54 completed, 11 unknown, 7 terminated, 2 recruiting. 18 Phase 3, 15 Phase 4, 13 Not applicable, 12 Phase 1, 12 Phase 2.
Follow Tobramycin: new trials by email Literature Review of Tobramycin trials Research Report on Tobramycin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Comparative Study Between Preservative With Benzalkonium Chloride vs Preservative Free Eye Drops on the Ocular Surface Dexamethasone, tobramycin, netilimicin - Ocular Surface Disease, Dry Eye Syndromes | Phase 4 | Unknown | Kasr El Aini Hospital | 60 | 2024-01-10 | 2024-05-08 |
| Vancomycin and Tobramycin Powder Use in Acute Open Fractures Cephalosporin or clindamycin/vancomycin antibiotics.., Vancomycin and Tobramycin antibiotics. - Infections | Early Phase 1 | Completed | University of Utah | 10 | 2023-03-27 | 2024-12-20 |
| Antibiotic Loaded Cement After TKA total knee arthroplasty, Tobramycin, Gentamicin - Total Knee Arthoplasty | Phase 3 | Completed | Rothman Institute Orthopaedics | 50 | 2022-06-20 | 2024-04-30 |
| Patient Satisfaction and Long-term Safety of Intravesical Aminoglycoside Instillations in UTI Prevention Intravesical aminoglycoside instillations - Urinary Tract Infections, Recurrent Urinary Tract Infection | Completed | Leiden University Medical Center | 44 | 2022-04-20 | 2023-03-08 | |
| Antibiotic Impregnated Bone Graft to Reduce Infection in Hip Replacement. Vancomycin + Tobramycin, Saline - Arthroplasty, Replacement, Hip, Osteoarthritis, Hip | Phase 2 | Recruiting | University Hospital, Linkoeping | 1100 | 2022-04-01 | 2026-07-10 |
| Effect of Various Treatment Modalities on Dendritic Vial Ulcer Acyclovir, Tobramycin, Fluorometholone - Corneal Ulcer | Unknown | Sohag University | 40 | 2022-03-18 | 2022-04-06 | |
| Tobramycin Injection to Prevent Infection in Open Fractures Tobramycin Injection - Wound Infection, Fractures, Open | Phase 3 | Completed | Massachusetts General Hospital | 600 | 2022-01-10 | 2026-09-16 |
| Abbreviated Protocol for Two-Stage Exchange VT-X7 Treatment System with Tobramycin Sulfate, Standard of Care, Two-stage exchange arthroplasty - Prosthetic Joint Infection | Phase 2 | Completed | Osteal Therapeutics, Inc. | 76 | 2021-11-01 | 2026-10-15 |
| Acute Application of Antibiotic Powder in Open Fracture Wounds Vancomycin, Tobramycin - Fractures, Open, Wounds and Injuries--Infections | Phase 4 | Completed | University of Colorado, Denver | 20 | 2021-06-14 | 2026-03-06 |
| Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT 2 Standard of care, Vancomycin and Tobramycin - Post Operative Surgical Site Infection | Phase 3 | Recruiting | Major Extremity Trauma Research Consortium | 600 | 2021-05-07 | 2026-07-22 |
| To Study Efficacy and Safety of Tobradex Eye Drop Suspension vs Tobramycin/Dexamethasone Ophthalmic Suspension Tobramycin/dexamethasone opthalmic solution, Tobradex Opthalmic Solution - Blepharo Conjunctivitis | Early Phase 1 | Unknown | Sutphin Drugs | 5000 | 2019-06-15 | 2019-06-05 |
| DPI-Tobra-Kind Cyclops® in Children With Cystic Fibrosis Tobramycin - Cystic Fibrosis | Phase 1 / Phase 2 | Unknown | University Medical Center Groningen | 10 | 2019-05-29 | 2021-10-01 |
| Tobramycin Administered at the Beginning of Dialysis Tobramycin - Renal Dialysis, Renal Failure, Chronic | Phase 1 | Completed | Maisonneuve-Rosemont Hospital | 11 | 2019-01-31 | 2021-02-26 |
