Patients Dexmedetomidine, Normal Saline - Hypertension, Hemodynamic Response | Phase 3 | Completed | Sindh Institute of Urology and Transplantation | 70 | 2025-01-01 | 2026-04-29 |
| Efficacy and Safety of Early Combined Therapy With PCSK9 Inhibitors and Statins in Acute Ischemic Stroke PCSK9 inhibitors combined with atorvastatin/rosuvastatin, Atorvastatin/Rosuvastatin - Acute Ischemic Stroke | Phase 2 / Phase 3 | Completed | Xiang Luo | 429 | 2024-11-29 | 2026-06-09 |
| Assess Sacubitril/Allisartan and Amlodipine in Patients With Essential Hypertension Uncontrolled With Sacubitril/Allisartan Experimental: Sacubitril/Allisartan and Amlodipine Group, Active Comparator: Sacubitril/Allisartan Group - Essential Hypertension | Phase 3 | Completed | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 346 | 2024-11-23 | 2026-07-15 |
| What Causes Low Blood Pressure After Anesthesia in Older Adults Having Non-Heart Surgery ? Standard General Anesthesia Induction Using Propofol, Fentanyl and Midazolam, Blood Pressure Continous Monitoring, syrnge pump for the anesthesia agent, and vasoconstrictor drug - Geriatric, General Anesthesia Induced Hypotension | Phase 3 | Completed | Universitas Indonesia | 220 | 2024-09-01 | 2025-06-13 |
| "The Effect of Trimetazidine on the Clinical Outcome of Acute Ischemic Stroke Patients" Trimetazidine - Acute Ischemic Stroke | Phase 3 | Completed | Ain Shams University | 60 | 2024-09-01 | 2025-09-08 |
| Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-C ) Emergency Stroke Unit based on 0.23-T MRI, Standard stroke unit adherent to guidelines - Ischemic Stroke, Acute | Phase 3 | Completed | Beijing Tiantan Hospital | 1622 | 2024-08-08 | 2025-08-22 |
| Open-Label Safety, PK, and Efficacy Trial of Sebetralstat (KVD900) in Pediatric Patients (Ages 2-11) With HAE Type I or II KVD900 150 mg, KVD900 300 mg, KVD900 600 mg - Hereditary Angioedema | Phase 3 | Completed | KalVista Pharmaceuticals, Ltd. | 36 | 2024-08-01 | 2026-08-05 |
| Y-3 for Injection in the Treatment of Acute Ischemic Stroke Y-3 for injection, Placebo control group - Acute Ischemic Stroke | Phase 3 | Completed | Beijing Tiantan Hospital | 998 | 2024-07-24 | 2026-07-07 |
| Dimolegin® (60 mg) Given Once Daily in Patients Undergoing Total Hip or Knee Replacement Compared to Enoxaparin Sodium enoxaparin, Dimolegin, Dimolegin placebo - Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee | Phase 3 | Completed | Avexima Diol LLC | 215 | 2024-07-22 | 2026-01-16 |
| To Compare Post-op Analgesic Effectiveness of Ropivicaine+Dexamethasone and Ropivacane+Dexmetomidine in TAP Block in Stoma Reversal Under GA in Terms of Duration of Analgesia. TAP Block with Ropivacaine+Dexamethasone, TAP Block with Ropivacaine+Dexmedetomidine - Post Operative Analgesia, Opioid Sparing Anaesthesia | Phase 2 / Phase 3 | Completed | Sahiwal medical college sahiwal | 86 | 2024-07-22 | 2026-01-26 |
| Nifedipine Extended-Release in Patients With Mild or Moderate Hypertension Treatment with Nifedipine 30 mg Extended-Release (Richmond), Comparator Nifedipine 30 mg Extended-Release - High Blood Pressure (& [Essential Hypertension]) | Phase 3 | Completed | Laboratorios Richmond S.A.C.I.F. | 50 | 2024-07-09 | 2026-08-13 |
| Evaluate the Neurological Effects of EryDex on Subjects With A-T Dexamethasone sodium phosphate, Placebo - Ataxia Telangiectasia | Phase 3 | Completed | Quince Therapeutics S.p.A. | 105 | 2024-06-24 | 2026-04-30 |
