69 completed, 9 recruiting, 7 terminated, 4 unknown. 95 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 95 | Completed 69, Recruiting 9, Terminated 7, Unknown 4, Withdrawn 4, Active not recruiting 1, Not yet recruiting 1 |
Follow Tobacco Use Disorder: new trials by email Literature Review of Tobacco Use Disorder trials Research Report on Tobacco Use Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder (SMARTTT 2.0) Among Persons With HIV: A Multi-site Hybrid Type 2 Effectiveness-implementation Trial nicotine patch, nicotine gum, nicotine lozenge, varenicline, bupropion, Multi-target Contingency Management, Teamlet booster - Tobacco Use Disorder/Cigarette Smoking, HIV | Phase 4 | Not yet recruiting | Yale University | 794 | 2027-09-30 | 2026-09-23 |
| Varenicline for Smoking Reduction in Veterans Not Ready To Quit Motivation-Phase Varenicline, Motivation-Phase Nicotine Mini-Lozenge, Cessation-Phase Combination Nicotine Replacement Therapy (NRT) - Veterans, Tobacco Use Disorder | Phase 4 | Recruiting | VA Office of Research and Development | 400 | 2026-08-17 | 2026-08-31 |
| Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study) Varenicline, Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation Sham - Nicotine Dependence, Transcranial Magnetic Stimulation | Phase 4 | Recruiting | Massachusetts General Hospital | 30 | 2026-07-02 | 2026-09-15 |
| C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker - Tobacco Dependence | Phase 4 | Active not recruiting | Johns Hopkins University | 30 | 2025-12-10 | 2026-07-06 |
| Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness Nicotine Replacement Therapy (NRT), Wellness Coaching - Tobacco Cessation, Tobacco Abstinence | Phase 4 | Recruiting | University of California, San Francisco | 150 | 2025-11-14 | 2025-11-21 |
| tDCS Plus Varenicline for Smoking Cessation Active Transcranial Direct Current Stimulation (tDCS), Varenicline 1mg BID, Sham Transcranial Direct Current Stimulation (tDCS) - Nicotine Dependence, Tobacco Smoking | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 160 | 2025-03-10 | 2025-08-12 |
| E-cigarette Cessation in Adults Who Co-use Cannabis Varenicline Pill, Contingency management, Counseling - Nicotine Dependence, Tobacco Use Disorder | Phase 4 | Recruiting | Medical University of South Carolina | 105 | 2025-02-19 | 2026-06-12 |
| Beta-Adrenergic Modulation of Drug Cue Reactivity Propranolol, Nicotine Patch, Placebo Propranolol - Tobacco Use Disorder, Nicotine Dependence | Phase 4 | Recruiting | University of Oklahoma | 80 | 2024-11-26 | 2026-04-28 |
| C-Raven, a Virtual Tobacco Cessation Intervention in the Community C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker - Tobacco Dependence | Phase 4 | Completed | Johns Hopkins University | 10 | 2024-10-30 | 2026-02-02 |
| Transcranial Magnetic Stimulation for Nicotine Dependence: An Effectiveness-Implementation Trial Brainsway H4 deep Repetitive Transcranial Magnetic Stimulation (rTMS) coil, Nicotine replacement - Tobacco Use Disorder, Psychiatric Disorder | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 40 | 2024-09-01 | 2025-12-11 |
| Emergency Department Management of Tobacco Use Disorder Nicotine Replacement Therapy Agent, West Virginia Quit Line - Tobacco Use Disorder, Tobacco Use Cessation | Phase 4 | Withdrawn | West Virginia University | 2024-08-01 | 2025-01-02 | |
| Testing C-Raven, a Virtual Tobacco Cessation Intervention, in the Community C-Raven Virtual Tobacco Cessation Counseling, Nicotine Replacement Product, Community Health Worker - Tobacco Dependence | Phase 4 | Completed | Johns Hopkins University | 5 | 2024-04-30 | 2025-09-10 |
| Implementation of Transcranial Magnetic Stimulation for Smoking Cessation Brainsway H4 deep rTMS coil and Brainsway stimulator system - Smoking | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 40 | 2024-03-30 | 2026-03-27 |
| Effectiveness of Combined Tobacco Treatment in Hospitalized Subjects Bupropion, Nicotine replacement therapy (Nicotine patches) - Tobacco Smoking, Tobacco Withdrawal | Phase 4 | Unknown | National Institute of Respiratory Diseases, Mexico | 134 | 2024-01-15 | 2024-02-23 |
