8 completed, 4 unknown, 2 not yet recruiting, 1 active not recruiting. 17 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 17 | Completed 8, Unknown 4, Not yet recruiting 2, Active not recruiting 1, Suspended 1, Terminated 1 |
Follow Tinnitus: new trials by email Literature Review of Tinnitus trials Research Report on Tinnitus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Emerging Indications for Hyperbaric Oxygen Treatment Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis | Phase 4 | Not yet recruiting | Jay C. Buckey Jr. | 100 | 2026-11-01 | 2026-09-09 |
| Comparing Migraine Preventive Therapies vs. Anti-CGRP Therapies for Tinnitus in Patients With Migraine (COMPACT-PM) Galcanezumab, Erenumab 70 mg, Eptinezumab - Migraine Associated Vertigo, Tinnitus | Phase 4 | Not yet recruiting | Stanford University | 120 | 2026-07-01 | 2026-06-17 |
| Management of Acute Tinnitus With Migraine Medications Nortriptyline, Topiramate, Paroxetine - Tinnitus | Phase 4 | Suspended | University of California, Irvine | 100 | 2025-06-01 | 2026-10-27 |
| Efficacy of Donepezil in Patients With Chronic Tinnitus Donepezil group, Placebo group - Tinnitus | Phase 4 | Active not recruiting | University of Sao Paulo | 70 | 2021-11-19 | 2025-09-04 |
| Intratympanic Administration of N-acetylcysteine for Protection of Cisplatin-induced Ototoxicity N-acetyl cysteine - Ototoxic Hearing Loss, Ototoxic Hearing Loss, Bilateral | Phase 4 | Terminated | Centre Hospitalier Universitaire Saint Pierre | 19 | 2021-07-10 | 2023-10-24 |
| Effectiveness of Intratympanic Dexamethasone With Ligmocaine for Alleviation of Tinnitus Dexamethasone - Tinnitus | Phase 4 | Unknown | Combined Military Hospital, Pakistan | 264 | 2021-03-01 | 2021-03-15 |
| Treatment of Tinnitus With Migraine Medications Nortriptyline + Topiramate, Verapamil + Paroxetine, Placebo - Tinnitus, Subjective, Tinnitus | Phase 4 | Completed | University of California, Irvine | 78 | 2019-09-26 | 2026-04-16 |
| Nitrous Oxide Treatment for Tinnitus Nitrous oxide gas for inhalation, Placebo gas for inhalation - Tinnitus | Phase 4 | Completed | Washington University School of Medicine | 40 | 2016-10-01 | 2018-12-14 |
| Lidoderm Patch (Lidocaine 5%) for Tinnitus Treatment Lidoderm patch (Lidocaine 5% patch), Tegaderm patch. (neutral patch, containing no drug), blood test- serum lidocain levels - Tinnitus | Phase 4 | Unknown | HaEmek Medical Center, Israel | 58 | 2016-04-01 | 2018-02-28 |
| Treating Tinnitus Using Eutectic Mixture of Local Anesthetics (EMLA) 5% Cream EMLA cream 5%, cetomacrogol cream (lotion cream) - Tinnitus | Phase 4 | Completed | HaEmek Medical Center, Israel | 142 | 2014-11-01 | 2018-02-28 |
| The Effects of the Drugs Used in Hypotensive Anaesthesia on Cochlea Dexmedetomidine, esmolol - Anesthesia; Adverse Effect, Reflex, Abnormal | Phase 4 | Completed | TC Erciyes University | 47 | 2014-01-01 | 2014-11-10 |
| The Effects of Caffeine on Vestibular Evoked Myogenic Potentials in Healthy Subjects Caffeine - Healthy Subjects | Phase 4 | Unknown | Hospital do Servidor Publico Estadual | 25 | 2012-01-01 | 2012-10-02 |
