76 completed, 29 unknown, 15 terminated, 6 recruiting. 53 Not applicable, 36 Phase 4, 24 Phase 3, 15 Phase 2, 7 Phase 1.
Follow this drug Literature Review of Povidone-Iodine trials Research Report on Povidone-Iodine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Betadine Vaginal Cleansing Before Cesarean Section to Reduce Postoperative Infectious Morbidity Povidone-iodine 5% solution - Cesarean Section, Surgical Site Infection | Not applicable | Not yet recruiting | Mohamed Mousa Mohamed Mousa | 600 | 2027-05-01 | 2026-07-20 |
| Sequential PVP-I and FV fluoride varnish, 2.5%, topical fluoride, 2.1%, Povidone Iodine Topical - Dental Caries | Not yet recruiting | Advantage Silver Dental Arrest, LLC | 393 | 2026-09-01 | 2026-07-06 | |
| Povidone Iodine for Caries Prevention Povidone Iodine 5% Soln,Top,Kit, Probiotics, Placebo - Dental Caries | Phase 3 | Not yet recruiting | Jeffrey A. Banas | 174 | 2026-08-03 | 2026-08-03 |
| Intra-Sinus Povidone-Iodine and Budesonide After Endoscopic Sinus Surgery for Chronic Rhinosinusitis Povidone-Iodine and Budesonide Gel-Forming Suspension, Placebo Gel-Forming Suspension - Chronic Rhinosinusitis (CRS) | Phase 3 | Not yet recruiting | Amin Javer | 180 | 2026-03-30 | 2026-02-03 |
| Betadine vs Sterile Water for Periurethral Preparation Povidone-Iodine, Sterile water - Catherization, Urinary Tract Infection Bacterial | Phase 4 | Recruiting | University of Louisville | 148 | 2025-06-30 | 2026-05-04 |
| Post-incision Antimicrobial Wash vs C. Acnes in Shoulder Arthroplasty Povidone-Iodine, Hydrogen Peroxide, Xperience Antimicrobial Wash - Shoulder Arthroplasty, Positive C. Acnes Culture | Not applicable | Recruiting | Henry Ford Health System | 150 | 2025-05-05 | 2026-09-18 |
| Pseudomonas Aeruginosa Injection Combined With Polyvinylpyrrolidone-Iodine in Immediate Breast Reconstruction Surgery With Implants Pseudomonas aeruginosa, Povidone-Iodine - Postoperative Seroma Rate, Drainage Tube Removal Time, and Capsular Contracture Rate, Seroma Following Procedure | Not applicable | Enrolling by invitation | Jianyi Li | 100 | 2025-04-16 | 2026-03-10 |
| Essential Oil Mouthwash - Oral Hygiene Essential oil mouthwash, Chlorhexidine gluconate alcohol-free mouthwash, Povidone-iodine alcohol-free mouthwash - Oral Hygiene, Oral Health, Dental Plaque | Not applicable | Completed | China Medical University, Taiwan | 150 | 2025-04-12 | 2026-10-21 |
| Analyzing the Effect of Disinfection Additives on the Linear Dimensional Stability of Dental Alginate Impressions: A Quasi-Experimental Comparative Study Alginate mixed with distilled water, 0.2% Chlorhexidine + Alginate, 1% Chitosan + Alginate - Dimensional Changes | Not applicable | Not yet recruiting | Altamash Institute of Dental Medicine | 96 | 2025-04-01 | 2025-03-28 |
| Povidone-Iodine Versus Chlorhexidine in Surgical Wound Care Povidone-Iodine, Chlorhexidine - Wound | Not applicable | Completed | University of Jaén | 107 | 2025-01-07 | 2025-04-22 |
| Different Perineal Preparations Before Vaginal Birth to Maternal/Neonatal Infections and Cost Effectiveness Povidone-Iodine (PVP-I), Water - Perineal Infection, Maternal Infections Affecting Fetus or Newborn | Not applicable | Completed | Tzu-Ying Huang | 320 | 2024-11-30 | 2025-08-15 |
| Evaluation of the Decolonization Rate and Acceptance of a Complete Nasal Decolonization Kit With Povidone Iodine for MRSA Patients Betadine - MRSA | Phase 2 | Terminated | Nantes University Hospital | 1 | 2024-11-21 | 2025-12-23 |
