70 completed, 6 recruiting, 4 withdrawn, 2 enrolling by invitation. 87 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 87 | Completed 70, Recruiting 6, Withdrawn 4, Enrolling by invitation 2, Terminated 2, Active not recruiting 1, Not yet recruiting 1, Unknown 1 |
Follow Tobacco Dependence: new trials by email Literature Review of Tobacco Dependence trials Research Report on Tobacco Dependence
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Chatbot for Online Support Groups to Treat Tobacco Addiction online quit-smoking support group with intelligent chatbot, online quit-smoking support group with unintelligent bot - Tobacco Dependence, Tobacco Use Disorder | Not applicable | Not yet recruiting | University of California, Irvine | 120 | 2026-12-01 | 2026-05-22 |
| Smoking Cessation Intervention Including Health Navigators to Address Unmet Social Needs of Parents Who Smoke CanCEASE with Health Navigator - Smoking Cessation, Tobacco Dependence | Not applicable | Recruiting | St. Justine's Hospital | 1000 | 2026-03-26 | 2026-07-24 |
| Cytisine vs Nicotine Replacement Therapy Cytisine, Nicotine replacement therapy (NRT) - Tobacco Dependence, COPD Asthma | Not applicable | Enrolling by invitation | Ottawa Hospital Research Institute | 200 | 2025-11-04 | 2026-03-17 |
| Reach Through Equitable Implementation in Utah Clinic Level: AAC - SDOH, AAC - Tobacco, Non-Bundled, Bundled - Tobacco Use Cessation, Tobacco Use | Not applicable | Recruiting | University of Utah | 1560 | 2025-02-13 | 2025-03-18 |
| Effect of Nicotine Gingival Fibroblast Intoxication on the Response of Periodontal Treatment periodontal non-surgical treatment - Periodontitis, Smoking Cessation | Not applicable | Enrolling by invitation | University of Liege | 56 | 2025-01-06 | 2026-04-22 |
| Effect of Yoga on Reducing Craving in Tobacco Dependent Individuals Yoga, WHO 5As model intervention - Tobacco Dependence | Not applicable | Recruiting | University of Pittsburgh | 96 | 2024-11-01 | 2026-06-05 |
| Positive Psychology for Smoking Cessation Individual and Group Treatment for Smoking Cessation - Mental Illness, Tobacco Dependence | Not applicable | Completed | Dartmouth-Hitchcock Medical Center | 16 | 2024-10-10 | 2025-12-18 |
| Harm Reduction for Smokers With Mental Illness SWITCH IT, E-cig Provision Only - Tobacco Dependence | Not applicable | Recruiting | Dartmouth-Hitchcock Medical Center | 250 | 2024-10-01 | 2026-01-15 |
| Use of Nicotine Pouches Among Daily Smokers 0 mg nicotine pouch, 3 mg nicotine pouch, 6 mg nicotine pouch - Tobacco Dependence | Not applicable | Recruiting | Milton S. Hershey Medical Center | 375 | 2024-09-17 | 2026-10-20 |
| Smoke-free Home Study in Subsidized Housing Smoke-free home resident intervention, Lay Health Worker coaching - Tobacco Dependence, Tobacco Smoking | Not applicable | Recruiting | University of California, San Francisco | 544 | 2024-07-12 | 2025-02-24 |
| Cooling Agent Pilot Among Adult Menthol Smokers Assigning cooling agent type cigarettes, Assigning traditional tobacco type cigarettes, Assigning menthol type cigarettes - Tobacco Dependence | Not applicable | Completed | University of Kansas Medical Center | 21 | 2024-06-24 | 2025-04-06 |
| Tobacco Cessation Care for Cancer Patients by Automated Interactive Outreach CareConnect, AutoReach, Biospecimen samples - Cancer, Tobacco Dependence | Not applicable | Completed | University of California, San Francisco | 400 | 2023-11-27 | 2026-10-29 |
| Equitable Smoking Relapse Prevention Quitbuddy, Control, SDoH Augmentation - Tobacco Use Disorder, Tobacco Dependence | Not applicable | Withdrawn | Bryan W. Heckman | 2023-10-02 | 2024-05-08 | |
| FRESH Delivers: An Innovative Approach to Reducing Tobacco Use Among Rural Smokers Smoking cessation counseling and food delivery, Smoking cessation counseling, Food delivery - Tobacco Cessation, Tobacco Dependence | Not applicable | Active not recruiting | University of Arkansas | 540 | 2023-08-09 | 2026-07-01 |
| Testing the Effect of ENDS Flavors on Neurotransmission Flavor - Tobacco Dependence | Not applicable | Completed | Milton S. Hershey Medical Center | 36 | 2023-06-01 | 2026-08-07 |