| Acoustic Coordinated Reset (CR®) Neuromodulation for the Treatment of Chronic Tonal Tinnitus ("RESET Real Life") ANM T30 CR®-System - Tinnitus | Phase 4 | Completed | ANM Adaptive Neuromodulation GmbH | 200 | 2011-11-01 | 2014-07-11 |
| Deanxit and Rivotril in Tinnitus Patients Deanxit, Lactose placebo - Tinnitus | Phase 4 | Completed | University Hospital, Antwerp | 50 | 2009-02-01 | 2009-08-11 |
| Phase Out in Tinnitus Patients Phase Out treatment in pure tone tinnitus patients - Tinnitus | Phase 4 | Completed | University Hospital, Antwerp | 40 | 2008-03-01 | 2009-03-03 |
| Customized Acoustic Stimulation for Long Term Medical Benefit for the Relief of Tinnitus and Hyperacusis Oasis - Tinnitus, Hyperacusis | Phase 4 | Unknown | Neuromonics, Inc. | 53 | 2007-06-01 | 2009-08-25 |
| Tinnitus Treatment by Structured Cognitive Behavioral Therapy Cognitive behavioral therapy, Waiting group - Tinnitus | Phase 4 | Completed | University Hospital Tuebingen | 286 | 2000-10-01 | 2008-07-22 |
Migraine Disorders (2) · Calciphylaxis (1) · Colitis, Ulcerative (1) · Color Vision Defects (1) · Craniocerebral Trauma (1) · Crohn Disease (1) · Dizziness (1) · Enterocolitis, Pseudomembranous (1) · Epidermolysis Bullosa (1) · Frostbite (1) · Graft vs Host Disease (1) · Hyperacusis (1) · Hypospadias (1) · Invasive Fungal Infections (1)
Ear Diseases (17) · Hearing Disorders (17) · Nervous System Diseases (17) · Neurologic Manifestations (17) · Otorhinolaryngologic Diseases (17) · Pathological Conditions, Signs and Symptoms (17) · Sensation Disorders (17) · Signs and Symptoms (17) · Brain Diseases (3) · Central Nervous System Diseases (3) · Headache Disorders (3) · Headache Disorders, Primary (3) · Eye Diseases (2) · Pathologic Processes (2) · Wounds and Injuries (2)
Nortriptyline (3) · Topiramate (3) · Verapamil (3) · Paroxetine (2) · Acetylcysteine (1) · Amitriptyline (1) · Caffeine (1) · Cognitive Behavioral Therapy (1) · Dexamethasone (1) · Dexmedetomidine (1) · Endothelium-Dependent Relaxing Factors (1) · Hearing (1) · Inhalation (1) · Lidocaine (1) · Oxygen (1)
HaEmek Medical Center, Israel (2) · University Hospital, Antwerp (2) · University of California, Irvine (2) · ANM Adaptive Neuromodulation GmbH (1) · Centre Hospitalier Universitaire Saint Pierre (1) · Combined Military Hospital, Pakistan (1) · Hospital do Servidor Publico Estadual (1) · Jay C. Buckey Jr. (1) · Neuromonics, Inc. (1) · Stanford University (1) · TC Erciyes University (1) · University Hospital Tuebingen (1) · University of Sao Paulo (1) · Washington University School of Medicine (1)
United States (4) · Belgium (3) · Brazil (2) · Germany (2) · Israel (1) · Pakistan (1) · Turkey (Türkiye) (1)
Ana Maria Almeida Sousa, MD (1) · Avi Shupak, MD (1) · Fabio Akira Suzuki, PhD (1) · Gunhan Gokahmetoglu, M.D (1) · Hamid R Djalilian, MD (1) · Hans P. Zenner, M.D. (1) · Jay Buckey (1) · Jay F Piccirillo, MD (1) · Kristen K. Steenerson (1) · Matthew Fitzgerald (1) · Mehdi Abouzari, MD, PhD (1) · Olivier Meeus, MD (1) · Uwe Brinkmann, Dr. med. (1)