Graft vs Host Disease: Clinical Trials

1,350 trials for Graft vs Host Disease, newest first

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708 completed, 169 unknown, 157 terminated, 154 recruiting. 511 Phase 2, 267 Not applicable, 250 Phase 1, 161 Phase 3, 74 Phase 4.

By phase and status

PhaseTrialsStatus
Phase 2511Completed 261, Terminated 74, Unknown 64, Recruiting 57, Active not recruiting 24, Withdrawn 21, Not yet recruiting 6, Enrolling by invitation 3, Suspended 1
Not applicable267Completed 126, Unknown 43, Recruiting 40, Terminated 27, Active not recruiting 15, Not yet recruiting 11, Withdrawn 3, Enrolling by invitation 2
Phase 1250Completed 126, Terminated 35, Unknown 29, Recruiting 24, Active not recruiting 16, Withdrawn 10, Not yet recruiting 7, Enrolling by invitation 2, Suspended 1
Phase 3161Completed 101, Terminated 24, Unknown 12, Recruiting 9, Active not recruiting 7, Withdrawn 5, Not yet recruiting 3
Phase 474Completed 45, Terminated 6, Unknown 6, Withdrawn 6, Not yet recruiting 4, Recruiting 4, Active not recruiting 3
Early Phase 116Completed 7, Withdrawn 3, Terminated 2, Active not recruiting 1, Not yet recruiting 1, Recruiting 1, Unknown 1

Follow Graft vs Host Disease: new trials by email Literature Review of Graft vs Host Disease trials Research Report on Graft vs Host Disease