| Nasal Iodine Swab Versus Oral Antibiotic to Prevent Surgical Site Infection After Undergoing Mohs Micrographic Surgery Povidone-Iodine Swabs, Staphylococcus nasal swab, Antibiotic - Skin Cancer, Skin Cancer Face | Not applicable | Withdrawn | Mayo Clinic | 2024-09-01 | 2024-11-25 | |
| Povidone Iodine Nasal Application to Prevent Intraoperative Spread of SARS-CoV-2 Povidone Iodine 5% Soln,Top,Kit - SARS-CoV-2 Acute Respiratory Disease | Phase 4 | Withdrawn | University of Iowa | 2024-07-03 | 2023-11-18 | |
| Diluted Aqueous Povidone-Iodine Compared to Saline to Decrease Surgical Site Infections Povidone-Iodine, Normal Saline - Surgical Site Infection | Phase 3 | Recruiting | Loma Linda University | 1100 | 2024-06-03 | 2025-11-19 |
| Infection Prophylaxis in Total Joint Replacement Chlorhexidine Gluconate, Vancomycin Hydrochloride, Povidone-Iodine - Periprosthetic Joint Infection | Phase 3 | Recruiting | Hamilton Health Sciences Corporation | 21006 | 2024-05-07 | 2026-05-22 |
| Nasal Antisepsis for C. Auris Prevention Povidone Iodine Topical - Candida Auris Infection, Colonization, Asymptomatic | Phase 4 | Recruiting | Mary K Hayden | 120 | 2024-01-29 | 2025-10-15 |
| SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty Povidone-Iodine, SURGX Wound Gel - Surgery, Surgical Site Infection | Phase 4 | Completed | St. Louis University | 60 | 2023-06-26 | 2024-12-10 |
| Oro-nasal Decontamination to Prevent Ventilator-associated Pneumonia Povidone-Iodine, Saline spray - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Completed | Menoufia University | 78 | 2023-06-24 | 2023-11-27 |
| Efficacy of Pyodine Soaked Gelfoam vs Single Topical Application of Clotrimazole in Otomycosis Treatment Clotrimazole Cream, Povidone-Iodine - Otomycosis | Phase 1 | Completed | Rawalpindi Medical College | 90 | 2023-06-16 | 2024-04-01 |
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Surgical Wound Infection (24) · COVID-19 (12) · Infections (12) · Wound Infection (7) · Wounds and Injuries (5) · Pleural Effusion, Malignant (4) · Urinary Tract Infections (4) · Bacteremia (3) · Dental Caries (3) · Endometritis (3) · Sepsis (3) · Catheter-Related Infections (2) · Coronavirus Infections (2) · Cross Infection (2) · Dental Plaque (2)
Assiut University (5) · Mashhad University of Medical Sciences (3) · Seoul National University Hospital (3) · St. Paul's Hospital, Canada (3) · Ain Shams Maternity Hospital (2) · Ain Shams University (2) · Cairo University (2) · Federal Teaching Hospital Abakaliki (2) · King Abdulaziz University (2) · Poitiers University Hospital (2) · Post Graduate Institute of Medical Education and Research, Chandigarh (2) · Universidad de Guanajuato (2) · University of California, Los Angeles (2) · University of Colorado, Denver (2) · University of Miami (2)
United States (47) · Egypt (12) · Canada (8) · France (5) · Iran (4) · Israel (4) · Nigeria (4) · India (3) · South Korea (3) · Spain (3) · Taiwan (3) · Thailand (3) · Brazil (2) · Indonesia (2) · Mexico (2)
Alejandro E Macias, M. D. (2) · David A Kaufman, MD (2) · Sherwin J. Isenberg, M.D. (2) · Adisak Trinavarat, MD (1) · Afroze Khan, MBBS MRCS (1) · Aida Najafian (1) · Alan I. So, MD, FRCSC (1) · Alejandro Mira, PhD (1) · Ali Bazzi, MSc (1) · Alison Harris, MD, FRCPC (1) · Allen Rowley, MD, FRCPC (1) · Alparslan Dilsiz, Prof. (1) · Amin Javer, M.D. (1)
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8UL1TR000114-02 (1)