| Antibiotic Elution in Total Knee Arthroplasty hand mixed vancomycin, hand mixed tobramycin, pre-mixed tobramycin - Total Knee Replacement | Phase 4 | Completed | Washington University School of Medicine | 60 | 2019-01-28 | 2020-11-02 |
| Safety and Efficacy in Patients Treated for Hip or Knee PJI With Vancomycin and Tobramycin Joint Irrigation vancomycin hydrochloride and tobramycin sulfate - Prosthetic Joint Infection | Phase 2 | Completed | Osteal Therapeutics, Inc. | 15 | 2018-10-26 | 2022-01-11 |
| Topical Antibiotics in Chronic Rhinosinusitis Mupirocin, Tobramycin, Levofloxacin - Chronic Rhinosinusitis (Diagnosis) | Phase 1 / Phase 2 | Completed | Mayo Clinic | 19 | 2018-09-26 | 2022-04-20 |
| Study for Antibiotic Impregnated Calcium Sulfate Beads as Prophylaxis for Surgical Site Infection Stimulan Rapid Cure, Vancomycin, Tobramycin - Surgical Site Infection | Phase 4 | Unknown | McMaster University | 60 | 2018-07-16 | 2018-07-19 |
| Evaluation of Short Antibiotic Combination Courses Followed by Aerosols in Cystic Fibrosis Tobi Inhalant Product, Nebcin - Cystic Fibrosis | Phase 3 | Terminated | University Hospital, Lille | 23 | 2017-06-13 | 2021-09-05 |
| Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients SDD Oral Paste, SDD Gastric Suspension, Intravenous Antibiotic - Critical Illness, Sepsis | Phase 3 | Completed | The George Institute | 20010 | 2017-05-01 | 2023-08-14 |
| Tobramycin Delivered by Nebulized Sonic Aerosol for Chronic Rhinosinusitis Treatment of Cystic Fibrosis Patients Tobramycin nebulized nasally, Physiologic serum nebulized nasally - Cystic Fibrosis, Rhinosinusitis | Phase 3 | Terminated | Virginie ESCABASSE | 86 | 2017-02-16 | 2023-02-15 |
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Cystic Fibrosis (21) · Infections (6) · Pseudomonas Infections (6) · Dry Eye Syndromes (4) · Bronchiectasis (3) · Cataract (3) · Conjunctivitis (3) · Fractures, Open (3) · Myopia (3) · Pneumonia, Ventilator-Associated (3) · Astigmatism (2) · Blepharitis (2) · Eye Infections (2) · Lung Diseases (2) · Renal Insufficiency, Chronic (2)
Bausch & Lomb Incorporated (4) · Alcon Research (3) · Novartis (3) · Sun Yat-sen University (3) · Chiesi Farmaceutici S.p.A. (2) · McMaster University (2) · Osteal Therapeutics, Inc. (2) · Seattle Children's Hospital (2) · University Medical Center Groningen (2) · Veroia General Hospital (2) · Allergan (1) · Centre Hospitalier Universitaire de Besancon (1) · Daniel Benjamin (1) · Erempharma (1) · FDA Office of Orphan Products Development (1)
United States (32) · France (8) · United Kingdom (8) · Canada (7) · Germany (6) · Netherlands (5) · China (3) · Spain (3) · Egypt (2) · Ireland (2) · Israel (2) · Italy (2) · Poland (2) · Singapore (2) · Ukraine (2)
Bryan Springer, MD (2) · Henryk Mazurek, Doctor (2) · Ajai Prakash (1) · Alan Bruce Montgomery (1) · Albert Y Wu, M.D., Ph.D. (1) · Anthony Gordon, MD FRCA (1) · Anthony R Carlini, MS (1) · Arun Aneja, MD, PhD (1) · Bonnie W. Ramsey (1) · Brian Cuthbertson, MD FRCA (1) · Charles Lawrie, MD (1) · Chi Hornik, PharmD (1) · Dan Z Reinstein, MD MA (1) · David R Lionberger, MD (1)
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2008 (1), 2014 (1), M01RR000037 (1), R01DK057755 (1), U01HL080310 (1)