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Mindfulness Intervention to Reduce Patient Reported Symptoms in Patients With Chronic Graft-Versus-Host Disease
Biospecimen Collection, Mindfulness Relaxation, Survey Administration - Chronic Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm
Not applicableRecruitingCity of Hope Medical Center172027-03-012026-10-16
CD34+ Enriched Transplants to Treat Myelodysplastic Syndrome
Busulfan, Melphalan, Fludarabine - Myelodysplastic Syndromes, Graft Vs Host Disease
Not applicableNot yet recruitingGuenther Koehne622027-01-012026-10-13
CSF-1R Inhibitor, Axatilimab, for Prevention of Acute and Chronic GVHD After HLA-Matched Related and Unrelated Donor Allogeneic Stem Cell Transplantation
Hematopoietic Cell Transplantation, Cyclophosphamide, Tacrolimus - Graft -Versus-host-disease
Phase 2Not yet recruitingMedical College of Wisconsin722026-11-012026-09-08
Emerging Indications for Hyperbaric Oxygen Treatment
Hyperbaric oxygen treatment (HBOT), 100% Oxygen - Post-COVID-19 Condition, Ulcerative Colitis
Phase 4Not yet recruitingJay C. Buckey Jr.1002026-11-012026-09-09
Vitamin C With Steroids for Gastrointestinal GVHD
Vitamin C (Ascorbic Acid) - Graft-versus-host-disease (GVHD), Gastrointestinal
Early Phase 1Not yet recruitingBaylor College of Medicine352026-11-012026-10-13
Kinetic Analysis of Immune Cells in Blood and Chronic Graft-Versus-Host Disease-Affected Tissues After Allogeneic Hematopoietic Cell Transplantation
Non-Interventional Study - Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm
RecruitingCity of Hope Medical Center752026-11-012026-10-05
CK0802 for Treatment of Steroid Refractory Graft vs. Host Disease (GVHD)
CK0802 (Allogeneic, Cryopreserved, Cord blood-derived T-regulatory cells, cells that are not HLA matched) - Steroid Refractory Graft Versus Host Disease
Phase 1 / Phase 2Not yet recruitingCellenkos, Inc.122026-11-012026-10-21
Nutritional Intervention for Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Enteral Nutritional Suspension (TP-MCT), Routine nutritional guidance, Biospecimen-Stool Sample Collection - Hematopoietic Stem Cell Transplantation (HSCT), Malnutrition (Calorie)
Not applicableNot yet recruitingInstitute of Hematology & Blood Diseases Hospital, China1602026-10-122026-09-30
Use of Bone Marrow Stem Cells (MesenCell) for the Treatment of Patients With Chronic Graft-versus-host Disease
Mesenchymal Stem Cell Infusion - Graft vs Host Disease, Mesenchymal Stem Cell Transplantation
Phase 1Not yet recruitingPontifícia Universidade Católica do Paraná202026-10-012026-09-17
Sirolimus+Ruxolitinib+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to CNI
Sirolimus, Ruxolitinib, MMF - Acute Leukemia, Myelodysplastic Syndromes
Phase 1 / Phase 2Not yet recruitingPeking University People's Hospital402026-10-012026-09-09
Evaluation of Allogenic Mesenchymal Stem Cell (MSC) Injection Therapy for Refractory Graft-versus-Host Disease (GVHD) Unresponsive to Conventional Treatments
Subconjuntival injection of expanded allogenic adult adipose tissue-derived mesenchymal stem cells (ASC - Dry Eye Disease (DED), Graft-Versus-Host Disease(GVHD)
Phase 2Not yet recruitingInstituto de Investigación Biomédica de Salamanca302026-10-012026-09-03
Evaluating the Effects of Propionate and Butyrate Supplementation on the Intestinal Health of Healthy Volunteers
Biospecimen Collection, Microencapsulated Sodium Butyrate, Microencapsulated Sodium Propionate - Graft Versus Host Disease, Hematopoietic and Lymphatic System Neoplasm
Phase 1Not yet recruitingCity of Hope Medical Center122026-09-302026-05-28
A Preliminary Clinical Study on the Efficacy of Cyclophosphamide and Sirolimus Combined With VIC-1911 in Preventing Graft-versus-Host Disease After Haploidentical Stem Cell Transplantation in Children
1mg /kg VIC-1911 - GVHD (Acute or Chronic)
Phase 1RecruitingShanghai Jiao Tong University School of Medicine92026-09-282026-10-20
FMT for Pediatric SR-aGVHD
Fecal Microbial Transplantation - Acute Graft Versus Host Disease in Intestine
Phase 1 / Phase 2RecruitingBambino Gesù Hospital and Research Institute202026-09-172026-10-20
A Study to Investigate the Efficacy and Safety of Belumosudil Compared With Best Available Therapy in Participants Aged 12 Years or Older With Chronic Graft-versus-host Disease
Belumosudil, Best available therapy (BAT) - Chronic Graft Versus Host Disease
Phase 3Not yet recruitingSanofi3562026-09-072026-09-15
A Multicentre Randomised Controlled Trial Evaluating the Efficacy of the SMILE™ Module for Improving Short-term Periodontal Outcomes, Compliance, and Acceptability Among Clinical Dental Students
SMILE Module, Conventional Toothbrushing Module - Gingivitis, Gingivitis; Chronic
Not applicableNot yet recruitingNational University of Malaysia662026-09-012026-07-15
A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase III Trial of Remestemcel-L-rknd Added to Ruxolitinib for Grade III-IV Steroid-Refractory Acute Graft-Versus-Host Disease
Remestemcel-L-rknd, Placebo - GVHD - Graft-Versus-Host Disease
Phase 3Not yet recruitingMesoblast, Ltd.1802026-08-312026-05-05
Efficacy of Bee Venom Phonophoresis in Treating Chronic Sinusitis:
Bee Venom Phonophoresis, Standard Care (oral decongestants + saline nasal irrigation) - Chronic Sinusitis, Acute Sinusitis
Not applicableNot yet recruitingSinai University302026-08-152026-08-04
A Study to Investigate Safety of Belumosudil in Participants Aged 12 Years and Above, With Chronic Graft-versus-host Disease (cGVHD)
Belumosudil - Chronic Graft Versus Host Disease
Phase 4Not yet recruitingSanofi262026-08-102026-05-12
Study to Compare the Plasma Concentration of Belumosudil Given as an Oral Suspension and as a Tablet to Healthy Adult Male Participants
Belumosudil - Chronic Graft Versus Host Disease
Phase 1Not yet recruitingSanofi582026-08-062026-07-24

Showing 20 of 1350. Sign in to see all of them.