| Cytisine for Smoking Cessation Cytisine, Placebo - Tobacco Use Disorder, Alcohol Use Disorder | Phase 4 | Completed | Centre for Addiction and Mental Health | 20 | 2023-02-08 | 2026-02-27 |
| Effectiveness of N-Acetylcysteine (NAC) in Motivational Enhancement Therapy for Nicotine Addiction n-acetylcysteine, Motivational Enhancement Therapy - Nicotine Dependence, Nicotine Addiction | Phase 4 | Completed | Universitas Indonesia | 90 | 2023-01-01 | 2024-10-08 |
| Smoking Cessation and Menstrual Cycle Phase Timing of nicotine replacement therapy start date, Nicotine Replacement Therapy Agent - Nicotine Dependence, Tobacco Smoking | Phase 4 | Recruiting | Centre for Addiction and Mental Health | 1200 | 2022-11-30 | 2026-03-19 |
| Varenicline for Nicotine Vaping Cessation in Adolescents Double Blind Varenicline, Double Blind Placebo, QuitVaping - Vaping, Nicotine Dependence | Phase 4 | Completed | Massachusetts General Hospital | 261 | 2022-06-22 | 2025-04-27 |
| Methadone-Maintained Smokers Switching to E-Cigarettes Electronic Cigarette, Nicotine Lozenge - Nicotine Dependence, Electronic Cigarette Use | Phase 4 | Completed | Butler Hospital | 183 | 2022-03-31 | 2026-08-20 |
| Comparative Effectiveness of Cystine Versus Nicotine Replacement Therapy Cytisine, Nicotine Replacement Therapy (NRT) - Nicotine Addiction | Phase 4 | Completed | Loma Linda University | 1307 | 2022-01-27 | 2024-09-19 |
Showing 20 of 95. Sign in to see all of them.
Smoking Cessation (44) · Smoking (21) · Vaping (9) · Schizophrenia (8) · Tobacco Use Cessation (7) · Cigarette Smoking (6) · Substance-Related Disorders (5) · Tobacco Smoking (5) · Psychotic Disorders (4) · Marijuana Abuse (3) · Mental Disorders (3) · Substance Withdrawal Syndrome (3) · Alcoholism (2) · Carcinoma, Hepatocellular (2)
Chemically-Induced Disorders (95) · Mental Disorders (92) · Substance-Related Disorders (90) · Behavior (71) · Health Behavior (51) · Smoking (18) · Tobacco Use (11) · Schizophrenia Spectrum and Other Psychotic Disorders (8) · Tobacco Smoking (6) · Mood Disorders (3) · Pathological Conditions, Signs and Symptoms (3) · Adenocarcinoma (2) · Alcohol-Related Disorders (2) · Bronchial Neoplasms (2) · Carcinoma (2)
Tobacco Use Cessation Devices (31) · Varenicline (25) · Bupropion (18) · Nicotine (10) · Nicotine Chewing Gum (10) · Nicotine Replacement Therapy (10) · Counseling (5) · Behavior Therapy (3) · Community Health Workers (3) · Acetylcysteine (2) · BID protein, human (2) · Electronic Nicotine Delivery Systems (2) · Motivational Interviewing (2) · Sugars (2) · Transcranial Magnetic Stimulation (2)
University of Wisconsin, Madison (13) · Centre for Addiction and Mental Health (9) · Massachusetts General Hospital (5) · University of Pennsylvania (5) · Johns Hopkins University (4) · National Institute on Drug Abuse (NIDA) (4) · University of California, San Francisco (3) · Albert Einstein College of Medicine (2) · Medical University of South Carolina (2) · University of California, San Diego (2) · VA Office of Research and Development (2) · Yale University (2) · American University of Beirut Medical Center (1) · Arizona State University (1) · Assistance Publique - Hôpitaux de Paris (1)
United States (71) · Canada (9) · France (2) · Austria (1) · China (1) · Germany (1) · Indonesia (1) · Lebanon (1) · Mexico (1) · Mongolia (1) · Spain (1) · Taiwan (1)
Timothy B Baker, PhD (4) · Alejandra Ellison-Barnes, MD (2) · Eden Evins, MD (2) · Laurie A Zawertailo, PhD (2) · Laurie Zawertailo, PhD (2) · Megan E Piper, PhD (2) · Peter Selby, MD, MHSc (2) · Randi Schuster, PhD (2) · A Eden Evins, MD, MPH (1) · Alasdair Barr, Ph.D (1) · Amy J Arouni, MD (1) · Andrea H. Weinberger, Ph.D. (1) · Andrew Strasser, PhD (1) · Anna Lembke, MD (1) · Barbara W Kamholz, Ph.D. (1)
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P50CA143188 (3), P50DA019706 (3), R01DA052583 (2), R01HL109031 (2), R37CA237245 (2), K23DA025736 (1), K24DA030301 (1), P01CA180945 (1), P50CA084724 (1), R01CA091912 (1), R01CA165080 (1), R01CA184211 (1), R01DA004174 (1), R01DA008075 (1), R01DA012289 (1)