5 completed, 4 unknown, 2 terminated, 1 recruiting. 13 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 13 | Completed 5, Unknown 4, Terminated 2, Recruiting 1, Withdrawn 1 |
Follow Total Knee Replacement: new trials by email Literature Review of Total Knee Replacement trials Research Report on Total Knee Replacement
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Genicular and Anterior Femoral Cutaneous Nerve Blocks for Total Knee Arthroplasty Bupivacaine Injection, Dexamethasone injection, Fentanyl - Total Knee Replacement, Genicular Nerve Block | Phase 4 | Completed | Hospital for Special Surgery, New York | 244 | 2023-06-07 | 2025-10-08 |
| Tapentadol vs Tramadol in Total Knee Arthroplasty Tapentadol, Tramadol - Total Knee Replacement, Post-operative Pain | Phase 4 | Unknown | University of Thessaly | 96 | 2023-05-01 | 2024-05-14 |
| A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation Dexamethasone Sodium Phosphate 4 mg/ml intravenous, Dexamethasone Sodium Phosphate 4 mg/ml intra-articular - Total Knee Replacement | Phase 4 | Recruiting | Christian Candrian | 159 | 2020-07-01 | 2026-09-11 |
| Antibiotic Elution in Total Knee Arthroplasty hand mixed vancomycin, hand mixed tobramycin, pre-mixed tobramycin - Total Knee Replacement | Phase 4 | Completed | Washington University School of Medicine | 60 | 2019-01-28 | 2020-11-02 |
| Effects of Combined Topical and Systemic Steroid Administrations on Better Early Postoperative Pain Management in Total Knee Arthroplasty Dexamethasone, Triamcinolone, Placebos - Total Knee Replacement | Phase 4 | Unknown | The University of Hong Kong | 180 | 2018-04-26 | 2019-04-03 |
| Predicting, Understanding and Speeding Recovery After TKA Gabapentin, Placebo - Pain, Total Knee Replacement | Phase 4 | Terminated | Wake Forest University Health Sciences | 350 | 2016-06-02 | 2025-08-15 |
| Prophecy Guide Outcomes in Total Knee Replacement Surgery Prophecy Technique, Navigation System - Osteoarthritis of the Knee, Total Knee Replacement | Phase 4 | Unknown | Global Orthopaedic Technology | 188 | 2010-08-01 | 2010-07-29 |
| The Analgesic Efficacy of Local Anaesthetic Wound Infiltration Versus Intrathecal Morphine for Total Knee Replacement Levobupivacaine, Intrathecal morphine - Total Knee Replacement | Phase 4 | Unknown | Cork University Hospital | 42 | 2010-08-01 | 2011-03-10 |
| ChloraPrep Versus Betadine for Elective Knee Replacement Surgery Swab area with Betadine, Swab area with ChloraPrep - Arthroplasty, Knee Replacement, Replacement, Total Knee | Phase 4 | Terminated | Central DuPage Hospital | 55 | 2009-11-01 | 2013-04-16 |
| The Effects of Arixtra on Wound Drainage Following Total Joint Arthroplasty Fondaparinux Sodium (Arixtra) - Total Knee Replacement | Phase 4 | Completed | Paul Di Cesare,MD | 114 | 2009-06-01 | 2017-05-15 |
| Comparative Pain Control Between 0.2 or 0.3 Spinal Morphine and 0.25 or 0.5 % Bupivacaine for FNB After TKA morphine and bupivacaine, spinal morphine and marcaine - Post Operative Pain, Total Knee Replacement | Phase 4 | Completed | Mahidol University | 160 | 2008-10-01 | 2009-09-29 |
| Total Knee Arthroplasty Outcome Study MIS™ Minimally Invasive Solutions™ TKA System - Total Knee Replacement | Phase 4 | Withdrawn | University of Florida | 2005-08-01 | 2012-05-02 | |
| Patellar Resurfacing Versus Patellar Retention in Total Knee Arthroplasty - A Randomized Clinical Trial Patellar Replacement Prosthesis, Profix TKR with Patellar Retention - Total Knee Replacement | Phase 4 | Completed | University of Alberta | 38 | 1996-09-01 | 2021-07-27 |
Pain, Postoperative (2) · Chronic Pain (1) · Osteoarthritis, Knee (1) · Pain (1)
Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Pain (2) · Pathologic Processes (2) · Postoperative Complications (2) · Arthritis (1) · Joint Diseases (1) · Musculoskeletal Diseases (1) · Osteoarthritis (1) · Rheumatic Diseases (1)
Bupivacaine (2) · Calcium Dobesilate (1) · Dexamethasone (1) · Excipients (1) · Fentanyl (1) · Fondaparinux (1) · Gabapentin (1) · Levobupivacaine (1) · Mepivacaine (1) · Morphine (1) · Povidone-Iodine (1) · Surgical Navigation Systems (1) · Tapentadol (1) · Tobramycin (1) · Tramadol (1)
Central DuPage Hospital (1) · Christian Candrian (1) · Cork University Hospital (1) · Global Orthopaedic Technology (1) · Hospital for Special Surgery, New York (1) · Mahidol University (1) · Paul Di Cesare,MD (1) · The University of Hong Kong (1) · University of Alberta (1) · University of Florida (1) · University of Thessaly (1) · Wake Forest University Health Sciences (1) · Washington University School of Medicine (1)
United States (5) · Australia (1) · Canada (1) · Greece (1) · Hong Kong (1) · Ireland (1) · Switzerland (1) · Thailand (1)
Charles Lawrie, MD (1) · Christian Candrian, MD, Prof. (1) · Denise M McCarthy, MB FCARSCI (1) · Eleni Arnaoutolglou, MD, PhD (1) · Hugh English (1) · James C Eisenach, MD (1) · Jiabin Liu, MD/PhD (1) · Metaxia Bareka, MD, PhD (1) · Paul E. DiCesare, MD (1) · Richard G. Vlasak, M.D. (1) · Scott Sporer, MD (1) · Thitima Chinachoti, MD (1)
PMID 22676495, PMID 29357330, PMID 30640244, PMID 34261807, PMID 34308957
P01GM113852 (1)