Narrower conditions

Bronchiolitis Obliterans Syndrome (703)  ·  Leukemia (138)  ·  Myelodysplastic Syndromes (119)  ·  Leukemia, Myeloid, Acute (103)  ·  Precursor Cell Lymphoblastic Leukemia-Lymphoma (103)  ·  Hematologic Neoplasms (87)  ·  Leukemia, Lymphocytic, Chronic, B-Cell (83)  ·  Lymphoma (74)  ·  Lymphoma, Non-Hodgkin (68)  ·  Lymphoma, Follicular (67)  ·  Multiple Myeloma (64)  ·  Hodgkin Disease (62)  ·  Myeloproliferative Disorders (53)  ·  Leukemia, Myelogenous, Chronic, BCR-ABL Positive (52)

Broader conditions

Immune System Diseases (1332)  ·  Lung Diseases (709)  ·  Respiratory Tract Diseases (709)  ·  Lung Diseases, Obstructive (706)  ·  Bronchial Diseases (705)  ·  Bronchiolitis (705)  ·  Bronchitis (703)  ·  Organizing Pneumonia (702)  ·  Bronchiolitis Obliterans (685)  ·  Pathological Conditions, Signs and Symptoms (439)  ·  Hemic and Lymphatic Diseases (355)  ·  Hematologic Diseases (314)  ·  Neoplasms (301)  ·  Pathologic Processes (276)

Interventions

Tacrolimus (98)  ·  Cyclophosphamide (94)  ·  Mycophenolic Acid (70)  ·  Sirolimus (67)  ·  Cyclosporine (66)  ·  Methotrexate (65)  ·  Busulfan (45)  ·  Antilymphocyte Serum (42)  ·  Methylprednisolone (41)  ·  fludarabine phosphate (41)  ·  fludarabine (40)  ·  Prednisone (32)  ·  ruxolitinib (32)  ·  Rituximab (29)  ·  Filgrastim (25)

Sponsors

Fred Hutchinson Cancer Center (33)  ·  Dana-Farber Cancer Institute (29)  ·  National Heart, Lung, and Blood Institute (NHLBI) (29)  ·  Novartis Pharmaceuticals (26)  ·  M.D. Anderson Cancer Center (24)  ·  National Cancer Institute (NCI) (22)  ·  Incyte Corporation (17)  ·  H. Lee Moffitt Cancer Center and Research Institute (15)  ·  Assistance Publique - Hôpitaux de Paris (14)  ·  City of Hope Medical Center (13)  ·  Hoffmann-La Roche (12)  ·  Massachusetts General Hospital (12)  ·  Karolinska Institutet (10)  ·  National Institute of Allergy and Infectious Diseases (NIAID) (10)  ·  AstraZeneca (9)

Countries

United States (673)  ·  France (106)  ·  Germany (99)  ·  China (95)  ·  Canada (93)  ·  Italy (90)  ·  Spain (79)  ·  United Kingdom (78)  ·  Belgium (61)  ·  Australia (49)  ·  Israel (46)  ·  South Korea (45)  ·  Netherlands (40)  ·  Turkey (Türkiye) (39)  ·  Poland (36)

Top investigators

Stephanie Lee (7)  ·  A. John Barrett, M.D. (6)  ·  Amin Alousi, MD (6)  ·  Michael Y Shapira, MD (6)  ·  Pooja Khandelwal, MD (6)  ·  Amandeep Salhotra (4)  ·  Barbara Jean Bambach, MD (4)  ·  Christopher James, PA (4)

Results publications

PMID 23065508, PMID 23524640, PMID 32816215, PMID 29316837, PMID 32160294, PMID 36240296, PMID 42133908, PMID 16551963, PMID 19282026, PMID 20965785, PMID 23802653, PMID 23861248, PMID 24432712, PMID 25287629, PMID 26149717, PMID 26408225, PMID 28396102, PMID 30904387, PMID 31173898, PMID 31260802, PMID 32416453, PMID 33811823, PMID 34102349, PMID 34126278, PMID 34260836, PMID 34265047, PMID 34433773, PMID 34773261, PMID 35235189, PMID 35689489, PMID 35781099, PMID 36440464, PMID 36608310, PMID 36791280, PMID 37341189, PMID 37698881, PMID 38696034, PMID 39704205, PMID 40472328, PMID 41871072, PMID 42180389, PMID 5449164, PMID 10387937, PMID 10619108, PMID 10845900, PMID 10845940, PMID 10997973, PMID 11172169, PMID 11222360, PMID 11301861

NIH funding

2016 (11), P30CA015704 (11), 2017 (9), P30CA033572 (9), 2015 (7), 2014 (6), 2019 (6), 2009 (5), 2018 (5), P30CA006973 (5), 2023 (4), P01CA015396 (4), P30CA068485 (4), U01HL069294 (4), 2025 (3)