| Comparison of General Anesthesia Hemodynamics Between R and P in Patients Undergoing Laparoscopic Hepatectomy propofol, Remimazolam - Hypotension During Surgery | Phase 3 | Completed | Sun Yat-sen University | 88 | 2024-06-20 | 2024-12-03 |
| Ringer Acetate Based Modified Del Nido Cardioplegia Solution Versus HTK Solution Cardioplegia Solution in Cardiac Surgery Ringer acetate based Del Nido cardioplegia, HTK - Cardiac Ischemia | Phase 3 | Completed | Assiut University | 124 | 2024-06-01 | 2025-12-22 |
| Melatonin for Pulmonary Hypertension in Full Term Neonates Melatonin, Placebo - Neonatal Diseases and Abnormalities, Neonatal Mortality | Phase 3 | Completed | Ain Shams University | 40 | 2024-05-15 | 2025-07-10 |
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Hypertension (501) · Stroke (220) · Coronary Artery Disease (205) · Multiple Myeloma (197) · Cardiovascular Diseases (159) · Myocardial Infarction (150) · Coronary Disease (135) · Heart Diseases (119) · Essential Hypertension (105) · Ischemic Stroke (103) · Myocardial Ischemia (103) · Atherosclerosis (99) · Acute Coronary Syndrome (82) · Venous Thromboembolism (80) · Venous Thrombosis (77)
Cardiovascular Diseases (2283) · Pathological Conditions, Signs and Symptoms (658) · Heart Diseases (538) · Nervous System Diseases (485) · Pathologic Processes (480) · Myocardial Ischemia (459) · Central Nervous System Diseases (441) · Brain Diseases (436) · Cerebrovascular Disorders (403) · Arterial Occlusive Diseases (362) · Arteriosclerosis (349) · Immune System Diseases (312) · Embolism and Thrombosis (277) · Hemic and Lymphatic Diseases (275)
Amlodipine (96) · Dexamethasone (86) · Clopidogrel (76) · Hydrochlorothiazide (72) · Aspirin (62) · Valsartan (57) · Enoxaparin (49) · Rivaroxaban (48) · Bortezomib (47) · aliskiren (43) · Telmisartan (42) · Lenalidomide (41) · Warfarin (40) · Rosuvastatin Calcium (36) · Ticagrelor (36)
Novartis (84) · Boehringer Ingelheim (70) · National Heart, Lung, and Blood Institute (NHLBI) (69) · Novartis Pharmaceuticals (54) · Bayer (44) · Sanofi (40) · AstraZeneca (36) · Assistance Publique - Hôpitaux de Paris (35) · Takeda (35) · Boston Scientific Corporation (31) · GlaxoSmithKline (28) · Organon and Co (26) · Shire (24) · Cordis US Corp. (18) · Amgen (17)
United States (891) · Germany (458) · Canada (419) · France (375) · Italy (334) · United Kingdom (309) · Spain (306) · Poland (257) · Netherlands (250) · Belgium (245) · Australia (232) · South Korea (227) · China (224) · Czechia (205) · Russia (199)
PMID 35224730, PMID 36326435, PMID 33089502, PMID 24081972, PMID 27160944, PMID 35570249, PMID 37565307, PMID 40163217, PMID 18783301, PMID 19463432, PMID 20129555, PMID 20818886, PMID 22017936, PMID 22115661, PMID 23232250, PMID 23312695, PMID 24746650, PMID 27162632, PMID 31221778, PMID 31867054, PMID 32609313, PMID 33337539, PMID 34022170, PMID 34289038, PMID 34932836, PMID 35916348, PMID 38682786, PMID 41114449, PMID 17296825, PMID 18190818, PMID 18806012, PMID 20136164, PMID 20573750, PMID 21740078, PMID 21899409, PMID 22371186, PMID 22429800, PMID 22496083, PMID 22689675, PMID 22709460, PMID 23548529, PMID 23661689, PMID 2375765, PMID 23878046, PMID 24712435, PMID 25614280, PMID 25698905, PMID 25940520, PMID 27206567, PMID 27263466
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