| DBT for Smoking Cessation in High Risk Veterans DBT-C, Treatment as usual - Tobacco Dependence, Suicidal | Not applicable | Completed | Veterans Medical Research Foundation | 67 | 2023-05-01 | 2026-01-08 |
| Assessment of Biomarkers in Children to Help Parents Quit Tobacco CEASE, CEASE + BIO - Tobacco Dependence | Not applicable | Completed | Massachusetts General Hospital | 865 | 2023-01-20 | 2026-06-15 |
| Interactive Mobile Doctor (iMD) to Promote Tobacco Cessation Among Cancer Patients Interactive Mobile Doctor (iMD) - Tobacco Dependence, Tobacco Use Cessation | Not applicable | Completed | University of California, San Francisco | 30 | 2022-11-15 | 2025-05-28 |
| Does Switching to Nicotine Containing Electronic Cigarettes Reduce Health Risk Markers Nicotine-Containing Electronic Cigarette, Non-Nicotine Electronic Cigarette - Tobacco Dependence | Not applicable | Completed | Milton S. Hershey Medical Center | 105 | 2022-04-22 | 2025-03-27 |
| Mixed Presentation on Social Media Mixed-Presentation of Content - Tobacco Use, Tobacco Dependence | Not applicable | Completed | University of Pennsylvania | 828 | 2021-11-15 | 2022-10-28 |
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Tobacco Use Disorder (87) · Smoking Cessation (35) · Smoking (24) · Tobacco Smoking (14) · Cigarette Smoking (11) · Tobacco Use Cessation (11) · Tobacco Use (7) · Behavior, Addictive (6) · Substance-Related Disorders (6) · Vaping (4) · Mental Disorders (3) · Alcoholism (2) · Anxiety Disorders (2) · Cardiovascular Diseases (2) · Harm Reduction (2)
Chemically-Induced Disorders (87) · Mental Disorders (84) · Substance-Related Disorders (81) · Behavior (64) · Health Behavior (41) · Tobacco Use (11) · Smoking (9) · Compulsive Behavior (6) · Impulsive Behavior (6) · Pathological Conditions, Signs and Symptoms (4) · Alcohol-Related Disorders (2) · Body Weight (2) · Cardiovascular Diseases (2) · Nutrition Disorders (2) · Nutritional and Metabolic Diseases (2)
Nicotine (11) · Nicotine Chewing Gum (7) · Nicotine Replacement Therapy (3) · Tobacco Use Cessation Devices (3) · Varenicline (3) · Yoga (3) · Flavoring Agents (2) · Health (2) · Tobacco Products (2) · Control Groups (1) · Crisis Intervention (1) · Diet (1) · Electronic Nicotine Delivery Systems (1) · Exercise (1) · Fish Oils (1)
McNeil AB (13) · Milton S. Hershey Medical Center (8) · University of California, San Francisco (5) · Dartmouth-Hitchcock Medical Center (4) · H. Lee Moffitt Cancer Center and Research Institute (3) · Massachusetts General Hospital (3) · Stanford University (3) · VA Office of Research and Development (3) · Centre for Addiction and Mental Health (2) · Click Therapeutics, Inc. (2) · Mayo Clinic (2) · Ottawa Hospital Research Institute (2) · The Miriam Hospital (2) · University of Arkansas (2) · University of Houston (2)
United States (59) · Sweden (13) · Canada (4) · Belgium (1) · India (1) · Ireland (1) · Israel (1) · United Kingdom (1)
Elisabeth Kruse, PhD (14) · Jonathan Foulds, PhD (3) · Gary L. Humfleet, PhD (2) · Janice Tsoh, PhD (2) · Jonathan P Winickoff, MD, MPH (2) · Judith J Prochaska, PhD, MPH (2) · A. Eden Evins, MD, MPH (1) · Andrea Hobkirk, PhD (1) · Anne Joseph, MD, MPH (1) · Brian M Iacoviello, PhD (1) · Britta Hahn, Ph.D. (1) · Brooke Kauffman, M.A. (1) · Bryan W Heckman, Ph.D. (1) · Chelsey Schlechter, MPH, PhD (1) · Christine E Sheffer, PhD (1)
PMID 21317630, PMID 21785963, PMID 22011421, PMID 22695211, PMID 24467257, PMID 24878686, PMID 25074396, PMID 25209524, PMID 25419703, PMID 26422724, PMID 26916879, PMID 27797659, PMID 27856940, PMID 28158558, PMID 28442453, PMID 28483741, PMID 28673312, PMID 28747857, PMID 29025502, PMID 29137560, PMID 29504780, PMID 29864548, PMID 30295912, PMID 30385649, PMID 30422224, PMID 30521040, PMID 30858346, PMID 30981026, PMID 31157864, PMID 31169077, PMID 31403675, PMID 33478466, PMID 33947346, PMID 34306222, PMID 34306227, PMID 34849423, PMID 35363874, PMID 35603037, PMID 35710334, PMID 36322562, PMID 36335079, PMID 36480510, PMID 36933290, PMID 37408953, PMID 38873183, PMID 40071390, PMID 40729126, PMID 42154468
2008 (6), P50DA036107 (2), 1IK2CX000918-01A1 (1), 2005 (1), 2009 (1), D43TW009114 (1), F31DA043390 (1), F31DA046127 (1), K23DA032578 (1), K23DA045081 (1), R01CA106667 (1), R01CA127127 (1), R01CA129771 (1), R01CA152093 (1), R01CA201429 (1)